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Volumn 9, Issue 1, 2014, Pages

Cysteine peptidases as schistosomiasis vaccines with inbuilt adjuvanticity

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PEROXIREDOXIN; SCHISTOSOMA VACCINE;

EID: 84905672787     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085401     Document Type: Article
Times cited : (54)

References (58)
  • 1
    • 74149087972 scopus 로고    scopus 로고
    • Parasites and poverty: The case of schistosomiasis
    • King CH (2010) Parasites and poverty: the case of schistosomiasis. Acta Trop 113: 95-104.
    • (2010) Acta Trop , vol.113 , pp. 95-104
    • King, C.H.1
  • 3
    • 84871099014 scopus 로고    scopus 로고
    • Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, et al. (2012) Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380: 2197-2223.
    • (2012) Lancet , vol.380 , pp. 2197-2223
    • Murray, C.J.1    Vos, T.2    Lozano, R.3    Naghavi, M.4    Flaxman, A.D.5
  • 4
    • 0016182510 scopus 로고
    • Schistosoma mansoni: Cercaria to schistosomule
    • Stirewalt MA (1974) Schistosoma mansoni: cercaria to schistosomule. Adv Parasitol 12:115-182.
    • (1974) Adv Parasitol , vol.12 , pp. 115-182
    • Stirewalt, M.A.1
  • 5
    • 80054685766 scopus 로고    scopus 로고
    • Insights into the functional biology of schistosomes
    • Walker AJ (2011) Insights into the functional biology of schistosomes. Parasit Vectors 4: 203.
    • (2011) Parasit Vectors , vol.4 , pp. 203
    • Walker, A.J.1
  • 7
    • 70549104806 scopus 로고    scopus 로고
    • Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome
    • Bos DH, Mayfield C, Minchella DJ (2009) Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome. BMC Genomics 10: 488.
    • (2009) BMC Genomics , vol.10 , pp. 488
    • Bos, D.H.1    Mayfield, C.2    Minchella, D.J.3
  • 9
    • 0036091894 scopus 로고    scopus 로고
    • Comparative efficacy of the Schistosoma mansoni nucleic acid vaccine, Sm23, following microseeding or gene gun delivery
    • DOI 10.1046/j.1365-3024.2002.00453.x
    • Da'dara AA, Skelly PJ, Fatakdawala M, Visovatti S, Eriksson E, et al. (2002) Comparative efficacy of the Schistosoma mansoni nucleic acid vaccine, Sm23, following microseeding or gene gun delivery. Parasite Immunol 24: 179-187. (Pubitemid 34534239)
    • (2002) Parasite Immunology , vol.24 , Issue.4 , pp. 179-187
    • Da'dara, A.A.1    Skelly, P.J.2    Fatakdawala, M.3    Visovatti, S.4    Eriksson, E.5    Harn, D.A.6
  • 11
    • 77649209926 scopus 로고    scopus 로고
    • Schistosoma mansoni Stomatin like protein-2 is located in the tegument and induces partial protection against challenge infection
    • Farias LP, Cardoso FC, Miyasato PA, Montoya BO, Tararam CA, et al. (2010) Schistosoma mansoni Stomatin like protein-2 is located in the tegument and induces partial protection against challenge infection. PLoS Negl Trop Dis 4: e597.
    • (2010) PLoS Negl Trop Dis , vol.4
    • Farias, L.P.1    Cardoso, F.C.2    Miyasato, P.A.3    Montoya, B.O.4    Tararam, C.A.5
  • 12
    • 38549179418 scopus 로고    scopus 로고
    • Current status of vaccines for schistosomiasis
    • DOI 10.1128/CMR.00046-07
    • McManus DP, Loukas A (2008) Current status of vaccines for schistosomiasis. Clin Microbiol Rev 21: 225-242. (Pubitemid 351160017)
    • (2008) Clinical Microbiology Reviews , vol.21 , Issue.1 , pp. 225-242
    • McManus, D.P.1    Loukas, A.2
  • 14
    • 77956269056 scopus 로고    scopus 로고
    • Innate immunogenicity and the in vitro protective potential of Schistosoma mansoni lung schistosomula excretory-secretory candidate vaccine antigens
    • El Ridi R, Tallima H, Mahana N, Dalton JP (2010) Innate immunogenicity and the in vitro protective potential of Schistosoma mansoni lung schistosomula excretory-secretory candidate vaccine antigens. Microbes Infect 12: 700-709.
