Statin use is associated with improved overall survival without affecting patency and limb salvage rates following open or endovascular revascularization

Vascular Medicine (United Kingdom)

Volumn 19, Issue 2, 2014, Pages 86-93

  Dosluoglu, Hasan H ^a   Davari Farid, Sina ^a   Pourafkari, Leili ^a   Harris, Linda M ^a   Nader, Nader D ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

arterial occlusive diseases; leg; lipids; men; statins

Indexed keywords

ACETYLSALICYLIC ACID; ALBUMIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; COUMADINS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; WARFARIN;

AGED; ALBUMIN BLOOD LEVEL; AMPUTATION FREE SURVIVAL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CRITICAL LIMB ISCHEMIA; DISEASE ASSOCIATION; ENDOVASCULAR REVASCULARIZATION; EVENT FREE SURVIVAL; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; GRAFT PATENCY; HEART DISEASE; HUMAN; HYPERLIPIDEMIA; INTERMITTENT CLAUDICATION; KIDNEY FAILURE; LIMB ISCHEMIA; LIMB SALVAGE; MAJOR CLINICAL STUDY; MALE; MORTALITY; OPEN REVASCULARIZATION; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROPENSITY SCORE; RETROSPECTIVE STUDY; REVASCULARIZATION; SURVIVAL RATE; VEIN GRAFT;

EID: 84905060403     PISSN: 1358863X     EISSN: 14770377     Source Type: Journal    
DOI: 10.1177/1358863X14528271     Document Type: Article

References (30)

1. Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation. 2001 ; 103: 926-933 (Pubitemid 32183796)
2. Moreno PR, Fuster V. The year in atherothrombosis. J Am Coll Cardiol. 2004 ; 44: 2099-2110 (Pubitemid 39585197)
3. Sparrow CP, Burton CA, Hernandez M, et al. Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering. Arterioscler Thromb Vasc Biol. 2001 ; 21: 115-121 (Pubitemid 32061935)
4. Fukumoto Y, Libby P, Rabkin E, et al. Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001 ; 103: 993-999 (Pubitemid 32183806)
5. Wolfrum S, Jensen KS, Liao JK. Endothelium-dependent effects of statins. Arterioscler Thromb Vasc Biol. 2003 ; 23: 729-736 (Pubitemid 36566160)
6. Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA. 1998 ; 279: 1615-1622 (Pubitemid 28248586)
7. White HD, Simes RJ, Anderson NE, et al. Pravastatin therapy and the risk of stroke. N Engl J Med. 2000 ; 343: 317-326 (Pubitemid 30616697)
8. Mohler ER, Hiatt WR, Creager MA. Cholesterol reduction with atorvastatin improves walking distance in patients with peripheral arterial disease. Circulation. 2003 ; 108: 1481-1486 (Pubitemid 37176455)
9. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet. 2002 ; 360: 7-22
10. Randomized trial of the effects of cholesterol-lowering with simvastatin on peripheral vascular and other major vascular outcomes in 20,536 people with peripheral arterial disease and other high-risk conditions. J Vasc Surg. 2007 ; 45: 645-654
11. Abbruzzese TA, Havens J, Belkin M, et al. Statin therapy is associated with improved patency of autogenous infrainguinal bypass grafts. J Vasc Surg. 2004 ; 39: 1178-1185 (Pubitemid 38952583)
12. Henke PK, Blackburn S, Proctor MC, et al. Patients undergoing infrainguinal bypass to treat atherosclerotic vascular disease are underprescribed cardioprotective medications: effect on graft patency, limb salvage, and mortality. J Vasc Surg. 2004 ; 39: 357-365 (Pubitemid 38174318)
13. Schanzer A, Hevelone N, Owens CD, Beckman JA, Belkin M, Conte MS. Statins are independently associated with reduced mortality in patients undergoing infrainguinal bypass graft surgery for critical limb ischemia. J Vasc Surg. 2008 ; 47: 774-781
14. Aiello FA, Khan AA, Meltzer AJ, Gallagher KA, McKinsey JF, Schneider DB. Statin therapy is associated with superior clinical outcomes after endovascular treatment of critical limb ischemia. J Vasc Surg. 2012 ; 55: 371-379
15. Westin GG, Armstrong EJ, Bang H, et al. Association between statin medications and mortality, major adverse cardiovascular event, and amputation-free survival rates in patients with critical limb ischemia. J Am Coll Cardiol. 2014 ; 63: 682-690
16. Durazzo AE, Machado FS, Ikeoka DT, et al. Reduction in cardiovascular events after vascular surgery with atorvastatin: a randomized trial. J Vasc Surg. 2004 ; 39: 967-975
17. O'Neil-Callahan K, Katsimaglis G, Tepper MR, et al. Statins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery: the Statins for Risk Reduction in Surgery (StaRRS) study. J Am Coll Cardiol. 2005 ; 45: 336-342 (Pubitemid 40186781)
18. Poldermans D, Bax JJ, Kertai MD, et al. Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery. Circulation. 2003 ; 107: 1848-1851 (Pubitemid 36444123)
19. Feringa HH, Karagiannis SE, van Waning VH, et al. The effect of intensified lipid-lowering therapy on long-term prognosis in patients with peripheral arterial disease. J Vasc Surg. 2007 ; 45: 936-943 (Pubitemid 46661787)
20. Samson RH. The role of statin drugs in the management of the peripheral vascular patient. Vasc Endovascular Surg. 2008 ; 42: 352-366
21. Barrett TW, Mori M, De Boer D. Association of ambulatory use of statins and beta-blockers with long-term mortality after vascular surgery. J Hosp Med. 2007 ; 2: 241-252 (Pubitemid 47377270)
22. Ward RP, Leeper NJ, Kirkpatrick JN, Lang RM, Sorrentino MJ, Williams KA. The effect of preoperative statin therapy on cardiovascular outcomes in patients undergoing infrainguinal vascular surgery. Int J Cardiol. 2005 ; 104: 264-268 (Pubitemid 41379059)
23. Tattersall MC, Johnson HM, Mason PJ. Contemporary and optimal medical management of peripheral arterial disease. Surg Clin North Am. 2013 ; 93: 761-778
24. Paraskevas KI, Athyros VG, Briana DD, Kakafika AI, Karagiannis A, Mikhailidis DP. Statins exert multiple beneficial effects on patients undergoing percutaneous revascularization procedures. Curr Drug Targets. 2007 ; 8: 942-951
25. Suckow BD, Kraiss LW, Schanzer A, et al. Statin therapy after infrainguinal bypass surgery for critical limb ischemia is associated with improved five-year survival. Society for Vascular Surgery Annual Meeting, National Harbor, MD. 2012 ;:
26. Ridker PM, Rifai N, Pfeffer MA, Sacks F, Braunwald E. Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators. Circulation. 1999 ; 100: 230-235 (Pubitemid 29340127)
27. Vogel TR, Dombrovskiy VY, Galinanes EL, Kruse RL. Preoperative statins and limb salvage after lower extremity revascularization in the medicare population. Circ Cardiovasc Interv. 2013 ; 6: 694-700
28. Hirsch AT, Haskal ZJ, Hertzer NR, et al. ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation. 2006 ; 113: e463-654
29. McFalls EO, Ward HB, Moritz TE, et al. Coronary-artery revascularization before elective major vascular surgery. N Engl J Med. 2004 ; 351: 2795-2804 (Pubitemid 40051903)
30. Owens CD, Ridker PM, Belkin M, et al. Elevated C-reactive protein levels are associated with postoperative events in patients undergoing lower extremity vein bypass surgery. J Vasc Surg. 2007 ; 45: 2-9 (Pubitemid 46038651)