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Volumn 28, Issue 3, 2005, Pages 193-202

Evidence that IL-13Rα2 chain in human glioma cells is responsible for the antitumor activity mediated by receptor-directed cytotoxin therapy

Author keywords

Antisense oligonucleotide; Gene therapy; Glioblastoma; Immunotoxin; Interleukin 13 receptor

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; CYTOTOXIN; INTERLEUKIN 13; INTERLEUKIN 13 PE38; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 13 RECEPTOR ALPHA2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 17844401189     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.cji.0000161393.04207.e1     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 0029927153 scopus 로고    scopus 로고
    • Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor α chain
    • Caput D, Laurent P, Kaghad M, et al. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor α chain. J Biol Chem. 1996;271:16921-16926.
    • (1996) J Biol Chem , vol.271 , pp. 16921-16926
    • Caput, D.1    Laurent, P.2    Kaghad, M.3
  • 2
    • 0032167603 scopus 로고    scopus 로고
    • The murine IL-13 receptor α2: Molecular cloning, characterization, and comparison with murine IL-13 receptor α1
    • Donaldson DD, Whitters MJ, Fitz LJ, et al. The murine IL-13 receptor α2: molecular cloning, characterization, and comparison with murine IL-13 receptor α1. J Immunol. 1998;161:2317-2324.
    • (1998) J Immunol , vol.161 , pp. 2317-2324
    • Donaldson, D.D.1    Whitters, M.J.2    Fitz, L.J.3
  • 3
    • 0031036961 scopus 로고    scopus 로고
    • Human ovarian carcinoma cell lines express IL-4 and IL-13 receptors: Comparison between IL-4- and IL-13-induced signal transduction
    • Murata T, Obiri NI, Debinski W, et al. Human ovarian carcinoma cell lines express IL-4 and IL-13 receptors: comparison between IL-4- and IL-13-induced signal transduction. Int J Cancer. 1997;70:230-240.
    • (1997) Int J Cancer , vol.70 , pp. 230-240
    • Murata, T.1    Obiri, N.I.2    Debinski, W.3
  • 4
    • 0034162718 scopus 로고    scopus 로고
    • IL-13 receptor α chain: A novel tumor associated transmembrane protein in primary explants of human malignant gliomas
    • Joshi BH, Plautz GE, Puri RK. IL-13 receptor α chain: a novel tumor associated transmembrane protein in primary explants of human malignant gliomas. Cancer Res. 2000;60:1168-1172.
    • (2000) Cancer Res , vol.60 , pp. 1168-1172
    • Joshi, B.H.1    Plautz, G.E.2    Puri, R.K.3
  • 5
    • 0034210937 scopus 로고    scopus 로고
    • Interleukin-13 fusion cytotoxin as a potent targeted agent for AIDS-Kaposi's sarcoma xenograft
    • Husain SR, Puri RK. Interleukin-13 fusion cytotoxin as a potent targeted agent for AIDS-Kaposi's sarcoma xenograft. Blood. 2000;95:3506-3513.
    • (2000) Blood , vol.95 , pp. 3506-3513
    • Husain, S.R.1    Puri, R.K.2
  • 6
    • 0033868052 scopus 로고    scopus 로고
    • Interleukin-13 sensitivity and receptor phenotypes of human glial cell lines: Non-neoplastic glia and low-grade astrocytoma differ from malignant glioma
    • Liu H, Jacobs BS, Liu J, et al. Interleukin-13 sensitivity and receptor phenotypes of human glial cell lines: non-neoplastic glia and low-grade astrocytoma differ from malignant glioma. Cancer Immunol Immunother. 2000;49:319-324.
    • (2000) Cancer Immunol Immunother , vol.49 , pp. 319-324
    • Liu, H.1    Jacobs, B.S.2    Liu, J.3
  • 7
    • 0035881289 scopus 로고    scopus 로고
    • Interleukin-13 receptor-targeted cancer therapy in an immunodeficient animal model of human head and neck cancer
    • Kawakami K, Kawakami M, Joshi BH, et al. Interleukin-13 receptor-targeted cancer therapy in an immunodeficient animal model of human head and neck cancer. Cancer Res. 2001;61:6194-6200.
