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Volumn 111, Issue 7, 2014, Pages 1334-1344

Brain-gut interaction in the pathophysiology of IBS

Author keywords

[No Author keywords available]

Indexed keywords

AFFERENT PATHWAYS; BRAIN; HUMANS; INTESTINES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IRRITABLE BOWEL SYNDROME; MAGNETIC RESONANCE IMAGING; NEUROPEPTIDES; PAIN PERCEPTION;

EID: 84905818568     PISSN: 04466586     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (92)
  • 1
    • 33646201266 scopus 로고    scopus 로고
    • The functional gastrointestinal disorders and the Rome III process
    • Drossman DA : The functional gastrointestinal disorders and the Rome III process. Gastroenterology 130; 1377-1390 : 2006
    • (2006) Gastroenterology , vol.130 , pp. 1377-1390
    • Drossman, D.A.1
  • 3
    • 0028338434 scopus 로고
    • Basic and clinical aspects of visceral hyperalgesia
    • Mayer EA, Gebhart GF : Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 107; 271-293 : 1994
    • (1994) Gastroenterology , vol.107 , pp. 271-293
    • Mayer, E.A.1    Gebhart, G.F.2
  • 4
    • 0025630001 scopus 로고
    • Brain magnetic resonance imaging with contrast dependent on blood oxygenation
    • Ogawa S, Lee TM, Kay AR, et al : Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci U S A 87; 9868-9872 : 1990
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9868-9872
    • Ogawa, S.1    Lee, T.M.2    Kay, A.R.3
  • 5
    • 0037370204 scopus 로고    scopus 로고
    • Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome
    • Drossman DA, Ringel Y, Vogt BA, et al : Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome. Gastroenterology 124; 754-761 : 2003
    • (2003) Gastroenterology , vol.124 , pp. 754-761
    • Drossman, D.A.1    Ringel, Y.2    Vogt, B.A.3
  • 6
    • 78650505214 scopus 로고    scopus 로고
    • Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome
    • Tillisch K, Mayer EA, Labus JS : Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology 140; 91-100 : 2011
    • (2011) Gastroenterology , vol.140 , pp. 91-100
    • Tillisch, K.1    Mayer, E.A.2    Labus, J.S.3
  • 7
    • 0032869019 scopus 로고    scopus 로고
    • Monkey insular cortex neurons respond to baroreceptive and somatosensory convergent inputs
    • Zhang ZH, Dougherty PM, Oppenheimer SM : Monkey insular cortex neurons respond to baroreceptive and somatosensory convergent inputs. Neuroscience 94; 351-360 : 1999
    • (1999) Neuroscience , vol.94 , pp. 351-360
    • Zhang, Z.H.1    Dougherty, P.M.2    Oppenheimer, S.M.3
  • 8
    • 0023951290 scopus 로고
    • Asymbolia for pain: A sensory-limbic disconnection syndrome
    • Berthier M, Starkstein S, Leiguarda R : Asymbolia for pain : a sensory-limbic disconnection syndrome. Ann Neurol 24; 41-49 : 1988
    • (1988) Ann Neurol , vol.24 , pp. 41-49
    • Berthier, M.1    Starkstein, S.2    Leiguarda, R.3
  • 9
    • 0033358873 scopus 로고    scopus 로고
    • Pain-related neurons in the human cingulate cortex
    • Hutchison WD, Davis KD, Lozano AM, et al : Pain-related neurons in the human cingulate cortex. Nat Neurosci 2; 403-405 : 1999
    • (1999) Nat Neurosci , vol.2 , pp. 403-405
    • Hutchison, W.D.1    Davis, K.D.2    Lozano, A.M.3
  • 10
    • 23944452264 scopus 로고    scopus 로고
    • Anterior cingulate cortical neuronal activity during perception of noxious thermal stimuli in monkeys
    • Iwata K, Kamo H, Ogawa A, et al : Anterior cingulate cortical neuronal activity during perception of noxious thermal stimuli in monkeys. J Neurophysiol 94; 1980-1991 : 2005
    • (2005) J Neurophysiol , vol.94 , pp. 1980-1991
    • Iwata, K.1    Kamo, H.2    Ogawa, A.3
  • 11
    • 0033001048 scopus 로고    scopus 로고
    • Pain sensitivity alterations as a function of lesion location in the parasylvian cortex
    • Greenspan JD, Lee RR, Lenz FA : Pain sensitivity alterations as a function of lesion location in the parasylvian cortex. Pain 81; 273-282 : 1999
    • (1999) Pain , vol.81 , pp. 273-282
    • Greenspan, J.D.1    Lee, R.R.2    Lenz, F.A.3
  • 12
    • 38349036203 scopus 로고    scopus 로고
    • Reduced brainstem inhibition during anticipated pelvic visceral pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syndrome
    • Berman SM, Naliboff BD, Suyenobu B, et al : Reduced brainstem inhibition during anticipated pelvic visceral pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syndrome. J Neurosci 28; 349-359 : 2008
    • (2008) J Neurosci , vol.28 , pp. 349-359
    • Berman, S.M.1    Naliboff, B.D.2    Suyenobu, B.3
  • 13
    • 0021921907 scopus 로고
    • The central neural connections of the area postrema of the rat
    • Shapiro RE, Miselis RR : The central neural connections of the area postrema of the rat. J Comp Neurol 234; 344-364 : 1985
