Peptidylarginine deiminases: Novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates

Journal of Neurochemistry

Volumn 130, Issue 4, 2014, Pages 555-562

  Lange, Sigrun ^a,b   Rocha Ferreira, Eridan ^a   Thei, Laura ^a   Mawjee, Priyanka ^a   Bennett, Kate ^a   Thompson, Paul R ^c   Subramanian, Venkataraman ^c   Nicholas, Anthony P ^d   Peebles, Donald ^e   Hristova, Mariya ^a   Raivich, Gennadij ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d University of Alabama at Birmingham   (United States)

^e ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

hypoxic ischaemic encephalopathy; lipopolysaccharide; microglia; neonatal; peptidylarginine deiminases; protein deimination citrullination

Indexed keywords

CL AMIDINE; ENZYME INHIBITOR; HISTONE H3; NEUROPROTECTIVE AGENT; PROTEIN ARGININE DEIMINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; CELL ACTIVATION; CELL DEATH; CELL LOSS; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; DRUG TARGETING; ENZYME INHIBITION; EXTERNAL CAPSULE; HIPPOCAMPUS; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MICROGLIA; MOUSE; NEUROLOGIC DISEASE; NEURONAL DAMAGE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEIMINATION; PROTEIN MODIFICATION; PYRIFORM CORTEX; SINGLE DRUG DOSE; SURVIVAL RATE; THALAMUS; TREATMENT OUTCOME;

HYPOXIC ISCHAEMIC ENCEPHALOPATHY; LIPOPOLYSACCHARIDE; MICROGLIA; NEONATAL; PEPTIDYLARGININE DEIMINASES; PROTEIN DEIMINATION/CITRULLINATION;

ANIMALS; ANIMALS, NEWBORN; BRAIN INFARCTION; CELL DEATH; CENTRAL NERVOUS SYSTEM BACTERIAL INFECTIONS; ENZYME INHIBITORS; HYDROLASES; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; ISOENZYMES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICROGLIA; NEURONS; ORNITHINE;

EID: 84905686982     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12744     Document Type: Article

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