    • (2010) Microbes Infect , vol.12 , pp. 700-709
    • El Ridi, R.1    Tallima, H.2    Mahana, N.3    Dalton, J.P.4
  • 16
    • 84876704528 scopus 로고    scopus 로고
    • Vaccine-induced protection against murine schistosomiasis mansoni with larval excretory-secretory antigens and papain or type-2 cytokines
    • El Ridi R, Tallima H (2013) Vaccine-induced protection against murine schistosomiasis mansoni with larval excretory-secretory antigens and papain or type-2 cytokines. J Parasitol 99: 194-202.
    • (2013) J Parasitol , vol.99 , pp. 194-202
    • El Ridi, R.1    Tallima, H.2
  • 18
    • 77953812779 scopus 로고    scopus 로고
    • The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling
    • Tang H, Cao W, Kasturi SP, Ravindran R, Nakaya HI, et al. (2010) The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat Immunol 11: 608-617.
    • (2010) Nat Immunol , vol.11 , pp. 608-617
    • Tang, H.1    Cao, W.2    Kasturi, S.P.3    Ravindran, R.4    Nakaya, H.I.5
  • 19
    • 84860481057 scopus 로고    scopus 로고
    • Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity
    • Liang G, Barker T, Xie Z, Charles N, Rivera J, et al. (2012) Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity. J Allergy Clin Immunol 129: 1377-1386.
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 1377-1386
    • Liang, G.1    Barker, T.2    Xie, Z.3    Charles, N.4    Rivera, J.5
  • 21
    • 0024261490 scopus 로고
    • Schistosoma mansoni: Expression and role of cysteine proteinases in developing schistosomula
    • DOI 10.1016/0014-4894(88)90071-9
    • Zerda KS, Dresden MH, Chappell CL (1988) Schistosoma mansoni: expression and role of cysteine proteinases in developing schistosomula. Exp Parasitol 67: 238-246. (Pubitemid 19008832)
    • (1988) Experimental Parasitology , vol.67 , Issue.2 , pp. 238-246
    • Zerda, K.S.1    Dresden, M.H.2    Chappell, C.L.3
  • 22
    • 0031060616 scopus 로고    scopus 로고
    • Schistosoma japonicum, S. mansoni, S. haematobium, S. intercalatum, and S. rodhaini: Cysteine-class cathepsin activities in the vomitus of adult worms
    • Caffrey CR, Rheinberg CE, Moné H, Jourdane J, Li YL, et al. (1997) Schistosoma japonicum, S. mansoni, S. haematobium, S. intercalatum, and S. rodhaini: cysteine-class cathepsin activities in the vomitus of adult worms. Parasitol Res 83: 37-41.
