Using conditioned suppression to investigate compulsive drug seeking in rats

Drug and Alcohol Dependence

Volumn 142, Issue , 2014, Pages 314-324

  Limpens, Jules H W ^a   Schut, Evelien H S ^a   Voorn, Pieter ^b   Vanderschuren, Louk J M J ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cocaine; Compulsive behaviour; Conditioned suppression; Self administration; Sucrose

Indexed keywords

COCAINE; SUCROSE; DOPAMINE UPTAKE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVERSIVE BEHAVIOR; BEHAVIOR CONTROL; COMPULSION; CONDITIONED RESPONSE ANXIETY TEST; CONDITIONED SUPPRESSION; CONDITIONING; CONTROLLED STUDY; DRUG SEEKING BEHAVIOR; EVOKED RESPONSE; FEAR; FOOTSHOCK; MALE; MOTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION OPTIMIZATION; REINFORCEMENT; SELF ADMINISTRATION TEST; ADDICTION; ANIMAL; ANIMAL BEHAVIOR; AVOIDANCE BEHAVIOR; DRUG EFFECTS; DRUG SELF ADMINISTRATION; INSTRUMENTAL CONDITIONING; PHYSIOLOGY; WISTAR RAT;

RATTUS; RODENTIA;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; COCAINE; COMPULSIVE BEHAVIOR; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DRUG-SEEKING BEHAVIOR; MALE; RATS; RATS, WISTAR; REINFORCEMENT SCHEDULE; SELF ADMINISTRATION;

EID: 84905568670     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2014.06.037     Document Type: Article

References (47)

