-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
2
-
-
0032767387
-
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
-
Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase IIclinical trials. J Clin Oncol. 1999;17:2572-2578. (Pubitemid 29368260)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.8
, pp. 2572-2578
-
-
Wong, E.T.1
Hess, K.R.2
Gleason, M.J.3
Jaeckle, K.A.4
Kyritsis, A.P.5
Prados, M.D.6
Levin, V.A.7
Yung, W.K.A.8
-
3
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol. 2009;27:4733-4740.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
-
4
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followedbybevacizumab plus irinotecanattumor progressioninrecurrent glioblastoma
-
Kreisl TN, Kim L, Moore K, et al. Phase II trial of single-agent bevacizumab followedbybevacizumab plus irinotecanattumor progressioninrecurrent glioblastoma. J Clin Oncol. 2009;27:740-745.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
-
5
-
-
79953840934
-
Areview of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma
-
Reardon DA, Turner S, Peters KB, et al. Areview of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma. J Natl Compr Canc Netw. 2011;9:414-427.
-
(2011)
J Natl Compr Canc Netw.
, vol.9
, pp. 414-427
-
-
Reardon, D.A.1
Turner, S.2
Peters, K.B.3
-
6
-
-
84879044903
-
Phase III trial of bevacizumab added to standard radiotherapy andtemozolomide fornewlydiagnosedglioblastoma: Matureprogression free survival and preliminary overallsurvival results
-
Washington DC.: Neuro-Oncology
-
Chinot O. Phase III trial of bevacizumab added to standard radiotherapy andtemozolomide fornewlydiagnosedglioblastoma: matureprogression free survival and preliminary overallsurvival results. In AVAglio, Society for Neuro-Oncology 17th Annual Scientific Meeting and Education Day. Washington DC.: Neuro-Oncology, 2012.
-
(2012)
AVAglio, Society for Neuro-Oncology 17th Annual Scientific Meeting and Education Day
-
-
Chinot, O.1
-
7
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature. 2011;473:298-307.
-
(2011)
Nature
, vol.473
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
8
-
-
78651408563
-
Glioblastoma recurrence after Cediranib therapyin patients: Lack of "Rebound" revascularizationasmode of escape
-
di Tomaso E, Snuderl M, Kamoun WS, et al. Glioblastoma recurrence after cediranib therapyin patients: lack of "rebound" revascularizationasmode of escape. Cancer Res. 2011;71:19-28.
-
(2011)
Cancer Res.
, vol.71
, pp. 19-28
-
-
Di Tomaso, E.1
Snuderl, M.2
Kamoun, W.S.3
-
9
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010;141:39-51.
-
(2010)
Cell.
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
10
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
Denardo DG, Brennan DJ, Rexhepaj E, et al. Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy. Cancer Discov. 2011;1:54-67.
-
(2011)
Cancer Discov.
, vol.1
, pp. 54-67
-
-
Denardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
-
11
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
DOI 10.1002/path.1027
-
Bingle L, Brown NJ, Lewis CE. Therole of tumour-associated macrophages in tumour progression: implications for newanticancer therapies. J Pathol. 2002;196:254-265. (Pubitemid 34189413)
-
(2002)
Journal of Pathology
, vol.196
, Issue.3
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
12
-
-
0035911221
-
Colony-stimulatingfactor1promotes progression of mammary tumors to malignancy
-
Lin EY, Nguyen AV, Russell RG, et al. Colony-stimulatingfactor1promotes progression of mammary tumors to malignancy. J Exp Med. 2001; 193:727-740.
-
(2001)
J Exp Med.
, vol.193
, pp. 727-740
-
-
Lin, E.Y.1
Nguyen, A.V.2
Russell, R.G.3
-
13
-
-
50249144131
-
Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
-
Komohara Y, Ohnishi K, Kuratsu J, et al. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol. 2008;216:15-24.
-
(2008)
J Pathol.
