Interplay between the intracellular energy sensor AMP-activated protein kinase (AMPK) and the estrogen receptor activities in regulating rat pituitary tumor cell (GH3) growth in vitro

Pituitary

Volumn 17, Issue 3, 2014, Pages 203-209

  Tulipano, Giovanni ^a   Faggi, Lara ^a   Cacciamali, Andrea ^a   Spinello, Maurizio ^b   Cocchi, Daniela ^a   Giustina, Andrea ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Italy   (Italy)

Author keywords

2 Deoxyglucose; AMP activated protein kinase; Estrogen receptor; Fulvestrant; GH prolactin secreting pituitary tumor; GH3 cells

Indexed keywords

5 AMINOIMIDAZOLE 4 CARBOXAMIDE RIBONUCLEOSIDE; ANTINEOPLASTIC AGENT; DEOXYGLUCOSE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PHOSPHOTRANSFERASE; PROTEIN LBK1; UNCLASSIFIED DRUG; ANTIMETABOLITE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ANTAGONIST; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL COUNT; CELL ENERGY; CELL PROLIFERATION; CELL VIABILITY; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HYPOPHYSIS TUMOR; IN VITRO STUDY; MONOTHERAPY; NONHUMAN; PITUITARY TUMOR CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; TUMOR GROWTH; ANALOGS AND DERIVATIVES; ANIMAL; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIMETABOLITES; CELL LINE, TUMOR; DEOXYGLUCOSE; ESTRADIOL; ESTROGEN RECEPTOR ANTAGONISTS; PITUITARY NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTORS, ESTROGEN;

EID: 84905043861     PISSN: 1386341X     EISSN: 15737403     Source Type: Journal    
DOI: 10.1007/s11102-013-0488-y     Document Type: Article

References (19)

1. Newton CJ (1995) Estrogen blockade by the pure antiestrogen ZM 182730 induces death of pituitary tumor cells. J Ster Biochem Mol Biol 55:327-336
2. Kansra S, Chen S, Bangaru MLY, Sneade L, Dunckley JA, Ben-Jonathan N (2010) Selective estrogen receptor down-regulator and selective estrogen receptor modulators differentially regulate lactotroph proliferation. PLoS ONE 5(4):e10060
3. Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG (2003) Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2:28
4. Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D (2003) LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr Biol 13:2004-2008 (Pubitemid 37425212)
5. Hardie DG (2007) AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 8:774-785
6. Towler MC, Hardie GD (2007) AMP-Activated protein kinase in metabolic control and insulin signaling. Circ Res 100:328-341
7. Motoshima H, Goldstein BJ, Igata M, Araki E (2006) AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 574:63-71 (Pubitemid 43905797)
8. Park HU, Suy S, Danner M, Dailey V, Zhang Y, Li H, Hyduke DR, Collins BT, Gagnon G, Kallakury B, Kumar D, Brown ML, Fornace A, Dritschilo A, Collins SP (2009) AMP-activated protein kinase promotes human prostate cancer cell growth and survival. Mol Cancer Ther 8:733-741
9. Brown KA, McInnes KJ, Takagi K, Ono K, Hunger NI, Wang L, Sasano H, Simpson ER (2011) LKB1 expression is inhibited by estradiol 17-beta in MCF-7 cells. J Ster Biochem Mol Biol 127:439-443
10. Tulipano G, Giovannini M, Spinello M, Sibilia V, Giustina A, Cocchi D (2011) AMP-activated protein kinase regulates normal rat somatotroph cell function and growth of rat pituitary adenomatous cells. Pituitary 14:242-252
11. Tulipano G, Faggi L, Losa M, Mortini P, Spinello M, Sibilia V, Pagani F, Cocchi D, Giustina A (2013) Effects of AMPK activation and combined treatment with AMPK activator and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary tumor cells. Mol Cell Endocrinol 365:167-206
12. Miller M, Chen S, Woodliff J, Kansra S (2008) Curcumin (diferuloylmethane) inhibits cell proliferation, induces apoptosis, and decreases hormone levels and secretion in pituitary tumor cells. Endocrinology 149:4158-4167
13. Vega-Avila E, Pugsley MK (2011) An overview of colorimetric assay methods used to assess survival or proliferation of mammalian cells. Proc West Pharmacol Soc 54:10-14
14. Tulipano G, Bonfanti C, Poiesi C, Burattin A, Turazzi S, Barone G, Cozzi R, Bollati A, Valle D, Giustina A (2004) Effects of the selective estrogen receptor modulator LY117018 on growth hormone secretion: in vitro studies. Metabolism 53:563-570 (Pubitemid 38596526)
15. Lim CT, Kola B, Korbonits M (2009) AMPK as a mediator of hormonal signalling. J Mol Endocrinol 44:87-97
16. Tulipano G, Faggi L, Sibilia V, Giustina A (2012) Points of integration between the intracellular energy sensor AMP-activated protein kinase (AMPK) activity and the somatotroph axis function. Endocrine 42:292-298
17. Bénéteau M, Zunino B, Jacquin MA, Meynet O, Chiche J, Pradelli LA, Marchetti S, Cornille A, Carles M, Ricci JE (2012) Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response. Proc Natl Acad Sci USA 109:20071-20076
18. Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang CC, Itani SI, Lodish HF, Ruderman NB (2002) Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 99:16309-16313 (Pubitemid 35462791)
19. Guo D, Cloughesy TF, Radu CG, Mischell PS (2010) AMPK: a metabolic checkpoint that regulates the growth of EGFR activated glioblastomas. Cell Cycle 9:211-212