Fatty acids and sleep in UK children: Subjective and pilot objective sleep results from the DOLAB study - a randomized controlled trial

Journal of Sleep Research

Volumn 23, Issue 4, 2014, Pages 364-388

  Montgomery, Paul ^a   Burton, Jennifer R ^a   Sewell, Richard P ^a   Spreckelsen, Thees F ^a   Richardson, Alexandra J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Actigraphy; Children; Docosahexaenoic acid; Omega 3; Randomized controlled trial; Sleep

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; PLACEBO;

ACTIMETRY; ARTICLE; CHILD; CHILD SLEEP HABIT QUESTIONNAIRE; CHILDHOOD DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; ESSENTIAL FATTY ACID DEFICIENCY; EXPLORATORY RESEARCH; FATTY ACID BLOOD LEVEL; FEMALE; HUMAN; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP DISORDER; SUPPLEMENTATION; UNITED KINGDOM;

ACTIGRAPHY; CHILDREN; DOCOSAHEXAENOIC ACID; OMEGA-3; RANDOMIZED CONTROLLED TRIAL; SLEEP;

ACTIGRAPHY; CHILD; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS; FATTY ACIDS, OMEGA-3; FEMALE; GREAT BRITAIN; HEALTHY VOLUNTEERS; HUMANS; MALE; PARENTS; PILOT PROJECTS; QUESTIONNAIRES; SLEEP; SLEEP DISORDERS;

EID: 84904961169     PISSN: 09621105     EISSN: 13652869     Source Type: Journal    
DOI: 10.1111/jsr.12135     Document Type: Article

References (42)

