Use of cytochrome P450-specific parameters and human biomarker data to develop a human physiologically based pharmacokinetic/pharmacodynamic model for dermal chlorpyrifos exposure

ACS Symposium Series

Volumn 1099, Issue , 2012, Pages 309-322

  Ellison, Corie A ^a   Knaak, James B ^a   McDougall, Robin ^b   Olson, James R ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF ONTARIO INSTITUTE OF TECHNOLOGY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; BLOOD; COMPUTATIONAL CHEMISTRY; PESTICIDES; PHYSIOLOGY; RATE CONSTANTS; RISK ASSESSMENT;

ACETYLCHOLINESTERASE ACTIVITY; BUTYRYLCHOLINESTERASE; CHOLINESTERASE ACTIVITY; CHOLINESTERASE INHIBITION; INACTIVE METABOLITES; KINETIC RATE CONSTANTS; OCCUPATIONAL EXPOSURE; ORGANOPHOS-PHORUS PESTICIDES;

PHYSIOLOGICAL MODELS;

EID: 84905654568     PISSN: 00976156     EISSN: 19475918     Source Type: Book Series    
DOI: 10.1021/bk-2012-1099.ch019     Document Type: Conference Paper

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