    • (2001) Cancer Res , vol.61 , pp. 6194-6200
    • Kawakami, K.1    Kawakami, M.2    Joshi, B.H.3
  • 8
    • 0034585303 scopus 로고    scopus 로고
    • Mutation and functional analysis of IL-13 receptors in human malignant glioma cells
    • Kawakami M, Leland P, Kawakami K, et al. Mutation and functional analysis of IL-13 receptors in human malignant glioma cells. Oncol Res. 2001;12:459-467.
    • (2001) Oncol Res , vol.12 , pp. 459-467
    • Kawakami, M.1    Leland, P.2    Kawakami, K.3
  • 9
    • 0347594130 scopus 로고    scopus 로고
    • Interleukin-13 receptor α2 chain in human head and neck cancer serves as a unique diagnostic marker
    • Kawakami M, Kawakami K, Kasperbauer JL, et al. Interleukin-13 receptor α2 chain in human head and neck cancer serves as a unique diagnostic marker. Clin Cancer Res. 2003;9:6381-6388.
    • (2003) Clin Cancer Res , vol.9 , pp. 6381-6388
    • Kawakami, M.1    Kawakami, K.2    Kasperbauer, J.L.3
  • 10
    • 4143080435 scopus 로고    scopus 로고
    • Analysis of interleukin-13 receptor α2 expression in human pediatric brain tumors
    • Kawakami M, Kawakami K, Takahashi S, et al. Analysis of interleukin-13 receptor α2 expression in human pediatric brain tumors. Cancer. 2004;101:1036-1042.
    • (2004) Cancer , vol.101 , pp. 1036-1042
    • Kawakami, M.1    Kawakami, K.2    Takahashi, S.3
  • 11
    • 10744229896 scopus 로고    scopus 로고
    • The negative-feedback regulation of the IL-13 signal by the IL-13 receptor α2 chain in bronchial epithelial cells
    • Yasunaga S, Yuyama N, Arima K, et al. The negative-feedback regulation of the IL-13 signal by the IL-13 receptor α2 chain in bronchial epithelial cells. Cytokine. 2003;24:293-303.
    • (2003) Cytokine , vol.24 , pp. 293-303
    • Yasunaga, S.1    Yuyama, N.2    Arima, K.3
  • 12
    • 0031903791 scopus 로고    scopus 로고
    • Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathway
    • Murata T, Husain SR, Mohri H, et al. Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathway. Int Immunol. 1998;10:1103-1110.
    • (1998) Int Immunol , vol.10 , pp. 1103-1110
    • Murata, T.1    Husain, S.R.2    Mohri, H.3
  • 13
    • 0041427695 scopus 로고    scopus 로고
    • Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells
    • Jakubzick C, Choi ES, Joshi BH, et al. Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells. J Immunol. 2003;171:2684-2693.
    • (2003) J Immunol , vol.171 , pp. 2684-2693
    • Jakubzick, C.1    Choi, E.S.2    Joshi, B.H.3
  • 14
    • 2442704310 scopus 로고    scopus 로고
    • Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia
    • Jakubzick C, Choi ES, Carpenter KJ, et al. Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia. Am J Pathol. 2004;164:1989-2001.
    • (2004) Am J Pathol , vol.164 , pp. 1989-2001
    • Jakubzick, C.1    Choi, E.S.2    Carpenter, K.J.3
  • 15
    • 0032009864 scopus 로고    scopus 로고
    • Structure of and signal transduction through interleukin 4 and interleukin 13 receptors
    • Murata T, Obiri NI, Puri RK. Structure of and signal transduction through interleukin 4 and interleukin 13 receptors. Int J Mol Med. 1998;1:551-557.
    • (1998) Int J Mol Med , vol.1 , pp. 551-557
    • Murata, T.1    Obiri, N.I.2    Puri, R.K.3
  • 16
    • 0038517976 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13 signaling connections maps
    • Kelly-Welch AE, Hanson EM, Boothby MR, et al. Interleukin-4 and interleukin-13 signaling connections maps. Science. 2003;300:1527-1528.
