Polymer-cobalt(III) complexes: Structural analysis of metal chelates on DNA interaction and comparative cytotoxic activity

Journal of Biomolecular Structure and Dynamics

Volumn 32, Issue 11, 2014, Pages 1876-1888

  Nehru, Selvan ^a   Arunachalam, Sankaralingam ^a   Arun, Renganathan ^a   Premkumar, Kumpati ^a  

^a BHARATHIDASAN UNIVERSITY   (India)

Author keywords

branched polyethyleneimine; cytotoxicity; DNA binding; intercalation and electrostatic binding; polymer cobalt(III) complexes

Indexed keywords

ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG; [COBALT[DIPYRIDO[3,2 A:2',3' C](6,7,8,9 TETRAHYDRO)PHENAZINE] 2 (BRANCHED POLYETHYLENEIMINE)CHLORINE]CHLORINE; [COBALT[DIPYRIDO[3,2 D:2',3' F]QUINOXALINE] 2 (BRANCHED POLYETHYLENEIMINE)CHLORINE]CHLORINE; [COBALT[IMIDAZO[4,5 F]1,10 PHENANTHROLINE] 2 (BRANCHED POLYETHYLENEIMINE)CHLORINE]CHLORINE; CALF THYMUS DNA; CHELATING AGENT; COBALT; COORDINATION COMPOUND; DNA; INTERCALATING AGENT; PHENANTHROLINE DERIVATIVE; POLYETHYLENEIMINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER INHIBITION; CHELATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; IC 50; INTERCALATION COMPLEX; LIGAND BINDING; MCF 7 CELL LINE; MOLECULAR INTERACTION; PRIORITY JOURNAL; STATIC ELECTRICITY; STRUCTURE ANALYSIS; ANIMAL; BOVINE; CELL SURVIVAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; HEK293 CELL LINE; METABOLISM; STRUCTURE ACTIVITY RELATION;

ANIMALS; APOPTOSIS; CATTLE; CELL SURVIVAL; CHELATING AGENTS; COBALT; COORDINATION COMPLEXES; DNA; DNA FRAGMENTATION; HEK293 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTERCALATING AGENTS; MCF-7 CELLS; PHENANTHROLINES; POLYETHYLENEIMINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84905715374     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2013.836460     Document Type: Article

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