Determinants of outcomes after head cooling for neonatal encephalopathy

Pediatrics

Volumn 119, Issue 5, 2007, Pages 912-921

  Wyatt, John S ^a   Gluckman, Peter D ^b   Liu, Ping Y ^c   Azzopardi, Denis ^d   Ballard, Roberta ^e   Edwards, A David ^d   Ferriero, Donna M ^f   Polin, Richard A ^g   Robertson, Charlene M ^h   Thoresen, Marianne ⁱ   Whitelaw, Andrew ⁱ   Gunn, Alistair J ^j  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c Drug and Device Development Company   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g Columbia University ^*  (United States)

^h UNIVERSITY OF ALBERTA   (Canada)

ⁱ UNIVERSITY OF BRISTOL   (United Kingdom)

^j UNIVERSITY OF AUCKLAND   (New Zealand)

more..

Author keywords

Birth weight; Hypoxic ischemic encephalopathy; Induced hypothermia; Neonatal encephalopathy; Pyrexia

Indexed keywords

APGAR SCORE; ARTICLE; BRAIN DISEASE; CLINICAL TRIAL; COLD TREATMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIVERY; DISABILITY SEVERITY; DISEASE SEVERITY; ELECTROENCEPHALOGRAM; FEMALE; FEVER; GESTATIONAL AGE; HEAD CIRCUMFERENCE; HUMAN; INDUCED HYPOTHERMIA; INFANT; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MULTICENTER STUDY; NERVE CELL DIFFERENTIATION; NEWBORN; NEWBORN DEATH; NEWBORN DISEASE; PARITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECTUM TEMPERATURE; SEIZURE; SEX DIFFERENCE; TREATMENT OUTCOME;

ELECTROENCEPHALOGRAPHY; FEMALE; HEAD; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; MALE;

EID: 34248209089     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2006-2839     Document Type: Article

References (46)