    • (1985) J Comp Neurol , vol.234 , pp. 344-364
    • Shapiro, R.E.1    Miselis, R.R.2
  • 14
    • 84879188207 scopus 로고    scopus 로고
    • Changes in the modulation of spinal pain processing are related to severity in irritable bowel syndrome
    • Bouhassira D, Moisset X, Jouet P, et al : Changes in the modulation of spinal pain processing are related to severity in irritable bowel syndrome. Neurogastroenterol Motil 25; 623-e468 : 2013
    • (2013) Neurogastroenterol Motil , vol.25
    • Bouhassira, D.1    Moisset, X.2    Jouet, P.3
  • 15
    • 84880700509 scopus 로고    scopus 로고
    • Contributions of the cerebellum to disturbed central processing of visceral stimuli in irritable bowel syndrome
    • Rosenberger C, Thürling M, Forsting M, et al : Contributions of the cerebellum to disturbed central processing of visceral stimuli in irritable bowel syndrome. Cerebellum 12; 194-198 : 2013
    • (2013) Cerebellum , vol.12 , pp. 194-198
    • Rosenberger, C.1    Thürling, M.2    Forsting, M.3
  • 16
    • 77951667119 scopus 로고    scopus 로고
    • Altered brain structure in irritable bowel syndrome: Potential contributions of pre-existing and diseasedriven factors
    • Blankstein U, Chen J, Diamant NE, et al : Altered brain structure in irritable bowel syndrome : potential contributions of pre-existing and diseasedriven factors. Gastroenterology 138; 1783-1789 : 2010
    • (2010) Gastroenterology , vol.138 , pp. 1783-1789
    • Blankstein, U.1    Chen, J.2    Diamant, N.E.3
  • 17
    • 37849029806 scopus 로고    scopus 로고
    • Cortical thinning in IBS: Implications for homeostatic, attention, and pain processing
    • Davis KD, Pope G, Chen J, et al : Cortical thinning in IBS : implications for homeostatic, attention, and pain processing. Neurology 70; 153-154 : 2008
    • (2008) Neurology , vol.70 , pp. 153-154
    • Davis, K.D.1    Pope, G.2    Chen, J.3
  • 18
    • 84885022164 scopus 로고    scopus 로고
    • Thicker posterior insula is associated with disease duration in women with irritable bowel syndrome (IBS) whereas thicker orbitofrontal cortex predicts reduced pain inhibition in both IBS patients and controls
    • Piché M, Chen JI, Roy M, et al : Thicker posterior insula is associated with disease duration in women with irritable bowel syndrome (IBS) whereas thicker orbitofrontal cortex predicts reduced pain inhibition in both IBS patients and controls. J Pain 14; 1217-1226 : 2013
    • (2013) J Pain , vol.14 , pp. 1217-1226
    • Piché, M.1    Chen, J.I.2    Roy, M.3
  • 19
    • 77954080839 scopus 로고    scopus 로고
    • Regional gray matter density changes in brains of patients with irritable bowel syndrome
    • Seminowicz DA, Labus JS, Bueller JA, et al : Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology 139 ; 48-57.e2 : 2010
    • (2010) Gastroenterology , vol.139
    • Seminowicz, D.A.1    Labus, J.S.2    Bueller, J.A.3
  • 20
    • 79955933357 scopus 로고    scopus 로고
    • White matter abnormalities in irritable bowel syndrome and relation to individual factors
    • Chen JY, Blankstein U, Diamant NE, et al : White matter abnormalities in irritable bowel syndrome and relation to individual factors. Brain Res 1392; 121-131 : 2011
    • (2011) Brain Res , vol.1392 , pp. 121-131
    • Chen, J.Y.1    Blankstein, U.2    Diamant, N.E.3
  • 21
    • 84880425146 scopus 로고    scopus 로고
    • Patients with chronic visceral pain show sex-related alterations in intrinsic oscillations of the resting brain
    • Hong JY, Kilpatrick LA, Labus J, et al : Patients with chronic visceral pain show sex-related alterations in intrinsic oscillations of the resting brain. J Neurosci 33; 11994-12002 : 2013
    • (2013) J Neurosci , vol.33 , pp. 11994-12002
    • Hong, J.Y.1    Kilpatrick, L.A.2    Labus, J.3
  • 22
    • 84884284142 scopus 로고    scopus 로고
    • Sex differences in emotion-related cognitive processes in irritable bowel syndrome and healthy control subjects
    • Labus JS, Gupta A, Coveleskie K, et al : Sex differences in emotion-related cognitive processes in irritable bowel syndrome and healthy control subjects. Pain 154; 2088-2099 : 2013
    • (2013) Pain , vol.154 , pp. 2088-2099
    • Labus, J.S.1    Gupta, A.2    Coveleskie, K.3
  • 23
    • 33645014144 scopus 로고    scopus 로고
    • Cognitive therapy for irritable bowel syndrome is associated with reduced limbic activity, GI symptoms, and anxiety
    • Lackner JM, Lou Coad M, Mertz HR, et al : Cognitive therapy for irritable bowel syndrome is associated with reduced limbic activity, GI symptoms, and anxiety. Behav Res Ther 44; 621-638 : 2006
    • (2006) Behav Res Ther , vol.44 , pp. 621-638
    • Lackner, J.M.1    Lou Coad, M.2    Mertz, H.R.3
  • 24
    • 17644384100 scopus 로고    scopus 로고
    • Amitriptyline reduces rectal pain related activation of the anterior cingulate cortex in patients with irritable bowel syndrome