, vol.216
, pp. 15-24
-
-
Komohara, Y.1
Ohnishi, K.2
Kuratsu, J.3
-
14
-
-
0032926784
-
Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas
-
Nishie A, Ono M, Shono T, et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin Cancer Res. 1999;5:1107-1113. (Pubitemid 29233226)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.5
, pp. 1107-1113
-
-
Nishie, A.1
Ono, M.2
Shono, T.3
Fukushi, J.4
Otsubo, M.5
Onoue, H.6
Ito, Y.7
Inamura, T.8
Ikezaki, K.9
Fukui, M.10
Iwaki, T.11
Kuwano, M.12
-
15
-
-
0024338056
-
The mononuclear cell infiltrate compared with survival in high-grade astrocytomas
-
DOI 10.1007/BF00688208
-
Rossi ML, Jones NR, Candy E, et al. The mononuclear cell infiltrate compared with survival in high-grade astrocytomas. Acta Neuropathol. 1989;78:189-193. (Pubitemid 19160923)
-
(1989)
Acta Neuropathologica
, vol.78
, Issue.2
, pp. 189-193
-
-
Rossi, M.L.1
Jones, N.R.2
Candy, E.3
Nicoll, J.A.R.4
Compton, J.S.5
Hughes, J.T.6
Esiri, M.M.7
Moss, T.H.8
Cruz-Sanchez, F.F.9
Coakham, H.B.10
-
16
-
-
34548760331
-
Increased glioma growth in mice depleted of macrophages
-
DOI 10.1158/0008-5472.CAN-07-0177
-
Galarneau H, Villeneuve J, Gowing G, et al. Increased Glioma Growth in Mice Depleted of Macrophages. Cancer Res. 2007;67:8874-8881. (Pubitemid 47437464)
-
(2007)
Cancer Research
, vol.67
, Issue.18
, pp. 8874-8881
-
-
Galarneau, H.1
Villeneuve, J.2
Gowing, G.3
Julien, J.-P.4
Vallieres, L.5
-
17
-
-
67649448823
-
Tumor-associated macrophage/microglia infiltration in humangliomasis correlated with MCP-3, butnot MCP-1
-
Okada M, Saio M, Kito Y, et al. Tumor-associated macrophage/microglia infiltration in humangliomasis correlated with MCP-3, butnot MCP-1. Int J Oncol. 2009;34:1621-1627.
-
(2009)
Int J Oncol.
, vol.34
, pp. 1621-1627
-
-
Okada, M.1
Saio, M.2
Kito, Y.3
-
18
-
-
34547820876
-
+ myeloid cells
-
DOI 10.1038/nbt1323, PII NBT1323
-
Shojaei F, Wu X, Malik AK, et al. Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat Biotechnol. 2007;25:911-920. (Pubitemid 47236916)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.8
, pp. 911-920
-
-
Shojaei, F.1
Wu, X.2
Malik, A.K.3
Zhong, C.4
Baldwin, M.E.5
Schanz, S.6
Fuh, G.7
Gerber, H.-P.8
Ferrara, N.9
-
19
-
-
79960406166
-
Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept
-
de Groot JF, Piao Y, Tran H, et al. Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept. Clin Cancer Res. 2011;17:4872-4881.
-
(2011)
Clin Cancer Res.
, vol.17
, pp. 4872-4881
-
-
De Groot, J.F.1
Piao, Y.2
Tran, H.3
-
20
-
-
33747490400
-
A lego system for conditional inference
-
DOI 10.1198/000313006X118430
-
Hothorn T, Hornik K, vande Wiel MA, et al. A Lego System for Conditional Inference. The American Statistician. 2006;60:257-263. (Pubitemid 44257518)
-
(2006)
American Statistician
, vol.60
, Issue.3
, pp. 257-263
-
-
Hothorn, T.1
Hornik, K.2
Van De Wiel, M.A.3
Zeileis, A.4
-
21
-
-
83455203338
-
Identification and manipulation of tumor associated macrophages in human cancers
-
Heusinkveld M, van der Burg SH. Identification and manipulation of tumor associated macrophages in human cancers. J Transl Med. 2011;9:216.
-
(2011)
J Transl Med.
, vol.9
, pp. 216
-
-
Heusinkveld, M.1
Van Der Burg, S.H.2
-
22
-
-
30944446883
-
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
-
DOI 10.1038/ncponc0403, PII N0403
-
Jain RK, Duda DG, Clark JW, et al. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol. 2006;3:24-40. (Pubitemid 43108832)
-
(2006)
Nature Clinical Practice Oncology
, vol.3
, Issue.1
, pp. 24-40
-
-
Jain, R.K.1
Duda, D.G.2
Clark, J.W.3
Loeffler, J.S.4
-
23
-
-
70350142397
-
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
-
Iwamoto FM, Abrey LE, Beal K, et al. Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology. 2009;73:1200-1206.
-
(2009)
Neurology
, vol.73
, pp. 1200-1206
-
-
Iwamoto, F.M.1
Abrey, L.E.2
Beal, K.3
-
24
-
-
41649112610
-
Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
-
Norden AD, Young GS, Setayesh K, et al. Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology. 2008;70:779-787.
