Continuous digital hypothermia initiated after the onset of lameness prevents lamellar failure in the oligofructose laminitis model

Equine Veterinary Journal

Volumn 46, Issue 5, 2014, Pages 625-630

  van Eps, A W ^a   Pollitt, C C ^a   Underwood, C ^a   Medina Torres, C E ^a   Goodwin, W A ^a   Belknap, J K ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Cryotherapy; Horse; Hypothermia; Laminitis; Sepsis

Indexed keywords

FRUCTOSE OLIGOSACCHARIDE; OLIGOSACCHARIDE;

ANALGESIA; ANIMAL; ANIMAL LAMENESS; CHEMICALLY INDUCED; CRYOTHERAPY; FOOT DISEASES; HOOF AND CLAW; HORSE; HORSE DISEASE; INFLAMMATION; PATHOLOGY; TIME; VETERINARY;

ANALGESIA; ANIMALS; CRYOTHERAPY; FOOT DISEASES; HOOF AND CLAW; HORSE DISEASES; HORSES; INFLAMMATION; LAMENESS, ANIMAL; OLIGOSACCHARIDES; TIME FACTORS;

EID: 84905566949     PISSN: 04251644     EISSN: 20423306     Source Type: Journal    
DOI: 10.1111/evj.12180     Document Type: Article

References (47)

