In vivo optical imaging of folate receptor-β in head and neck squamous cell carcinoma

Laryngoscope

Volumn 124, Issue 8, 2014, Pages

  Sun, Joel Y ^a   Shen, Jiayin ^b   Thibodeaux, Joel ^a   Huang, Gang ^a   Wang, Yiguang ^a   Gao, Jinming ^a   Low, Philip S ^b   Dimitrov, Dimiter S ^c   Sumer, Baran D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b PURDUE UNIVERSITY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

fluorescence; folate receptor; Head and neck; optical imaging; squamous cell carcinoma; tumor associated macrophages

Indexed keywords

CD206 ANTIGEN; CD45 ANTIGEN; CHLORDANE; FLUORESCEIN ISOTHIOCYANATE; FOLATE RECEPTOR 2; LEUKOCYTE ANTIGEN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER CELL; CELL INFILTRATION; CONFERENCE PAPER; CONTROLLED STUDY; EX VIVO STUDY; FLOW CYTOMETRY; FLUORESCENCE IMAGING; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INFLAMMATORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; TISSUE MICROARRAY; TUMOR ASSOCIATED LEUKOCYTE; TUMOR XENOGRAFT;

FLUORESCENCE; FOLATE RECEPTOR; HEAD AND NECK; OPTICAL IMAGING; SQUAMOUS CELL CARCINOMA; TUMOR-ASSOCIATED MACROPHAGES;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CARCINOMA, SQUAMOUS CELL; FEMALE; FOLATE RECEPTOR 1; FOLATE RECEPTOR 2; HEAD AND NECK NEOPLASMS; HUMANS; MICE; MIDDLE AGED; NEOPLASM PROTEINS; OPTICAL IMAGING; RETROSPECTIVE STUDIES;

EID: 84904767680     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.24606     Document Type: Conference Paper

References (31)

1. American Cancer Society. Cancer Facts & Figures 2012. Atlanta, GA: American Cancer Society; 2012.
2. Bernier J, Domenge C, Ozsahin M, et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004; 350: 1945-1952.
3. Hadjipanayis CG, Jiang H, Roberts DW, Yang L,. Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening. Semin Oncol 2011; 38: 109-118.
4. Rosenthal EL, Kulbersh BD, Duncan RD, et al. In vivo detection of head and neck cancer orthotopic xenografts by immunofluorescence. Laryngoscope 2006; 116: 1636-1641.
5. Heath CH, Deep NL, Sweeny L, Zinn KR, Rosenthal EL,. Use of panitumumab-IRDye800 to image microscopic head and neck cancer in an orthotopic surgical model. Ann Surg Oncol 2012; 19: 3879-3887.
6. Nguyen QT, Olson ES, Aguilera TA, et al. Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci USA 2009; 107: 4317-4322.
7. Looser KG, Shah JP, Strong EW,. The significance of "positive" margins in surgically resected epidermoid carcinomas. Head Neck 1978; 1: 107-111.
8. McMahon J, O'Brien CJ, Pathak I, et al. Influence of condition of surgical margins on local recurrence and disease-specific survival in oral and oropharyngeal cancer. Br J Oral Maxillofac Surg 2003; 41: 224-231.
9. van Dam GM, Themelis G, Crane LMA, et al. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med 2011; 17: 1315-1319.
10. Keereweer S, Mieog JD, Mol IM, et al. Detection of oral squamous cell carcinoma and cervical lymph node metastasis using activatable near-infrared fluorescence agents. Arch Otolaryngol Head Neck Surg 2011; 137: 609-615.
11. Salazar MD, Ratnam M,. The folate receptor: what does it promise in tissue-targeted therapeutics? Cancer Metastasis Rev 2007; 26: 141-152.
12. Parker N, Turk M, Westrick E, Lewis JD, Low PS, Leamon CP,. Folate receptor expression in carcinomas and normal tissues determined by a quantitative radio-ligand binding assay. Anal Biochem 2005; 338: 284-293.
13. Kalli KR, Oberg AL, Keeney GL, et al. Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol 2008; 108: 619-626.
14. Cagle PT, Zhai Q, Murphy L, Low PS,. Folate Receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents. Arch Pathol Lab Med 2013; 137: 241-244.
15. Ross JF, Wang H, Behm FG, et al. Folate receptor type β is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia. Cancer 1999; 85: 348-357.
16. Ross JF, Chaudhuri PK, Ratnam M,. Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Cancer 1994; 73: 2432-2443.
17. Saba NF, Wang X, Muller S, et al. Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug. Head Neck 2009; 31: 475-481.
18. O'Shannessy DJ, Yu G, Smale R, et al. Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance. Oncotarget 2012; 3: 414-425.
19. Feng Y, Shen J, Streaker ED, et al. A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity. Arthritis Res Ther 2011; 13: R59.
20. Heusinkveld M, van der Burg SH,. Identification and manipulation of tumor associated macrophages in human cancers. J Transl Med 2011; 9: 216.
21. Wei X, Hilgenbrink AR, Matteson EL, Lockwood MB, Cheng J, Low PS,. A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages. Blood 2009; 113: 438-446.
22. Puig-Kroger A, Sierra-Filardi E, Dominguez-Soto A, et al. Folate receptor β is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages. Cancer Res 2009; 69: 9395-9403.
23. Kurahara H, Takao S, Kuwahata T, et al. Clinical significance of folate receptor β-expressing tumor-associated macrophages in pancreatic cancer. Ann Surg Oncol 2012; 19: 2264-2271.
24. Coussens LM, Werb Z,. Inflammation and cancer. Nature 2002; 420: 860-867.
25. Allavena P, Sica A, Garlanda C, Mantovani A,. The yin-yang of tumor associated macrophages in neoplastic progression and immune surveillance. Immunol Rev 2008; 222: 155-161.
26. Jones MB, Neuper C, Clayton A, et al. Rationale for folate receptor alpha targeted therapy in "high risk" endometrial carcinomas. Int J Cancer 2008; 123: 1699-1703.
27. Schoppmann SF, Fenzl A, Nagy K, et al. VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival. Surgery 2003; 139: 839-846.
28. Kurahara H, Takao S, Maemura K, et al. M2-polarized tumor-associated macrophage infiltration of regional lymph nodes is associated with nodal lymphangiogenesis and occult nodal involvement in pN0 pancreatic cancer. Pancreas 2013; 42: 155-159.
29. University of Alabama at Birmingham. Cetuximab IRDye800 study as an optical imaging agent to detect cancer during surgical procedures. ClinicalTrials website. Available at: http://clinicaltrials.gov/ct2/show/ NCT01987375. Updated November 12, 2013. Accessed December 29, 2013.
30. University Medical Centre Groningen, Dutch Cancer Society. Visualization of rectal cancer during endoscopy, using a fluorescent tracer (RAPIDO-TRACT). ClinicalTrials website. Available at: http://clinicaltrials.gov/show/ NCT01972373. Updated October 24, 2013. Accessed December 29, 2013.
31. Kelderhouse LE, Chelvam V, Wayua C, et al. Development of tumor-targeted near infrared probes for fluorescence guided surgery. Bioconjug Chem. 2013; 24: 1075-1080.