Bioconversion of deoxysugar moieties to the biosynthetic intermediates of daunorubicin in an engineered strain of Streptomyces coeruleobidus

Biotechnology Letters

Volumn 36, Issue 9, 2014, Pages 1809-1818

  Yuan, Tianjie ^a   Xie, Liping ^a   Zhu, Baoquan ^a   Hu, Youjia ^a  

^a SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY   (China)

Author keywords

Anthracyclines; Biosynthetic gene cluster; Combinatorial biosynthesis; Daunorubicin; Polyketide synthases

Indexed keywords

BACTERIA; BIOACTIVITY; BIOTECHNOLOGY; CLONING; KETONES; STRAIN; SUGARS;

ANTHRACYCLINES; BIOSYNTHETIC GENE CLUSTER; COMBINATORIAL BIOSYNTHESIS; DAUNORUBICIN; POLYKETIDE SYNTHASES;

BIOSYNTHESIS;

STREPTOMYCES;

CARBOHYDRATE; DAUNORUBICIN; DEOXYSUGAR;

BIOSYNTHESIS; BIOTRANSFORMATION; CHEMISTRY; CYTOSOL; GENETICS; METABOLIC ENGINEERING; METABOLISM; MULTIGENE FAMILY; STREPTOMYCES;

BIOSYNTHETIC PATHWAYS; BIOTRANSFORMATION; CARBOHYDRATES; CYTOSOL; DAUNORUBICIN; DEOXY SUGARS; METABOLIC ENGINEERING; MULTIGENE FAMILY; STREPTOMYCES;

EID: 84905239896     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-014-1542-1     Document Type: Article

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