Predictors of response to intramyocardial bone marrow cell treatment in patients with refractory angina and chronic myocardial ischemia

International Journal of Cardiology

Volumn 175, Issue 3, 2014, Pages 539-544

  Rodrigo, Sander F ^a   Van Ramshorst, Jan ^a   Mann, Imke ^a   Leong, Darryl P ^a   Cannegieter, Suzanne C ^a   Al Younis, Imad ^a   Dibbets Schneider, Petra ^a   De Roos, Albert ^a   Fibbe, Willem E ^a   Zwaginga, Jaap Jan ^a,b   Bax, Jeroen J ^a   Schalij, Martin J ^a   Beeres, Saskia L ^a   Atsma, Douwe E ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Jon J Van Rood Center for Clinical Transfusion Medicine Research   (Netherlands)

Author keywords

Bone marrow cell; Cell therapy; Chronic ischemia; Intramyocardial injection

Indexed keywords

ADULT; ANGINA PECTORIS; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CELL THERAPY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE CLASSIFICATION; EXERCISE TEST; FEMALE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HUMAN; INTRAMYOCARDIAL BONE MARROW CELL INJECTION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PATIENT SAFETY; PREDICTION; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT RESPONSE; AGED; BONE MARROW TRANSPLANTATION; COHORT ANALYSIS; DOUBLE BLIND PROCEDURE; FOLLOW UP; HEART MUSCLE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PATHOLOGY; PREDICTIVE VALUE; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

AGED; ANGINA PECTORIS; BONE MARROW TRANSPLANTATION; COHORT STUDIES; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PREDICTIVE VALUE OF TESTS; TREATMENT OUTCOME;

EID: 84905084591     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.06.039     Document Type: Article

References (20)

1. J. Van Ramshorst, J.J. Bax, and S.L. Beeres et al. Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial JAMA 301 19 2009 1997 2004
2. D.W. Losordo, T.D. Henry, and C. Davidson et al. Intramyocardial, autologous CD34 + cell therapy for refractory angina Circ Res 109 4 2011 428 436
3. V. Jeevanantham, M. Butler, A. Saad, A. Abdel-Latif, E.K. Zuba-Surma, and B. Dawn Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis Circulation 126 5 2012 551 568
4. H.F. Tse, S. Thambar, and Y.L. Kwong et al. Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for treatment of severe coronary artery diseases (PROTECT-CAD trial) Eur Heart J 28 24 2007 2998 3005
5. T.S. Li, M. Kubo, K. Ueda, M. Murakami, A. Mikamo, and K. Hamano Impaired angiogenic potency of bone marrow cells from patients with advanced age, anemia, and renal failure J Thorac Cardiovasc Surg 139 2 2010 459 465
6. S. Dimmeler, and A. Leri Aging and disease as modifiers of efficacy of cell therapy Circ Res 102 11 2008 1319 1330
7. M. Vasa, S. Fichtlscherer, and K. Adler et al. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease Circulation 103 24 2001 2885 2890
8. S.L. Beeres, J.J. Bax, and T.A. Kaandorp et al. Usefulness of intramyocardial injection of autologous bone marrow-derived mononuclear cells in patients with severe angina pectoris and stress-induced myocardial ischemia Am J Cardiol 97 9 2006 1326 1331
9. S.F. Rodrigo, J. Van Ramshorst, and S.L. Beeres et al. Intramyocardial injection of bone marrow mononuclear cells in chronic myocardial ischemia patients after previous placebo injection improves myocardial perfusion and anginal symptoms: an intra-patient comparison Am Heart J 164 5 2012 771 778
10. M.D. Cerqueira, N.J. Weissman, and V. Dilsizian et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association Circulation 105 4 2002 539 542
11. R.J. Van der Geest, V.G. Buller, and E. Jansen et al. Comparison between manual and semiautomated analysis of left ventricular volume parameters from short-axis MR images J Comput Assist Tomogr 21 5 1997 756 765
12. Y. Bai, T. Sun, and P. Ye Age, gender and diabetic status are associated with effects of bone marrow cell therapy on recovery of left ventricular function after acute myocardial infarction: a systematic review and meta-analysis Ageing Res Rev 9 4 2010 418 423
13. G.P. Meyer, K.C. Wollert, and J. Lotz et al. Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial Eur Heart J 30 24 2009 2978 2984
14. J.A. Miettinen, K. Ylitalo, and P. Hedberg et al. Determinants of functional recovery after myocardial infarction of patients treated with bone marrow-derived stem cells after thrombolytic therapy Heart 96 5 2010 362 367
15. E.C. Perin, J.T. Willerson, and C.J. Pepine et al. Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial JAMA 307 16 2012 1717 1726
16. F. Cao, D. Sun, and C. Li et al. Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up Eur Heart J 30 16 2009 1986 1994
17. S.A. Sorrentino, F.H. Bahlmann, and C. Besler et al. Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone Circulation 116 2 2007 163 173
18. K.A. Gallagher, Z.J. Liu, and M. Xiao et al. Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha J Clin Invest 117 5 2007 1249 1259
19. M. Vasa, S. Fichtlscherer, and A. Aicher et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease Circ Res 89 1 2001 E1 E7
20. D.J. Ceradini, A.R. Kulkarni, and M.J. Callaghan et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1 Nat Med 10 8 2004 858 864