Analysis of biodistribution of intracranially infused radiolabeled interleukin-13 receptor-targeted immunotoxin IL-13PE by SPECT/CT in an orthotopic mouse model of human glioma

Journal of Nuclear Medicine

Volumn 55, Issue 8, 2014, Pages 1323-1329

  Suzuki, Akiko ^a   Leland, Pamela ^a   Kobayashi, Hisataka ^b   Choyke, Peter L ^b   Jagoda, Elaine M ^b   Inoue, Tomio ^c   Joshi, Bharat H ^a   Puri, Raj K ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Biodistribution; Brain tumor; Convection enhanced delivery; IL 13PE; Radioiodination; SPECT

Indexed keywords

INTERLEUKIN 13 RECEPTOR; IODINE INTERLEUKIN 13 PSEUDOMONAS EXOTOXIN I 125; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; IMMUNOTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG RECEPTOR BINDING; DRUG UPTAKE; GLIOBLASTOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ANIMAL; BRAIN; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC USE; DISEASE MODEL; GLIOMA; INJECTION; ISOTOPE LABELING; METABOLISM; PATHOLOGY; PSEUDOMONAS; RADIOGRAPHY; SCINTISCANNING; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; BRAIN; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; GLIOMA; HUMANS; IMMUNOTOXINS; INJECTIONS; ISOTOPE LABELING; MICE; PSEUDOMONAS; RECEPTORS, INTERLEUKIN-13; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84905514683     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.114.138404     Document Type: Article

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