-
1
-
-
80052485674
-
The microtubule depolymerizing agent naphthazarin induces both apoptosis and autophagy in A549 lung cancer cells
-
Acharya BR, Bhattacharyya S, Choudhury D, Chakrabarti G. 2011. The microtubule depolymerizing agent naphthazarin induces both apoptosis and autophagy in A549 lung cancer cells. Apoptosis 16:924-939.
-
(2011)
Apoptosis
, vol.16
, pp. 924-939
-
-
Acharya, B.R.1
Bhattacharyya, S.2
Choudhury, D.3
Chakrabarti, G.4
-
2
-
-
84877803986
-
Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin
-
Azcárate IG, Marín-García P, Camacho N, Pérez-Benavente S, Puyet A, Diez A, Ribas de Pouplana L, Bautista JM. 2013. Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin. Br. J. Pharmacol. 169:645-658.
-
(2013)
Br. J. Pharmacol.
, vol.169
, pp. 645-658
-
-
Azcárate, I.G.1
Marín-García, P.2
Camacho, N.3
Pérez-Benavente, S.4
Puyet, A.5
Diez, A.6
Ribas de Pouplana, L.7
Bautista, J.M.8
-
3
-
-
0000335680
-
Borrelidin, a new antibiotic with antiborrelia activity and penicillin enhancement properties
-
Berger J, Jampolsky LM, Goldberg MW. 1949. Borrelidin, a new antibiotic with antiborrelia activity and penicillin enhancement properties. Arch. Biochem. 22:476-478.
-
(1949)
Arch. Biochem.
, vol.22
, pp. 476-478
-
-
Berger, J.1
Jampolsky, L.M.2
Goldberg, M.W.3
-
5
-
-
77649317105
-
The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization
-
Brüning A, Rahmeh M, Gingelmaier A, Friese K. 2010. The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization. Mol. Cancer 9:19.
-
(2010)
Mol. Cancer
, vol.9
, pp. 19
-
-
Brüning, A.1
Rahmeh, M.2
Gingelmaier, A.3
Friese, K.4
-
7
-
-
0001637870
-
Permanent cell line expressing human factor VIII-related antigen established by hybridization
-
Edgell CJ, McDonald CC, Graham JB. 1983. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc. Natl. Acad. Sci. U. S. A. 80:3734-3737.
-
(1983)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 3734-3737
-
-
Edgell, C.J.1
McDonald, C.C.2
Graham, J.B.3
-
8
-
-
84867047851
-
Borrelidin, a potent antifungal agent: insight into the antifungal mechanism against Phytophthora sojae
-
Gao YM, Wang XJ, Zhang J, Li M, Liu CX, An J, Jiang L, Xiang WS. 2012. Borrelidin, a potent antifungal agent: insight into the antifungal mechanism against Phytophthora sojae. J. Agric. Food Chem. 60:9874-9881.
-
(2012)
J. Agric. Food Chem.
, vol.60
, pp. 9874-9881
-
-
Gao, Y.M.1
Wang, X.J.2
Zhang, J.3
Li, M.4
Liu, C.X.5
An, J.6
Jiang, L.7
Xiang, W.S.8
-
9
-
-
84866732814
-
Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia
-
Habibi D, Ogloff N, Jalili RB, Yost A, Weng AP, Ghahary A, Ong CJ. 2012. Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia. Invest. New Drugs 30:1361-1370.
-
(2012)
Invest. New Drugs
, vol.30
, pp. 1361-1370
-
-
Habibi, D.1
Ogloff, N.2
Jalili, R.B.3
Yost, A.4
Weng, A.P.5
Ghahary, A.6
Ong, C.J.7
-
10
-
-
79957618355
-
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
-
Ishiyama A, Iwatsuki M, Namatame M, Nishihara-Tsukashima A, Sunazuka T, Takahashi Y, Omura S, Otoguro K. 2011. Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum. J. Antibiot. (Tokyo) 64:381-384.
-
(2011)
J. Antibiot. (Tokyo)
, vol.64
, pp. 381-384
-
-
Ishiyama, A.1
Iwatsuki, M.2
Namatame, M.3
Nishihara-Tsukashima, A.4
Sunazuka, T.5
Takahashi, Y.6
Omura, S.7
Otoguro, K.8
-
11
-
-
0041322728
-
Anti-angiogenesis effects of borrelidin are mediated through distinct pathways: threonyl-tRNA synthetase and caspases are independently involved in suppression of proliferation and induction of apoptosis in endothelial cells
-
Kawamura T, Liu D, Towle MJ, Kageyama R, Tsukahara N, Wakabayashi T, Littlefield BA. 2003. Anti-angiogenesis effects of borrelidin are mediated through distinct pathways: threonyl-tRNA synthetase and caspases are independently involved in suppression of proliferation and induction of apoptosis in endothelial cells. J. Antibiot. (Tokyo) 56:709-715.