    • (1997) Parasitol Res , vol.83 , pp. 37-41
    • Caffrey, C.R.1    Rheinberg, C.E.2    Moné, H.3    Jourdane, J.4    Li, Y.L.5
  • 23
    • 0032945715 scopus 로고    scopus 로고
    • Recombinant expression and localization of Schistosoma mansoni cathepsin L1 support its role in the degradation of host hemoglobin
    • Brady CP, Dowd AJ, Brindley PJ, Ryan T, Day SR, et al. (1999) Recombinant expression and localization of Schistosoma mansoni cathepsin L1 support its role in the degradation of host hemoglobin. Infect Immun 67: 368-374. (Pubitemid 29021671)
    • (1999) Infection and Immunity , vol.67 , Issue.1 , pp. 368-374
    • Brady, C.P.1    Dowd, A.J.2    Brindley, P.J.3    Ryan, T.4    Day, S.R.5    Dalton, J.P.6
  • 25
    • 0034783828 scopus 로고    scopus 로고
    • Schistosoma mansoni proteases Sm31 (cathepsin B) and Sm32 (legumain) are expressed in the cecum and protonephridia of cercariae
    • Skelly PJ, Shoemaker CB (2001) Schistosoma mansoni proteases Sm31 (cathepsin B) and Sm32 (legumain) are expressed in the cecum and protonephridia of cercariae. J Parasitol 87: 1218-1221. (Pubitemid 32995694)
    • (2001) Journal of Parasitology , vol.87 , Issue.5 , pp. 1218-1221
    • Skelly, P.J.1    Shoemaker, C.B.2
  • 28
    • 24344439336 scopus 로고    scopus 로고
    • De-glycosylation of Pichia pastoris-produced Schistosoma mansoni cathepsin B eliminates non-specific reactivity with IgG in normal human serum
    • DOI 10.1016/j.jim.2005.07.019, PII S0022175905002449
    • Stack CM, Dalton JP, Cunneen M, Donnelly S (2005) De-glycosylation of Pichia pastoris - produced Schistosoma mansoni cathepsin B eliminates non-specific reactivity with IgG in normal human serum. J Immunol Meth 304: 151-157. (Pubitemid 41262229)
    • (2005) Journal of Immunological Methods , vol.304 , Issue.1-2 , pp. 151-157
    • Stack, C.M.1    Dalton, J.P.2    Cunneen, M.3    Donnelly, S.4
  • 29
    • 0033993673 scopus 로고    scopus 로고
    • Schistosoma mansoni: Differential expression of cathepsins L1 and L2 suggests discrete biological functions for each enzyme
    • DOI 10.1006/expr.1999.4478
    • Brady CP, Brindley PJ, Dowd A J, Dalton JP (2000) Schistosoma mansoni: differential expression of cathepsins L1 and L2 suggests discrete biological functions for each enzyme. Exp Parasitol 94: 75-83. (Pubitemid 30124105)
    • (2000) Experimental Parasitology , vol.94 , Issue.2 , pp. 75-83
    • Brady, C.P.1    Brindley, P.J.2    Dowd, A.J.3    Dalton, J.P.4
  • 31
    • 44349174988 scopus 로고    scopus 로고
    • Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica
    • Stack CM, Caffrey CR, Donnelly SM, Seshaadri A, Lowther J, et al. (2008) Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J Biol Chem 283: 9896-9908.
    • (2008) J Biol Chem , vol.283 , pp. 9896-9908
    • Stack, C.M.1    Caffrey, C.R.2    Donnelly, S.M.3    Seshaadri, A.4    Lowther, J.5
  • 33
    • 0035164572 scopus 로고    scopus 로고
    • Human T- and B-cell responses to Schistosoma mansoni recombinant glyceraldehyde 3-phosphate dehydrogenase correlate with resistance to reinfection with S. mansoni or Schistosoma haematobium after chemotherapy
    • DOI 10.1128/IAI.69.1.237-244.2001
    • El Ridi R, Shoemaker CB, Farouk F, El Sherif NH, Afifi A et al. (2001) Human T- and B-cell responses to Schistosoma mansoni recombinant glyceraldehyde 3-phosphate dehydrogenase correlate with resistance to reinfection with S. mansoni or Schistosoma haematobium after chemotherapy. Infect Immun 69: 237-244. (Pubitemid 32040948)
    • (2001) Infection and Immunity , vol.69 , Issue.1 , pp. 237-244
    • El, R.R.1    Shoemaker, C.B.2    Farouk, F.3    El, S.N.H.4    Afifi, A.5
  • 34
    • 55549093092 scopus 로고    scopus 로고
    • Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages
    • Donnelly S, Stack CM, O'Neill SM, Sayed AA, Williams DL, et al. (2008) Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J 22: 4022-4032.
