Expression of insulin-like growth factor receptor type 1 correlates with lymphatic metastases in human gastric cancer

Polish Journal of Pathology

Volumn 65, Issue 2, 2014, Pages 135-140

  Gryko, Mariusz ^a   Kiśluk, Joanna ^a   Cepowicz, Dariusz ^a   Zińczuk, Justyna ^a   Kamocki, Zbigniew ^a   Guzińska Ustymowicz, Katarzyna ^a   Pryczynicz, Anna ^a   Czyzewska, Jolanta ^a   Kemona, Andrzej ^a   Kȩdra, Bogusław ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Cancer metastases; Gastric cancer; Gastric cancer metastasis; IGF 1R; Insulin like growth factor receptor 1

Indexed keywords

SOMATOMEDIN C RECEPTOR; TUMOR MARKER;

AGED; ARTICLE; BIOPSY; CANCER GRADING; CARCINOMA; CHEMISTRY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; METASTASIS; MIDDLE AGED; MORTALITY; PATHOLOGY; STOMACH TUMOR; SURVIVAL;

AGED; BIOPSY; CARCINOMA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM GRADING; RECEPTOR, IGF TYPE 1; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84905184696     PISSN: 12339687     EISSN: None     Source Type: Journal    
DOI: 10.5114/pjp.2014.42678     Document Type: Article

References (25)

1. Jemal A, Bray F, Melissa M, et al. Global Cancer Statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Tseng CW, Lin CC, Chen CN, et al. Integrative network analysis reveals active microRNAs and their functions in gastric cancer. BMC Systems Biology 2011; 5: 99.
3. Sepp-Lorenzino L. Structure and function of the insulin-like growth factor I receptor. Breast Cancer Res Treat 1998; 47: 235-253.
4. LeRoith D, Werner H, Beitner-Johnson D, Roberts CT Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev 1995; 16: 143-163.
5. Hernandez-Sanchez C, Werner H, Roberts CT Jr, et al. Differential regulation of insulin-like growth factor-I (IGF-I) receptor gene expression by IGF-I and basic fibroblastic growth factor. J Biol Chem 1997; 272: 4663-4670.
6. Yu H, Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 2000; 92: 1472-1489.
7. LeRoith D, Baserga R, Helman L, Roberts CT Jr. Insulin-like growth factors and cancer. Ann Intern Med 1995; 122: 54-59.
8. Foulstone E, Prince S, Zaccheo O, et al. Insulin-like growth factor ligands, receptors, and binding proteins in cancer. J Pathol 2005; 205: 145-153.
9. Pavelić K, Kolak T, Kapitanović S, et al. Gastric cancer: the role of insulin-like growth factor 2 (IGF 2) and its receptors (IGF 1R and M6-P/IGF 2R). J Pathol 2003; 201: 430-438.
10. Baserga R. The IGF-I receptor in cancer research. Exp Cell Res 1999; 253: 1-6.
11. Ma W, Li W, Fan QX, et al. Expression of IGF-1R in esophageal squamous cell carcinoma and the effect of its silencing by siRNA on the proliferation of esophageal cancer EC9706 cells in vitro. Zhonghua Zhong Liu Za Zhi 2011; 33: 609-612.
12. Pandini G, Vigneri R, Costantino A, et al. Insulin and insulin- like growth factor-I (IGF-I) receptor verexpression in breast cancers leads to insulin/IGF-I hybrid receptor over expression: evidence for a second mechanism of IGF-I signaling. Clin Cancer Res 1999; 5: 1935-1944.
13. Hakam A, Yeatman TJ, Lu L, et al. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Hum Pathol 1999; 30: 1128-1133.
14. Huang F, Xu LA, Khambata-Ford S. Correlation between gene expression of IGF-1R pathway markers and cetuximab benefit in metastatic colorectal cancer. Clin Cancer Res 2012; 18: 1156-1166.
15. Kim YH, Sumiyoshi S, Hashimoto S, et al. Expressions of insulin- like growth factor receptor-1 and insulin-like growth factor binding protein 3 in advanced non-small-cell lung cancer. Clin Lung Cancer 2012; 13: 385-390.
16. Pollak M. The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology. Clin Cancer Res 2012; 18: 40-50.
17. Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. Acta Pathol Microbiol Scand 1965; 64: 31-49.
18. Goseki N, Takizawa T, Koike M. Differences in the mode of extension of gastric cancer classified by histological type: new histological classification of gastric carcinoma. Gut 1992; 33: 606-612.
19. Kubo M, Sasako M, Gotoda T, et al. Endoscopic evaluation of the remnant stomach after gastrectomy: proposal for a new classification. Gastric Cancer 2002; 5: 83-89.
20. Vincent AM, Feldman EL. Control of cell survival by IGF signaling pathways. Growth Horm IGF Res 2002; 12: 193-197.
21. Baserga R. The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res 1995; 55: 249-252.
22. Li H, Adachi Y, Yamamoto H, et al. Insulin-like growth factor- I receptor blockade reduces tumor angiogenesis and enhances the effects of bevacizumab for a human gastric cancer cell line MKN 45. Cancer 2011; 117: 3135-3147.
23. Ge J, Chen Z, Wu S, et al. Expression levels of insulin-like growth factor-1 and multidrug resistance-associated protein-1 indicate poor prognosis in patients with gastric cancer. Digestion 2009; 80: 148-158.
24. Jiang Y, Wang L, Gong W, et al. A high expression level of insulin- like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer. Clin Exp Metastasis 2004; 21: 755-764.
25. Matsubara J, Yamada Y, Hirashima Y, et al. Impact of insulin- like growth factor type 1 receptor, epidermal growth factor receptor, and HER2 expressions on outcomes of patients with gastric cancer. Clin Cancer Res 2008; 14: 3022-3029.