Combined screening for serum anti-nuclear and anti-aquaporin-4 antibodies improves diagnostic accuracy for distinguishing neuromyelitis optica from multiple sclerosis

European Neurology

Volumn 72, Issue 1-2, 2014, Pages 103-108

  Wu, Lei ^a   Huang, Dehui ^a   Yang, Yang ^a   Wu, Weiping ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Anti nuclear antibodies; Aquaporin 4; Longitudinally extensive transverse myelitis; Multiple sclerosis; Neuromyelitis optica

Indexed keywords

ANTINUCLEAR ANTIBODY; AQUAPORIN 4 ANTIBODY; ANTIBODY; AQUAPORIN 4; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; AGED; ANTIBODY BLOOD LEVEL; ARTICLE; CHILD; CHINESE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; MYELITIS; MYELOOPTIC NEUROPATHY; NEUROMYELITIS OPTICA SPECTRUM DISORDER; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEROPREVALENCE; BLOOD; DIFFERENTIAL DIAGNOSIS; IMMUNOLOGY; MIDDLE AGED; NEUROMYELITIS OPTICA; PROSPECTIVE STUDY; YOUNG ADULT; CONTROLLED STUDY; OPTIC NEURITIS; RECURRENT DISEASE; RECURRENT LONGITUDINALLY EXTENSIVE TRANSVERSE MYELITIS; RECURRENT OPTIC NEURITIS; SCREENING;

ADOLESCENT; ADULT; AGED; ANTIBODIES; ANTIBODIES, ANTINUCLEAR; AQUAPORIN 4; BIOLOGICAL MARKERS; CHILD; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NEUROMYELITIS OPTICA; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84905560510     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000358218     Document Type: Article

References (40)

