메뉴 건너뛰기




Volumn 6, Issue 8, 2014, Pages 1090-1104

Macrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes

Author keywords

Autoimmunity; Beta cell; Diabetes; Innate; Neutrophil

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR4; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA;

EID: 84905409273     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201404144     Document Type: Review
Times cited : (63)

References (50)
  • 5
    • 57649221137 scopus 로고    scopus 로고
    • The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxis
    • Baugher PJ, Richmond A (2008) The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxis. J Biol Chem 283: 30868-30878
    • (2008) J Biol Chem , vol.283 , pp. 30868-30878
    • Baugher, P.J.1    Richmond, A.2
  • 6
  • 8
    • 70449704670 scopus 로고    scopus 로고
    • Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells
    • Bradshaw EM, Raddassi K, Elyaman W, Orban T, Gottlieb PA, Kent SC, Hafler DA (2009) Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells. J Immunol 183: 4432-4439
    • (2009) J Immunol , vol.183 , pp. 4432-4439
    • Bradshaw, E.M.1    Raddassi, K.2    Elyaman, W.3    Orban, T.4    Gottlieb, P.A.5    Kent, S.C.6    Hafler, D.A.7
  • 9
    • 0030995686 scopus 로고    scopus 로고
    • Treatment with neutralizing antibodies specific for IL-1beta prevents cyclophosphamide-induced diabetes in nonobese diabetic mice
    • Cailleau C, Diu-Hercend A, Ruuth E, Westwood R, Carnaud C (1997) Treatment with neutralizing antibodies specific for IL-1beta prevents cyclophosphamide-induced diabetes in nonobese diabetic mice. Diabetes 46: 937-940
    • (1997) Diabetes , vol.46 , pp. 937-940
    • Cailleau, C.1    Diu-Hercend, A.2    Ruuth, E.3    Westwood, R.4    Carnaud, C.5
  • 10
    • 0037300827 scopus 로고    scopus 로고
    • IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice
    • Cardozo AK, Proost P, Gysemans C, Chen MC, Mathieu C, Eizirik DL (2003) IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice. Diabetologia 46: 255-266
    • (2003) Diabetologia , vol.46 , pp. 255-266
    • Cardozo, A.K.1    Proost, P.2    Gysemans, C.3    Chen, M.C.4    Mathieu, C.5    Eizirik, D.L.6
  • 11
    • 0035079807 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells
    • Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL (2001) Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells. Diabetologia 44: 325-332
    • (2001) Diabetologia , vol.44 , pp. 325-332
    • Chen, M.C.1    Proost, P.2    Gysemans, C.3    Mathieu, C.4    Eizirik, D.L.5
  • 15
    • 0032055842 scopus 로고    scopus 로고
    • Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse
    • Dahlen E, Dawe K, Ohlsson L, Hedlund G (1998) Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse. J Immunol 160: 3585-3593
    • (1998) J Immunol , vol.160 , pp. 3585-3593
    • Dahlen, E.1    Dawe, K.2    Ohlsson, L.3    Hedlund, G.4
  • 16
    • 0034596945 scopus 로고    scopus 로고
    • LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells
    • De Y, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J, Oppenheim JJ, Chertov O (2000) LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp Med 192: 1069-1074
    • (2000) J Exp Med , vol.192 , pp. 1069-1074
    • De, Y.1    Chen, Q.2    Schmidt, A.P.3    Anderson, G.M.4    Wang, J.M.5    Wooters, J.6    Oppenheim, J.J.7    Chertov, O.8
  • 17
    • 33644756809 scopus 로고    scopus 로고
    • Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes
    • Devaraj S, Glaser N, Griffen S, Wang-Polagruto J, Miguelino E, Jialal I (2006) Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes. Diabetes 55: 774-779
    • (2006) Diabetes , vol.55 , pp. 774-779
    • Devaraj, S.1    Glaser, N.2    Griffen, S.3    Wang-Polagruto, J.4    Miguelino, E.5    Jialal, I.6
