PTEN mutations and activation of the PI3K/Akt/mTOR signaling pathway in papillary tumors of the pineal region

Journal of Neuropathology and Experimental Neurology

Volumn 73, Issue 8, 2014, Pages 747-751

  Goschzik, Tobias ^a   Gessi, Marco ^a   Denkhaus, Dorota ^a   Pietsch, Torsten ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Homozygous deletion; Molecular inversion probe analysis; Mutations; Papillary tumors of the pineal region; PI3K Akt mTOR signaling pathway; PTEN

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN S6;

ADOLESCENT; ADULT; ARTICLE; BRAIN METASTASIS; CHROMOSOME 10; CHROMOSOME 12; CHROMOSOME 14; CHROMOSOME 22; CHROMOSOME 3; CHROMOSOME 8; CHROMOSOME 9; CHROMOSOME LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DISTANT METASTASIS; ENZYME ACTIVATION; EXON; FEMALE; GENE DELETION; GENE MUTATION; GENE SEQUENCE; HOMOZYGOTE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR BIOLOGY; MOLECULAR INVERSION PROBE ANALYSIS; MUTATIONAL ANALYSIS; PAPILLARY TUMORS OF THE PINEAL REGION; PAPILLOMA; PINEAL BODY TUMOR; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PTEN GENE; SIGNAL TRANSDUCTION; SPINAL CORD METASTASIS; TUMOR SUPPRESSOR GENE; X CHROMOSOME;

ADOLESCENT; ADULT; BRAIN NEOPLASMS; FEMALE; HUMANS; KERATINS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; MUCIN-1; MUTATION; NEOPLASMS, NEUROEPITHELIAL; NERVE TISSUE PROTEINS; PINEAL GLAND; PINEALOMA; PTEN PHOSPHOHYDROLASE; S100 PROTEINS; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84904764532     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0000000000000093     Document Type: Article

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