Novel cartilage oligomeric matrix protein (COMP) neoepitopes identified in synovial fluids from patients with joint diseases using affinity chromatography and mass spectrometry

Journal of Biological Chemistry

Volumn 289, Issue 30, 2014, Pages 20908-20916

  Åhrman, Emma ^a   Lorenzo, Pilar ^a   Holmgren, Kristin ^a   Grodzinsky, Alan J ^b   Dahlberg, Leif E ^c   Saxne, Tore ^a   Heinegård, Dick ^a   Önnerfjord, Patrik ^a  

^a LUND UNIVERSITY   (Sweden)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; BODY FLUIDS; CARTILAGE; DISEASE CONTROL; DISEASES; MASS SPECTROMETRY; OLIGOMERS; PROTEINS;

CARTILAGE DESTRUCTION; CARTILAGE MARKERS; DISEASE PROGRESSION; EVALUATION METHODS; ISOLATION AND CHARACTERIZATION; MASS SPECTROMETRIC IDENTIFICATION; PATHOLOGICAL CONDITIONS; RHEUMATOID ARTHRITIS;

JOINTS (ANATOMY);

CARTILAGE OLIGOMERIC MATRIX PROTEIN; EPITOPE; IL6 PROTEIN, HUMAN; IL6R PROTEIN, HUMAN; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AFFINITY CHROMATOGRAPHY; ARTHROPATHY; CELL CULTURE; CHEMISTRY; CLINICAL TRIAL; HUMAN; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; PATHOLOGY; SYNOVIAL FLUID;

ADULT; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CELLS, CULTURED; CHROMATOGRAPHY, AFFINITY; EPITOPES; HUMANS; INTERLEUKIN-6; JOINT DISEASES; MASS SPECTROMETRY; RECEPTORS, INTERLEUKIN-6; SYNOVIAL FLUID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84905372439     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.554683     Document Type: Article

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