-
(2008)
Neurology
, vol.70
, pp. 779-787
-
-
Norden, A.D.1
Young, G.S.2
Setayesh, K.3
-
25
-
-
80052674321
-
Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas
-
Shirai K, Siedow MR, Chakravarti A. Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas. J Oncol. 2012;2012:193436.
-
(2012)
J Oncol.
, vol.2012
, pp. 193436
-
-
Shirai, K.1
Siedow, M.R.2
Chakravarti, A.3
-
26
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
-
Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol. 2010;11: 889-896.
-
(2010)
Nat Immunol.
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
27
-
-
78651417422
-
Polarization of tumor-associated macrophages: A novel strategy for vascular normalization and antitumor immunity
-
Huang Y, Snuderl M, Jain RK. Polarization of tumor-associated macrophages: a novel strategy for vascular normalization and antitumor immunity. Cancer Cell. 2011;19:1-2.
-
(2011)
Cancer Cell
, vol.19
, pp. 1-2
-
-
Huang, Y.1
Snuderl, M.2
Jain, R.K.3
-
28
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
DOI 10.1158/0008-5472.CAN-05-4005
-
Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006;66:605-612. (Pubitemid 43165918)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
29
-
-
26044442817
-
Macrophages direct tumour histology and clinical outcome in a colon cancer model
-
DOI 10.1002/path.1830
-
Oosterling SJ, van der Bij GJ, Meijer GA, et al. Macrophages direct tumour histology and clinical outcome in a colon cancer model. J Pathol. 2005;207:147-155. (Pubitemid 41404145)
-
(2005)
Journal of Pathology
, vol.207
, Issue.2
, pp. 147-155
-
-
Oosterling, S.J.1
Van Der Bij, G.J.2
Meijer, G.A.3
Tuk, C.W.4
Van Garderen, E.5
Van Rooijen, N.6
Meijer, S.7
Van Der Sijp, J.R.M.8
Beelen, R.H.J.9
Van Egmond, M.10
-
30
-
-
77952309402
-
Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice
-
de Groot JF, Fuller G, Kumar AJ, et al. Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice. Neuro Oncol. 2010;12:233-242.
-
(2010)
Neuro Oncol.
, vol.12
, pp. 233-242
-
-
De Groot, J.F.1
Fuller, G.2
Kumar, A.J.3
-
31
-
-
84861145421
-
Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy
-
Delay M, Jahangiri A, Carbonell WS, et al. Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy. Clin Cancer Res. 2012;18:2930-2942.
-
(2012)
Clin Cancer Res.
, vol.18
, pp. 2930-2942
-
-
Delay, M.1
Jahangiri, A.2
Carbonell, W.S.3
-
32
-
-
68049093213
-
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy
-
Lucio-Eterovic AK, Piao Y, de Groot JF. Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin Cancer Res. 2009;15:4589-4599.
-
(2009)
Clin Cancer Res.
, vol.15
, pp. 4589-4599
-
-
Lucio-Eterovic, A.K.1
Piao, Y.2
De Groot, J.F.3
-
33
-
-
67651160649
-
CD4(+) tcells regulate pulmonary metastasis of mammary carcinomasbyenhancing protumor properties of macrophages
-
DeNardo DG, Barreto JB, Andreu P, et al. CD4(+) Tcells regulate pulmonary metastasis of mammary carcinomasbyenhancing protumor properties of macrophages. Cancer Cell. 2009;16:91-102.
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
Barreto, J.B.2
Andreu, P.3
-
34
-
-
78651109040
-
C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells
-
Hiratsuka S, Duda DG, Huang Y, et al. C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Proceedings of the National Academy of Sciences. 2011;108:302-307.
-
(2011)
Proceedings of the National Academy of Sciences.
, vol.108
, pp. 302-307
-
-
Hiratsuka, S.1
Duda, D.G.2
Huang, Y.3
-
35
-
-
0035678053
-
Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumors
-
Yao Y, Kubota T, Sato K, et al. Macrophage Infiltration-associated Thymidine Phosphorylase Expression Correlates with Increased Microvessel Density and Poor Prognosis in Astrocytic Tumors. Clinical Cancer Research. 2001;7:4021-4026. (Pubitemid 34044622)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.12
, pp. 4021-4026
-
-
Yao, Y.1
Kubota, T.2
Sato, K.3
Kitai, R.4
-
36
-
-
84865199671
-
Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas
-
Engler JR, Robinson AE, Smirnov I, et al. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS One. 2012;7:e43339.
-
(2012)
PLoS One
, vol.7
-
-
Engler, J.R.1
Robinson, A.E.2
Smirnov, I.3
|