메뉴 건너뛰기




Volumn 38, Issue 11, 2013, Pages 2286-2296

BDNF overexpression in the ventral tegmental area prolongs social defeat stress-induced cross-sensitization to amphetamine and increases ΔfosB expression in mesocorticolimbic regions of rats

Author keywords

Amphetamine; BDNF; cross sensitization; DFosB; Social defeat; VTA

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DEXAMPHETAMINE; PARVOVIRUS VECTOR; TRANSCRIPTION FACTOR DELTA FOSB;

EID: 84884291981     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.130     Document Type: Article
Times cited : (31)

References (55)
  • 1
    • 0026482150 scopus 로고
    • Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo
    • Altar CA, Boylan CB, Jackson C, Hershenson S, Miller J, Wiegand SJ et al (1992). Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo. Proc Natl Acad Sci USA 89: 11347-11351.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11347-11351
    • Altar, C.A.1    Boylan, C.B.2    Jackson, C.3    Hershenson, S.4    Miller, J.5    Wiegand, S.J.6
  • 2
    • 0018874396 scopus 로고
    • Interchangeability of stress and amphetamine in sensitization
    • Antelman SM, Eichler AJ, Black CA, Kocan D (1980). Interchangeability of stress and amphetamine in sensitization. Science 207: 329-331.
    • (1980) Science , vol.207 , pp. 329-331
    • Antelman, S.M.1    Eichler, A.J.2    Black, C.A.3    Kocan, D.4
  • 3
    • 21544446985 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta
    • Baquet ZC, Bickford PC, Jones KR (2005). Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. J Neurosci 25: 6251-6259.
    • (2005) J Neurosci , vol.25 , pp. 6251-6259
    • Baquet, Z.C.1    Bickford, P.C.2    Jones, K.R.3
  • 5
    • 32444451651 scopus 로고    scopus 로고
    • Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    • Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ et al (2006). Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311: 864-868.
    • (2006) Science , vol.311 , pp. 864-868
    • Berton, O.1    McClung, C.A.2    Dileone, R.J.3    Krishnan, V.4    Renthal, W.5    Russo, S.J.6
  • 6
    • 0029809424 scopus 로고    scopus 로고
    • Neurotrophins stimulate the release of dopamine from rat mesencephalic neurons via Trk and p75Lntr receptors
    • Blochl A, Sirrenberg C (1996). Neurotrophins stimulate the release of dopamine from rat mesencephalic neurons via Trk and p75Lntr receptors. J Biol Chem 271: 21100-21107.
    • (1996) J Biol Chem , vol.271 , pp. 21100-21107
    • Blochl, A.1    Sirrenberg, C.2
  • 7
    • 18144438661 scopus 로고    scopus 로고
    • Neurotrophic mechanisms in drug addiction
    • Bolanos CA, Nestler EJ (2004). Neurotrophic mechanisms in drug addiction. Neuromol Med 5: 69-83.
    • (2004) Neuromol Med , vol.5 , pp. 69-83
    • Bolanos, C.A.1    Nestler, E.J.2
  • 8
    • 0032826101 scopus 로고    scopus 로고
    • D-amphetamineinduced behavioral sensitization: Implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation
    • Cador M, Bjijou Y, Cailhol S, Stinus L (1999). D-amphetamineinduced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation. Neuroscience 94: 705-721.
    • (1999) Neuroscience , vol.94 , pp. 705-721
    • Cador, M.1    Bjijou, Y.2    Cailhol, S.3    Stinus, L.4
  • 9
    • 26844482700 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males
    • Cheng C-Y, Hong C-J, Yu YWY, Chen T-J, Wu H-C, Tsai S-J (2005). Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males. Mol Brain Res 140: 86-90.
    • (2005) Mol Brain Res , vol.140 , pp. 86-90
    • Cheng, C.-Y.1    Hong, C.-J.2    Yu, Y.W.Y.3    Chen, T.-J.4    Wu, H.-C.5    Tsai, S.-J.6
  • 10
    • 77949700751 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor and the development of structural neuronal connectivity
    • Cohen-Cory S, Kidane AH, Shirkey NJ, Marshak S (2010). Brainderived neurotrophic factor and the development of structural neuronal connectivity. Dev Neurobiol 70: 271-288.