  • 18
    • 84872053925 scopus 로고    scopus 로고
    • Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
    • Diana J, Simoni Y, Furio L, Beaudoin L, Agerberth B, Barrat F, Lehuen A (2013) Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes. Nat Med 19: 65-73
    • (2013) Nat Med , vol.19 , pp. 65-73
    • Diana, J.1    Simoni, Y.2    Furio, L.3    Beaudoin, L.4    Agerberth, B.5    Barrat, F.6    Lehuen, A.7
  • 19
    • 66549108083 scopus 로고    scopus 로고
    • CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions
    • Eash KJ, Means JM, White DW, Link DC (2009) CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions. Blood 113: 4711-4719
    • (2009) Blood , vol.113 , pp. 4711-4719
    • Eash, K.J.1    Means, J.M.2    White, D.W.3    Link, D.C.4
  • 20
    • 77954974268 scopus 로고    scopus 로고
    • CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow
    • Eash KJ, Greenbaum AM, Gopalan PK, Link DC (2010) CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest 120: 2423-2431
    • (2010) J Clin Invest , vol.120 , pp. 2423-2431
    • Eash, K.J.1    Greenbaum, A.M.2    Gopalan, P.K.3    Link, D.C.4
  • 22
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
    • Eizirik DL, Colli ML, Ortis F (2009) The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 5: 219-226
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 24
    • 58149456481 scopus 로고    scopus 로고
    • IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
    • Jacobsen ML, Ronn SG, Bruun C, Larsen CM, Eizirik DL, Mandrup-Poulsen T, Billestrup N (2009) IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells. Diabetologia 52: 281-288
    • (2009) Diabetologia , vol.52 , pp. 281-288
    • Jacobsen, M.L.1    Ronn, S.G.2    Bruun, C.3    Larsen, C.M.4    Eizirik, D.L.5    Mandrup-Poulsen, T.6    Billestrup, N.7
  • 25
    • 0033853921 scopus 로고    scopus 로고
    • Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy
    • Kassem SA, Ariel I, Thornton PS, Scheimberg I, Glaser B (2000) Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy. Diabetes 49: 1325-1333
    • (2000) Diabetes , vol.49 , pp. 1325-1333
    • Kassem, S.A.1    Ariel, I.2    Thornton, P.S.3    Scheimberg, I.4    Glaser, B.5
  • 26
    • 77149144182 scopus 로고    scopus 로고
    • Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10
    • Kelly-Scumpia KM, Scumpia PO, Delano MJ, Weinstein JS, Cuenca AG, Wynn JL, Moldawer LL (2010) Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10. J Exp Med 207: 319-326
    • (2010) J Exp Med , vol.207 , pp. 319-326
    • Kelly-Scumpia, K.M.1    Scumpia, P.O.2    Delano, M.J.3    Weinstein, J.S.4    Cuenca, A.G.5    Wynn, J.L.6    Moldawer, L.L.7
  • 27
    • 33645859604 scopus 로고    scopus 로고
    • A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis
    • Kim ND, Chou RC, Seung E, Tager AM, Luster AD (2006) A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis. J Exp Med 203: 829-835
    • (2006) J Exp Med , vol.203 , pp. 829-835
    • Kim, N.D.1    Chou, R.C.2    Seung, E.3    Tager, A.M.4    Luster, A.D.5
  • 28
    • 84875442814 scopus 로고    scopus 로고
    • Neutrophil recruitment and function in health and inflammation
    • Kolaczkowska E, Kubes P (2013) Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol 13: 159-175
    • (2013) Nat Rev Immunol , vol.13 , pp. 159-175
    • Kolaczkowska, E.1    Kubes, P.2
  • 30
    • 0035856952 scopus 로고    scopus 로고
    • beta-Cell death during progression to diabetes
    • Mathis D, Vence L, Benoist C (2001) beta-Cell death during progression to diabetes. Nature 414: 792-798
    • (2001) Nature , vol.414 , pp. 792-798
    • Mathis, D.1    Vence, L.2    Benoist, C.3
  • 31
    • 84880676381 scopus 로고    scopus 로고
    • Diverse novel functions of neutrophils in immunity, inflammation, and beyond
