Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood-brain barrier integrity in experimental cerebral ischemia-reperfusion injury

Journal of Ethnopharmacology

Volumn 155, Issue 1, 2014, Pages 692-701

  Fu, Shuping ^a   Gu, Yong ^a   Jiang, Jian Qin ^c   Chen, Xi ^a   Xu, Mingjing ^a   Chen, Xingmiao ^a   Shen, Jiangang ^a,b  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Calyscosin 7 O d glucoside; Caveolin 1; Cerebral ischemia reperfusion injury; Matrix metalloproteinases; Nitric oxide

Indexed keywords

CALYCOSIN 7 O BETA DEXTRO GLUCOSIDE; CAVEOLIN 1; CLAUDIN 5; GELATINASE A; GELATINASE B; GLUCOSE; GLUCOSIDE; MATRIX METALLOPROTEINASE; NEUROPROTECTIVE AGENT; NITRIC OXIDE; NITRIC OXIDE DONOR; OXYGEN; PROTEIN ZO1; TIGHT JUNCTION PROTEIN; UNCLASSIFIED DRUG; CALYCOSIN-7-O-BETA-D-GLUCOSIDE; ISOFLAVONE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASTRAGALUS PLANT; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; DISEASE MODEL; ISOLATION AND PURIFICATION; METABOLISM; MICROVASCULATURE; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TIME;

RATTUS;

ANIMALS; ASTRAGALUS PLANT; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CAVEOLIN 1; DISEASE MODELS, ANIMAL; GLUCOSIDES; ISOFLAVONES; MALE; MATRIX METALLOPROTEINASES; MICROVESSELS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TIGHT JUNCTION PROTEINS; TIME FACTORS;

EID: 84905114597     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.06.015     Document Type: Article

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