P21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury

Gut

Volumn 63, Issue 9, 2014, Pages 1501-1512

  Marhenke, Silke ^a   Buitrago Molina, Laura Elisa ^a   Endig, Jessica ^a   Orlik, Johanna ^a   Schweitzer, Nora ^a   Klett, Stephanie ^a   Longerich, Thomas ^b   Geffers, Robert ^c   Muñoz, Aránzazu Sánchez ^d   Dorrell, Craig ^e   Katz, Sarah Fee ^f   Lechel, André ^f   Weng, Honglei ^g   Krech, Till ^a   Lehmann, Ulrich ^a   Dooley, Steven ^g   Rudolph, Karl Lenhard ^h   Manns, Michael P ^a   Vogel, Arndt ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f UNIVERSITY HOSPITAL ULM   (Germany)

^g MEDICAL FACULTY MANNHEIM HEIDELBERG UNIVERSITY   (Germany)

^h FRITZ LIPMANN INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN E; CYCLIN E1; CYTOKERATIN 19; POLO LIKE KINASE 1; STATHMIN; STATHMIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR FOXM1; UNCLASSIFIED DRUG;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PROGNOSIS; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CHRONIC CHOLESTATIC LIVER INJURY; CLONOGENESIS; COLONY FORMING UNIT; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE EXPRESSION; HEPATOCYTE TRANSPLANTATION; HEPATOMA CELL; HUMAN; IN VITRO STUDY; INFANT; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; LIVER FIBROSIS; LIVER INJURY; LIVER REGENERATION; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OVERALL SURVIVAL; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SURVIVAL RATE; SURVIVAL TIME;

CANCER; CELL CYCLE CONTROL; HEPATOCELLULAR CARCINOMA; LIVER;

ANIMALS; BIOLOGICAL MARKERS; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL LINE; CHOLESTASIS, INTRAHEPATIC; CHRONIC DISEASE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISEASE PROGRESSION; FEMALE; HEPATECTOMY; HEPATIC INSUFFICIENCY; HUMANS; LIVER NEOPLASMS; LIVER REGENERATION; MALE; MICE; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84905591202     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-304829     Document Type: Article

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