-
(2003)
J. Antibiot. (Tokyo)
, vol.56
, pp. 709-715
-
-
Kawamura, T.1
Liu, D.2
Towle, M.J.3
Kageyama, R.4
Tsukahara, N.5
Wakabayashi, T.6
Littlefield, B.A.7
-
12
-
-
84867887068
-
The nucleoside antagonist cordycepin causes DNA double strand breaks in breast cancer cells
-
Lee HJ, Burger P, Vogel M, Friese K, Brüning A. 2012. The nucleoside antagonist cordycepin causes DNA double strand breaks in breast cancer cells. Invest. New Drugs 30:1917-1925.
-
(2012)
Invest. New Drugs
, vol.30
, pp. 1917-1925
-
-
Lee, H.J.1
Burger, P.2
Vogel, M.3
Friese, K.4
Brüning, A.5
-
13
-
-
84879547598
-
Triple-negative breast cancer: new perspectives for novel therapies
-
Mahamodhossen YA, Liu W, Rong-Rong Z. 2013. Triple-negative breast cancer: new perspectives for novel therapies. Med. Oncol. 30:653.
-
(2013)
Med. Oncol.
, vol.30
, pp. 653
-
-
Mahamodhossen, Y.A.1
Liu, W.2
Rong-Rong, Z.3
-
14
-
-
0034816408
-
Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2
-
Martin SS, Leder P. 2001. Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2. Mol. Cell. Biol. 21:6529-6536.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6529-6536
-
-
Martin, S.S.1
Leder, P.2
-
15
-
-
12844272819
-
A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases
-
Ruan B, Bovee ML, Sacher M, Stathopoulos C, Poralla K, Francklyn CS, Söll D. 2005. A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases. J. Biol. Chem. 280:571-577.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 571-577
-
-
Ruan, B.1
Bovee, M.L.2
Sacher, M.3
Stathopoulos, C.4
Poralla, K.5
Francklyn, C.S.6
Söll, D.7
-
16
-
-
65349157894
-
A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with breast cancer
-
Sekine I, Shimizu C, Nishio K, Saijo N, Tamura T. 2009. A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with breast cancer. Int. J. Clin. Oncol. 14:112-119.
-
(2009)
Int. J. Clin. Oncol.
, vol.14
, pp. 112-119
-
-
Sekine, I.1
Shimizu, C.2
Nishio, K.3
Saijo, N.4
Tamura, T.5
-
17
-
-
84875423790
-
Borrelidin analogues with antimalarial activity: design, synthesis and biological evaluation against Plasmodium falciparum parasites
-
Sugawara A, Tanaka T, Hirose T, Ishiyama A, Iwatsuki M, Takahashi Y, Otoguro K, Omura S, Sunazuka T. 2013. Borrelidin analogues with antimalarial activity: design, synthesis and biological evaluation against Plasmodium falciparum parasites. Bioorg. Med. Chem. Lett. 23:2302-2305.
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 2302-2305
-
-
Sugawara, A.1
Tanaka, T.2
Hirose, T.3
Ishiyama, A.4
Iwatsuki, M.5
Takahashi, Y.6
Otoguro, K.7
Omura, S.8
Sunazuka, T.9
-
18
-
-
33644928489
-
BCL2 family of apoptosis-related genes: functions and clinical implications in cancer
-
Thomadaki H, Scorilas A. 2006. BCL2 family of apoptosis-related genes: functions and clinical implications in cancer. Crit. Rev. Clin. Lab. Sci. 43:1-67.
-
(2006)
Crit. Rev. Clin. Lab. Sci.
, vol.43
, pp. 1-67
-
-
Thomadaki, H.1
Scorilas, A.2
-
19
-
-
0030752706
-
Borrelidin is an angiogenesis inhibitor; disruption of angiogenic capillary vessels in a rat aorta matrix culture model
-
Wakabayashi T, Kageyama R, Naruse N, Tsukahara N, Funahashi Y, Kitoh K, Watanabe Y. 1997. Borrelidin is an angiogenesis inhibitor; disruption of angiogenic capillary vessels in a rat aorta matrix culture model. J. Antibiot. (Tokyo) 50:671-676.
-
(1997)
J. Antibiot. (Tokyo)
, vol.50
, pp. 671-676
-
-
Wakabayashi, T.1
Kageyama, R.2
Naruse, N.3
Tsukahara, N.4
Funahashi, Y.5
Kitoh, K.6
Watanabe, Y.7
-
20
-
-
33749235707
-
Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain
-
Wilkinson B, Gregory MA, Moss SJ, Carletti I, Sheridan RM, Kaja A, Ward M, Olano C, Mendez C, Salas JA, Leadlay PF, vanGinckel R, Zhang MQ. 2006. Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain. Bioorg. Med. Chem. Lett. 16:5814-5817.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 5814-5817
-
-
Wilkinson, B.1
Gregory, M.A.2
Moss, S.J.3
Carletti, I.4
Sheridan, R.M.5
Kaja, A.6
Ward, M.7
Olano, C.8
Mendez, C.9
Salas, J.A.10
Leadlay, P.F.11
vanGinckel, R.12
Zhang, M.Q.13
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