    • Morgan V, Pickens D, Gautam S, et al : Amitriptyline reduces rectal pain related activation of the anterior cingulate cortex in patients with irritable bowel syndrome. Gut 54; 601-607 : 2005
    • (2005) Gut , vol.54 , pp. 601-607
    • Morgan, V.1    Pickens, D.2    Gautam, S.3
  • 25
    • 84877945670 scopus 로고    scopus 로고
    • Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome
    • Lowén MB, Mayer EA, Sjöberg M, et al : Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome. Aliment Pharmacol Ther 37; 1184-1197 : 2013
    • (2013) Aliment Pharmacol Ther , vol.37 , pp. 1184-1197
    • Lowén, M.B.1    Mayer, E.A.2    Sjöberg, M.3
  • 26
    • 84861200679 scopus 로고    scopus 로고
    • Enhanced affect/cognition-related brain responses during visceral placebo analgesia in irritable bowel syndrome patients
    • Lee HF, Hsieh JC, Lu CL, et al : Enhanced affect/cognition-related brain responses during visceral placebo analgesia in irritable bowel syndrome patients. Pain 153; 1301-1310 : 2012
    • (2012) Pain , vol.153 , pp. 1301-1310
    • Lee, H.F.1    Hsieh, J.C.2    Lu, C.L.3
  • 27
    • 1942446313 scopus 로고    scopus 로고
    • The neural correlates of placebo effects: A disruption account
    • Lieberman MD, Jarcho JM, Berman S, et al : The neural correlates of placebo effects : a disruption account. Neuroimage 22; 447-455 : 2004
    • (2004) Neuroimage , vol.22 , pp. 447-455
    • Lieberman, M.D.1    Jarcho, J.M.2    Berman, S.3
  • 28
    • 77953229894 scopus 로고    scopus 로고
    • A prefrontal non-opioid mechanism in placebo analgesia
    • Petrovic P, Kalso E, Petersson KM, et al : A prefrontal non-opioid mechanism in placebo analgesia. Pain 150; 59-65 : 2010
    • (2010) Pain , vol.150 , pp. 59-65
    • Petrovic, P.1    Kalso, E.2    Petersson, K.M.3
  • 29
    • 84868029961 scopus 로고    scopus 로고
    • Altered cognitive function of prefrontal cortex during error feedback in patients with irritable bowel syndrome, based on FMRI and dynamic causal modeling
    • Aizawa E, Sato Y, Kochiyama T, et al : Altered cognitive function of prefrontal cortex during error feedback in patients with irritable bowel syndrome, based on FMRI and dynamic causal modeling. Gastroenterology 143; 1188-1198 : 2012
    • (2012) Gastroenterology , vol.143 , pp. 1188-1198
    • Aizawa, E.1    Sato, Y.2    Kochiyama, T.3
  • 30
    • 84888235650 scopus 로고    scopus 로고
    • Impaired emotional learning and involvement of the corticotropin- releasing factor signaling system in patients with irritable bowel syndrome
    • Labus JS, Hubbard CS, Bueller J, et al : Impaired emotional learning and involvement of the corticotropin-releasing factor signaling system in patients with irritable bowel syndrome. Gastroenterology 145 ; 1253-1261.e1-e3 : 2013
    • (2013) Gastroenterology , vol.145
    • Labus, J.S.1    Hubbard, C.S.2    Bueller, J.3
  • 31
    • 84855354656 scopus 로고    scopus 로고
    • Neurokinin-1- receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: A pilot study
    • Tillisch K, Labus J, Nam B, et al : Neurokinin-1- receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome : a pilot study. Aliment Pharmacol Ther 35; 360-367 : 2012
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 360-367
    • Tillisch, K.1    Labus, J.2    Nam, B.3
  • 32
    • 0024436089 scopus 로고
    • Central nervous system action of TRH to influence gastrointestinal function and ulceration
    • Taché Y, Stephens RL Jr, Ishikawa T : Central nervous system action of TRH to influence gastrointestinal function and ulceration. Ann N Y Acad Sci 553; 269-285 : 1989
    • (1989) Ann N Y Acad Sci , vol.553 , pp. 269-285
    • Taché, Y.1    Stephens Jr., R.L.2    Ishikawa, T.3
  • 33
    • 33846000959 scopus 로고    scopus 로고
    • Corticotropin-releasing factor receptors and stress-related alterations of gut motor function
    • Taché Y, Bonaz B : Corticotropin-releasing factor receptors and stress-related alterations of gut motor function. J Clin Invest 117; 33-40 : 2007
    • (2007) J Clin Invest , vol.117 , pp. 33-40
    • Taché, Y.1    Bonaz, B.2
  • 34
    • 84888639246 scopus 로고    scopus 로고
    • Stress and visceral pain: Focusing on irritable bowel syndrome
    • Fukudo S : Stress and visceral pain : focusing on irritable bowel syndrome. Pain 154 (suppl 1); S63- S70 : 2013
    • (2013) Pain , vol.154 , Issue.SUPPL. 1
    • Fukudo, S.1
  • 35
    • 67650028335 scopus 로고    scopus 로고
    • Neuroendocrine control of the gut during stress: Corticotropin-releasing factor signaling pathways in the spotlight
    • Stengel A, Taché Y : Neuroendocrine control of the gut during stress : corticotropin-releasing factor signaling pathways in the spotlight. Annu Rev Physiol 71; 219-239 : 2009
