OCT-1 overexpression is associated with poor prognosis in patients with well-differentiated gastric cancer

Tumor Biology

Volumn 35, Issue 6, 2014, Pages 5501-5509

  Jeong, Sang Ho ^a   Lee, Young Joon ^a   Cho, Bok Im ^a   Ha, Woo Song ^a   Choi, Sang Kyung ^a   Jung, Eun Jung ^a   Ju, Young Tae ^a   Jeong, Chi Young ^a   Ko, Gyung Hyuck ^a   Yoo, Jiyun ^a   Hong, Soon Chan ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Biomarker; Immunohistochemistry; OCT 1; Octamer transcription factor 1; Stomach neoplasm

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 1;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GAIN OF FUNCTION MUTATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PRIORITY JOURNAL; STOMACH CANCER; SURVIVAL RATE; TUMOR INVASION; WORLD HEALTH ORGANIZATION;

AGED; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; OCTAMER TRANSCRIPTION FACTOR-1; PROGNOSIS; STOMACH NEOPLASMS;

EID: 84904755413     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1724-4     Document Type: Article

References (24)

1. Lee HJ, Yang HK, Ahn YO. Gastric cancer in Korea. Gastric Cancer. 2002;5:177-82.
2. Townscend CM. Sabiston textbook of surgery. Elservier Inc.: Philadelphia; 2008.
3. Korean Surgical Society. Text book of surgery. Koonja, Seoul; 2011.
4. Tamura G. Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. World J Gastroenterol. 2006;12:192-8. (Pubitemid 43336916)
5. Griffiths EA, Pritchard SA, Valentine HR, Whitchelo N, Bishop PW, Ebert MP, et al. Hypoxia-inducible factor-1alpha expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas. Br J Cancer. 2007;96:95-103. (Pubitemid 46094645)
6. Smith MG, Hold GL, Tahara E, El-Omar EM. Cellular and molecular aspects of gastric cancer. World J Gastroenterol. 2006;12:2979-90. (Pubitemid 43811073)
7. Beswick EJ, Bland DA, Suarez G, Barrera CA, Fan X, Reyes VE. Helicobacter pylori binds to cd74 on gastric epithelial cells and stimulates interleukin-8 production. Infect Immun. 2005;73:2736-43. (Pubitemid 40570339)
8. Holmes K, Egan B, Swan N, O'Morain C. Genetic mechanisms and aberrant gene expression during the development of gastric intestinal metaplasia and adenocarcinoma. Curr Genomics. 2007;8:379-97. (Pubitemid 351472406)
9. Almeida R, Silva E, Santos-Silva F, Silberg DG, Wang J, De Bolos C, et al. Expression of intestine-specific transcription factors, cdx1 and cdx2, in intestinal metaplasia and gastric carcinomas. J Pathol. 2003;199:36-40. (Pubitemid 36054727)
10. Almeida R, Almeida J, Shoshkes M, Mendes N, Mesquita P, Silva E, et al. Oct-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, cdx2 in gastric cells. J Pathol. 2005;207:396-401. (Pubitemid 43025687)
11. Verrijzer CP, Van der Vliet PC. Pou domain transcription factors. Biochim Biophys Acta. 1993;1173:1-21. (Pubitemid 23125489)
12. Kimura M, Tsuda H, Morita D, Ichikura T, Ogata S, Aida S, et al. A proposal for diagnostically meaningful criteria to classify increased epidermal growth factor receptor and c-erbb-2 gene copy numbers in gastric carcinoma, based on correlation of fluorescence in situ hybridization and immunohistochemical measurements. Virchows Arch. 2004;445:255-62. (Pubitemid 39286893)
13. Lorentz O, Duluc I, Arcangelis AD, Simon-Assmann P, Kedinger M, Freund JN. Key role of the cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation. J Cell Biol. 1997;139:1553-65. (Pubitemid 28013675)
14. Suh E, Traber PG. An intestine-specific homeobox gene regulates proliferation and differentiation. Mol Cell Biol. 1996;16:619-25. (Pubitemid 26029101)
15. Seno H, Oshima M, Taniguchi MA, Usami K, Ishikawa TO, Chiba T, et al. Cdx2 expression in the stomach with intestinal metaplasia and intestinal-type cancer: prognostic implications. Int J Oncol. 2002;21:769-74.
16. Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, et al. Oct1 regulates trophoblast development during early mouse embryogenesis. Development. 2010;137:3551-60.
17. Shakya A, Kang J, Chumley J, Williams MA, Tantin D. Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states. J Biol Chem. 2011;286:450-9.
18. Wang P, Wang Q, Sun J, Wu J, Li H, Zhang N, et al. Pou homeodomain protein oct-1 functions as a sensor for cyclic amp. J Biol Chem. 2009;284:26456-65.
19. Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varambally R, Yu J, Briggs BB, et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia. 2007;9:166-80.
20. Zhou C, Tong Y, Wawrowsky K, Bannykh S, Donangelo I, Melmed S. Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors. Endocr Relat Cancer. 2008;15:817-31.
21. Wang VE, Tantin D, Chen J, Sharp PA. B cell development and immunoglobulin transcription in oct-1-deficient mice. Proc Natl Acad Sci U S A. 2004;101:2005-10. (Pubitemid 38229005)
22. Tantin D, Schild-Poulter C, Wang V, Hache RJ, Sharp PA. The octamer binding transcription factor oct-1 is a stress sensor. Cancer Res. 2005;65:10750-8. (Pubitemid 41713343)
23. Shakya A, Cooksey R, Cox JE, Wang V, McClain DA, Tantin D. Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity. Nat Cell Biol. 2009;11:320-7.
24. Maddox J, Shakya A, South S, Shelton D, Andersen JN, Chidester S, et al. Transcription factor oct1 is a somatic and cancer stem cell determinant. PLoS Genet. 2012;8:e1003048.