1. van Eps, A.W. (2010) Acute laminitis: medical and supportive therapy. Vet. Clin. N. Am.: Equine Pract. 26, 103-114.
2. Pollitt, C.C. (1996) Basement membrane pathology: a feature of acute equine laminitis. Equine Vet. J. 28, 38-46.
3. Belknap, J.K., Giguere, S., Pettigrew, A., Cochran, A.M., Van Eps, A.W. and Pollitt, C.C. (2007) Lamellar pro-inflammatory cytokine expression patterns in laminitis at the developmental stage and at the onset of lameness: innate vs. adaptive immune response. Equine Vet. J. 39, 42-47.
4. Johnson, P.J., Tyagi, S.C., Katwa, L.C., Ganjam, V.K., Moore, L.A., Kreeger, J.M. and Messer, N.T. (1998) Activation of extracellular matrix metalloproteinases in equine laminitis. Vet. Rec. 142, 392-396.
5. Leise, B.S., Faleiros, R.R., Watts, M., Johnson, P.J., Black, S.J. and Belknap, J.K. (2011) Laminar inflammatory gene expression in the carbohydrate overload model of equine laminitis. Equine Vet. J. 43, 54-61.
6. Coyne, M.J., Cousin, H., Loftus, J.P., Johnson, P.J., Belknap, J.K., Gradil, C.M., Black, S.J. and Alfandari, D. (2009) Cloning and expression of ADAM-related metalloproteases in equine laminitis. Vet. Immunol. Immunopathol. 129, 231-241.
7. Visser, M.B. and Pollitt, C.C. (2012) The timeline of metalloprotease events during oligofructose induced equine laminitis development. Equine Vet. J. 44, 88-93.
8. Visser, M.B. and Pollitt, C.C. (2011) Lamellar leukocyte infiltration and involvement of IL-6 during oligofructose-induced equine laminitis development. Vet. Immunol. Immunopathol. 144, 120-128.
9. de Laat, M.A., Kyaw-Tanner, M.T., Nourian, A.R., McGowan, C.M., Sillence, M.N. and Pollitt, C.C. (2011) The developmental and acute phases of insulin-induced laminitis involve minimal metalloproteinase activity. Vet. Immunol. Immunopathol. 140, 275-281.
10. de Laat, M.A., van Eps, A.W., McGowan, C.M., Sillence, M.N. and Pollitt, C.C. (2011) Equine laminitis: comparative histopathology 48 hours after experimental induction with insulin or alimentary oligofructose in standardbred horses. J. Comp. Pathol. 145, 399-409.
11. Nourian, A.R., Asplin, K.E., McGowan, C.M., Sillence, M.N. and Pollitt, C.C. (2009) Equine laminitis: ultrastructural lesions detected in ponies following hyperinsulinaemia. Equine Vet. J. 41, 671-677.
12. van Eps, A.W. and Pollitt, C.C. (2004) Equine laminitis: cryotherapy reduces the severity of the acute lesion. Equine Vet. J. 36, 255-260.
13. Van Eps, A.W. and Pollitt, C.C. (2009) Equine laminitis model: cryotherapy reduces the severity of lesions evaluated seven days after induction with oligofructose. Equine Vet. J. 41, 741-746.
14. van Eps, A.W., Leise, B.S., Watts, M., Pollitt, C.C. and Belknap, J.K. (2012) Digital hypothermia inhibits early lamellar inflammatory signalling in the oligofructose laminitis model. Equine Vet. J. 44, 230-237.
15. Kullman, A., Holcombe, S.J., Hurcombe, S.D., Roessner, H.A., Hauptman, J.G., Geor, R.J. and Belknap, J. (2013) Prophylactic digital cryotherapy was associated with decreased incidence of laminitis in horses diagnosed with colitis. Equine Vet. J. Epub ahead of print; doi:10.1111/evj.12156.
16. Swenson, C., Sward, L. and Karlsson, J. (1996) Cryotherapy in sports medicine. Scand. J. Med. Sci. Sports 6, 193-200.
17. Lim, C.M., Kim, M.S., Ahn, J.J., Kim, M.J., Kwon, Y., Lee, I., Koh, Y., Kim, D.S. and Kim, W.D. (2003) Hypothermia protects against endotoxin-induced acute lung injury in rats. Intensive Care Med. 29, 453-459.
18. Westermann, S., Vollmar, B., Thorlacius, H. and Menger, M.D. (1999) Surface cooling inhibits tumor necrosis factor-alpha-induced microvascular perfusion failure, leukocyte adhesion, and apoptosis in the striated muscle. Surgery 126, 881-889.
19. Webster, C.M., Kelly, S., Koike, M.A., Chock, V.Y., Giffard, R.G. and Yenari, M.A. (2009) Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia. Neurobiol. Dis. 33, 301-312.
20. Scumpia, P.O., Sarcia, P.J., Kelly, K.M., DeMarco, V.G. and Skimming, J.W. (2004) Hypothermia induces anti-inflammatory cytokines and inhibits nitric oxide and myeloperoxidase-mediated damage in the hearts of endotoxemic rats. Chest 125, 1483-1491.
21. Prandini, M.N., Neves Filho, A., Lapa, A.J. and Stavale, J.N. (2005) Mild hypothermia reduces polymorphonuclear leukocytes infiltration in induced brain inflammation. Arq. Neuropsiquiatr 63, 779-784.
22. Kamler, M., Goedeke, J., Pizanis, N., Milekhin, V., Schade, F.U. and Jakob, H. (2005) In vivo effects of hypothermia on the microcirculation during extracorporeal circulation. Eur. J. Cardiothorac Surg. 28, 259-265.
23. Novack, T.A., Dillon, M.C. and Jackson, W.T. (1996) Neurochemical mechanisms in brain injury and treatment: a review. J. Clin. Expt. Neuropsychol. 18, 685-706.