    • (2009) Annu Rev Physiol , vol.71 , pp. 219-239
    • Stengel, A.1    Taché, Y.2
  • 36
    • 84872688004 scopus 로고    scopus 로고
    • Peripheral corticotropin-releasing factor (CRF) induces stimulation of gastric contractions in freely moving conscious rats: Role of CRF receptor types 1 and 2
    • Nozu T, Tsuchiya Y, Kumei S, et al : Peripheral corticotropin-releasing factor (CRF) induces stimulation of gastric contractions in freely moving conscious rats : role of CRF receptor types 1 and 2. Neurogastroenterol Motil 25; 190-197 : 2013
    • (2013) Neurogastroenterol Motil , vol.25 , pp. 190-197
    • Nozu, T.1    Tsuchiya, Y.2    Kumei, S.3
  • 37
    • 84901471016 scopus 로고    scopus 로고
    • Water-avoidance stress enhances gastric contractions in freely moving conscious rats: Role of peripheral CRF receptors
    • Nozu T, Kumei S, Takakusaki K, et al : Water-avoidance stress enhances gastric contractions in freely moving conscious rats : role of peripheral CRF receptors. J Gastroenterol 49; 799-805 : 2014
    • (2014) J Gastroenterol , vol.49 , pp. 799-805
    • Nozu, T.1    Kumei, S.2    Takakusaki, K.3
  • 38
    • 0024412884 scopus 로고
    • Interleukin-1 inhibits the secretion of gastric acid in rats: Possible involvement of prostaglandin
    • Uehara A, Okumura T, Sekiya C, et al : Interleukin-1 inhibits the secretion of gastric acid in rats : possible involvement of prostaglandin. Biochem Biophys Res Commun 162; 1578-1584 : 1989
    • (1989) Biochem Biophys Res Commun , vol.162 , pp. 1578-1584
    • Uehara, A.1    Okumura, T.2    Sekiya, C.3
  • 39
    • 0025323372 scopus 로고
    • Inhibition of gastric pepsin secretion by peripherally or centrally injected interleukin-1 in rats
    • Okumura T, Uehara A, Okamura K, et al : Inhibition of gastric pepsin secretion by peripherally or centrally injected interleukin-1 in rats. Biochem Biophys Res Commun 167; 956-961 : 1990
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 956-961
    • Okumura, T.1    Uehara, A.2    Okamura, K.3
  • 40
    • 0025689304 scopus 로고
    • Interleukin-1: A cytokine that has potent antisecretory and anti-ulcer actions via the central nervous system
    • Uehara A, Okumura T, Kitamori S, et al : Interleukin-1 : a cytokine that has potent antisecretory and anti-ulcer actions via the central nervous system. Biochem Biophys Res Commun 173; 585-590 : 1990
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 585-590
    • Uehara, A.1    Okumura, T.2    Kitamori, S.3
  • 41
    • 0025837903 scopus 로고
    • Central nervous system action of basic fibroblast growth factor: Inhibition of gastric acid and pepsin secretion
    • Okumura T, Uehara A, Tsuji K, et al : Central nervous system action of basic fibroblast growth factor : inhibition of gastric acid and pepsin secretion. Biochem Biophys Res Commun 175; 527- 531 : 1991
    • (1991) Biochem Biophys Res Commun , vol.175 , pp. 527-531
    • Okumura, T.1    Uehara, A.2    Tsuji, K.3
  • 42
    • 0025804892 scopus 로고
    • Prevention by interleukin-1 of intracisternally injected thyrotropin-releasing hormone (TRH)-induced gastric mucosal lesions in rats
    • Okumura T, Uehara A, Kitamori S, et al : Prevention by interleukin-1 of intracisternally injected thyrotropin-releasing hormone (TRH)-induced gastric mucosal lesions in rats. Neurosci Lett 125; 31-33 : 1991
    • (1991) Neurosci Lett , vol.125 , pp. 31-33
    • Okumura, T.1    Uehara, A.2    Kitamori, S.3
  • 43
    • 0025895488 scopus 로고
    • Central basic fibroblast growth factor inhibits gastric ulcer formation in rats
    • Okumura T, Uehara A, Kitamori S, et al : Central basic fibroblast growth factor inhibits gastric ulcer formation in rats. Biochem Biophys Res Commun 177; 809-813 : 1991
    • (1991) Biochem Biophys Res Commun , vol.177 , pp. 809-813
    • Okumura, T.1    Uehara, A.2    Kitamori, S.3
  • 44
    • 0026529601 scopus 로고
    • Basic fibroblast growth factor (bFGF) acts centrally in the brain to inhibit gastric emptying in rats
    • Okumura T, Uehara A, Kitamori S, et al : Basic fibroblast growth factor (bFGF) acts centrally in the brain to inhibit gastric emptying in rats. Neurosci Lett 137; 53-55 : 1992
    • (1992) Neurosci Lett , vol.137 , pp. 53-55
    • Okumura, T.1    Uehara, A.2    Kitamori, S.3
  • 45
    • 0028265528 scopus 로고
    • Sitespecific formation of thyrotropin-releasing hormone-induced gastric ulcers through the vagal system
    • Okumura T, Uehara A, Watanabe Y, et al : Sitespecific formation of thyrotropin-releasing hormone-induced gastric ulcers through the vagal system. Scand J Gastroenterol 29; 226-231 : 1994
    • (1994) Scand J Gastroenterol , vol.29 , pp. 226-231
    • Okumura, T.1    Uehara, A.2    Watanabe, Y.3
  • 46
    • 0028005373 scopus 로고
