Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection

Journal of Lipid Research

Volumn 55, Issue 8, 2014, Pages 1772-1783

  Damen, Carola W N ^a,b   Isaac, Giorgis ^c   Langridge, James ^c   Hankemeier, Thomas ^a,b   Vreeken, Rob J ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c WATERS CORPORATION   (United States)

Author keywords

Charge surface hybrid column; Ion mobility high resolution mass spectrometry; Structural elucidation; Ultraperformance liquid chromatography

Indexed keywords

1 NONADECANOYL 2 HYDROXY SN GLYCERO 3 PHOSPHOCHOLINE; 1,2 DIHEPTADECANOYL SN GLYCERO 3 PHOSPHOCHOLINE; 1,2 DIPENTADECANOYL SN GLYCERO 3 PHOSPHOETHANOLAMINE; 2 PROPANOL; ACETONITRILE; AMMONIUM FORMATE; CARDIOLIPIN; CHOLESTEROL; CHOLESTEROL ESTER; DIACYLGLYCEROL; FATTY ACID; FORMIC ACID; LIPID; LYSO PHOSPHATIDYLETHANOLAMIDE; LYSO PHOSPHATIDYLGLYCEROL; LYSO PHOSPHATIDYLINOSITOL; LYSO PHOSPHATIDYLSERINE; MONOACYLGLYCEROL; PHOSPHATIDYLSERINE; PHOSPHORYLCHOLINE; SPHINGOLIPID; SPHINGOMYELIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BIOCHEMICAL EQUIPMENT; CHARGE SURFACE HYBRID; CONTROLLED STUDY; EQUIPMENT DESIGN; FLOW RATE; HUMAN; ION MOBILITY SPECTROMETRY; LIPID ANALYSIS; MASS SPECTROMETER; MASS SPECTROMETRY; OPTICAL RESOLUTION; PHYSICAL PHASE; PLASMA; PRIORITY JOURNAL; PROCESS TECHNOLOGY; QUADRUPOLE MASS SPECTROMETRY; REACTION TIME; REVERSED PHASE ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; BLOOD; CHEMISTRY; DEVICES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; PROCEDURES;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LIPIDS; MASS SPECTROMETRY;

EID: 84904962995     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.D047795     Document Type: Article

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