    • (2010) Dev Neurobiol , vol.70 , pp. 271-288
    • Cohen-Cory, S.1    Kidane, A.H.2    Shirkey, N.J.3    Marshak, S.4
  • 11
    • 0035211697 scopus 로고    scopus 로고
    • Repeated socialdefeat stress, cocaine or morphine. Effects on behavioral sensitization and intravenous cocaine self-administration 'binges'
    • Covington HE 3rd, Miczek KA (2001). Repeated socialdefeat stress, cocaine or morphine. Effects on behavioral sensitization and intravenous cocaine self-administration 'binges'. Psychopharmacology (Berl) 158: 388-398.
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 388-398
    • Covington III, H.E.1    Miczek, K.A.2
  • 14
    • 0028281816 scopus 로고
    • Social isolationinduced enhancement of the psychomotor effects of morphine depends on corticosterone secretion
    • Deroche V, Piazza PV, Le Moal M, Simon H (1994). Social isolationinduced enhancement of the psychomotor effects of morphine depends on corticosterone secretion. Brain Res 640: 136-139.
    • (1994) Brain Res , vol.640 , pp. 136-139
    • Deroche, V.1    Piazza, P.V.2    Le Moal, M.3    Simon, H.4
  • 15
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G, Imperato A (1988). Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85: 5274-5278.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 16
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A et al (2003). The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112: 257-269.
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3    Goldberg, T.E.4    Kolachana, B.S.5    Bertolino, A.6
  • 17
    • 77951298810 scopus 로고    scopus 로고
    • Short- and longterm effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions
    • Fanous S, Hammer RP Jr, Nikulina EM (2010). Short- and longterm effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience 167: 598-607.
    • (2010) Neuroscience , vol.167 , pp. 598-607
    • Fanous, S.1    Hammer Jr., R.P.2    Nikulina, E.M.3
  • 18
    • 80052343534 scopus 로고    scopus 로고
    • Viral depletion of VTA BDNF in rats modulates social behavior, consequences of intermittent social defeat stress, and long-term weight regulation
    • Fanous S, Terwilliger EF, Hammer RP Jr, Nikulina EM (2011). Viral depletion of VTA BDNF in rats modulates social behavior, consequences of intermittent social defeat stress, and long-term weight regulation. Neurosci Lett 502: 192-196.
    • (2011) Neurosci Lett , vol.502 , pp. 192-196
    • Fanous, S.1    Terwilliger, E.F.2    Hammer Jr., R.P.3    Nikulina, E.M.4
  • 19
    • 33748948061 scopus 로고    scopus 로고
    • An association study of the brain-derived neurotrophic factor Val66Met polymorphism and amphetamine response
    • Flanagin BA, Cook EH Jr, de Wit H (2006). An association study of the brain-derived neurotrophic factor Val66Met polymorphism and amphetamine response. Am J Med Genet Part B Neuropsychiatr Genet 141B: 576-583.
    • (2006) Am J Med Genet Part B Neuropsychiatr Genet , vol.141 B , pp. 576-583
    • Flanagin, B.A.1    Cook Jr., E.H.2    De Wit, H.3
  • 21
    • 0023502592 scopus 로고
    • Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in rats
    • Geyer MA, Russo PV, Segal DS, Kuczenski R (1987). Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in rats. Pharmacol Biochem Behav 28: 393-399.
    • (1987) Pharmacol Biochem Behav , vol.28 , pp. 393-399
    • Geyer, M.A.1    Russo, P.V.2    Segal, D.S.3    Kuczenski, R.4
  • 23
    • 0033562567 scopus 로고    scopus 로고
    • Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor
    • Horger BA, Iyasere CA, Berhow MT, Messer CJ, Nestler EJ, Taylor JR (1999). Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. J Neurosci 19: 4110-4122.
    • (1999) J Neurosci , vol.19 , pp. 4110-4122
    • Horger, B.A.1    Iyasere, C.A.2    Berhow, M.T.3    Messer, C.J.4    Nestler, E.J.5    Taylor, J.R.6
  • 24
    • 0024338263 scopus 로고
    • Stress-induced enhancement of dopamine and acetylcholine release in limbic structures: Role of corticosterone
    • Imperato A, Puglisi-Allegra S, Casolini P, Zocchi A, Angelucci L (1989). Stress-induced enhancement of dopamine and acetylcholine release in limbic structures: role of corticosterone. Eur J Pharmacology 165: 337-338.