    • Stimulation of gastric secretion and enhanced gastric mucosal damage following central administration of pancreatic polypeptide (PP) in rats
    • Okumura T, Pappas TN, Taylor IL : Stimulation of gastric secretion and enhanced gastric mucosal damage following central administration of pancreatic polypeptide (PP) in rats. Dig Dis Sci 39; 2398-2406 : 1994
    • (1994) Dig Dis Sci , vol.39 , pp. 2398-2406
    • Okumura, T.1    Pappas, T.N.2    Taylor, I.L.3
  • 47
    • 0027936352 scopus 로고
    • Intracisternal injection of pancreatic polypeptide stimulates gastric emptying in rats
    • Okumura T, Pappas TN, Taylor IL : Intracisternal injection of pancreatic polypeptide stimulates gastric emptying in rats. Neurosci Lett 178; 167- 170 : 1994
    • (1994) Neurosci Lett , vol.178 , pp. 167-170
    • Okumura, T.1    Pappas, T.N.2    Taylor, I.L.3
  • 48
    • 0027996485 scopus 로고
    • Intracisternal injection of apolipoprotein A-IV inhibits gastric secretion in pylorus-ligated concious rats
    • Okumura T, Fukagawa K, Tso P, et al : Intracisternal injection of apolipoprotein A-IV inhibits gastric secretion in pylorus-ligated concious rats. Gastroenterology 107; 1861-1864 : 1994
    • (1994) Gastroenterology , vol.107 , pp. 1861-1864
    • Okumura, T.1    Fukagawa, K.2    Tso, P.3
  • 49
    • 0028964241 scopus 로고
    • Pancreatic polypeptide microinjection into the dorsal motor nucleus inhibits pancreatic secretion in rats
    • Okumura T, Pappas TN, Taylor IL : Pancreatic polypeptide microinjection into the dorsal motor nucleus inhibits pancreatic secretion in rats. Gastroenterology 108; 1517-1525 : 1995
    • (1995) Gastroenterology , vol.108 , pp. 1517-1525
    • Okumura, T.1    Pappas, T.N.2    Taylor, I.L.3
  • 50
    • 0028852898 scopus 로고
    • Microinjection of TRH analogue into the dorsal vagal complex simulates pancreatic secretion in rats
    • Okumura T, Taylor IL, Pappas TN : Microinjection of TRH analogue into the dorsal vagal complex simulates pancreatic secretion in rats. Am J Physiol 269; G328-G334 : 1995
    • (1995) Am J Physiol , vol.269
    • Okumura, T.1    Taylor, I.L.2    Pappas, T.N.3
  • 51
    • 0028835429 scopus 로고
    • Gastric mucosal damage induced by 2-deoxy-D-glucose involves medullary TRH in the rat
    • Okumura T, Grant AP, Taylor IL, et al : Gastric mucosal damage induced by 2-deoxy-D-glucose involves medullary TRH in the rat. Regul Pept 55; 311-319 : 1995
    • (1995) Regul Pept , vol.55 , pp. 311-319
    • Okumura, T.1    Grant, A.P.2    Taylor, I.L.3
  • 52
    • 0028930072 scopus 로고
    • Intracisternal injection of TRH antibody blocks gastric emptying stimulated by 2-deoxy-D-glucose in rats
    • Okumura T, Taylor IL, Ohning G, et al : Intracisternal injection of TRH antibody blocks gastric emptying stimulated by 2-deoxy-D-glucose in rats. Brain Res 674; 137-141 : 1995
    • (1995) Brain Res , vol.674 , pp. 137-141
    • Okumura, T.1    Taylor, I.L.2    Ohning, G.3
  • 53
    • 0028847837 scopus 로고
    • Apolipoprotein A-IV acts centrally in the brain to reduce the severity of gastric ulceration in the rat
    • Okumura T, Taylor IL, Fukagawa K, et al : Apolipoprotein A-IV acts centrally in the brain to reduce the severity of gastric ulceration in the rat. Brain Res 673; 153-156 : 1995
    • (1995) Brain Res , vol.673 , pp. 153-156
    • Okumura, T.1    Taylor, I.L.2    Fukagawa, K.3
  • 54
    • 0028849163 scopus 로고
    • Mechanism of action of intracisternal apolipoprotein AIV in inhibiting gastric acid secretion in rats
    • Okumura T, Fukagawa K, Tso P, et al : Mechanism of action of intracisternal apolipoprotein AIV in inhibiting gastric acid secretion in rats. Gastroenterology 109; 1583-1588 : 1995
    • (1995) Gastroenterology , vol.109 , pp. 1583-1588
    • Okumura, T.1    Fukagawa, K.2    Tso, P.3
  • 55
    • 0030065840 scopus 로고    scopus 로고
    • Apolipoprotein A-IV acts in the brain to inhibit gastric emptying in the rat
    • Okumura T, Fukagawa K, Tso P, et al : Apolipoprotein A-IV acts in the brain to inhibit gastric emptying in the rat. Am J Physiol 270; G49-G53 : 1996
    • (1996) Am J Physiol , vol.270
    • Okumura, T.1    Fukagawa, K.2    Tso, P.3
  • 56
    • 0034465866 scopus 로고    scopus 로고
    • Cocaine-amphetamine-regulated transcript (CART) acts in the central nervous system to inhibit gastric acid secretion via brain corticotropin- releasing factor system
    • Okumura T, Yamada H, Motomura W, et al : Cocaine-amphetamine-regulated transcript (CART) acts in the central nervous system to inhibit gastric acid secretion via brain corticotropin-releasing factor system. Endocrinology 141; 2854-2860 : 2000
    • (2000) Endocrinology , vol.141 , pp. 2854-2860
    • Okumura, T.1    Yamada, H.2    Motomura, W.3
  • 57
    • 0029774083 scopus 로고    scopus 로고