    • (2003) Science , vol.300 , pp. 1527-1528
    • Kelly-Welch, A.E.1    Hanson, E.M.2    Boothby, M.R.3
  • 17
    • 0035353154 scopus 로고    scopus 로고
    • The interleukin-13 receptor α2 chain: An essential component for binding and internalization but not for IL-13 induced signal transduction through STAT6 pathway
    • Kawakami K, Taguchi J, Murata T, et al. The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for IL-13 induced signal transduction through STAT6 pathway. Blood. 2001;97:2673-2679.
    • (2001) Blood , vol.97 , pp. 2673-2679
    • Kawakami, K.1    Taguchi, J.2    Murata, T.3
  • 18
    • 0032525073 scopus 로고    scopus 로고
    • Interleukin-13 receptor α′ chain but not α chain: A functional component of interleukin-4 receptor
    • Murata T, Taguchi J, Puri RK. Interleukin-13 receptor α′ chain but not α chain: a functional component of interleukin-4 receptor. Blood. 1998;91:3884-3891.
    • (1998) Blood , vol.91 , pp. 3884-3891
    • Murata, T.1    Taguchi, J.2    Puri, R.K.3
  • 19
    • 0344091551 scopus 로고    scopus 로고
    • Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor α2
    • Wood N, Whitters MJ, Jacobson BA, et al. Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor α2. J Exp Med. 2003;197:703-709.
    • (2003) J Exp Med , vol.197 , pp. 703-709
    • Wood, N.1    Whitters, M.J.2    Jacobson, B.A.3
  • 20
    • 0035816669 scopus 로고    scopus 로고
    • Identification of distinct roles for a dileucine and a tyrosine internalization motif in the interleukin-13 binding component IL-13 receptor α2 chain
    • Kawakami K, Takeshita F, Puri RK. Identification of distinct roles for a dileucine and a tyrosine internalization motif in the interleukin-13 binding component IL-13 receptor α2 chain. J Biol Chem. 2001;276:25114-25120.
    • (2001) J Biol Chem , vol.276 , pp. 25114-25120
    • Kawakami, K.1    Takeshita, F.2    Puri, R.K.3
  • 21
    • 0030975719 scopus 로고    scopus 로고
    • Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned 11-13 receptor and 11-4 receptor alpha-chains
    • Zhang JG, Hilton DJ, Willson TA, et al. Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned 11-13 receptor and 11-4 receptor alpha-chains. J Biol Chem. 1997;272:9474-9480.
    • (1997) J Biol Chem , vol.272 , pp. 9474-9480
    • Zhang, J.G.1    Hilton, D.J.2    Willson, T.A.3
  • 22
    • 0034804510 scopus 로고    scopus 로고
    • Expression of interleukin 13 receptor in glioma and renal cell carcinoma: IL13Rα2 as a decoy receptor for IL13
    • Bernard J, Treton D, Vermot-Desroches C, et al. Expression of interleukin 13 receptor in glioma and renal cell carcinoma: IL13Rα2 as a decoy receptor for IL13. Lab Invest. 2001;81:1223-1231.
    • (2001) Lab Invest , vol.81 , pp. 1223-1231
    • Bernard, J.1    Treton, D.2    Vermot-Desroches, C.3
  • 23
    • 0032545213 scopus 로고    scopus 로고
    • Interleukin-13: Central mediator of allergic asthma
    • Wills-Karp M, Luyimbazi J, Xu X, et al. Interleukin-13: central mediator of allergic asthma. Science. 1998;282:2258-2261.
    • (1998) Science , vol.282 , pp. 2258-2261
    • Wills-Karp, M.1    Luyimbazi, J.2    Xu, X.3
  • 24
    • 0036168305 scopus 로고    scopus 로고
    • IL-13Rα2, a decoy receptor for IL-13 act as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells
    • Rahaman SO, Sharma P, Harbor PC, et al. IL-13Rα2, a decoy receptor for IL-13 act as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells. Cancer Res. 2002;62:1103-1109.
    • (2002) Cancer Res , vol.62 , pp. 1103-1109
    • Rahaman, S.O.1    Sharma, P.2    Harbor, P.C.3
  • 25
    • 0037780812 scopus 로고    scopus 로고
    • Functional characterization of IL-13 receptor α2 gene promoter: A critical role of the transcription factor STAT6 for regulated expression
    • David MD, Bertoglio J, Pierre J. Functional characterization of IL-13 receptor α2 gene promoter: a critical role of the transcription factor STAT6 for regulated expression. Oncogene. 2003;22:3386-3394.