    • (1989) Eur J Pharmacology , vol.165 , pp. 337-338
    • Imperato, A.1    Puglisi-Allegra, S.2    Casolini, P.3    Zocchi, A.4    Angelucci, L.5
  • 25
    • 0001042729 scopus 로고
    • The circuitry mediating the translation of motivational stimuli into adaptive motor responses
    • Kalivas PWBarnes CD (eds)., CRC Press: Boca Raton, FL, USA
    • Kalivas PW, Churchill L, Klitenick MA (1993). The circuitry mediating the translation of motivational stimuli into adaptive motor responses. In: Kalivas PWBarnes CD (eds). Limbic Motor Circuits and Neuropsychiatry. CRC Press: Boca Raton, FL, USA, pp 237-288.
    • (1993) Limbic Motor Circuits and Neuropsychiatry , pp. 237-288
    • Kalivas, P.W.1    Churchill, L.2    Klitenick, M.A.3
  • 26
    • 0025751604 scopus 로고
    • Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity
    • Kalivas PW, Stewart J (1991). Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res Rev 16: 223-244.
    • (1991) Brain Res Rev , vol.16 , pp. 223-244
    • Kalivas, P.W.1    Stewart, J.2
  • 27
    • 0033575937 scopus 로고    scopus 로고
    • Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine
    • KelzMB, Chen J, CarlezonWA Jr,Whisler K, Gilden L, Beckmann AM et al (1999). Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature 401: 272-276.
    • (1999) Nature , vol.401 , pp. 272-276
    • Kelz, M.B.1    Chen, J.2    Carlezon Jr., W.A.3    Whisler, K.4    Gilden, L.5    Beckmann, A.M.6
  • 28
    • 0032051603 scopus 로고    scopus 로고
    • Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adenoassociated virus vectors
    • Klein RL, Meyer EM, Peel AL, Zolotukhin S, Meyers C, Muzyczka N et al (1998). Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adenoassociated virus vectors. Exp Neurol 150: 183-194.
    • (1998) Exp Neurol , vol.150 , pp. 183-194
    • Klein, R.L.1    Meyer, E.M.2    Peel, A.L.3    Zolotukhin, S.4    Meyers, C.5    Muzyczka, N.6
  • 29
    • 84872353394 scopus 로고    scopus 로고
    • Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance
    • Li X, Dejoseph MR, Urban JH, Bahi A, Dreyer JL, Meredith GE et al (2013). Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance. J Neurosci 33: 1130-1142.
    • (2013) J Neurosci , vol.33 , pp. 1130-1142
    • Li, X.1    Dejoseph, M.R.2    Urban, J.H.3    Bahi, A.4    Dreyer, J.L.5    Meredith, G.E.6
  • 30
    • 0033803065 scopus 로고    scopus 로고
    • Repeated stimulation of L-type calcium channels in the rat ventral tegmental area mimics the initiation of behavioral sensitization to cocaine
    • Licata SC, Freeman AY, Pierce-Bancroft AF, Pierce RC (2000). Repeated stimulation of L-type calcium channels in the rat ventral tegmental area mimics the initiation of behavioral sensitization to cocaine. Psychopharmacology (Berl) 152: 110-118.
    • (2000) Psychopharmacology (Berl) , vol.152 , pp. 110-118
    • Licata, S.C.1    Freeman, A.Y.2    Pierce-Bancroft, A.F.3    Pierce, R.C.4
  • 32
    • 1042277893 scopus 로고    scopus 로고
    • Aggression and defeat: Persistent effects on cocaine self-administration and gene expression in peptidergic and aminergic mesocorticolimbic circuits
    • Miczek KA, Covington HE 3rd, Nikulina EM Jr, Hammer RP (2004). Aggression and defeat: persistent effects on cocaine self-administration and gene expression in peptidergic and aminergic mesocorticolimbic circuits. Neurosci Biobehav Rev 27: 787-802.
    • (2004) Neurosci Biobehav Rev , vol.27 , pp. 787-802
    • Miczek, K.A.1    Covington III, H.E.2    Nikulina Jr., E.M.3    Hammer, R.P.4
  • 33
    • 0033011325 scopus 로고    scopus 로고
    • Behavioral sensitization to cocaine after a brief social defeat stress: C-fos expression in the PAG
    • Miczek KA, Nikulina E, Kream RM, Carter G, Espejo EF (1999). Behavioral sensitization to cocaine after a brief social defeat stress: c-fos expression in the PAG. Psychopharmacology (Berl) 141: 225-234.
