Modeling CVD in human pluripotent cells by genome editing

Journal of the American College of Cardiology

Volumn 64, Issue 5, 2014, Pages 460-462

  Hajjar, Roger J ^a   Hulot, Jean Sebastien ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

cardiomyopathies; disease modeling; genetics; genome editing; stem cells

Indexed keywords

NIFEDIPINE; NUCLEASE; PINACIDIL; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNQ1; RNA; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

CARDIOVASCULAR DISEASE; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CELL CULTURE; CELL DIFFERENTIATION; CHANNEL GATING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONGESTIVE CARDIOMYOPATHY; DISEASE MODEL; DRUG RESEARCH; EMBRYONIC STEM CELL; FIBROBLAST; GENE; GENE INSERTION; GENE MUTATION; GENETIC ENGINEERING; HEART MUSCLE CELL; HEART RIGHT VENTRICLE DYSPLASIA; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; KCNH2 GENE; KCNQ1 GENE; LEOPARD SYNDROME; LONG QT SYNDROME; LONG QT SYNDROME 1; LONG QT SYNDROME 2; NOTE; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RNA EDITING; STEM CELL;

CARDIOMYOPATHIES; DISEASE MODELING; GENETICS; GENOME EDITING; STEM CELLS;

ANTI-ARRHYTHMIA AGENTS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LONG QT SYNDROME;

EID: 84905161777     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.06.005     Document Type: Editorial

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