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Volumn 9, Issue 3, 2014, Pages 286-296

MicroRNA therapeutics: The emerging anticancer strategies

Author keywords

Anticancer; Dicer; Drosha; Exportin 5; MicroRNAs; RNA interference; RNA induced silencing complex (RISC); Therapeutics

Indexed keywords

ANTINEOPLASTIC AGENT; MICRORNA;

EID: 84905638483     PISSN: 15748928     EISSN: 22123970     Source Type: Journal    
DOI: 10.2174/1574892809666140307101519     Document Type: Article
Times cited : (17)

References (73)
  • 1
    • 72949111146 scopus 로고    scopus 로고
    • MicroRNA regulation of cancer stem cells and therapeutic implications
    • DeSano TJ, Xu L. MicroRNA regulation of cancer stem cells and therapeutic implications. AAPS 2009; 4: 682-692.
    • (2009) AAPS , vol.4 , pp. 682-692
    • Desano, T.J.1    Xu, L.2
  • 2
    • 38349186896 scopus 로고    scopus 로고
    • MicroRNAs (miRNAs) in neurodegenerative diseases
    • Nelson PT, Wang WX, Rajeev BW. MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol 2008; 18(1): 130-138.
    • (2008) Brain Pathol , vol.18 , Issue.1 , pp. 130-138
    • Nelson, P.T.1    Wang, W.X.2    Rajeev, B.W.3
  • 4
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS, Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 2007; 21: 1025-1030.
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 5
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in can- cer: Rationale, strategies and challenges
    • Garzon R, Marcucci G, Croce MC. Targeting microRNAs in can- cer: Rationale, strategies and challenges. Nature 2010; 9: 775-789.
    • (2010) Nature , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, M.C.3
  • 6
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin AG, Croce MC. MicroRNA signatures in human cancers. Nature 2006; 6: 857-866.
    • (2006) Nature , vol.6 , pp. 857-866
    • Calin, A.G.1    Croce, M.C.2
  • 7
    • 84862614775 scopus 로고    scopus 로고
    • Emerging roles for modulation of microRNA signatures in cancer chemoprevention
    • Neelakandan K, Babu P, Nair S. Emerging roles for modulation of microRNA signatures in cancer chemoprevention. Curr Cancer Drug Targets 2012; 12(6): 716-740.
    • (2012) Curr Cancer Drug Targets , vol.12 , Issue.6 , pp. 716-740
    • Neelakandan, K.1    Babu, P.2    Nair, S.3
  • 8
    • 80054897516 scopus 로고    scopus 로고
    • MicroRNA signatures of stem cells
    • Das DK, Mukhopadhyay P. MicroRNA signatures of stem cells. Exp Clin Cardiol 2011; 16(3): 13-16.
    • (2011) Exp Clin Cardiol , vol.16 , Issue.3 , pp. 13-16
    • Das, D.K.1    Mukhopadhyay, P.2
  • 9
    • 83255194160 scopus 로고    scopus 로고
    • Chemical modification and design of anti-miRNA oligonucleotides
    • Lennox KA, Behlke MA. Chemical modification and design of anti-miRNA oligonucleotides. Gene Therapy 2011; 18: 1111-1120.
    • (2011) Gene Therapy , vol.18 , pp. 1111-1120
    • Lennox, K.A.1    Behlke, M.A.2
  • 10
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 11
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yenda-Muri S, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. PNAS 2004; 101(9): 2999-3004.
    • (2004) PNAS , vol.101 , Issue.9 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5    Yenda-Muri, S.6
  • 12
    • 78650179147 scopus 로고    scopus 로고
    • MicroRNA: A matter of life or death
    • Wang Z. MicroRNA: A matter of life or death. WJBC 2010; 1(4): 41-54.
    • (2010) WJBC , vol.1 , Issue.4 , pp. 41-54
    • Wang, Z.1
  • 13
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: MicroRNA biogenesis pathways and their regulation
    • Winter J, Jung S, Keller S, Gregory RI, Diederichs S. Many roads to maturity: MicroRNA biogenesis pathways and their regulation. Nat Cell Biol 2009; 11(3): 228-234.
    • (2009) Nat Cell Biol , vol.11 , Issue.3 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederichs, S.5
  • 14
    • 70449587068 scopus 로고    scopus 로고
    • Alternative processing of primary microRNA transcripts by Drosha generates 59 end variation of mature microRNA
    • Wu H, Ye C, Ramirez D, Manjunath N. Alternative processing of primary microRNA transcripts by Drosha generates 59 end variation of mature microRNA. Plos One 2009; 04: 1-12.
