Microbubble array diffusion assay for the detection of cell secreted factors

Lab on a Chip

Volumn 14, Issue 18, 2014, Pages 3640-3650

  Bobo, Bryan ^a   Phelan, Dana ^a   Rebhahn, Jonathan ^b   Piepenbrink, Michael S ^b   Zheng, Bo ^b   Mosmann, Tim R ^b   Kobie, James J ^b   DeLouise, Lisa A ^a,b  

^a University of Rochester   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; EPITOPE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; IMMUNOGLOBULIN; SIGNAL PEPTIDE;

ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; B LYMPHOBLAST; B LYMPHOCYTE; BINDING AFFINITY; CELL ASSAY; CELL CULTURE; CELL GROWTH; CELL SELECTION; DIFFUSION; ENZYME LINKED IMMUNOSPOT ASSAY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HYBRIDOMA CELL LINE; IMMORTALIZED CELL LINE; IMMUNOPRECIPITATION; LAB ON A CHIP; MICROBUBBLE; MICROBUBBLE ARRAY DIFFUSION ASSAY; PRIORITY JOURNAL; SIGNAL DETECTION; T LYMPHOBLAST; CELL LINE; CELL SEPARATION; CYTOLOGY; DEVICES; FEMALE; GENETICS; HIGH THROUGHPUT SEQUENCING; MALE; METABOLISM; PROCEDURES; SECRETION (PROCESS);

B-LYMPHOCYTES; CELL LINE; CELL SEPARATION; FEMALE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; IMMUNOGLOBULINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LAB-ON-A-CHIP DEVICES; MALE; MICROBUBBLES;

EID: 84905868092     PISSN: 14730197     EISSN: 14730189     Source Type: Journal    
DOI: 10.1039/c4lc00580e     Document Type: Article

References (33)

1. S. A. Small S. Gandy Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis Neuron 2006 52 1 15 31
2. B. El Debs et al., Functional single-cell hybridoma screening using droplet-based microfluidics Proc. Natl. Acad. Sci. U. S. A. 2012 109 29 11570 11575
3. M. Reichen et al., Microfabricated modular scale-down device for regenerative medicine process development PLoS One 2012 7 12 e52246
4. P. Tiwari, Monoclonal Antibody Industry 2013 Global and China Market Analysis in New Research Report at RnRMarketResearch.com, 2013
5. M. Flego et al., Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases BMC Med. 2013 11 4
6. G. P. Adams L. M. Weiner Monoclonal antibody therapy of cancer Nat. Biotechnol. 2005 23 9 1147 1157
7. V. Bruno G. Battaglia F. Nicoletti The advent of monoclonal antibodies in the treatment of chronic autoimmune diseases Neurol. Sci. 2011 31 Suppl. 3 283 288
8. C. Love A microengraving method for rapid selection of single cells producing antigen specific antibodies Nat. Biotechnol. 2006 24 6 703 707
9. W. D. Harriman et al., Antibody discovery via multiplexed single cell characterization J. Immunol. Methods 2009 341 1-2 135 145
10. F. De Masi et al., High throughput production of mouse monoclonal antibodies using antigen microarrays Proteomics 2005 5 16 4070 4081
11. A. O. Ogunniyi et al., Screening individual hybridomas by microengraving to discover monoclonal antibodies Nat. Protoc. 2009 4 5 767 782
12. A. Jin et al., A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood Nat. Med. 2009 15 9 1088 1092
13. U. B. Giang et al., Microfabrication of cavities in polydimethylsiloxane using DRIE silicon molds Lab Chip 2007 7 12 1660 1662
14. U. B. Giang M. C. Jones M. J. Kaule C. R. Virgile Q. Pu L. A. Delouise Quantitative analysis of spherical microbubble cavity array formation in thermally cured polydimethylsiloxane for use in cell sorting applications Biomed. Microdevices 2014 16 1 55 67
15. S. Chandrasekaran et al., Microenvironment induced spheroid to sheeting transition of immortalized human keratinocytes (HaCaT) cultured in microbubbles formed in polydimethylsiloxane Biomaterials 2011 32 29 7159 7168
16. M. C. Jones J. J. Kobie L. A. Delouise Characterization of cell seeding and specific capture of B cells in microbubble well arrays Biomed. Microdevices 2013 15 3 453 463
17. S. Agastin et al., Continuously perfused microbubble array for 3D tumor spheroid model Biomicrofluidics 2011 5 2 24110
18. J. Nowicky et al., Biological activity of ukrain in vitro and in vivo Chemioterapia 1987 6 2 Suppl. 683 685
19. C. Richardson et al., Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus J. Immunol. 2013 191 10 4926 4939
20. A. D. Henn et al., Modulation of single-cell IgG secretion frequency and rates in human memory B cells by CpG DNA, CD40L, IL-21, and cell division J. Immunol. 2009 183 5 3177 3187
21. G. Blanchard-Rohner et al., Appearance of peripheral blood plasma cells and memory B cells in a primary and secondary immune response in humans Blood 2009 114 24 4998 5002
22. M. Sullivan et al., Harnessing the immune system's arsenal: producing human monoclonal antibodies for therapeutics and investigating immune responses F1000 Biol. Rep. 2011 3 17
23. Mayo Clinic Staff, Monoclonal antibody drugs for cancer treatment: How they work, 2014, http://www.mayoclinic.org/diseases-conditions/cancer/in-depth/ monoclonal-antibody/art-20047808
24. ATCC, ATCC Primary Cell Culture Guide, ATCC, Manassas, VA, 2012, http://www.atcc.org/~/media/PDFs/Culture%20Guides/Primary-Cell-Culture-Guide. ashx
25. A. Kumar et al., Long-term culture of primary B cells and in vitro expression of an exogenous gene Immunol. Lett. 1995 47 3 193 197
26. T. Boenisch, Antibodies in Dako Pathology Education Guide, Immunohistochemical (HIC) Staining Methods, ed., G. L. Kumar, and, L. Rudbeck, 5th edn, 2009, ch. 1, http://www.dako.com/08002-ihc-staining-methods-5ed.pdf
27. K. Saadin et al., Enrichment of tumor-initiating breast cancer cells within a mammosphere-culture microdevice Biomed. Microdevices 2013 15 4 645 655
28. M. Perego et al., Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells J. Invest. Dermatol. 2010 130 7 1877 1886
29. G. B. Faguet J. F. Agee A simple technique for the rapid enrichment of class and subclass hybridoma switch variants. A 1000-fold enrichment in half the time, for half the cost J. Immunol. Methods 1993 165 2 217 224
30. D. M. Sze et al., Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival J. Exp. Med. 2000 192 6 813 821
31. J. Cooperman et al., Cell division rates of primary human precursor B cells in culture reflect in vivo rates Stem Cells 2004 22 6 1111 1120
32. C. Stahli et al., High frequencies of antigen-specific hybridomas: dependence on immunization parameters and prediction by spleen cell analysis J. Immunol. Methods 1980 32 3 297 304
33. M. Rieger et al., Efficient hybridoma screening technique using capture antibody based microarrays Anal. Chem. 2009 81 6 2373 2377