    • (2008) FASEB J , vol.22 , pp. 4022-4032
    • Donnelly, S.1    Stack, C.M.2    O'Neill, S.M.3    Sayed, A.A.4    Williams, D.L.5
  • 35
    • 0027412489 scopus 로고
    • Identification of Schistosoma haematobium soluble egg antigens that elicit human granuloma formation in vitro
    • Gaafar T, Ismail S, Helmy M, Afifi A, Guirguis N, et al. (1993) Identification of Schistosoma haematobium soluble egg antigens that elicit human granuloma formation in vitro. Parasitol Res 79: 103-108. (Pubitemid 23072158)
    • (1993) Parasitology Research , vol.79 , Issue.2 , pp. 103-108
    • Gaafar, T.1    Ismail, S.2    Helmy, M.3    Afifi, A.4    Guirguis, N.5    El, R.R.6
  • 36
    • 0345283313 scopus 로고    scopus 로고
    • Incubation of Schistosoma mansoni lung-stage schistosomula in corn oil exposes their surface membrane antigenic specificities
    • El Ridi R, Mohamed SH, Tallima H (2003) Incubation of Schistosoma mansoni lung-stage schistosomula in corn oil exposes their surface membrane antigenic specificities. J Parasitol 89: 1064-1967.
    • (2003) J Parasitol , vol.89 , pp. 1064-1967
    • El Ridi, R.1    Mohamed, S.H.2    Tallima, H.3
  • 37
    • 0038543267 scopus 로고    scopus 로고
    • Differences in immunogenicity and vaccine potential of peptides from Schistosoma mansoni glyceraldehyde 3-phosphate dehydrogenase
    • Tallima H, Montash M, Veprek P, Velek J, Jezek J, et al. (2003) Differences in immunogenicity and vaccine potential of peptides from Schistosoma mansoni glyceraldehyde 3-phosphate dehydrogenase. Vaccine 21: 3290-4300.
    • (2003) Vaccine , vol.21 , pp. 3290-4300
    • Tallima, H.1    Montash, M.2    Veprek, P.3    Velek, J.4    Jezek, J.5
  • 39
    • 39449133957 scopus 로고    scopus 로고
    • A mechanism for the initiation of allergen-induced T helper type 2 responses
    • DOI 10.1038/ni1558, PII NI1558
    • Sokol CL, Barton GM, Farr AG, Medzhitov R (2008) A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol 9: 310-318. (Pubitemid 351267328)
    • (2008) Nature Immunology , vol.9 , Issue.3 , pp. 310-318
    • Sokol, C.L.1    Barton, G.M.2    Farr, A.G.3    Medzhitov, R.4
  • 40
    • 67649216604 scopus 로고    scopus 로고
    • Basophils function as antigen presenting cells for an allergen-induced T helper type 2 response
    • Sokol CL, Chu NQ, Yu S, Nish SA, Laufer TM, et al. (2009) Basophils function as antigen presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 10:713-720.
    • (2009) Nat Immunol , vol.10 , pp. 713-720
    • Sokol, C.L.1    Chu, N.Q.2    Yu, S.3    Nish, S.A.4    Laufer, T.M.5
  • 41
    • 77249166498 scopus 로고    scopus 로고
    • Role of basophils in the initiation of Th2 responses
    • Sokol CL, Medzhitov R (2010) Role of basophils in the initiation of Th2 responses. Curr Opin Immunol 22: 73-77.