    • (2009) Plos One , vol.4 , pp. 1-12
    • Wu, H.1    Ye, C.2    Ramirez, D.3    Manjunath, N.4
  • 15
    • 46749090394 scopus 로고    scopus 로고
    • MicroRNA: An emerging therapeutic target and intervention tool
    • Liu Z, Sall A, Yang D. MicroRNA: An emerging therapeutic target and intervention tool. Int J Mol Sci 2008; 9: 978-999.
    • (2008) Int J Mol Sci , vol.9 , pp. 978-999
    • Liu, Z.1    Sall, A.2    Yang, D.3
  • 16
    • 33344477448 scopus 로고    scopus 로고
    • Genomics of microRNA
    • Kim VN, Nam JW. Genomics of microRNA. Trends Genet 2006; 22(3): 165-73.
    • (2006) Trends Genet , vol.22 , Issue.3 , pp. 165-173
    • Kim, V.N.1    Nam, J.W.2
  • 17
    • 77952690643 scopus 로고    scopus 로고
    • MicroRNAs, macrocontrol: Regulation of miRNA processing
    • Prochazka IS, Durmus S, Kroesen BJ, Berg AD. MicroRNAs, macrocontrol: Regulation of miRNA processing. RNA 2010; 16:1087-1095.
    • (2010) RNA , vol.16 , pp. 1087-1095
    • Prochazka, I.S.1    Durmus, S.2    Kroesen, B.J.3    Berg, A.D.4
  • 18
    • 77958050722 scopus 로고    scopus 로고
    • Mechanisms of control of microRNA biogenesis
    • Davis-Dusenbery BN, Hata A. Mechanisms of control of microRNA biogenesis. J. Biochem 2010; 148(4): 381-392.
    • (2010) J. Biochem , vol.148 , Issue.4 , pp. 381-392
    • Davis-Dusenbery, B.N.1    Hata, A.2
  • 19
    • 80053574171 scopus 로고    scopus 로고
    • Mirtrons: MicroRNA biogenesis via splicing
    • Westholm JO, Lai EC. Mirtrons: MicroRNA biogenesis via splicing. Biochimie 2011; 93: 1897-1904.
    • (2011) Biochimie , vol.93 , pp. 1897-1904
    • Westholm, J.O.1    Lai, E.C.2
  • 20
    • 84867681364 scopus 로고    scopus 로고
    • A comprehensive analyzis of precursor microRNA cleavage by human Dicer
    • Feng Y, Zhang X, Graves P, Zeng Y. A comprehensive analyzis of precursor microRNA cleavage by human Dicer. RNA 2012; 18: 2083-2092.
    • (2012) RNA , vol.18 , pp. 2083-2092
    • Feng, Y.1    Zhang, X.2    Graves, P.3    Zeng, Y.4
  • 21
    • 36048952786 scopus 로고    scopus 로고
    • Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development
    • Gironella M, Seux M, Xie MJ, Cano C, Tomasini R, Gommeaux J, et al. Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. PNAS 2007; 104(41): 16170-16175.
    • (2007) PNAS , vol.104 , Issue.41 , pp. 16170-16175
    • Gironella, M.1    Seux, M.2    Xie, M.J.3    Cano, C.4    Tomasini, R.5    Gommeaux, J.6
  • 23
    • 84886048409 scopus 로고    scopus 로고
    • c-Myc modulates microRNA processing via the transcriptional regulation of Drosha
    • Wang X, Zhao X, Gao P, Wu M. c-Myc modulates microRNA processing via the transcriptional regulation of Drosha. Scientific Reports 2013; 3: 1-7.
    • (2013) Scientific Reports , vol.3 , pp. 1-7
    • Wang, X.1    Zhao, X.2    Gao, P.3    Wu, M.4
  • 24
    • 79961095592 scopus 로고    scopus 로고
    • Biogenesis and regulation of cardiovascular MicroRNAs
    • Bauersachs J, Thum T. Biogenesis and regulation of cardiovascular MicroRNAs. Circulation Res 2011: 109: 334-347.
    • (2011) Circulation Res , vol.109 , pp. 334-347
    • Bauersachs, J.1    Thum, T.2
  • 25
    • 70349463161 scopus 로고    scopus 로고
    • The estrogen receptor-a-induced microRNA signature regulates itself and its transcriptional response
    • Castellanoa L, Giamasa G, Jacoba J, Coombesa RC, Lucchesib W, Thiruchelvama P, et al. The estrogen receptor-a-induced microRNA signature regulates itself and its transcriptional response. PNAS 2009; 106(27): 15732-15737.
    • (2009) PNAS , vol.106 , Issue.27 , pp. 15732-15737
    • Castellanoa, L.1    Giamasa, G.2    Jacoba, J.3    Coombesa, R.C.4    Lucchesib, W.5    Thiruchelvama, P.6
  • 26
    • 67649277689 scopus 로고    scopus 로고
    • The RNA-binding protein KSRP promotes the biogenesis of a subset of miRNAs
    • Trabucchi M, Briata P, Mayoral MG, Haase AD, Filipowicz W, Ramos A, et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of miRNAs. Nature 2009; 459(7249): 1010-1014.
    • (2009) Nature , vol.459 , Issue.7249 , pp. 1010-1014