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 225-234
    • Miczek, K.A.1    Nikulina, E.2    Kream, R.M.3    Carter, G.4    Espejo, E.F.5
  • 34
    • 79960043825 scopus 로고    scopus 로고
    • Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats
    • Miczek KA, Nikulina EM, Shimamoto A, Covington HE 3rd (2011). Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats. J Neurosci 31: 9848-9857.
    • (2011) J Neurosci , vol.31 , pp. 9848-9857
    • Miczek, K.A.1    Nikulina, E.M.2    Shimamoto, A.3    Covington III, H.E.4
  • 35
    • 0033578105 scopus 로고    scopus 로고
    • DeltaFosB: A molecular mediator of long-term neural and behavioral plasticity
    • Nestler EJ, Kelz MB, Chen J (1999). DeltaFosB: a molecular mediator of long-term neural and behavioral plasticity. Brain Res 835: 10-17.
    • (1999) Brain Res , vol.835 , pp. 10-17
    • Nestler, E.J.1    Kelz, M.B.2    Chen, J.3
  • 36
    • 42549132520 scopus 로고    scopus 로고
    • Long-lasting alteration in mesocorticolimbic structures after repeated social defeat stress in rats: Time course of muopioid receptor mRNA and FosB/DeltaFosB immunoreactivity
    • Nikulina EM, Arrillaga-Romany I, Miczek KA, Hammer RP Jr (2008). Long-lasting alteration in mesocorticolimbic structures after repeated social defeat stress in rats: time course of muopioid receptor mRNA and FosB/DeltaFosB immunoreactivity. Eur J Neurosci 27: 2272-2284.
    • (2008) Eur J Neurosci , vol.27 , pp. 2272-2284
    • Nikulina, E.M.1    Arrillaga-Romany, I.2    Miczek, K.A.3    Hammer Jr., R.P.4
  • 37
    • 1042272983 scopus 로고    scopus 로고
    • Long-term behavioral and neuronal crosssensitization to amphetamine induced by repeated brief social defeat stress: Fos in the ventral tegmental area and amygdala
    • Nikulina EM, Covington HE 3rd, Ganschow L, Hammer RP Jr, Miczek KA (2004). Long-term behavioral and neuronal crosssensitization to amphetamine induced by repeated brief social defeat stress: Fos in the ventral tegmental area and amygdala. Neuroscience 123: 857-865.
    • (2004) Neuroscience , vol.123 , pp. 857-865
    • Nikulina, E.M.1    Covington III, H.E.2    Ganschow, L.3    Hammer Jr., R.P.4    Miczek, K.A.5
  • 40
    • 0025239977 scopus 로고
    • Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration
    • Piazza PV, Deminiere JM, le Moal M, Simon H (1990). Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration. Brain Res 514: 22-26.
    • (1990) Brain Res , vol.514 , pp. 22-26
    • Piazza, P.V.1    Deminiere, J.M.2    Le Moal, M.3    Simon, H.4
  • 41
    • 0035001440 scopus 로고    scopus 로고
    • The role of neurotrophic factors in psychostimulant-induced behavioral and neuronal plasticity
    • Pierce RC, Bari AA (2001). The role of neurotrophic factors in psychostimulant-induced behavioral and neuronal plasticity. Rev Neurosci 12: 95-110.
    • (2001) Rev Neurosci , vol.12 , pp. 95-110
    • Pierce, R.C.1    Bari, A.A.2
  • 42
    • 33745740035 scopus 로고    scopus 로고
    • BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal
    • Pu L, Liu Q-s, Poo M-m (2006). BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal. Nat Neurosci 9: 605-607.
    • (2006) Nat Neurosci , vol.9 , pp. 605-607
    • Pu, L.1    Liu, Q.-S.2    Poo, M.-M.3
  • 43
    • 0022349489 scopus 로고
    • Sensitization to stress: The enduring effects of prior stress on amphetamine-induced rotational behavior
    • Robinson TE, Angus AL, Becker JB (1985). Sensitization to stress: the enduring effects of prior stress on amphetamine-induced rotational behavior. Life Sci 37: 1039-1042.