    • (2003) Oncogene , vol.22 , pp. 3386-3394
    • David, M.D.1    Bertoglio, J.2    Pierre, J.3
  • 26
    • 0035845855 scopus 로고    scopus 로고
    • Induction of the IL-13 receptor α2-chain by IL-4 and IL-13 in human keratinocytes: Involvement of STAT6, ERK and p38 MAPK pathways
    • David M, Ford D, Bertoglio J, et al. Induction of the IL-13 receptor α2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways. Oncogene. 2001;20;6660-6668.
    • (2001) Oncogene , vol.20 , pp. 6660-6668
    • David, M.1    Ford, D.2    Bertoglio, J.3
  • 27
    • 0035905491 scopus 로고    scopus 로고
    • In vivo over-expression of IL-13 receptor α2 chain inhibits tumorigenicity of human breast and pancreatic tumors in immunodeficient mice
    • Kawakami K, Kawakami M, Snoy PJ, et al. in vivo over-expression of IL-13 receptor α2 chain inhibits tumorigenicity of human breast and pancreatic tumors in immunodeficient mice. J Exp Med. 2001;194:1743-1754.
    • (2001) J Exp Med , vol.194 , pp. 1743-1754
    • Kawakami, K.1    Kawakami, M.2    Snoy, P.J.3
  • 28
    • 0034569025 scopus 로고    scopus 로고
    • NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
    • Terabe M, Matsui S, Noben-Trauth N, et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat Immunol. 2000;1:515-520.
    • (2000) Nat Immunol , vol.1 , pp. 515-520
    • Terabe, M.1    Matsui, S.2    Noben-Trauth, N.3
  • 29
    • 10744220561 scopus 로고    scopus 로고
    • Transforming growth factor-β production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence
    • Terabe M, Matsui S, Park JM, et al. Transforming growth factor-β production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med. 2003;198:1741-1752.
    • (2003) J Exp Med , vol.198 , pp. 1741-1752
    • Terabe, M.1    Matsui, S.2    Park, J.M.3
  • 30
    • 0029101822 scopus 로고
    • Experimental gene therapy of cancer using tumor cells engineered to secrete interleukin-13
    • Lebel-Binay S, Laguerre B, Quintin-Colonna F, et al. Experimental gene therapy of cancer using tumor cells engineered to secrete interleukin-13. Eur J Immunol. 1995;25:2340-2348.
    • (1995) Eur J Immunol , vol.25 , pp. 2340-2348
    • Lebel-Binay, S.1    Laguerre, B.2    Quintin-Colonna, F.3
  • 31
    • 3242687198 scopus 로고    scopus 로고
    • Tumor cells secreting IL-13 but not IL-13Rα2 fusion protein have reduced tumorigenicity in vivo
    • Ma HL, Whitters MJ, Jacobson BA, et al. Tumor cells secreting IL-13 but not IL-13Rα2 fusion protein have reduced tumorigenicity in vivo. Int Immunol. 2004;16:1009-1017.
    • (2004) Int Immunol , vol.16 , pp. 1009-1017
    • Ma, H.L.1    Whitters, M.J.2    Jacobson, B.A.3
  • 32
    • 0029041783 scopus 로고
    • A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4
    • Debinski W, Obiri NI, Pastan I, et al. A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4. J Biol Chem. 1995;270:16775-16780.
    • (1995) J Biol Chem , vol.270 , pp. 16775-16780
    • Debinski, W.1    Obiri, N.I.2    Pastan, I.3
  • 33
    • 0036284481 scopus 로고    scopus 로고
    • Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: Differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin
    • Joshi BH, Kawakami K, Leland P, et al. Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin. Clin Cancer Res. 2002;8:1948-1956.