    • Trabucchi, M.1    Briata, P.2    Mayoral, M.G.3    Haase, A.D.4    Filipowicz, W.5    Ramos, A.6
  • 27
    • 77957940475 scopus 로고    scopus 로고
    • A genetic defect in exportin-5 traps precursor MicroRNAs in the nucleus of cancer cells
    • Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, et al. A genetic defect in exportin-5 traps precursor MicroRNAs in the nucleus of cancer cells. Cancer Cell 2010; 18: 303-15.
    • (2010) Cancer Cell , vol.18 , pp. 303-315
    • Melo, S.A.1    Moutinho, C.2    Ropero, S.3    Calin, G.A.4    Rossi, S.5    Spizzo, R.6
  • 28
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, in-travasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SAK, Nikolova DA, Leupold JH, Colburn NH, Post S, et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, in-travasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-21236.
    • (2008) Oncogene , vol.27 , pp. 2128-21236
    • Asangani, I.A.1    Rasheed, S.A.K.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6
  • 29
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic MicroRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, et al. A polycistronic MicroRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005; 65: 9628-9632.
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3    Yamada, H.4    Yanagisawa, K.5    Tomida, S.6
  • 30
    • 48649099908 scopus 로고    scopus 로고
    • Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
    • Nagel R, Sage LC, Diosdado B, Waal DM, Vrielink OJ, Bolijn A, et al. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res 2008; 68: 5795-5802.
    • (2008) Cancer Res , vol.68 , pp. 5795-5802
    • Nagel, R.1    Sage, L.C.2    Diosdado, B.3    Waal, D.M.4    Vrielink, O.J.5    Bolijn, A.6
  • 32
    • 77949518018 scopus 로고    scopus 로고
    • MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
    • Han CY, Park CY, Bhagat G, Zhang J, Wang Y, Fan BJ, et al. MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. JEM 2010; 207(3): 475-489.
    • (2010) JEM , vol.207 , Issue.3 , pp. 475-489
    • Han, C.Y.1    Park, C.Y.2    Bhagat, G.3    Zhang, J.4    Wang, Y.5    Fan, B.J.6
  • 33
    • 63449135077 scopus 로고    scopus 로고
    • MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma
    • Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, Martino DD, et al. MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. Plos One 2009; 4: 1-14.
    • (2009) Plos One , vol.4 , pp. 1-14
    • Garzia, L.1    Andolfo, I.2    Cusanelli, E.3    Marino, N.4    Petrosino, G.5    Martino, D.D.6
  • 34
    • 36849078711 scopus 로고    scopus 로고
    • let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, Zhang X, Pan O, Gong C, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 137: 1109-1123.
    • (2007) Cell , vol.137 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3    Zhang, X.4    Pan, O.5    Gong, C.6
  • 35
    • 53949090314 scopus 로고    scopus 로고
    • Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
    • Ji Q, Hao X, Meng Y, Zhang M, DeSano J, Fan D, et al. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 2008; 8: 266-278.
    • (2008) BMC Cancer , vol.8 , pp. 266-278
    • Ji, Q.1    Hao, X.2    Meng, Y.3    Zhang, M.4    Desano, J.5    Fan, D.6
  • 36
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by MicroRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G, et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by MicroRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 2008; 68: 9125-9130.
    • (2008) Cancer Res , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3    Williams, S.4    Otsuki, A.5    Nuovo, G.6
  • 54
    • 84905641183 scopus 로고    scopus 로고
    • United States Patent and Trademark Office website, (Accessed on: August 12, 2013
    • United States Patent and Trademark Office website. Available at: http://www.uspto.gov/. (Accessed on: August 12, 2013).
  • 55
    • 85039605427 scopus 로고    scopus 로고
    • Espacenet website, Accessed on: August 12, 2013
    • Espacenet website. Available at: http://ep.espacenet.com/. (Accessed on: August 12, 2013).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.