1. Gunn AJ. Cerebral hypothermia for prevention of brain injury following perinatal asphyxia. Curr Opin Pediatr. 2000;12:111-115
2. Vannucci RC, Perlman JM. Interventions for perinatal hypoxic-ischemic encephalopathy. Pediatrics. 1997;100:1004-1014
3. Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia to improve neurodevelopmental outcome following neonatal encephalopathy. Lancet. 2005;365:663-670
4. Gunn AJ, Gluckman PD, Wyatt JS, Thoresen M, Edwards AD. Selective head cooling after neonatal encephalopathy. Lancet. 2005;365:1619-1620
5. Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005;353:1574-1584
6. Eicher DJ, Wagner CL, Katikaneni LP, et al. Moderate hypothermia in neonatal encephalopathy: efficacy outcomes. Pediatr Neurol. 2005;32:11-17
7. Edwards AD, Azzopardi DV. Therapeutic hypothermia following perinatal asphyxia. Arch Dis Child Fetal Neonatal Ed. 2006;91:F127-F131
8. Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress: a clinical and electroencephalographic study. Arch Neurol. 1976;33:696-705
9. Thorngren-Jerneck K, Herbst A. Low 5-minute Apgar score: a population-based register study of 1 million term births. Obstet Gynecol. 2001;98:65-70
10. Badawi N, Kurinczuk JJ, Keogh JM, et al. Antepartum risk factors for newborn encephalopathy: the Western Australian case-control study. BMJ. 1998;317:1549-1553
11. al Naqeeb N, Edwards AD, Cowan FM, Azzopardi D. Assessment of neonatal encephalopathy by amplitude-integrated electroencephalography. Pediatrics. 1999;103:1263-1271
12. McBride MC, Laroia N, Guillet R. Electrographic seizures in neonates correlate with poor neurodevelopmental outcome. Neurology. 2000;55:506-513
13. Gunn AJ, Gluckman PD, Gunn TR. Selective head cooling in newborn infants after perinatal asphyxia: a safety study. Pediatrics. 1998;102:885-892
14. Battin MR, Dezoete JA, Gunn TR, Gluckman PD, Gunn AJ. Neurodevelopmental outcome of infants treated with head cooling and mild hypothermia after perinatal asphyxia. Pediatrics. 2001;107:480-484
15. Battin MR, Penrice J, Gunn TR, Gunn AJ. Treatment of term infants with head cooling and mild systemic hypothermia (35.0°C and 34.5°C) after perinatal asphyxia. Pediatrics. 2003;111:244-251
16. Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, Galuppi B. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol. 1997;39:214-223
17. Bayley N. Bayley Scales of Infant Development. 2nd ed. San Antonio, TX: Psychological Corp; 1993
18. National Center for Health Statistics. 2000 CDC growth charts: United States. Available at: www.cdc.gov/growthcharts. Accessed March 2, 2007
19. Perlman JM, Risser R. Can asphyxiated infants at risk for neonatal seizures be rapidly identified by current high-risk markers? Pediatrics. 1996;97:456-462
20. Robertson CM, Finer NN, Grace MG. School performance of survivors of neonatal encephalopathy associated with birth asphyxia at term. J Pediatr. 1989;114:753-760
21. Robertson CM. Long-term follow-up of term infants with perinatal asphyxia. In: Stevenson DK, Sunshine P, eds. Fetal and Neonatal Brain Injury. Cambridge, United Kingdom: Cambridge University Press; 2002:829-858
22. Miller SP, Latal B, Clark H, et al. Clinical signs predict 30-month neurodevelopmental outcome after neonatal encephalopathy. Am J Obstet Gynecol. 2004;190:93-99
23. Haaland K, Loberg EM, Steen PA, Thoresen M. Posthypoxic hypothermia in newborn piglets. Pediatr Res. 1997;41:505-512
24. Bona E, Hagberg H, Loberg EM, Bagenholm R, Thoresen M. Protective effects of moderate hypothermia after neonatal hypoxia-ischemia: short- and long-term outcome. Pediatr Res. 1998;43:738-745
25. Nedelcu J, Klein MA, Aguzzi A, Martin E. Resuscitative hypothermia protects the neonatal rat brain from hypoxic-ischemic injury. Brain Pathol. 2000;10:61-71
26. Geddes R, Vannucci RC, Vannucci SJ. Delayed cerebral atrophy following moderate hypoxia-ischemia in the immature rat. Dev Neurosci. 2001;23:180-185
27. Beilharz EJ, Williams CE, Dragunow M, Sirimanne ES, Gluckman PD. Mechanisms of delayed cell death following hypoxicischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss. Brain Res Mol Brain Res. 1995;29:1-14
28. O'Shea TM, Klinepeter KL, Dillard RG. Prenatal events and the risk of cerebral palsy in very low birth weight infants. Am J Epidemiol. 1998;147:362-369
29. Murphy DJ, Sellers S, Mackenzie IZ, Yudkin PL, Johnson AM. Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm singleton babies. Lancet. 1995;346:1449-1454
30. Zhao P, Zuo Z. Prenatal hypoxia-induced adaptation and neuroprotection that is inducible nitric oxide synthase-dependent. Neurobiol Dis. 2005;20:871-880
31. Gidday JM, Shah AR, Maceren RG, et al. Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning. J Cereb Blood Flow Metab. 1999;19:331-340
32. Gustavsson M, Anderson MF, Mallard C, Hagberg H. Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats. Pediatr Res. 2005;57:305-309
33. Baena RC, Busto R, Dietrich WD, Globus MY, Ginsberg MD. Hyperthermia delayed by 24 hours aggravates neuronal damage in rat hippocampus following global ischemia. Neurology. 1997;48:768-773
34. Shum-Tim D, Nagashima M, Shinoka T, et al. Postischemic hyperthermia exacerbates neurologic injury after deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 1998;116:780-792
35. Gunn AJ, Bennet L. Is temperature important in delivery room resuscitation? Semin Neonatol. 2001;6:241-249
36. Gunn AJ, Gunn TR. Effect of radiant heat on head temperature gradient in term infants. Arch Dis Child Fetal Neonatal Ed. 1996;74:F200-F203
37. Diringer MN. Treatment of fever in the neurologic intensive care unit with a catheter-based heat exchange system. Crit Care Med. 2004;32:559-564
38. Jordan KG. Status epilepticus: a perspective from the neuroscience intensive care unit. Neurosurg Clin N Am. 1994;5:671-686
39. Foster-Barber A, Dickens B, Ferriero DM. Human perinatal asphyxia: correlation of neonatal cytokines with MRI and outcome. Dev Neurosci. 2001;23:213-218
40. Martin-Ancel A, Garcia-Alix A, Pascual-Salcedo D, Cabanas F, Valcarce M, Quero J. Interleukin-6 in the cerebrospinal fluid after perinatal asphyxia is related to early and late neurological manifestations. Pediatrics. 1997;100:789-794
41. Gunn AJ, Thoresen M. Hypothermic neuroprotection. NeuroRx. 2006;3:154-169
42. Iwata S, Iwata O, Thornton JS, et al. Superficial brain is cooler in small piglets: neonatal hypothermia implications. Ann Neurol. 2006;60:578-585
43. Tooley JR, Satas S, Porter H, Silver IA, Thoresen M. Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective. Ann Neurol. 2003;53:65-72
44. Iwata O, Thornton JS, Sellwood MW, et al. Depth of delayed cooling alters neuroprotection pattern after hypoxia-ischemia. Ann Neurol. 2005;58:75-87
45. Rutherford MA, Azzopardi D, Whitelaw A, et al. Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy. Pediatrics. 2005;116:1001-1006
46. Niermeyer S, Kattwinkel J, Van Reempts P, et al. International Guidelines for Neonatal Resuscitation: an excerpt from the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Consensus on Science. Pediatrics. 2000;106(3). Available at: www.pediatrics.org/cgi/content/full/106/3/e29