    • (2002) Clin Cancer Res , vol.8 , pp. 1948-1956
    • Joshi, B.H.1    Kawakami, K.2    Leland, P.3
  • 34
    • 4644221708 scopus 로고    scopus 로고
    • Analysis of antitumor activity of an IL-13 receptor-targeted cytotoxin composed of IL-13 antagonist and Pseudomonas exotoxin
    • Kioi M, Kawakami K, Puri RK. Analysis of antitumor activity of an IL-13 receptor-targeted cytotoxin composed of IL-13 antagonist and Pseudomonas exotoxin. Clin Cancer Res. 2004;10:6231-6238.
    • (2004) Clin Cancer Res , vol.10 , pp. 6231-6238
    • Kioi, M.1    Kawakami, K.2    Puri, R.K.3
  • 35
    • 0029934957 scopus 로고    scopus 로고
    • Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR)
    • Puri RK, Leland P, Obiri NI, et al. Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR). Blood. 1996;87:4333-4339.
    • (1996) Blood , vol.87 , pp. 4333-4339
    • Puri, R.K.1    Leland, P.2    Obiri, N.I.3
  • 36
    • 4143115725 scopus 로고    scopus 로고
    • Interleukin-13 and cancer
    • Brombacher F, ed. Georgetown, TX: Landes Bioscience
    • Kawakami K, Puri RK. Interleukin-13 and cancer. In: Brombacher F, ed. Interleukin-13. Georgetown, TX: Landes Bioscience, 2003:65-78.
    • (2003) Interleukin-13 , pp. 65-78
    • Kawakami, K.1    Puri, R.K.2
  • 37
    • 0036705806 scopus 로고    scopus 로고
    • Improved anti-tumor activity and safety of interleukin-13 receptor targeted cytotoxin by systemic continuous administration in head and neck cancer xenograft model
    • Kawakami K, Husain SR, Kawakami M, et al. Improved anti-tumor activity and safety of interleukin-13 receptor targeted cytotoxin by systemic continuous administration in head and neck cancer xenograft model. Mol Med. 2002;8:487-492.
    • (2002) Mol Med , vol.8 , pp. 487-492
    • Kawakami, K.1    Husain, S.R.2    Kawakami, M.3
  • 38
    • 0035871986 scopus 로고    scopus 로고
    • Interleulin-13 receptor as a unique target for anti-glioblastoma therapy
    • Husain SR, Joshi BH, Puri RK. Interleulin-13 receptor as a unique target for anti-glioblastoma therapy. Int J Cancer. 2001;92:168-175.
    • (2001) Int J Cancer , vol.92 , pp. 168-175
    • Husain, S.R.1    Joshi, B.H.2    Puri, R.K.3
  • 39
    • 0038805154 scopus 로고    scopus 로고
    • Intratumoral administration of interleukin 13 receptor-targeted cytotoxin induces apoptotic cell death in human malignant glioma tumor xenografts
    • Kawakami M, Kawakami K, Puri RK. Intratumoral administration of interleukin 13 receptor-targeted cytotoxin induces apoptotic cell death in human malignant glioma tumor xenografts. Mol Cancer Ther. 2002;1:999-1007.
    • (2002) Mol Cancer Ther , vol.1 , pp. 999-1007
    • Kawakami, M.1    Kawakami, K.2    Puri, R.K.3
  • 40
    • 0028178981 scopus 로고
    • A circularly permuted recombinant interleukin 4 toxin with increased activity
    • Kreitman RJ, Puri RK, Pastan I. A circularly permuted recombinant interleukin 4 toxin with increased activity. Proc Natl Acad Sci USA. 1994;91:6889-6893.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6889-6893
    • Kreitman, R.J.1    Puri, R.K.2    Pastan, I.3
  • 41
    • 0029135360 scopus 로고
    • Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma
    • Kreitman RJ, Puri RK, Pastan I. Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma. Cancer Res. 1995;55:3357-3363.
    • (1995) Cancer Res , vol.55 , pp. 3357-3363
    • Kreitman, R.J.1    Puri, R.K.2    Pastan, I.3
  • 42
    • 0030760143 scopus 로고    scopus 로고
    • Improved DNA:liposome complexes for increased systemic delivery and gene expression
    • Templeton NS, Lasic DD, Frederik PM, et al. Improved DNA:liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol. 1997;15:647-652.