    • Role of selected peptides in the vagal regulation of gastric motor and endocrine pancreatic function
    • Krowicki ZK : Role of selected peptides in the vagal regulation of gastric motor and endocrine pancreatic function. J Physiol Pharmacol 47; 399- 409 : 1996
    • (1996) J Physiol Pharmacol , vol.47 , pp. 399-409
    • Krowicki, Z.K.1
  • 58
    • 0025807723 scopus 로고
    • Central and peripheral actions of calcitonin gene-related peptide on gastric secretory and motor function
    • Taché Y, Raybould H, Wei JY : Central and peripheral actions of calcitonin gene-related peptide on gastric secretory and motor function. Adv Exp Med Biol 298; 183-198 : 1991
    • (1991) Adv Exp Med Biol , vol.298 , pp. 183-198
    • Taché, Y.1    Raybould, H.2    Wei, J.Y.3
  • 59
    • 0025190418 scopus 로고
    • Central nervous system action of peptides to influence gastrointestinal motor function
    • Taché Y, Garrick T, Raybould H : Central nervous system action of peptides to influence gastrointestinal motor function. Gastroenterology 98; 517-528 : 1990
    • (1990) Gastroenterology , vol.98 , pp. 517-528
    • Taché, Y.1    Garrick, T.2    Raybould, H.3
  • 60
    • 0031776646 scopus 로고    scopus 로고
    • Central action of adrenomedullin to prevent ethanolinduced gastric injury through vagal pathways in rats
    • Kaneko H, Mitsuma T, Nagai H, et al : Central action of adrenomedullin to prevent ethanolinduced gastric injury through vagal pathways in rats. Am J Physiol 274; R1783-R1788 : 1998
    • (1998) Am J Physiol , vol.274
    • Kaneko, H.1    Mitsuma, T.2    Nagai, H.3
  • 61
    • 84879269515 scopus 로고    scopus 로고
    • Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone
    • Holmes GM, Browning KN, Babic T, et al : Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone. J Physiol 591; 3081- 3100 : 2013
    • (2013) J Physiol , vol.591 , pp. 3081-3100
    • Holmes, G.M.1    Browning, K.N.2    Babic, T.3
  • 62
    • 84865703218 scopus 로고    scopus 로고
    • Nesfatin-1 inhibits gastric acid secretion via a central vagal mechanism in rats
    • Xia ZF, Fritze DM, Li JY, et al : Nesfatin-1 inhibits gastric acid secretion via a central vagal mechanism in rats. Am J Physiol Gastrointest Liver Physiol 303; G570-G577 : 2012
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303
    • Xia, Z.F.1    Fritze, D.M.2    Li, J.Y.3
  • 63
    • 77957596611 scopus 로고    scopus 로고
    • Centrally administered nesfatin-1 inhibits feeding behaviour and gastroduodenal motility in mice
    • Atsuchi K, Asakawa A, Ushikai M, et al : Centrally administered nesfatin-1 inhibits feeding behaviour and gastroduodenal motility in mice. Neuroreport 21; 1008-1011 : 2010
    • (2010) Neuroreport , vol.21 , pp. 1008-1011
    • Atsuchi, K.1    Asakawa, A.2    Ushikai, M.3
  • 64
    • 70350319523 scopus 로고    scopus 로고
    • Central nesfatin-1 reduces dark-phase food intake and gastric emptying in rats: Differential role of corticotropin-releasing factor2 receptor
    • Stengel A, Goebel M, Wang L, et al : Central nesfatin-1 reduces dark-phase food intake and gastric emptying in rats : differential role of corticotropin-releasing factor2 receptor. Endocrinology 150; 4911-4919 : 2009
    • (2009) Endocrinology , vol.150 , pp. 4911-4919
    • Stengel, A.1    Goebel, M.2    Wang, L.3
  • 65
    • 0027317633 scopus 로고
    • Intracerebroventricular neuropeptide Y increases gastric and pancreatic secretion in the dog
    • Geoghegan JG, Lawson DC, Cheng CA, et al : Intracerebroventricular neuropeptide Y increases gastric and pancreatic secretion in the dog. Gastroenterology 105; 1069-1077 : 1993
    • (1993) Gastroenterology , vol.105 , pp. 1069-1077
    • Geoghegan, J.G.1    Lawson, D.C.2    Cheng, C.A.3
  • 66
    • 0028822015 scopus 로고
    • Central inhibitory action of peptide YY on gastric motility in rats
    • Chen CH, Rogers RC : Central inhibitory action of peptide YY on gastric motility in rats. Am J Physiol 269; R787-R792 : 1995
    • (1995) Am J Physiol , vol.269
    • Chen, C.H.1    Rogers, R.C.2
  • 67
    • 79953085432 scopus 로고    scopus 로고
    • Ghrelin family of peptides and gut motility
    • Asakawa A, Ataka K, Fujino K, et al : Ghrelin family of peptides and gut motility. J Gastroenterol Hepatol 26 (suppl 3); 73-74 : 2011
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.SUPPL. 3 , pp. 73-74
    • Asakawa, A.1    Ataka, K.2    Fujino, K.3
  • 68
    • 0034816726 scopus 로고    scopus 로고
    • Ghrelin acts in the central nervous system to stimulate gastric acid secretion
    • Date Y, Nakazato M, Murakami N, et al : Ghrelin acts in the central nervous system to stimulate gastric acid secretion. Biochem Biophys Res Commun 280; 904-907 : 2001
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 904-907
    • Date, Y.1    Nakazato, M.2    Murakami, N.3