1. Bailey-Hall, E., Nelson, E. B. and Ryan, A. S. Validation of a rapid measure of blood PUFA levels in humans. Lipids, 2008, 43: 181-186.
2. Bloch, M. H. and Qawasmi, A. Omega-3 fatty acid supplementation for the treatment of children with attention-deficit/hyperactivity disorder symptomatology: systematic review and meta-analysis. J. Am. Acad. Child Psychiatry, 2011, 50: 991-1000.
3. Burgess, J. R., Stevens, L., Zhang, W. and Peck, L. Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. Am. J. Clin. Nutr., 2000, 71(Suppl. 1): 327S-330S.
4. Catala, A. The function of very long chain polyunsaturated fatty acids in the pineal gland. Biochim. Biophys. Acta, 2010, 1801: 95-99.
5. Cheruku, S. R., Montgomery-Downs, H. E., Farkas, S. L., Thoman, E. B. and Lammi-Keefe, C. J. Higher maternal plasma docosahexaenoic acid during pregnancy is associated with more mature neonatal sleep-state patterning. Am. J. Clin. Nutr., 2002, 76: 608-613.
6. Cornu, C., Remontet, L., Noel-Baron, F., et al. A dietary supplement to improve the quality of sleep: a randomized placebo controlled trial. BMC Complement. Altern. Med., 2010, 10: 29.
7. Cortese, S., Faraone, S. V., Konofal, E. and Lecendreux, M. Sleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studies. J. Am. Acad. Child Adolesc. Psychiatry, 2009, 48: 894-908.
8. Department of Education Department of Education Special Educational Needs Code of Practice-DfES/581/2001. Department of Education, London, 2001.
9. Dewald, J. F., Meijer, A. M., Oort, F. J., Kerkhof, G. A. and Bogels, S. M. The influence of sleep quality, sleep duration and sleepiness on school performance in children and adolescents: a meta-analytic review. Sleep Med. Rev., 2010, 14: 179-189.
10. Edinger, J. D., Wohlgemuth, W. K., Radtke, R. A., Marsh, G. R. and Quillian, R. E. Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial. JAMA, 2001, 285: 1856-1864.
11. Harris, W. S. and Klurfeld, D. M. Twentieth-century trends in essential fatty acid intakes and the predicted omega-3 index: evidence versus estimates. Am. J. Clin. Nutr., 2011, 93: 907-908.
12. Huang, Z. L., Urade, Y. and Hayaishi, O. The role of adenosine in the regulation of sleep. Curr. Top. Med. Chem., 2011, 11: 1047-1057.
13. Huss, M., Volp, A. and Stauss-Grabo, M. Supplementation of polyunsaturated fatty acids, magnesium and zinc in children seeking medical advice for attention-deficit/hyperactivity problems-an observational cohort study. Lipids Health Dis., 2010, 9: 105.
14. Ichihara, K., Waku, K., Yamaguchi, C., et al. A convenient method for determination of the C20-22 PUFA composition of glycerolipids in blood and breast milk. Lipids, 2002, 37: 523-526.
15. Ivanhoe, J. R., Lefebvre, C. A. and Stockstill, J. W. Sleep disordered breathing in infants and children: a review of the literature. Pediatr. Dent., 2007, 29: 193-200.
16. Judge, M. P., Cong, X., Harel, O., Courville, A. B. and Lammi-Keefe, C. J. Maternal consumption of a DHA-containing functional food benefits infant sleep patterning: an early neurodevelopmental measure. Early Hum. Dev., 2012, 88: 531-537.
17. Kopasz, M., Loessl, B., Hornyak, M., et al. Sleep and memory in healthy children and adolescents-a critical review. Sleep Med. Rev., 2010, 14: 167-177.
18. Ladesich, J. B., Pottala, J. V., Romaker, A. and Harris, W. S. Membrane level of omega-3 docosahexaenoic acid is associated with severity of obstructive sleep apnea. J. Clin. Sleep Med., 2011, 7: 391-396.
19. Lavialle, M., Champeil-Potokar, G., Alessandri, J. M., et al. An (n-3) polyunsaturated fatty acid-deficient diet disturbs daily locomotor activity, melatonin rhythm, and striatal dopamine in Syrian hamsters. J. Nutr., 2008, 138: 1719-1724.
20. Liu, J., Zhang, A. and Li, L. Sleep duration and overweight/obesity in children: review and implications for pediatric nursing. J. Spec. Pediatr. Nurs., 2012, 17: 193-204.
21. Meltzer, L. J., Walsh, C. M., Traylor, J. and Westin, A. M. Direct comparison of two new actigraphs and polysomnography in children and adolescents. Sleep, 2012, 35: 159-166.
22. Montgomery, P., Burton, J. R., Sewell, R. P., Spreckelsen, T. F. and Richardson, A. J. Low blood long chain omega-3 fatty acids in UK children are associated with poor cognitive performance and behavior: a cross-sectional analysis from the DOLAB study. PLoS One, 2013, 8: e66697.
23. Owens, J. A., Spirito, A. and McGuinn, M. The Children's Sleep Habits Questionnaire (CSHQ): psychometric properties of a survey instrument for school-aged children. Sleep, 2000, 23: 1043-1051.
24. Papandreou, C. Independent associations between fatty acids and sleep quality among obese patients with obstructive sleep apnoea syndrome. J. Sleep Res., 2013, 22: 569-572.
25. Peuhkuri, K., Sihvola, N. and Korpela, R. Diet promotes sleep duration and quality. Nutr. Res., 2012, 32: 309-319.
26. Price, A. M., Wake, M., Ukoumunne, O. C. and Hiscock, H. Five-year follow-up of harms and benefits of behavioral infant sleep intervention: randomized trial. Pediatrics, 2012, 130: 643-651.
27. Richardson, A. J. Omega-3 fatty acids in ADHD and related neurodevelopmental disorders. Int. Rev. Psychiatry, 2006, 18: 155-172.
28. Richardson, A. J. and Montgomery, P. The Oxford-Durham study: a randomized, controlled trial of dietary supplementation with fatty acids in children with developmental coordination disorder. Pediatrics, 2005, 115: 1360-1366.
29. Richardson, A. J., Burton, J. R., Sewell, R. P., Spreckelsen, T. F. and Montgomery, P. Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 Years: a randomized, controlled trial (The DOLAB Study). PLoS One, 2012, 7: e43909.
30. Sadeh, A., Sharkey, K. M. and Carskadon, M. A. Activity-based sleep-wake identification: an empirical test of methodological issues. Sleep, 1994, 17: 201-207.
31. Smaldone, A., Honig, J. C. and Byrne, M. W. Sleepless in America: inadequate sleep and relationships to health and well-being of our nation's children. Pediatrics, 2007, 119(Suppl. 1): S29-S37.
32. Standards and Testing Agency National Curriculum Teacher Assessments and Key Stage Tests. Department of Education, London, 2009.
33. Stevens, L. J., Zentall, S. S., Deck, J. L., et al. Essential fatty acid metabolism in boys with attention-deficit hyperactivity disorder. Am. J. Clin. Nutr., 1995, 62: 761-768.
34. Tan, M. L., Ho, J. J. and Teh, K. H. Polyunsaturated fatty acids (PUFAs) for children with specific learning disorders. Cochrane Database Syst. Rev., 2012, 12: CD009398.
35. Tilmanne, J., Urbain, J., Kothare, M. V., Wouwer, A. V. and Kothare, S. V. Algorithms for sleep-wake identification using actigraphy: a comparative study and new results. J. Sleep Res., 2009, 18: 85-98.
36. Urade, Y. and Hayaishi, O. Prostaglandin D2 and sleep/wake regulation. Sleep Med. Rev., 2011, 15: 411-418.
37. Weiss, M. D., Wasdell, M. B., Bomben, M. M., Rea, K. J. and Freeman, R. D. Sleep hygiene and melatonin treatment for children and adolescents with ADHD and initial insomnia. J. Am. Acad. Child Adolesc. Psychiatry, 2006, 45: 512-519.
38. Wiggs, L., Montgomery, P. and Stores, G. Actigraphic and parent reports of sleep patterns and sleep disorders in children with subtypes of attention-deficit hyperactivity disorder. Sleep, 2005, 28: 1437-1445.
39. Yehuda, S., Rabinovitz, S. and Mostofsky, D. I. Essential fatty acids and sleep: mini-review and hypothesis. Med. Hypotheses, 1998, 50: 139-145.
40. Yehuda, S., Rabinovitz-Shenkar, S. and Carasso, R. L. Effects of essential fatty acids in iron deficient and sleep-disturbed attention deficit hyperactivity disorder (ADHD) children. Eur. J. Clin. Nutr., 2011, 65: 1167-1169.
41. Zaouali-Ajina, M., Gharib, A., Durand, G., et al. Dietary docosahexaenoic acid-enriched phospholipids normalize urinary melatonin excretion in adult (n-3) polyunsaturated fatty acid-deficient rats. J. Nutr., 1999, 129: 2074-2080.
42. Zhang, H., Hamilton, J. H., Salem, N. Jr and Kim, H. Y. N-3 fatty acid deficiency in the rat pineal gland: effects on phospholipid molecular species composition and endogenous levels of melatonin and lipoxygenase products. J. Lipid Res., 1998, 39: 1397-1403.