Changes in the modulation of spinal pain processing are related to severity in irritable bowel syndrome

Neurogastroenterology and Motility

Volumn 25, Issue 7, 2013, Pages

  Bouhassira, D ^a,b   Moisset, X ^a   Jouet, P ^a,c,d   Duboc, H ^a,c,d   Coffin, B ^a,c,d   Sabate, J M ^a,c,d  

^a HÔPITAL AMBROISE PARÉ   (France)

^b LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^c HÔPITAL LOUIS MOURIER   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Diffuse Noxious Inhibitory Controls; Functional MRI; Irritable bowel syndrome; RIII reflex; Visceral pain

Indexed keywords

ADULT; ARTICLE; CATASTROPHIZING; CLINICAL ARTICLE; CLINICAL TRIAL; COLON DILATATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFUSE NOXIOUS INHIBITORY CONTROL; DISEASE SEVERITY; ELECTROENCEPHALOGRAM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IRRITABLE COLON; LEG; MOOD; NEUROMODULATION; NOCICEPTION; PRIORITY JOURNAL; SPINAL PAIN; SPINAL REFLEX; WATER IMMERSION;

ADULT; BRAIN; FEMALE; HUMANS; HYPERALGESIA; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IRRITABLE BOWEL SYNDROME; MAGNETIC RESONANCE IMAGING; MANOMETRY; PAIN; PAIN THRESHOLD; REFLEX; SPINAL CORD;

EID: 84879188207     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12123     Document Type: Article

References (51)