  • 69
    • 0029782197 scopus 로고    scopus 로고
    • Pancreatic secretion evoked by cholecystokinin and non- cholecystokinindependent duodenal stimuli via vagal afferent fibres in the rat
    • Li Y, Owyang C : Pancreatic secretion evoked by cholecystokinin and non-cholecystokinindependent duodenal stimuli via vagal afferent fibres in the rat. J Physiol 494; 773-782 : 1996
    • (1996) J Physiol , vol.494 , pp. 773-782
    • Li, Y.1    Owyang, C.2
  • 70
    • 20244380014 scopus 로고    scopus 로고
    • Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • Sakurai T, Amemiya A, Ishii M, et al : Orexins and orexin receptors : a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92; 573-585 : 1998
    • (1998) Cell , vol.92 , pp. 573-585
    • Sakurai, T.1    Amemiya, A.2    Ishii, M.3
  • 71
    • 0008390266 scopus 로고    scopus 로고
    • The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
    • de Lecea L, Kilduff TS, Peyron C, et al : The hypocretins : hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A 95; 322-327 : 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 322-327
    • De Lecea, L.1    Kilduff, T.S.2    Peyron, C.3
  • 72
    • 0033608174 scopus 로고    scopus 로고
    • Stimulation of gastric acid secretion by centrally administered orexin-A in conscious rats
    • Takahashi N, Okumura T, Yamada H, et al : Stimulation of gastric acid secretion by centrally administered orexin-A in conscious rats. Biochem Biophys Res Commun 254; 623-627 : 1999
    • (1999) Biochem Biophys Res Commun , vol.254 , pp. 623-627
    • Takahashi, N.1    Okumura, T.2    Yamada, H.3
  • 73
    • 0034805305 scopus 로고    scopus 로고
    • Requirement of intact disulfide bonds in orexin-Ainduced stimulation of gastric acid secretion that is mediated by OX1 receptor activation
    • Okumura T, Takeuchi S, Motomura W, et al : Requirement of intact disulfide bonds in orexin-Ainduced stimulation of gastric acid secretion that is mediated by OX1 receptor activation. Biochem Biophys Res Commun 280; 976-981 : 2001
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 976-981
    • Okumura, T.1    Takeuchi, S.2    Motomura, W.3
  • 74
    • 84863093165 scopus 로고    scopus 로고
    • Endogenous orexin-A in the brain mediates 2-deoxy-D-glucose- induced stimulation of gastric motility in freely moving conscious rats
    • Nozu T, Tuchiya Y, Kumei S, et al : Endogenous orexin-A in the brain mediates 2-deoxy-D-glucose- induced stimulation of gastric motility in freely moving conscious rats. J Gastroenterol 47; 404-411 : 2012
    • (2012) J Gastroenterol , vol.47 , pp. 404-411
    • Nozu, T.1    Tuchiya, Y.2    Kumei, S.3
  • 75
    • 79958735203 scopus 로고    scopus 로고
    • Central orexin-A increases colonic motility in conscious rats
    • Nozu T, Kumei S, Takakusaki K, et al : Central orexin-A increases colonic motility in conscious rats. Neurosci Lett 498; 143-146 : 2011
    • (2011) Neurosci Lett , vol.498 , pp. 143-146
    • Nozu, T.1    Kumei, S.2    Takakusaki, K.3
  • 76
    • 0025097843 scopus 로고
    • Vagal motor neurons innervating the stomach are site-specifically organized in the dorsal motor nucleus of the vagus nerve in rats
    • Okumura T, Namiki M : Vagal motor neurons innervating the stomach are site-specifically organized in the dorsal motor nucleus of the vagus nerve in rats. J Auton Nerv Syst 29; 157-162 : 1990
    • (1990) J Auton Nerv Syst , vol.29 , pp. 157-162
    • Okumura, T.1    Namiki, M.2
  • 77
    • 0034684981 scopus 로고    scopus 로고
    • Inhibition of food intake by central injection of antiorexin antibody in fasted rats
    • Yamada H, Okumura T, Motomura W, et al : Inhibition of food intake by central injection of antiorexin antibody in fasted rats. Biochem Biophys Res Commun 267; 527-531 : 2000
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 527-531
    • Yamada, H.1    Okumura, T.2    Motomura, W.3
  • 78
    • 0035577786 scopus 로고    scopus 로고
    • Mechanisms of orexin-induced depolarizations in rat dorsal motor nucleus of vagus neurones in vitro
    • Hwang LL, Chen CT, Dun NJ : Mechanisms of orexin-induced depolarizations in rat dorsal motor nucleus of vagus neurones in vitro. J Physiol 537; 511-520 : 2001
    • (2001) J Physiol , vol.537 , pp. 511-520
    • Hwang, L.L.1    Chen, C.T.2    Dun, N.J.3
  • 80
    • 13444273346 scopus 로고    scopus 로고
    • A selective orexin-1 receptor antagonist, SB334867, blocks 2-DG-induced gastric acid secretion in rats
    • Yamada H, Takahashi N, Tanno S, et al : A selective orexin-1 receptor antagonist, SB334867, blocks 2-DG-induced gastric acid secretion in rats. Neurosci Lett 376; 137-142 : 2005
    • (2005) Neurosci Lett , vol.376 , pp. 137-142
    • Yamada, H.1    Takahashi, N.2    Tanno, S.3
  • 81
    • 0036830222 scopus 로고    scopus 로고
