Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism

Experimental Dermatology

Volumn 23, Issue 8, 2014, Pages 573-578

  Mantel, Alon ^a   Carpenter Mendini, Amanda ^a   Vanbuskirk, Joanne ^a   Pentland, Alice P ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Aldo keto reductase; PPAR ; Prostaglandin; Skin cancer; Squamous cell carcinoma

Indexed keywords

11 EPIPROSTAGLANDIN F2 ALPHA; ALDO KETO REDUCTASE 1C3; DELTA15 PROSTAGLANDIN J2; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PROSTAGLANDIN D2; PROSTAGLANDIN J2; UNCLASSIFIED DRUG; 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; 15-DEOXYPROSTAGLANDIN J2; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AKR1C3 PROTEIN, HUMAN; PROSTAGLANDIN; SMALL INTERFERING RNA;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; NON MELANOMA SKIN CANCER; PROSTAGLANDIN METABOLISM; PROTEIN EXPRESSION; SKIN CARCINOMA; STABLE EXPRESSION; UPREGULATION; ANALOGS AND DERIVATIVES; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SKIN; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

3-HYDROXYSTEROID DEHYDROGENASES; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; PPAR GAMMA; PROSTAGLANDIN D2; PROSTAGLANDINS; RNA, SMALL INTERFERING; SKIN; SKIN NEOPLASMS; UP-REGULATION;

EID: 84905368052     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/exd.12468     Document Type: Article

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