    • (1985) Life Sci , vol.37 , pp. 1039-1042
    • Robinson, T.E.1    Angus, A.L.2    Becker, J.B.3
  • 44
    • 0016248364 scopus 로고
    • Long-term administration of d-amphetamine: Progressive augmentation of motor activity and stereotypy
    • Segal DS, Mandell AJ (1974). Long-term administration of d-amphetamine: progressive augmentation of motor activity and stereotypy. Pharmacol Biochem Behav 2: 249-255.
    • (1974) Pharmacol Biochem Behav , vol.2 , pp. 249-255
    • Segal, D.S.1    Mandell, A.J.2
  • 45
    • 0032055648 scopus 로고    scopus 로고
    • Identification of a signaling pathway involved in calcium regulation of BDNF expression
    • Shieh PB, Hu SC, Bobb K, Timmusk T, Ghosh A (1998). Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20: 727-740.
    • (1998) Neuron , vol.20 , pp. 727-740
    • Shieh, P.B.1    Hu, S.C.2    Bobb, K.3    Timmusk, T.4    Ghosh, A.5
  • 46
    • 54949111686 scopus 로고    scopus 로고
    • Chronic stress, drug use, and vulnerability to addiction
    • Sinha R (2008). Chronic stress, drug use, and vulnerability to addiction. Ann NY Acad Sci 1141: 105-130.
    • (2008) Ann NY Acad Sci , vol.1141 , pp. 105-130
    • Sinha, R.1
  • 47
    • 0027326722 scopus 로고
    • Tolerance and sensitization to the behavioral effects of drugs
    • Stewart J, Badiani A (1993). Tolerance and sensitization to the behavioral effects of drugs. Behav Pharmacol 4: 289-312.
    • (1993) Behav Pharmacol , vol.4 , pp. 289-312
    • Stewart, J.1    Badiani, A.2
  • 48
    • 0020421621 scopus 로고
    • The projections of the ventral tegmental area and adjacent regions: A combined fluorescent retrograde tracer and immunofluorescence study in the rat
    • Swanson LW (1982). The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain Res Bull 9: 321-353.
    • (1982) Brain Res Bull , vol.9 , pp. 321-353
    • Swanson, L.W.1
  • 49
    • 0032034262 scopus 로고    scopus 로고
    • Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism
    • Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME (1998). Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron 20: 709-726.
    • (1998) Neuron , vol.20 , pp. 709-726
    • Tao, X.1    Finkbeiner, S.2    Arnold, D.B.3    Shaywitz, A.J.4    Greenberg, M.E.5
  • 50
    • 0030014575 scopus 로고    scopus 로고
    • Social defeat stress selectively alters mesocorticolimbic dopamine release: An in vivo microdialysis study
    • Tidey JW, Miczek KA (1996). Social defeat stress selectively alters mesocorticolimbic dopamine release: an in vivo microdialysis study. Brain Res 721: 140-149.
    • (1996) Brain Res , vol.721 , pp. 140-149
    • Tidey, J.W.1    Miczek, K.A.2
  • 51
    • 33845336449 scopus 로고    scopus 로고
    • Increased central brain-derived neurotrophic factor activity could be a risk factor for substance abuse: Implications for treatment
    • Tsai SJ (2007). Increased central brain-derived neurotrophic factor activity could be a risk factor for substance abuse: implications for treatment. Med Hypotheses 68: 410-414.
    • (2007) Med Hypotheses , vol.68 , pp. 410-414
    • Tsai, S.J.1
  • 52
    • 0035209299 scopus 로고    scopus 로고
    • Polysubstance abuse-vulnerability genes: Genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms
    • Uhl GR, Liu QR, Walther D, Hess J, Naiman D (2001). Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms. Am J Hum Genet 69: 1290-1300.
    • (2001) Am J Hum Genet , vol.69 , pp. 1290-1300
    • Uhl, G.R.1    Liu, Q.R.2    Walther, D.3    Hess, J.4    Naiman, D.5
  • 53
  • 54
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J, Samulski RJ (1998). Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 72: 2224-2232.
    • (1998) J Virol , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 55
    • 0033961676 scopus 로고    scopus 로고
    • An integrative neuroanatomical perspective on some subcortical substrates of adaptive responding with emphasis on the nucleus accumbens
    • Zahm DS (2000). An integrative neuroanatomical perspective on some subcortical substrates of adaptive responding with emphasis on the nucleus accumbens. Neurosci Biobehav Rev 24: 85-105.
    • (2000) Neurosci Biobehav Rev , vol.24 , pp. 85-105
    • Zahm, D.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.