    • (2010) Curr Opin Immunol , vol.22 , pp. 73-77
    • Sokol, C.L.1    Medzhitov, R.2
  • 42
    • 0021347246 scopus 로고
    • Autoradiographic analysis of resistance to reinfection with Schistosoma mansoni in mice. Evidence that the liver is a major site of worm elimination
    • Dean DA, Mangold BL (1984) Autoradiographic analysis of resistance to reinfection with Schistosoma mansoni in mice. Evidence that the liver is a major site of worm elimination. Am J Trop Med Hyg 33: 97-103. (Pubitemid 14190448)
    • (1984) American Journal of Tropical Medicine and Hygiene , vol.33 , Issue.1 , pp. 97-103
    • Dean, D.A.1    Mangold, B.L.2
  • 43
    • 0035834440 scopus 로고    scopus 로고
    • Modulation of blood fluke development in the liver by hepatic CD4 + lymphocytes
    • DOI 10.1126/science.1064462
    • Davies SJ, Grogan JL, Blank RB, Lim KC, Locksley RM, et al. (2001) Modulation of blood fluke development in the liver by hepatic CD4+ lymphocytes. Science 294: 1358-1361. (Pubitemid 33063105)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1358-1361
    • Davies, S.J.1    Grogan, J.L.2    Blank, R.B.3    Lim, K.C.4    Locksley, R.M.5    McKerrow, J.H.6
  • 44
    • 0026060650 scopus 로고
    • Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni
    • Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A (1991) Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med 173: 159-166.
    • (1991) J Exp Med , vol.173 , pp. 159-166
    • Pearce, E.J.1    Caspar, P.2    Grzych, J.M.3    Lewis, F.A.4    Sher, A.5
  • 46
    • 78149418680 scopus 로고    scopus 로고
    • Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection
    • de Oliveira Fraga LA, Lamb EW, Moreno EC, Chatterjee M, Dvoøák J, et al. (2010) Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection. BMC Immunol 11: 56.
    • (2010) BMC Immunol , vol.11 , pp. 56
    • De Oliveira Fraga, L.A.1    Lamb, E.W.2    Moreno, E.C.3    Chatterjee, M.4    Dvoøák, J.5
  • 47
    • 0020631567 scopus 로고
    • Schistosoma and related genera: Acquired resistance in mice
    • Dean DA (1983) Schistosoma and related genera: acquired resistance in mice. Exp Parasitol 55: 1-104.
    • (1983) Exp Parasitol , vol.55 , pp. 1-104
    • Dean, D.A.1
  • 48
    • 0032696176 scopus 로고    scopus 로고
    • Immune deviation as a strategy for schistosomiasis vaccines designed to prevent infection and egg-induced immunopathology
    • Wynn TA (1999) Immune deviation as a strategy for schistosomiasis vaccines designed to prevent infection and egg-induced immunopathology. Microbes Infect 1: 525-534.
    • (1999) Microbes Infect , vol.1 , pp. 525-534
    • Wynn, T.A.1
  • 49
    • 66149095461 scopus 로고    scopus 로고
    • Schistosoma japonicum chimeric protein with a novel adjuvant induced a polarized Th1 immune response and protection against liver egg burdens
    • Xu X, Zhang D, Sun W, Zhang Q, Zhang J, et al. (2009) Schistosoma japonicum chimeric protein with a novel adjuvant induced a polarized Th1 immune response and protection against liver egg burdens. BMC Infect Dis 9: 54.
    • (2009) BMC Infect Dis , vol.9 , pp. 54
    • Xu, X.1    Zhang, D.2    Sun, W.3    Zhang, Q.4    Zhang, J.5
  • 50
    • 0030919865 scopus 로고    scopus 로고
    • Immunization of mice with ultraviolet-attenuated cercariae of Schistosoma mansoni transiently reduces the fecundity of challenge worms
    • DOI 10.1016/S0020-7519(97)00006-4
    • El Ridi R, Ozaki T, Sato H, Inaba T, Kamiya H (1997) Immunization of mice with ultraviolet-attenuated cercariae of Schistosoma mansoni transiently reduces the fecundity of challenge worms. Int J Parasitol 27: 581-586. (Pubitemid 27278188)
    • (1997) International Journal for Parasitology , vol.27 , Issue.5 , pp. 581-586
    • El, R.R.1    Ozaki, T.2    Sato, H.3    Inaba, T.4    Kamiya, H.5
  • 51
    • 0029880287 scopus 로고    scopus 로고
    • Characterization of the cathepsin-like cysteine proteinases of Schistosoma mansoni
    • Dalton JP, Clough KA, Jones MK, Brindley PJ (1996) Characterization of the cathepsin-like cysteine proteinases of Schistosoma mansoni. Infect Immun 64: 1328-1334. (Pubitemid 26102397)
    • (1996) Infection and Immunity , vol.64 , Issue.4 , pp. 1328-1334
    • Dalton, J.P.1    Clough, K.A.2    Jones, M.K.3    Brindley, P.J.4
  • 52
    • 33846697738 scopus 로고    scopus 로고
    • Schistosomiasis mansoni: Novel chemotherapy using a cysteine protease inhibitor
    • Abdulla MH, Lim KC, Sajid M, McKerrow JH, Caffrey CR (2007) Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor. PLoS Med 4: e14.
