Association between length of gestation and cervical DNA methylation of PTGER2 and LINE 1-HS

Epigenetics

Volumn 9, Issue 8, 2014, Pages 1083-1091

  Burris, Heather H ^a   Baccarelli, Andrea A ^b   Motta, Valeria ^b,c   Byun, Hyang Min ^b   Just, Allan C ^b   Mercado Garcia, Adriana ^d   Schwartz, Joel ^b   Svensson, Katherine ^e   Téllez Rojo, Martha M ^d   Wright, Robert O ^e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cervix; DNA methylation; Epigenetics; LINE 1; Preterm birth; PTGER2

Indexed keywords

PROSTAGLANDIN E RECEPTOR 2; PTGER2 PROTEIN, HUMAN;

ADULT; COHORT ANALYSIS; DNA METHYLATION; FEMALE; GENETIC ASSOCIATION STUDY; GENETICS; HUMAN; LONG INTERSPERSED REPEAT; METABOLISM; PHYSIOLOGY; PREGNANCY; PREMATURITY; PROMOTER REGION; RISK FACTOR; UTERINE CERVIX; YOUNG ADULT;

ADULT; CERVIX UTERI; COHORT STUDIES; DNA METHYLATION; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; PREGNANCY; PREMATURE BIRTH; PROMOTER REGIONS, GENETIC; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RISK FACTORS; YOUNG ADULT;

EID: 84905643791     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.29170     Document Type: Article

References (38)

1. Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller AB, Narwal R, Adler A, Vera Garcia C, Rohde S, Say L, et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 2012; 379:2162-72; PMID:22682464; http://dx.doi. org/10.1016/S0140-6736(12)60820-4
2. Muglia LJ, Katz M. The enigma of spontaneous preterm birth. N Engl J Med 2010; 362:529-35; PMID:20147718; http://dx.doi.org/10.1056/ NEJMra0904308
3. David R, Collins J Jr. Disparities in infant mortality: what's genetics got to do with it? Am J Public Health 2007; 97:1191-7; PMID:17538073; http://dx.doi. org/10.2105/AJPH.2005.068387
4. Hecht JL, Fichorova RN, Tang VF, Allred EN, McElrath TF, Leviton A; Elgan Study Investigators. Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns. Pediatr Res 2011; 69:68-73; PMID:20921924; http://dx.doi.org/10.1203/PDR.0b013e3181fed334
5. Leviton A, Fichorova R, Yamamoto Y, Allred EN, Dammann O, Hecht J, Kuban K, McElrath T, O'Shea TM, Paneth N. Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation. Cytokine 2011; 53:66-73; PMID:20934883; http://dx.doi. org/10.1016/j.cyto.2010.09.003
6. Goldenberg RL, Andrews WW, Guerrant RL, Newman M, Mercer B, Iams J, Meis P, Moawad A, Das A, VanDorsten JP, et al.; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. Am J Obstet Gynecol 2000; 182:631-5; PMID:10739520; http://dx.doi.org/10.1067/ mob.2000.104211
7. Savitz DA, Dole N, Terry JW Jr., Zhou H, Thorp JM Jr. Smoking and pregnancy outcome among African-American and white women in central North Carolina. Epidemiology 2001; 12:636-42; PMID:11679790; http://dx.doi. org/10.1097/00001648-200111000-00010
8. Kramer MS, Séguin L, Lydon J, Goulet L. Socioeconomic disparities in pregnancy outcome: why do the poor fare so poorly? Paediatr Perinat Epidemiol 2000; 14:194-210; PMID:10949211; http://dx.doi. org/10.1046/j.1365-3016.2000.00266.x
9. David RJ, Collins JW Jr. Differing birth weight among infants of U.S.-born blacks, African-born blacks, and U.S.-born whites. N Engl J Med 1997; 337:1209-14; PMID:9337381; http://dx.doi. org/10.1056/NEJM199710233371706
10. Dizon-Townson DS. Preterm labour and delivery: a genetic predisposition. Paediatr Perinat Epidemiol 2001; 15(Suppl 2):57-62; PMID:11520400; http:// dx.doi.org/10.1046/j.1365-3016.2001.00008.x
11. Bollati V, Baccarelli A. Environmental epigenetics. Heredity (Edinb) 2010; 105:105-12; PMID:20179736; http://dx.doi.org/10.1038/ hdy.2010.2
12. Hou L, Wang D, Baccarelli A. Environmental chemicals and microRNAs. Mutat Res 2011; 714:105-12; PMID:21609724; http://dx.doi.org/10.1016/j. mrfmmm.2011.05.004
13. Breton CV, Byun HM, Wenten M, Pan F, Yang A, Gilliland FD. Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Respir Crit Care Med 2009; 180:462-7; PMID:19498054; http://dx.doi.org/10.1164/ rccm.200901-0135OC
14. Shenker NS, Ueland PM, Polidoro S, van Veldhoven K, Ricceri F, Brown R, Flanagan JM, Vineis P. DNA methylation as a long-term biomarker of exposure to tobacco smoke. Epidemiology 2013; 24:712-6; PMID:23867811; http://dx.doi.org/10.1097/ EDE.0b013e31829d5cb3
15. Bollati V, Schwartz J, Wright R, Litonjua A, Tarantini L, Suh H, Sparrow D, Vokonas P, Baccarelli A. Decline in genomic DNA methylation through aging in a cohort of elderly subjects. Mech Ageing Dev 2009; 130:234-9; PMID:19150625; http://dx.doi.org/10.1016/j.mad.2008.12.003
16. Mulligan CJ, D'Errico NC, Stees J, Hughes DA. Methylation changes at NR3C1 in newborns associate with maternal prenatal stress exposure and newborn birth weight. Epigenetics 2012; 7:853-7; PMID:22810058; http://dx.doi.org/10.4161/ epi.21180
17. Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 2009; 179:572-8; PMID:19136372; http://dx.doi.org/10.1164/ rccm.200807-1097OC
18. Burris HH, Rifas-Shiman SL, Baccarelli A, Tarantini L, Boeke CE, Kleinman K, Litonjua AA, Rich-Edwards JW, Gillman MW. Associations of LINE-1 DNA Methylation with Preterm Birth in a Prospective Cohort Study. J Dev Orig Health Dis 2012; 3:173-81; PMID:22720130; http://dx.doi. org/10.1017/S2040174412000104
19. Iams JD, Goldenberg RL, Meis PJ, Mercer BM, Moawad A, Das A, Thom E, McNellis D, Copper RL, Johnson F, et al.; National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network. The length of the cervix and the risk of spontaneous premature delivery. N Engl J Med 1996; 334:567-72; PMID:8569824; http:// dx.doi.org/10.1056/NEJM199602293340904
20. Gonzalez JM, Dong Z, Romero R, Girardi G. Cervical remodeling/ripening at term and preterm delivery: the same mechanism initiated by different mediators and different effector cells. PLoS One 2011; 6:e26877; PMID:22073213; http://dx.doi. org/10.1371/journal.pone.0026877
