Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy

Molecular Therapy

Volumn 22, Issue 8, 2014, Pages 1423-1433

  Relizani, Karima ^a,b,c   Mouisel, Etienne ^a,d   Giannesini, Benoit ^e   Hourdé, Christophe ^a   Patel, Ketan ^f   Morales Gonzalez, Susanne ^b   Jülich, Kristina ^b   Vignaud, Alban ^a,g   Piétri Rouxel, France ^a   Fortin, Dominique ^h   Garcia, Luis ^c   Blot, Stéphane ⁱ   Ritvos, Olli ^j   Bendahan, David ^e   Ferry, Arnaud ^a,k   Ventura Clapier, Renée ^h   Schuelke, Markus ^b   Amthor, Helge ^a,c,l  

^a SORBONNE UNIVERSITÉ   (France)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^d Université de Toulouse   (France)

^e University of Aix Marseille   (France)

^f UNIVERSITY OF READING   (United Kingdom)

^g GÉNÉTHON   (France)

^h Universite Paris Sud   (France)

ⁱ UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^j UNIVERSITY OF HELSINKI   (Finland)

^k UNIVERSITÉ PARIS DESCARTES   (France)

^l HÔPITAL NECKER ENFANTS MALADES   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR 2B; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CYTOKINE RECEPTOR ANTAGONIST; LACTIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PORIN; PYRUVATE DEHYDROGENASE KINASE 4; SOLUBLE ACTIVIN RECEPTOR 2B IMMUNOGLOBULIN FC FRAGMENT FUSION PROTEIN; UNCLASSIFIED DRUG; ACTIVIN RECEPTOR TYPE II-B; IMMUNOGLOBULIN FC FRAGMENT;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DUCHENNE MUSCULAR DYSTROPHY; ENERGY METABOLISM; EXTRACELLULAR MATRIX; GENE; HUMAN; HUMAN CELL; IN VIVO STUDY; LACTATE BLOOD LEVEL; MALE; MDX GENE; METABOLIC DISORDER; METABOLIC MYOPATHY; METABOLIC STRESS; MITOCHONDRIAL MEMBRANE; MOUSE; MUSCLE FATIGUE; MUSCLE METABOLISM; MYOPATHY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; ANIMAL; ANIMAL MUSCULAR DYSTROPHY; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; MUSCLE; PATHOPHYSIOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALIA; MUS;

ACTIVIN RECEPTORS, TYPE II; ANIMALS; CELL LINE; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; MALE; MICE; MICE, INBRED MDX; MUSCLES; MUSCULAR DYSTROPHY, ANIMAL; PORINS; SIGNAL TRANSDUCTION;

EID: 84905489829     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.90     Document Type: Article

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