Protective role of 5-azacytidine on myocardial infarction is associated with modulation of macrophage phenotype and inhibition of fibrosis

Journal of Cellular and Molecular Medicine

Volumn 18, Issue 6, 2014, Pages 1018-1027

  Kim, Yong Sook ^a   Kang, Wan Seok ^a,b   Kwon, Jin Sook ^a   Hong, Moon Hwa ^a   Jeong, Hye yun ^a,b   Jeong, Hae Chang ^a   Jeong, Myung Ho ^a   Ahn, Youngkeun ^a  

^a Chonnam National University Medical School   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

5 azacytidine; Inducible nitric oxide synthase; Macrophage; Myocardial infarction

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; AZACITIDINE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEPTIDOGLYCAN;

ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; DRUG EFFECTS; DRUG THERAPY; ENZYME IMMUNOASSAY; FIBROBLAST; FIBROSIS; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE REMODELING; MACROPHAGE; MALE; METABOLISM; MOUSE; MYOCARDIAL INFARCTION; PATHOLOGY; PHENOTYPE; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; BLOTTING, WESTERN; CELLS, CULTURED; FIBROBLASTS; FIBROSIS; IMMUNOENZYME TECHNIQUES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MYOCARDIAL INFARCTION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEPTIDOGLYCAN; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84904763727     PISSN: 15821838     EISSN: 15824934     Source Type: Journal    
DOI: 10.1111/jcmm.12248     Document Type: Article

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