21. Burris HH, Braun JM, Byun HM, Tarantini L, Mercado A, Wright RJ, Schnaas L, Baccarelli AA, Wright RO, Tellez-Rojo MM. Association between birth weight and DNA methylation of IGF2, glucocorticoid receptor and repetitive elements LINE-1 and Alu. Epigenomics 2013; 5:271-81; PMID:23750643; http://dx.doi.org/10.2217/epi.13.24
22. Hoyo C, Fortner K, Murtha AP, Schildkraut JM, Soubry A, Demark-Wahnefried W, Jirtle RL, Kurtzberg J, Forman MR, Overcash F, et al. Association of cord blood methylation fractions at imprinted insulin-like growth factor 2 (IGF2), plasma IGF2, and birth weight. Cancer Causes Control 2012; 23:635-45; PMID:22392079; http://dx.doi. org/10.1007/s10552-012-9932-y
23. Wilhelm-Benartzi CS, Houseman EA, Maccani MA, Poage GM, Koestler DC, Langevin SM, Gagne LA, Banister CE, Padbury JF, Marsit CJ. In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. Environ Health Perspect 2012; 120:296-302; PMID:22005006; http://dx.doi. org/10.1289/ehp.1103927
24. Michels KB, Harris HR, Barault L. Birthweight, maternal weight trajectories and global DNA methylation of LINE-1 repetitive elements. PLoS One 2011; 6:e25254; PMID:21980406; http://dx.doi. org/10.1371/journal.pone.0025254
25. Tabano S, Colapietro P, Cetin I, Grati FR, Zanutto S, Mandò C, Antonazzo P, Pileri P, Rossella F, Larizza L, et al. Epigenetic modulation of the IGF2/ H19 imprinted domain in human embryonic and extra-embryonic compartments and its possible role in fetal growth restriction. Epigenetics 2010; 5:313-24; PMID:20418667; http://dx.doi.org/10.4161/ epi.5.4.11637
26. Guo L, Choufani S, Ferreira J, Smith A, Chitayat D, Shuman C, Uxa R, Keating S, Kingdom J, Weksberg R. Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae. Dev Biol 2008; 320:79-91; PMID:18550048; http://dx.doi.org/10.1016/j. ydbio.2008.04.025
27. Filiberto AC, Maccani MA, Koestler D, Wilhelm-Benartzi C, Avissar-Whiting M, Banister CE, Gagne LA, Marsit CJ. Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta. Epigenetics 2011; 6:566-72; PMID:21521940; http://dx.doi.org/10.4161/ epi.6.5.15236
28. Schroeder JW, Conneely KN, Cubells JC, Kilaru V, Newport DJ, Knight BT, Stowe ZN, Brennan PA, Krushkal J, Tylavsky FA, et al. Neonatal DNA methylation patterns associate with gestational age. Epigenetics 2011; 6:1498-504; PMID:22139580; http://dx.doi.org/10.4161/epi.6.12.18296
29. Parets SE, Conneely KN, Kilaru V, Fortunato SJ, Syed TA, Saade G, Smith AK, Menon R. Fetal DNA Methylation Associates with Early Spontaneous Preterm Birth and Gestational Age. PLoS One 2013; 8:e67489; PMID:23826308; http://dx.doi. org/10.1371/journal.pone.0067489
30. Swamy GK. Current methods of labor induction. Semin Perinatol 2012; 36:348-52; PMID:23009967; http://dx.doi.org/10.1053/j.semperi.2012.04.018
31. Gu G, Gao Q, Yuan X, Huang L, Ge L. Immunolocalization of adipocytes and prostaglandin E2 and its four receptor proteins EP1, EP2, EP3, and EP4 in the caprine cervix during spontaneous term labor. Biol Reprod 2012; 86:159, 1-10; PMID:22402965; http://dx.doi.org/10.1095/ biolreprod.111.096040
32. Sugino Y, Misawa A, Inoue J, Kitagawa M, Hosoi H, Sugimoto T, Imoto I, Inazawa J. Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas. Oncogene 2007; 26:7401-13; PMID:17533365; http://dx.doi. org/10.1038/sj.onc.1210550
33. Tian L, Suzuki M, Nakajima T, Kubo R, Sekine Y, Shibuya K, Hiroshima K, Nakatani Y, Fujisawa T, Yoshino I; Thoracic Surgery Group. Clinical significance of aberrant methylation of prostaglandin E receptor 2 (PTGER2) in nonsmall cell lung cancer: association with prognosis, PTGER2 expression, and epidermal growth factor receptor mutation. Cancer 2008; 113:1396-403; PMID:18666211; http:// dx.doi.org/10.1002/cncr.23694
34. Houseman EA, Accomando WP, Koestler DC, Christensen BC, Marsit CJ, Nelson HH, Wiencke JK, Kelsey KT. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 2012; 13:86; PMID:22568884; http://dx.doi.org/10.1186/1471-2105-13-86
35. Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, Burton J, Cox TV, Davies R, Down TA, et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 2006; 38:1378-85; PMID:17072317; http://dx.doi.org/10.1038/ng1909
36. Farkas SA, Milutin-Gašperov N, Grce M, Nilsson TK. Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer. Epigenetics 2013; 8:1213-25; PMID:24030264; http://dx.doi.org/10.4161/epi.26346
37. Dolfini D, Gatta R, Mantovani R. NF-Y and the transcriptional activation of CCAAT promoters. Crit Rev Biochem Mol Biol 2012; 47:29-49; PMID:22050321; http://dx.doi.org/10.3109/10409238.2011.628970
38. Yang AS, Estécio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004; 32:e38; PMID:14973332; http://dx.doi.org/10.1093/nar/ gnh032