1. Spiller R, Aziz Q, Creed F et al. Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut 2007; 56: 1770-98.
2. Mertz H, Naliboff B, Munakata J, Niazi N, Mayer EA. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 1995; 109: 40-52.
3. Zhou Q, Verne GN. New insights into visceral hypersensitivity-clinical implications in IBS. Nat Rev Gastroenterol Hepatol 2011; 8: 349-55.
4. Wilder-Smith CH. The balancing act: endogenous modulation of pain in functional gastrointestinal disorders. Gut 2011; 60: 1589-99.
5. Coffin B, Bouhassira D, Sabate JM, Barbe L, Jian R. Alteration of the spinal modulation of nociceptive processing in patients with irritable bowel syndrome. Gut 2004; 53: 1465-70.
6. Sabate JM, Bouhassira D, Poupardin C et al. Sensory signalling effects of tegaserod in patients with irritable bowel syndrome with constipation. Neurogastroenterol Motil 2008; 20: 134-41.
7. Skljarevski V, Ramadan NM. The nociceptive flexion reflex in humans - review article. Pain 2002; 96: 3-8.
8. Le Bars D, Dickenson AH, Besson JM. Diffuse noxious inhibitory controls (DNIC). II: lack of effect on non-convergent neurones, supraspinal involvement and theoritical implications. Pain 1979; 6: 305-27.
9. Bouhassira D, Danziger N. Investigation of brainstem: descending pain modulation in animals and humans. Suppl Clin Neurophysiol 2006; 58: 134-49.
10. Coffin B, Farmachidi JP, Rueegg P, Bastie A, Bouhassira D. Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects. Aliment Pharmacol Ther 2003; 17: 577-85.
11. Berman S, Munakata J, Naliboff BD et al. Gender differences in regional brain response to visceral pressure in IBS patients. Eur J Pain 2000; 4: 157-72.
12. Mayer EA, Naliboff B, Lee O, Munakata J, Chang L. Review article: gender-related differences in functional gastrointestinal disorders. Aliment Pharmacol Ther 1999; 13 (Suppl. 2): 65-9.
13. Schmulson M, Lee OY, Chang L, Naliboff B, Mayer EA. Symptom differences in moderate to severe IBS patients based on predominant bowel habit. Am J Gastroenterol 1999; 94: 2929-35.
14. Longstreth GF, Thompson WG, Chey WD et al. Functional bowel disorders. Gastroenterology 2006; 130: 1480-91.
15. Francis CY, Morris J, Whorwell PJ. The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther 1997; 11: 395-402.
16. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361-70.
17. Sullivan M, Bishop S, Pivik J. The pain catastrophizing scale: development and validation. Psychol Assess 1995; 7: 432-524.
18. Bouhassira D, Danziger N, Attal N, Guirimand F. Comparison of the pain suppressive effects of clinical and experimental painful conditioning stimuli. Brain 2003; 126: 1068-78.
19. Moisset X, Bouhassira D, Denis D et al. Anatomical connections between brain areas activated during rectal distension in healthy volunteers: a visceral pain network. Eur J Pain 2010; 14: 142-8.
20. Piche M, Arsenault M, Poitras P, Rainville P, Bouin M. Widespread hypersensitivity is related to altered pain inhibition processes in irritable bowel syndrome. Pain 2010; 148: 49-58.
21. Wilder-Smith CH, Schindler D, Lovblad K, Redmond SM, Nirkko A. Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls. Gut 2004; 53: 1595-601.
22. Wilder-Smith CH, Robert-Yap J. Abnormal endogenous pain modulation and somatic and visceral hypersensitivity in female patients with irritable bowel syndrome. World J Gastroenterol 2007; 13: 3699-704.
23. Song GH, Venkatraman V, Ho KY et al. Cortical effects of anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients and healthy controls. Pain 2006; 126: 79-90.
24. Heymen S, Maixner W, Whitehead WE et al. Central processing of noxious somatic stimuli in patients with irritable bowel syndrome compared with healthy controls. Clin J Pain 2010; 26: 104-9.
25. Bouhassira D, Sabate JM, Coffin B et al. Effects of rectal distensions on nociceptive flexion reflexes in humans. Am J Physiol 1998; 275: G410-7.
26. Piche M, Bouin M, Arsenault M, Poitras P, Rainville P. Decreased pain inhibition in irritable bowel syndrome depends on altered descending modulation and higher-order brain processes. Neuroscience 2011; 195: 166-75.
27. Verne GN, Robinson ME, Vase L, Price DD. Reversal of visceral and cutaneous hyperalgesia by local rectal anesthesia in irritable bowel syndrome (IBS) patients. Pain 2003; 105: 223-30.
28. Price DD, Zhou Q, Moshiree B, Robinson ME, Nicholas VG. Peripheral and central contributions to hyperalgesia in irritable bowel syndrome. J Pain 2006; 7: 529-35.
29. Price DD, Craggs JG, Zhou Q et al. Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimaging. Neuroimage 2009; 47: 995-1001.
30. Bouin M, Meunier P, Riberdy-Poitras M, Poitras P. Pain hypersensitivity in patients with functional gastrointestinal disorders: a gastrointestinal-specific defect or a general systemic condition? Dig Dis Sci 2001; 46: 2542-8.
31. Zhou Q, Fillingim RB, Riley JL III, Malarkey WB, Verne GN. Central and peripheral hypersensitivity in the irritable bowel syndrome. Pain 2010; 148: 454-61.
32. Whitehead WE, Holtkotter B, Enck P et al. Tolerance for rectosigmoid distension in irritable bowel syndrome. Gastroenterology 1990; 98: 1187-92.
33. Accarino AM, Azpiroz F, Malagelada JR. Selective dysfunction of mechanosensitive intestinal afferents in irritable bowel syndrome. Gastroenterology 1995; 108: 636-43.
34. Verne GN, Robinson ME, Price DD. Hypersensitivity to visceral and cutaneous pain in the irritable bowel syndrome. Pain 2001; 93: 7-14.
35. Coffin B, Dapoigny M, Cloarec D, Comet D, Dyard F. Relationship between severity of symptoms and quality of life in 858 patients with irritable bowel syndrome. Gastroenterol Clin Biol 2004; 28: 11-5.
36. Drossman DA, Chang L, Bellamy N et al. Severity in irritable bowel syndrome: a Rome Foundation Working Team report. Am J Gastroenterol 2011; 106: 1749-59.
37. Azpiroz F, Bouin M, Camilleri M et al. Mechanisms of hypersensitivity in IBS and functional disorders. Neurogastroenterol Motil 2007; 19: 62-88.
38. Kuiken SD, Lindeboom R, Tytgat GN, Boeckxstaens GE. Relationship between symptoms and hypersensitivity to rectal distension in patients with irritable bowel syndrome. Aliment Pharmacol Ther 2005; 22: 157-64.
39. Poitras P, Riberdy PM, Plourde V, Boivin M, Verrier P. Evolution of visceral sensitivity in patients with irritable bowel syndrome. Dig Dis Sci 2002; 47: 914-20.
40. Sabate JM, Veyrac M, Mion F et al. Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome. Aliment Pharmacol Ther 2008; 28: 484-90.
41. Larsson MB, Tillisch K, Craig AD et al. Brain responses to visceral stimuli reflect visceral sensitivity thresholds in patients with irritable bowel syndrome. Gastroenterology 2012; 142: 463-72.
42. Posserud I, Syrous A, Lindstrom L et al. Altered rectal perception in irritable bowel syndrome is associated with symptom severity. Gastroenterology 2007; 133: 1113-23.
43. Rosenberger C, Elsenbruch S, Scholle A et al. Effects of psychological stress on the cerebral processing of visceral stimuli in healthy women. Neurogastroenterol Motil 2009; 21: e740-5.
44. Roy M, Piche M, Chen JI, Peretz I, Rainville P. Cerebral and spinal modulation of pain by emotions. Proc Natl Acad Sci USA 2009; 106: 20900-5.
45. Wiech K, Tracey I. The influence of negative emotions on pain: behavioral effects and neural mechanisms. Neuroimage 2009; 47: 987-94.
46. Piche M, Arsenault M, Rainville P. Cerebral and cerebrospinal processes underlying counterirritation analgesia. J Neurosci 2009; 29: 14236-46.
47. Derbyshire SW. A systematic review of neuroimaging data during visceral stimulation. Am J Gastroenterol 2003; 98: 12-20.
48. Derbyshire SW, Whalley MG, Stenger VA, Oakley DA. Cerebral activation during hypnotically induced and imagined pain. Neuroimage 2004; 23: 392-401.
49. Labus JS, Naliboff BD, Berman SM et al. Brain networks underlying perceptual habituation to repeated aversive visceral stimuli in patients with irritable bowel syndrome. Neuroimage 2009; 47: 952-60.
50. Tillisch K, Mayer EA, Labus JS. Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology 2011; 140: 91-100.
51. Elsenbruch S, Rosenberger C, Enck P et al. Affective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: an fMRI study. Gut 2010; 59: 489-95.