    • (1997) Nat Biotechnol , vol.15 , pp. 647-652
    • Templeton, N.S.1    Lasic, D.D.2    Frederik, P.M.3
  • 43
    • 0038262659 scopus 로고    scopus 로고
    • Potent antitumor activity of IL-13 cytotoxin in human pancreatic tumors engineered to express IL-13 receptor α2 chain in vivo
    • Kawakami K, Kawakami M, Husain SR, et al. Potent antitumor activity of IL-13 cytotoxin in human pancreatic tumors engineered to express IL-13 receptor α2 chain in vivo. Gene Ther. 2003;10:1116-1128.
    • (2003) Gene Ther , vol.10 , pp. 1116-1128
    • Kawakami, K.1    Kawakami, M.2    Husain, S.R.3
  • 44
    • 0037114188 scopus 로고    scopus 로고
    • Interleukin-13 receptor-targeted cytotoxin cancer therapy leads to complete eradication of tumors with the aid of phagocytic cells in nude mice model of human cancer
    • Kawakami K, Kawakami M, Puri RK. Interleukin-13 receptor-targeted cytotoxin cancer therapy leads to complete eradication of tumors with the aid of phagocytic cells in nude mice model of human cancer. J Immunol. 2002;169:7119-7126.
    • (2002) J Immunol , vol.169 , pp. 7119-7126
    • Kawakami, K.1    Kawakami, M.2    Puri, R.K.3
  • 45
    • 4143113057 scopus 로고    scopus 로고
    • Specifically targeted killing of interleukin-13 receptor-expressing breast cancer by IL-13 fusion cytotoxin in animal model of human disease
    • Kawakami K, Kawakami M, Puri RK. Specifically targeted killing of interleukin-13 receptor-expressing breast cancer by IL-13 fusion cytotoxin in animal model of human disease. Mol Cancer Ther. 2004;3:137-147.
    • (2004) Mol Cancer Ther , vol.3 , pp. 137-147
    • Kawakami, K.1    Kawakami, M.2    Puri, R.K.3
  • 46
    • 0345183090 scopus 로고    scopus 로고
    • Phase I/II study: Intratumoral infusion of IL13-PE38QQR cytotoxin for recurrent supratentorial malignant glioma
    • Weingart J, Strauss LC, Grossman SA, et al. Phase I/II study: intratumoral infusion of IL13-PE38QQR cytotoxin for recurrent supratentorial malignant glioma. Neuro-oncol. 2002;4:379.
    • (2002) Neuro-oncol , vol.4 , pp. 379
    • Weingart, J.1    Strauss, L.C.2    Grossman, S.A.3
  • 47
    • 0042350971 scopus 로고    scopus 로고
    • A clinical study of convection-enhanced delivery of IL13-PE38QQR cytotoxin pre- and post-resection of recurrent GBM
    • Chicago, abstract
    • Lang F, Kunwar S, Strauss L, et al. A clinical study of convection-enhanced delivery of IL13-PE38QQR cytotoxin pre- and post-resection of recurrent GBM. 70th annual meeting of the American Association of Neurological Surgeons, Chicago, 2002 (abstract).
    • (2002) 70th Annual Meeting of the American Association of Neurological Surgeons
    • Lang, F.1    Kunwar, S.2    Strauss, L.3
  • 48
    • 4143048716 scopus 로고    scopus 로고
    • Pre-operative infusion of IL13-PE38QQR cytotoxin by convection-enhanced delivery (CED) in recurrent malignant glioma: A phase I/II study
    • abstract
    • Ram Z, Barnett G, Vogelbaum M, et al. Pre-operative infusion of IL13-PE38QQR cytotoxin by convection-enhanced delivery (CED) in recurrent malignant glioma: a phase I/II study. American Society of Clinical Oncology annual meeting, 2003 (abstract).
    • (2003) American Society of Clinical Oncology Annual Meeting
    • Ram, Z.1    Barnett, G.2    Vogelbaum, M.3
  • 49
    • 23444437213 scopus 로고
    • Convection-enhanced delivery to macromolecules in the brain
    • Bobo RH, Laske DW, Akbasak A, et al. Convection-enhanced delivery to macromolecules in the brain. Proc Natl Acad Sci USA. 1994;91:2076-2080.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2076-2080
    • Bobo, R.H.1    Laske, D.W.2    Akbasak, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.