Usefulness of Intramyocardial Injection of Autologous Bone Marrow-Derived Mononuclear Cells in Patients With Severe Angina Pectoris and Stress-Induced Myocardial Ischemia

American Journal of Cardiology

Volumn 97, Issue 9, 2006, Pages 1326-1331

  Beeres, Saskia L M A ^a   Bax, Jeroen J ^a   Kaandorp, Theodorus A M ^a   Zeppenfeld, Katja ^a   Lamb, Hildo J ^a   Dibbets Schneider, Petra ^a   Stokkel, Marcel P M ^a   Fibbe, Willem E ^a   de Roos, Albert ^a   van der Wall, Ernst E ^a   Schalij, Martin J ^a   Atsma, Douwe E ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANGINA PECTORIS; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CLINICAL ARTICLE; EXERCISE; EXERCISE TEST; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART STRESS; HUMAN; MALE; MONONUCLEAR CELL; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUALITY OF LIFE; SAFETY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYSTOLE; AUTOTRANSPLANTATION; BONE MARROW TRANSPLANTATION; CORONARY ARTERY BLOOD FLOW; EVALUATION; EXERCISE TOLERANCE; FOLLOW UP; HEART; HEART STROKE VOLUME; HEART VENTRICLE; INTRAMUSCULAR DRUG ADMINISTRATION; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; SCINTISCANNING; TRANSPLANTATION; TREATMENT OUTCOME;

ANGINA PECTORIS; BONE MARROW TRANSPLANTATION; CORONARY CIRCULATION; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; FOLLOW-UP STUDIES; HEART; HEART VENTRICLES; HUMANS; INJECTIONS, INTRAMUSCULAR; LEUKOCYTES, MONONUCLEAR; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; QUALITY OF LIFE; STROKE VOLUME; SYSTOLE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

EID: 33744745275     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2005.11.068     Document Type: Article

References (16)

1. Wollert K.C., Meyer G.P., Lotz J., Ringes-Lichtenberg S., Lippolt P., Breidenbach C., Fichtner S., Korte T., Hornig B., Messinger D., et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction. the BOOST randomised controlled clinical trial. Lancet 364 (2004) 141-148
2. Schächinger V., Assmus B., Britten M., Honold J., Lehmann R., Teupe C., Abolmaali N.D., Vogl T., Hofmann W.K., Martin H., Dimmeler S., and Zeiher A.M. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction. final results of the TOPCARE-AMI trial. J Am Coll Cardiol 44 (2004) 1690-1699
3. Chen S.L., Fang W.W., Ye F., Liu Y.H., Qian J., Shan S.J., Zhang J.J., Chunhua R.Z., Liao L.M., Lin S., and Sun J.P. Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol 94 (2004) 92-95
4. Strauer B.E., Brehm M., Zeus T., Kostering, Hernandez A., Sorg R.V., Kögler G., and Wernet P. Repair of infracted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 106 (2002) 1913-1918
5. Fuchs S., Satler L.F., Kornowski R., Okubagzi P., Weisz G., Baffour R., Waksman R., Weissman N.J., Cerqueira M., Leon M.B., and Epstein S.E. Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease. J Am Coll Cardiol 41 (2003) 1721-1724
6. Tse H.F., Kwong Y.L., Chan J.K.F., Lo G., Ho C.L., and Lau C.P. Angiogenesis in ischemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet 361 (2003) 47-49
7. Perin E.C., Silva G.V., and Leite R.S. Left ventricular electromechanical mapping as a diagnostic method. In: Abela G.S. (Ed). Myocardial Revascularization. Novel Percutaneous Approaches (2001), Wiley-Liss, New York 183-195
8. Perin E.C., Dohmann H.F.R., Borojevic R., Silva S.A., Sousa A.L.S., Mesquita C.T., Rossi M.I.D., Carvalho A.C., Dutra H.S., Dohmann H.J.F., et al. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation 107 (2003) 2294-2302
9. Kaandorp T.A.M., Bax J.J., Lamb H.J., Viergever E.P., Boersma E., Poldermans D., van der Wall E.E., and de Roos A. Which parameters on magnetic resonance imaging determine Q waves on the electrocardiogram?. Am J Cardiol 95 (2005) 925-929
10. Cerqueira M.D., Weissman N.J., Dilsizian V., Jacobs A.K., Kaul S., Laskey W.K., Pennell D.J., Rumberger J.A., Ryan T., and Verani M.S. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation 105 (2002) 539-542
11. Plein S., Ridgway J.P., Jones T.R., Bloomer T.N., and Sivananthan M.H. Coronary artery disease. assessment with a comprehensive MR imaging protocol-initial results. Radiology 225 (2002) 300-307
12. Wu E., Judd R.M., Vargas J.D., Klocke F.J., Bonow R.O., and Kim R.J. Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. Lancet 357 (2001) 21-28
13. Borger van der Burg A.E., Bax J.J., Boersma E., Pauwels E.K.J., van der Wall E.E., and Schalij M.J. Impact of viability, ischemia, scar tissue and revascularization on outcome after aborted sudden death. Circulation 108 (2003) 1954-1959
14. Fuchs S., Baffour R., Zhou Y.F., Shou M., Pierre A., Tio F.O., Weissman N.J., Leon M.B., Epstein S.E., and Kornowski R. Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia. J Am Coll Cardiol 37 (2001) 1726-1732
15. Silva G.V., Litovsky S., Assad J.A., Sousa A.L., Martin B.J., Vela D., Coulter S.C., Lin J., Ober J., Vaughn W.K., et al. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 111 (2005) 150-156
16. Perin E.C., Dohmann H.F.R., Borojevic R., Silva S.A., Sousa A.L.S., Silva G.V., Mesquita C.T., Belém L., Vaughn W.K., Rangel F.O.D., et al. Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation 110 suppl II (2004) II-213-II-218