24. van Eps, A.W. and Pollitt, C.C. (2006) Equine laminitis induced with oligofructose. Equine Vet. J. 38, 203-208.
25. Obel, N. (1948) Studies of the Histopathology of Acute Laminitis. Almgvist and Wilcsells Bottrykeri Ab Uppsala (Thesis).
26. Driessen, B., Scandella, M. and Zarucco, L. (2008) Development of a technique for continuous perineural blockade of the palmar nerves in the distal equine thoracic limb. Vet. Anaesth. Analg. 35, 432-448.
27. Zarucco, L., Driessen, B., Scandella, M., Cozzi, F. and Cantile, C. (2010) Sensory nerve conduction and nociception in the equine lower forelimb during perineural bupivacaine infusion along the palmar nerves. Can. J. Vet. Res. 74, 305-313.
28. Landis, J.R. and Koch, G.G. (1977) The measurement of observer agreement for categorical data. Biomet. 33, 159-174.
29. Van Eps, A.W. and Pollitt, C.C. (2009) Equine laminitis model: lamellar histopathology seven days after induction with oligofructose. Equine Vet. J. 41, 735-740.
30. Lane, L.E. (1971) Localized hypothermia for the relief of pain in musculoskeletal injuries. Phys. Ther. 51, 182-183.
31. Lehmann, J.F. (1979) Therapeutic heat and cold. Arch. Phys. Med. Rehab. 60, 561-561.
32. Pollitt, C.C. and Visser, M.B. (2010) Carbohydrate alimentary overload laminitis. Vet. Clin. N. Am.: Equine Pract. 26, 65-78.
33. Bailey, S.R., Adair, H.S., Reinemeyer, C.R., Morgan, S.J., Brooks, A.C., Longhofer, S.L. and Elliott, J. (2009) Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. Vet. Immunol. Immunopathol. 129, 167-173.
34. Blikslager, A.T., Yin, C., Cochran, A.M., Wooten, J.G., Pettigrew, A. and Belknap, J.K. (2006) Cyclooxygenase expression in the early stages of equine laminitis: a cytologic study. J. Vet. Intern. Med. 20, 1191-1196.
35. Jia, F., Pan, Y.H., Mao, Q., Liang, Y.M. and Jiang, J.Y. (2010) Matrix metalloproteinase-9 expression and protein levels after fluid percussion injury in rats: the effect of injury severity and brain temperature. J. Neurotrauma 27, 1059-1068.
36. Hastbacka, J., Tiainen, M., Hynninen, M., Kolho, E., Tervahartiala, T., Sorsa, T., Lauhio, A. and Pettila, V. (2012) Serum matrix metalloproteinases in patients resuscitated from cardiac arrest. The association with therapeutic hypothermia. Resuscitation 83, 197-201.
37. Wu, T.C. and Grotta, J.C. (2013) Hypothermia for acute ischaemic stroke. Lancet Neurol. 12, 275-284.
38. Tagin, M.A., Woolcott, C.G., Vincer, M.J., Whyte, R.K. and Stinson, D.A. (2012) Hypothermia for neonatal hypoxic ischemic encephalopathy: an updated systematic review and meta-analysis. Arch. Pediatr. Adolesc. Med. 166, 558-566.
39. Lampe, J.W. and Becker, L.B. (2011) State of the art in therapeutic hypothermia. Annu. Rev. Med. 62, 79-93.
40. Rim, K.P., Kim, K., Jo, Y.H., Lee, J.H., Rhee, J.E., Kang, K.W., Suh, G.J., Kwon, W.Y., Lee, M.J. and Lee, H.S. (2012) Effect of therapeutic hypothermia according to severity of sepsis in a septic rat model. Cytokine 60, 755-761.
41. Chang, Y.T., Wann, S.R., Tsai, J.S., Kao, C.H., Lee, P.T., Huang, N.C., Yen, C.C., Huang, M.S. and Chang, H.T. (2013) The role of autonomic nervous system function in hypothermia-mediated sepsis protection. Am. J. Emerg. Med. 31, 375-380.
42. Crouser, E.D. (2012) Warming up to hypothermia for treatment of severe sepsis. Crit. Care Med. 40, 1020-1022.
43. Acosta-Lara, P. and Varon, J. (2013) Therapeutic hypothermia in sepsis: to use or not to use? Am. J. Emerg. Med. 31, 381-382.
44. Beurskens, C.J., Aslami, H., Kuipers, M.T., Horn, J., Vroom, M.B., van Kuilenburg, A.B., Roelofs, J.J., Schultz, M.J. and Juffermans, N.P. (2012) Induced hypothermia is protective in a rat model of pneumococcal pneumonia associated with increased adenosine triphosphate availability and turnover. Crit. Care Med. 40, 919-926.
45. Fujimoto, K., Fujita, M., Tsuruta, R., Tanaka, R., Shinagawa, H., Izumi, T., Kasaoka, S. and Maekawa, T. (2008) Early induction of moderate hypothermia suppresses systemic inflammatory cytokines and intracellular adhesion molecule-1 in rats with caerulein-induced pancreatitis and endotoxemia. Pancreas 37, 176-181.
46. Chin, J.Y., Koh, Y., Kim, M.J., Kim, H.S., Kim, W.S., Kim, D.S., Kim, W.D. and Lim, C.M. (2007) The effects of hypothermia on endotoxin-primed lung. Anesth. Analg. 104, 1171-1178, tables of contents.
47. Lee, J.H., Kim, K., Jo, Y.H., Kim, M.A., Rim, K.P., Kang, K.W., Rhee, J.E., Lee, M.J., Lee, H.S., Kwon, W.Y. and Suh, G.J. (2013) Therapeutic hypothermia attenuates liver injury in polymicrobial sepsis model of rats via Akt survival pathway. J. Surg. Res. 181, 114-120.