    • (2007) PLoS Med , vol.4
    • Abdulla, M.H.1    Lim, K.C.2    Sajid, M.3    McKerrow, J.H.4    Caffrey, C.R.5
  • 53
    • 0023700715 scopus 로고
    • The hypersensitivity response to the adult worm proteinase, SMw32, in Schistosoma mansoni infected mice
    • Chappell CL, Kalter DC, Dresden MH (1988) The hypersensitivity response to the adult worm proteinase, SMw32, in Schistosoma mansoni infected mice. Am J Trop Med Hyg 39: 463-468.
    • (1988) Am J Trop Med Hyg , vol.39 , pp. 463-468
    • Chappell, C.L.1    Kalter, D.C.2    Dresden, M.H.3
  • 55
    • 33645510633 scopus 로고    scopus 로고
    • Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans
    • Ganley-Leal LM, Mwinzi PN, Cetre-Sossah CB, Andove J, Hightower AW, et al. (2006) Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans. Infect Immun 74: 2169-2176.
    • (2006) Infect Immun , vol.74 , pp. 2169-2176
    • Ganley-Leal, L.M.1    Mwinzi, P.N.2    Cetre-Sossah, C.B.3    Andove, J.4    Hightower, A.W.5
  • 56
    • 65449174926 scopus 로고    scopus 로고
    • Immunoglobulin E (IgE) responses to paramyosin predict resistance to reinfection with Schistosoma japonicum and are attenuated by IgG4
    • Jiz M, Friedman JF, Leenstra T, Jarilla B, Pablo A, et al. (2009) Immunoglobulin E (IgE) responses to paramyosin predict resistance to reinfection with Schistosoma japonicum and are attenuated by IgG4. Infect Immun 77: 2051-2058.
    • (2009) Infect Immun , vol.77 , pp. 2051-2058
    • Jiz, M.1    Friedman, J.F.2    Leenstra, T.3    Jarilla, B.4    Pablo, A.5
  • 57
    • 84870201357 scopus 로고    scopus 로고
    • Adult worm-specific IgE/IgG4 balance is associated with low infection levels of Schistosoma mansoni in an endemic area
    • Figueiredo JP, Oliveira RR, Cardoso LS, Barnes KC, Grant AV, et al. (2012) Adult worm-specific IgE/IgG4 balance is associated with low infection levels of Schistosoma mansoni in an endemic area. Parasite Immunol 34: 604-610.
    • (2012) Parasite Immunol , vol.34 , pp. 604-610
    • Figueiredo, J.P.1    Oliveira, R.R.2    Cardoso, L.S.3    Barnes, K.C.4    Grant, A.V.5
  • 58
    • 84870824134 scopus 로고    scopus 로고
    • Progressive cross-reactivity in IgE responses: An explanation for the slow development of human immunity to schistosomiasis?
    • Fitzsimmons CM, Jones FM, Pinot de Moira A, Protasio AV, Khalife J, et al. (2012) Progressive cross-reactivity in IgE responses: an explanation for the slow development of human immunity to schistosomiasis? Infect Immun 80: 4264-4270.
    • (2012) Infect Immun , vol.80 , pp. 4264-4270
    • Fitzsimmons, C.M.1    Jones, F.M.2    Pinot De Moira, A.3    Protasio, A.V.4    Khalife, J.5


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