1. Ahmed S.H. The science of making drug-addicted animals. Neuroscience 2012, 211:107-125.
2. American Psychiatric Association DSM-IV-R Diagnostic and Statistical Manual of Mental Disorders. 2000, American Psychiatric Association, Washington, DC, USA.
3. American Psychiatric Association DSM-5 Diagnostic and Statistical Manual of Mental Disorders. 2013, American Psychiatric Association, Washington, DC, USA.
4. Annau Z., Kamin L.J. The conditioned emotional response as a function of intensity of the US. J. Comp. Physiol. Psychol. 1961, 54:428-432.
5. Bouton M.E. Context, time, and memory retrieval in the interference paradigms of Pavlovian conditioning. Psychol. Bull. 1993, 114:80-99.
6. Briand L.A., Flagel S.B., Garcia-Fuster M.J., Watson S.J., Akil H., Sarter M., Robinson T.E. Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine. Neuropsychopharmacology 2008, 33:2969-2980.
7. Cantin L., Lenoir M., Augier E., Vanhille N., Dubreucq S., Serre F., Vouillac C., Ahmed S.H. Cocaine is low on the value ladder of rats: possible evidence for resilience to addiction. PLoS One 2010, 5:e11592.
8. Christensen C.J., Silberberg A., Hursh S.R., Roma P.G., Riley A.L. Demand for cocaine and food over time. Pharmacol. Biochem. Behav. 2008, 91:209-216.
9. Cooper A., Barnea-Ygael N., Levy D., Shaham Y., Zangen A. A conflict rat model of cue-induced relapse to cocaine seeking. Psychopharmacology 2007, 194:117-125.
10. Del Olmo N., Higuera-Matas A., Miguens M., Garcia-Lecumberri C., Ambrosio E. Cocaine self-administration improves performance in a highly demanding water maze task. Psychopharmacology 2007, 195:19-25.
11. Deroche-Gamonet V., Belin D., Piazza P.V. Evidence for addiction-like behavior in the rat. Science 2004, 305:1014-1017.
12. Dickinson A., Wood N., Smith J.W. Alcohol seeking by rats: action or habit?. Q. J. Exp. Psychol. B 2002, 55:331-348.
13. 1 receptor antagonism. Neuropharmacology 2012, 62:1142-1151.
14. Fanselow M.S. Conditioned and unconditional components of post-shock freezing. Pavlov J. Biol. Sci. 1980, 15:177-182.
15. Freeman K.B., McMaster B.C., Roma P.G., Woolverton W.L. Assessment of the effects of contingent histamine injections on the reinforcing effectiveness of cocaine using behavioral economic and progressive-ratio designs. Psychopharmacology 2014, 10.1007/s00213-013-3396-y.
16. Garavan H., Stout J.C. Neurocognitive insights into substance abuse. Trends Cogn. Sci. 2005, 9:195-201.
17. Goldstein R.Z., Volkow N.D. Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat. Rev. Neurosci. 2011, 12:652-669.
18. Hopf F.W., Chang S.J., Sparta D.R., Bowers M.S., Bonci A. Motivation for alcohol becomes resistant to quinine adulteration after 3 to 4 months of intermittent alcohol self-administration. Alcohol. Clin. Exp. Res. 2010, 34:1565-1573.
19. Jonkman S., Pelloux Y., Everitt B.J. Drug intake is sufficient, but conditioning is not necessary for the emergence of compulsive cocaine seeking after extended self-administration. Neuropsychopharmacology 2012, 37:1612-1619.
20. Kearns D.N., Weiss S.J., Panlilio L.V. Conditioned suppression of behavior maintained by cocaine self-administration. Drug Alcohol Depend. 2002, 65:253-261.
21. Kearns D.N., Gomez-Serrano M.A., Tunstall B.J. A review of preclinical research demonstrating that drug and non-drug reinforcers differentially affect behavior. Curr. Drug Abuse Rev. 2011, 4:261-269.
22. Kerstetter K.A., Ballis M.A., Duffin-Lutgen S., Carr A.E., Behrens A.M., Kippin T.E. Sex differences in selecting between food and cocaine reinforcement are mediated by estrogen. Neuropsychopharmacology 2012, 37:2605-2614.
23. Koob G.F., Kenneth L.G., Mason B.J. Development of pharmacotherapies for drug addiction: a Rosetta stone approach. Nat. Rev. Drug Discov. 2009, 8:500-515.
24. Lenoir M., Serre F., Cantin L., Ahmed S.H. Intense sweetness surpasses cocaine reward. PLoS One 2007, 8:e698.
25. Leshner A.I. Addiction is a brain disease, and it matters. Science 1997, 278:45-47.
26. Lesscher H.M.B., van Kerkhof L.W.M., Vanderschuren L.J.M.J. Inflexible and indifferent alcohol drinking in male mice. Alcohol. Clin. Exp. Res. 2010, 34:1219-1225.
27. Lesscher H.M.B., Vanderschuren L.J.M.J. Compulsive drug use and its neural substrates. Rev. Neurosci. 2012, 23:731-745.
28. Maren S. Overtraining does not mitigate contextual fear conditioning deficits produced by neurotoxic lesions of the basolateral amygdala. J. Neurosci. 1998, 18:3088-3097.
29. Morris R.W., Bouton M.E. Effect of unconditioned stimulus magnitude on the emergence of conditioned responding. J. Exp. Psychol. Anim. Behav. Process. 2006, 32:371-385.
30. Nader M.A., Morgan D. Effects of negative punishment contingencies on cocaine self-administration by rhesus monkeys. Behav. Pharmacol. 2001, 12:91-99.
31. O'Brien C.P. Evidence-based treatments of addiction. Philos. Trans. R. Soc. Lond. B Biol. Sci. 2008, 363:3277-3286.
32. O'Brien C.P., McLellan A.T. Myths about the treatment of addiction. Lancet 1996, 347:237-240.
33. Olmstead M.C., Parkinson J.A., Miles F.J., Everitt B.J., Dickinson A. Cocaine-seeking by rats: regulation, reinforcement and activation. Psychopharmacology 2000, 152:123-131.
34. Pelloux Y., Everitt B.J., Dickinson A. Compulsive drug seeking by rats under punishment: effects of drug taking history. Psychopharmacology 2007, 194:127-137.
35. Perry A.N., Westenbroek C., Becker J.B. The development of a preference for cocaine over food identifies individual rats with addiction-like behaviors. PLoS One 2013, 8:e79465.
36. Pierce R.C., O'Brien C.P., Kenny P.J., Vanderschuren L.J.M.J. Rational development of addiction pharmacotherapies: successes, failures, and prospects. Cold Spring Harb. Perspect. Med. 2012, 2:a012880.
37. Rogers J.L., Ghee S., See R.E. The neural circuitry underlying reinstatement of heroin-seeking behavior in an animal model of relapse. Neuroscience 2008, 151:579-588.
38. Seif T., Chang S.J., Simms J.A., Gibb S.L., Dadgar J., Chen B.T., Harvey B.K., Ron D., Messing R.O., Bonci A., Hopf F.W. Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake. Nat. Neurosci. 2013, 16:1094-1100.
39. Simon N.W., Gilbert R.J., Mayse J.D., Bizon J.L., Setlow B. Balancing risk and reward: a rat model of risky decision making. Neuropsychopharmacology 2009, 34:2208-2217.
40. United Nations Office on Drugs and Crime World Drug Report 2012 2012, United Nations, Vienna, Austria.
41. van den Brink W. Evidence-based pharmacological treatment of substance use disorders and pathological gambling. Curr. Drug Abuse Rev. 2012, 5:3-31.
42. Vanderschuren L.J.M.J., Ahmed S.H. Animal studies of addictive behavior. Cold Spring Harb. Perspect. Med. 2013, 3:a011932.
43. Vanderschuren L.J.M.J., Everitt B.J. Drug seeking becomes compulsive after prolonged cocaine self-administration. Science 2004, 305:1017-1019.
44. Veeneman M.M.J., van Ast M., Broekhoven M.H., Limpens J.H.W., Vanderschuren L.J.M.J. Seeking-taking chain schedules of cocaine and sucrose self-administration: effects of reward size, reward omission, and alpha-flupenthixol. Psychopharmacology 2012, 220:771-785.
45. Volkow N.D., Li T.K. Drug addiction: the neurobiology of behaviour gone awry. Nat. Rev. Neurosci. 2004, 5:963-970.
46. Wolffgramm J. An ethopharmacological approach to the development of drug addiction. Neurosci. Biobehav. Rev. 1991, 15:515-519.
47. World Health Organization Global Status Report On Alcohol 2004 2004, World Health Organization, Geneva, Switzerland.