    • Central Orexin-A stimulates pancreatic exocrine secretion via the vagus
    • Miyasaka K, Masuda M, Kanai S, et al : Central Orexin-A stimulates pancreatic exocrine secretion via the vagus. Pancreas 25; 400-404 : 2002
    • (2002) Pancreas , vol.25 , pp. 400-404
    • Miyasaka, K.1    Masuda, M.2    Kanai, S.3
  • 82
    • 52749084662 scopus 로고    scopus 로고
    • Role of orexin in central regulation of gastrointestinal functions
    • Okumura T, Takakusaki K : Role of orexin in central regulation of gastrointestinal functions. J Gastroenterol 43; 652-660 : 2008
    • (2008) J Gastroenterol , vol.43 , pp. 652-660
    • Okumura, T.1    Takakusaki, K.2
  • 83
    • 34447539578 scopus 로고    scopus 로고
    • Intracisternal injection of orexin-A prevents ethanol-induced gastric mucosal damage in rats
    • Yamada H, Tanno S, Takakusaki K, et al : Intracisternal injection of orexin-A prevents ethanol-induced gastric mucosal damage in rats. J Gastroenterol 42; 336-341 : 2007
    • (2007) J Gastroenterol , vol.42 , pp. 336-341
    • Yamada, H.1    Tanno, S.2    Takakusaki, K.3
  • 84
    • 67649448978 scopus 로고    scopus 로고
    • Orexin/hypocretin: A neuropeptide at the interface of sleep, energy homeostasis, and reward system
    • Tsujino N, Sakurai T : Orexin/hypocretin : a neuropeptide at the interface of sleep, energy homeostasis, and reward system. Pharmacol Rev 61; 162-176 : 2009
    • (2009) Pharmacol Rev , vol.61 , pp. 162-176
    • Tsujino, N.1    Sakurai, T.2
  • 85
    • 27844592708 scopus 로고    scopus 로고
    • Orexinergic projections to the cat midbrain mediate alternation of emotional behavioural states from locomotion to cataplexy
    • Takakusaki K, Takahashi K, Saitoh K, et al : Orexinergic projections to the cat midbrain mediate alternation of emotional behavioural states from locomotion to cataplexy. J Physiol 568; 1003-1020 : 2005
    • (2005) J Physiol , vol.568 , pp. 1003-1020
    • Takakusaki, K.1    Takahashi, K.2    Saitoh, K.3
  • 86
    • 41149167542 scopus 로고    scopus 로고
    • Orexin signaling mediates the antidepressant-like effect of calorie restriction
    • Lutter M, Krishnan V, Russo SJ, et al : Orexin signaling mediates the antidepressant-like effect of calorie restriction. J Neurosci 28; 3071-3075 : 2008
    • (2008) J Neurosci , vol.28 , pp. 3071-3075
    • Lutter, M.1    Krishnan, V.2    Russo, S.J.3
  • 87
    • 56549106399 scopus 로고    scopus 로고
    • I.C.V. Administration of orexin-A induces an antidepressive-like effect through hippocampal cell proliferation
    • Ito N, Yabe T, Gamo Y, et al : I.c.v. administration of orexin-A induces an antidepressive-like effect through hippocampal cell proliferation. Neuroscience 157; 720-732 : 2008
    • (2008) Neuroscience , vol.157 , pp. 720-732
    • Ito, N.1    Yabe, T.2    Gamo, Y.3
  • 88
    • 34447531745 scopus 로고    scopus 로고
    • Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder
    • Brundin L, Björkqvist M, Petersén A, et al : Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder. Eur Neuropsychopharmacol 9; 573-579 : 2007
    • (2007) Eur Neuropsychopharmacol , vol.9 , pp. 573-579
    • Brundin, L.1    Björkqvist, M.2    Petersén, A.3
  • 89
    • 79953117998 scopus 로고    scopus 로고
    • Role of brain orexin in the pathophysiology of functional gastrointestinal disorders
    • Okumura T, Nozu T : Role of brain orexin in the pathophysiology of functional gastrointestinal disorders. J Gastroenterol Hepatol 26 (suppl 3); 61- 66 : 2011
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.SUPPL. 3 , pp. 61-66
    • Okumura, T.1    Nozu, T.2
  • 90
    • 65449165950 scopus 로고    scopus 로고
    • Postinfectious irritable bowel syndrome
    • Spiller R, Garsed K : Postinfectious irritable bowel syndrome. Gastroenterology 136; 1979-1988 : 2009
    • (2009) Gastroenterology , vol.136 , pp. 1979-1988
    • Spiller, R.1    Garsed, K.2
  • 91
    • 34547477105 scopus 로고    scopus 로고
    • Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome
    • Thabane M, Kottachchi DT, Marshall JK : Systematic review and meta-analysis : The incidence and prognosis of post-infectious irritable bowel syndrome. Aliment Pharmacol Ther 26; 535-544 : 2007
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 535-544
    • Thabane, M.1    Kottachchi, D.T.2    Marshall, J.K.3
  • 92
    • 79961219548 scopus 로고    scopus 로고
    • Inflammation-induced lethargy is mediated by suppression of orexin neuron activity
    • Grossberg AJ, Zhu X, Leinninger GM, et al : Inflammation-induced lethargy is mediated by suppression of orexin neuron activity. J Neurosci 31; 11376-11386 : 2011
    • (2011) J Neurosci , vol.31 , pp. 11376-11386
    • Grossberg, A.J.1    Zhu, X.2    Leinninger, G.M.3


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