1. Lana-Peixoto MA: Devic's neuromyelitis optica: a critical review. Arq Neuropsiquiatr 2008; 66: 120-138.
2. Galetta SL, Bennett J: Neuromyelitis optica is a variant of multiple sclerosis. Arch Neurol 2007; 64: 901-903.
3. Lana-Peixoto MA, Callegaro D: The expanded spectrum of neuromyelitis optica: evidences for a new definition. Arq Neuropsiquiatr 2012; 70: 807-813.
4. Jacob A, Panicker J, Lythgoe D, Elsone L, Mutch K, Wilson M, Das K, Boggild M: The epidemiology of neuromyelitis optica amongst adults in the Merseyside County of United Kingdom. J Neurol 2013; 260: 2134-2137.
5. Houzen H, Niino M, Hirotani M, Fukazawa T, Kikuchi S, Tanaka K, Sasaki H: Increased prevalence, incidence, and female predominance of multiple sclerosis in Northern Japan. J Neurol Sci 2012; 323: 117-122.
6. Asgari N, Lillevang ST, Skejoe HP, Falah M, Stenager E, Kyvik KO: A population-based study of neuromyelitis optica in Caucasians. Neurology 2011; 76: 1589-1595.
7. Collongues N, Marignier R, Zephir H, Papeix C, et al: Neuromyelitis optica in France: a multicenter study of 125 patients. Neurology 2010; 74: 736-742.
8. Wingerchuk DM, Hogancamp WF, O'Brien PC, Weinshenker BG: The clinical course of neuromyelitis optica (Devic's syndrome). Neurology 1999; 53: 1107-1114.
9. Lennon VA, Wingerchuk DM, Kryzer TJ, Pittock SJ, Lucchinetti CF, Fujihara K, Nakashima I, Weinshenker BG: A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004; 364: 2106-2112.
10. Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR: IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005; 202: 473-477.
11. Graber DJ, Levy M, Kerr D, Wade WF: Neuromyelitis optica pathogenesis and aquaporin 4. J Neuroinflammation 2008; 5: 22.
12. Saiz A, Zuliani L, Blanco Y, Tavolato B, Giometto B, Graus F: Revised diagnostic criteria for neuromyelitis optica (NMO). Application in a series of suspected patients. J Neurol 2007; 254: 1233-1237.
13. Waters P, Jarius S, Littleton E, Leite MI, Jacob S, Gray B, Geraldes R, Vale T, Jacob A, Palace J, Maxwell S, Beeson D, Vincent A: Aquaporin- 4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis. Arch Neurol 2008; 65: 913-919.
14. Wingerchuk DM, Lennon VA, Lucchinetti CF, Pittock SJ, Weinshenker BG: The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6: 805-815.
15. Goulvestre C: Antinuclear antibodies (in French). Presse Med 2006; 35: 287-295.
16. Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG: Revised diagnostic criteria for neuromyelitis optica. Neurology 2006; 66: 1485-1489.
17. Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L, Lublin FD, Metz LM, McFarland HF, O'Connor PW, Sandberg- Wollheim M, Thompson AJ, Weinshenker BG, Wolinsky JS: Diagnostic criteria for multiple sclerosis: 2005 revisions to the 'McDonald Criteria'. Ann Neurol 2005; 58: 840-846.
18. Marignier R, Bernard-Valnet R, Giraudon P, Collongues N, Papeix C, Zephir H, Cavillon G, Rogemond V, Casey R, Frangoulis B, De Seze J, Vukusic S, Honnorat J, Confavreux C: Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity-dependent entity. Neurology 2013; 80: 2194-2200.
19. Kang ES, Min JH, Lee KH, Kim BJ: Clinical usefulness of cell-based indirect immunofluorescence assay for the detection of aquaporin- 4 antibodies in neuromyelitis optica spectrum disorder. Ann Lab Med 2012; 32: 331-338.
20. Waters PJ, McKeon A, Leite MI, Rajasekharan S, Lennon VA, Villalobos A, Palace J, Mandrekar JN, Vincent A, Bar-Or A, Pittock SJ: Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays. Neurology 2012; 78: 665-671; discussion 669.
21. Sato D, Callegaro D, Lana-Peixoto MA, Fujihara K; Brazilian Committee for Treatment and Research in Multiple Sclerosis: Treatment of neuromyelitis optica: an evidence based review. Arq Neuropsiquiatr 2012; 70: 59-66.
22. Deretzi G, Kountouras J, Koutlas E, Zavos C, Polyzos S, Rudolf J, Grigoriadis N, Gavalas E, Boziki M, Tsiptsios I: Familial prevalence of autoimmune disorders in multiple sclerosis in Northern Greece. Mult Scler 2010; 16: 1091-1101.
23. Garg N, Zivadinov R, Ramanathan M, Vasiliu I, Locke J, Watts K, Lema J, Rajeswary J, Munschauer FE, Ambrus J Jr, Weinstock-Guttman B: Clinical and MRI correlates of autoreactive antibodies in multiple sclerosis patients. J Neuroimmunol 2007; 187: 159-165.
24. Wei Q, Bundell C, Wu JS, Castley A, James I, Hollingsworth P, Christiansen F, Carroll WM, Mastaglia FL, Kermode AG: Low level of systemic autoimmunity in Western Australian multiple sclerosis patients. Mult Scler 2010; 16: 351-354.
25. Paul F, Jarius S, Aktas O, Bluthner M, Bauer O, Appelhans H, Franciotta D, Bergamaschi R, Littleton E, Palace J, Seelig HP, Hohlfeld R, Vincent A, Zipp F: Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica. PLoS Med 2007; 4:e133.
26. Yang Y, Huang DH, Wu WP, Wu L, Chen LF, Wu Q: The role of aquaporin-4 antibodies in Chinese patients with neuromyelitis optica. J Clin Neurosci 2013; 20: 94-98.
27. Mealy MA, Wingerchuk DM, Greenberg BM, Levy M: Epidemiology of neuromyelitis optica in the United States: a multicenter analysis. Arch Neurol 2012; 69: 1176-1180.
28. Jarius S, Ruprecht K, Wildemann B, Kuempfel T, et al: Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients. J Neuroinflammation 2012; 9: 14.
29. Ketelslegers IA, Modderman PW, Vennegoor A, Killestein J, Hamann D, Hintzen RQ: Antibodies against aquaporin-4 in neuromyelitis optica: distinction between recurrent and monophasic patients. Mult Scler 2011; 17: 1527-1530.
30. Wang KC, Tsai CP, Lee CL, Chen SY, Chen SJ: The prevalence of long spinal cord lesions and anti-aquaporin 4 antibodies in neuromyelitis optica patients in Taiwan. Eur Neurol 2011; 65: 99-104.
31. Chan KH, Ramsden DB, Yu YL, Kwok KH, Chu AC, Ho PW, Kwan JS, Lee R, Lim E, Kung MH, Ho SL: Neuromyelitis optica-IgG in idiopathic inflammatory demyelinating disorders amongst Hong Kong Chinese. Eur J Neurol 2009; 16: 310-316.
32. Adoni T, Lino AM, Marchiori PE, Kok F, Callegaro D: Seroprevalence of NMO-IgG antibody in Brazilian patients with neuromyelitis optica. Arq Neuropsiquiatr 2008; 66: 295-297.
33. Weinshenker BG, Wingerchuk DM, Vukusic S, Linbo L, Pittock SJ, Lucchinetti CF, Lennon VA: Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis. Ann Neurol 2006; 59: 566-569.
34. Banwell B, Tenembaum S, Lennon VA, Ursell E, Kennedy J, Bar-Or A, Weinshenker BG, Lucchinetti CF, Pittock SJ: Neuromyelitis optica- IgG in childhood inflammatory demyelinating CNS disorders. Neurology 2008; 70: 344-352.
35. Pittock SJ: Neuromyelitis optica: a new perspective. Semin Neurol 2008; 28: 95-104.
36. Pittock SJ, Lennon VA, de Seze J, Vermersch P, Homburger HA, Wingerchuk DM, Lucchinetti CF, Zephir H, Moder K, Weinshenker BG: Neuromyelitis optica and non organ-specific autoimmunity. Arch Neurol 2008; 65: 78-83.
37. Spencer-Green G, Alter D, Welch HG: Test performance in systemic sclerosis: anti-centromere and anti-Scl-70 antibodies. Am J Med 1997; 103: 242-248.
38. Marignier R, Bernard-Valnet R, Giraudon P, Collongues N, Papeix C, Zephir H, Cavillon G, Rogemond V, Casey R, Frangoulis B, De Seze J, Vukusic S, Honnorat J, Confavreux C, Group NS: Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity- dependent entity. Neurology 2013; 80: 2194-2200.
39. Szmyrka-Kaczmarek M, Pokryszko-Dragan A, Pawlik B, Gruszka E, Korman L, Podemski R, Wiland P, Szechinski J: Antinuclear and antiphospholipid antibodies in patients with multiple sclerosis. Lupus 2012; 21: 412-420.
40. Fromont A, Binquet C, Rollot F, Despalins R, Weill A, Clerc L, Bonithon-Kopp C, Moreau T: Comorbidities at multiple sclerosis diagnosis. J Neurol 2013; 260: 2629-2637.