    • Mocsai A (2013) Diverse novel functions of neutrophils in immunity, inflammation, and beyond. J Exp Med 210: 1283-1299
    • (2013) J Exp Med , vol.210 , pp. 1283-1299
    • Mocsai, A.1
  • 33
    • 77449145225 scopus 로고    scopus 로고
    • Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells
    • Ortis F, Naamane N, Flamez D, Ladriere L, Moore F, Cunha DA, Colli ML, Thykjaer T, Thorsen K, Orntoft TF et al (2010) Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells. Diabetes 59: 358-374
    • (2010) Diabetes , vol.59 , pp. 358-374
    • Ortis, F.1    Naamane, N.2    Flamez, D.3    Ladriere, L.4    Moore, F.5    Cunha, D.A.6    Colli, M.L.7    Thykjaer, T.8    Thorsen, K.9    Orntoft, T.F.10
  • 35
    • 80053321927 scopus 로고    scopus 로고
    • Neutrophils cascading their way to inflammation
    • Sadik CD, Kim ND, Luster AD (2011) Neutrophils cascading their way to inflammation. Trends Immunol 32: 452-460
    • (2011) Trends Immunol , vol.32 , pp. 452-460
    • Sadik, C.D.1    Kim, N.D.2    Luster, A.D.3
  • 36
    • 84869228804 scopus 로고    scopus 로고
    • Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcgammaR signaling
    • Sadik CD, Kim ND, Iwakura Y, Luster AD (2012) Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcgammaR signaling. Proc Natl Acad Sci U S A 109: E3177-E3185
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Sadik, C.D.1    Kim, N.D.2    Iwakura, Y.3    Luster, A.D.4
  • 37
    • 84856059736 scopus 로고    scopus 로고
    • Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking
    • Sanz MJ, Kubes P (2012) Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking. Eur J Immunol 42: 278-283
    • (2012) Eur J Immunol , vol.42 , pp. 278-283
    • Sanz, M.J.1    Kubes, P.2
  • 39
    • 79955476625 scopus 로고    scopus 로고
    • Overcoming hurdles in developing successful drugs targeting chemokine receptors
    • Schall TJ, Proudfoot AE (2011) Overcoming hurdles in developing successful drugs targeting chemokine receptors. Nat Rev Immunol 11: 355-363
    • (2011) Nat Rev Immunol , vol.11 , pp. 355-363
    • Schall, T.J.1    Proudfoot, A.E.2
  • 41
    • 77649312007 scopus 로고    scopus 로고
    • CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse
    • Solomon M, Balasa B, Sarvetnick N (2010) CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse. Autoimmunity 43: 156-163
    • (2010) Autoimmunity , vol.43 , pp. 156-163
    • Solomon, M.1    Balasa, B.2    Sarvetnick, N.3
  • 44
    • 0035717310 scopus 로고    scopus 로고
    • Down-regulation of CXCR1 and CXCR2 expression on human neutrophils upon activation of whole blood by S. aureus is mediated by TNF-alpha
    • Tikhonov I, Doroshenko T, Chaly Y, Smolnikova V, Pauza CD, Voitenok N (2001) Down-regulation of CXCR1 and CXCR2 expression on human neutrophils upon activation of whole blood by S. aureus is mediated by TNF-alpha. Clin Exp Immunol 125: 414-422
    • (2001) Clin Exp Immunol , vol.125 , pp. 414-422
    • Tikhonov, I.1    Doroshenko, T.2    Chaly, Y.3    Smolnikova, V.4    Pauza, C.D.5    Voitenok, N.6
  • 46
    • 0345448056 scopus 로고    scopus 로고
    • Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model
    • Turley S, Poirot L, Hattori M, Benoist C, Mathis D (2003) Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J Exp Med 198: 1527-1537
    • (2003) J Exp Med , vol.198 , pp. 1527-1537
    • Turley, S.1    Poirot, L.2    Hattori, M.3    Benoist, C.4    Mathis, D.5
  • 48
    • 0028111256 scopus 로고
    • Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications
    • Van Rooijen N, Sanders A (1994) Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 174: 83-93
    • (1994) J Immunol Methods , vol.174 , pp. 83-93
    • Van Rooijen, N.1    Sanders, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.