Multi-electrode array study of neuronal cultures expressing nicotinic (β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy

Frontiers in Neural Circuits

Volumn 8, Issue JULY, 2014, Pages

  Gullo, Francesca ^a   Manfredi, Irene ^b   Lecchi, Marzia ^a   Casari, Giorgio ^b   Wanke, Enzo ^a   Becchetti, Andrea ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Carbamazepine; MEA; nAChR; 2 V287L

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; CARBAMAZEPINE; NICOTINIC RECEPTOR; PENICILLIN G; ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; LEUCINE; NICOTINIC RECEPTOR BETA2; VALINE;

ANALYTICAL EQUIPMENT; ANIMAL CELL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL DOMINANT NOCTURNAL FRONTAL LOBE EPILEPSY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SCREENING; DRUG TARGETING; EPILEPTIC DISCHARGE; FRONTAL LOBE EPILEPSY; IN VITRO STUDY; MOUSE; MULTIELECTRODE ARRAY; NEOCORTEX; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE CELL STIMULATION; NOCTURNAL SEIZURE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SYNAPTIC TRANSMISSION; WAVEFORM; WILD TYPE; ACTION POTENTIAL; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; DISEASE MODEL; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; MUTATION; NERVE CELL; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; BENZODIAZEPINES; CARBAMAZEPINE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPILEPSY, FRONTAL LOBE; LEUCINE; MICE; MICE, TRANSGENIC; MUTATION; NERVE NET; NEURONS; RECEPTORS, NICOTINIC; TRANSFECTION; VALINE;

EID: 84904978153     PISSN: 16625110     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncir.2014.00087     Document Type: Article

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