메뉴 건너뛰기




Volumn 35, Issue 6, 2014, Pages 5551-5560

Prognostic role of circulating tumor cells and disseminated tumor cells in patients with prostate cancer: A systematic review and meta-analysis

Author keywords

Bone marrow; Circulating tumor cell; Metastasis; Prognosis; Prostate cancer

Indexed keywords

BIOLOGICAL MARKER;

EID: 84904753867     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1731-5     Document Type: Review
Times cited : (60)

References (52)
  • 2
    • 0036559864 scopus 로고    scopus 로고
    • A history of prostate cancer treatment
    • Denmeade SR, Isaacs JT. A history of prostate cancer treatment. Nat Rev Cancer. 2002;2:389-96. (Pubitemid 37328952)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.5 , pp. 389-396
    • Denmeade, S.R.1    Isaacs, J.T.2
  • 3
    • 0025295790 scopus 로고
    • Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen
    • Cooner WH, Mosley BR, Rutherford Jr CL, Beard JH, Pond HS, Terry WJ, et al. Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen. J Urol. 1990;143:1144-6.
    • (1990) J Urol , vol.143 , pp. 1144-1146
    • Cooner, W.H.1    Mosley, B.R.2    Rutherford Jr., C.L.3    Beard, J.H.4    Pond, H.S.5    Terry, W.J.6
  • 4
    • 33646489152 scopus 로고    scopus 로고
    • Diagnostic value of systematic biopsymethods in the investigation of prostate cancer: A systematic review
    • Eichler K, Hempel S, Wilby J, Myers L, Bachmann LM, Kleijnen J. Diagnostic value of systematic biopsymethods in the investigation of prostate cancer: a systematic review. J Urol. 2006;175:1605-12.
    • (2006) J Urol , vol.175 , pp. 1605-1612
    • Eichler, K.1    Hempel, S.2    Wilby, J.3    Myers, L.4    Bachmann, L.M.5    Kleijnen, J.6
  • 5
    • 78649362120 scopus 로고    scopus 로고
    • Eau guidelines on prostate cancer. Part 1: Screening, diagnosis, and treatment of clinically localised disease
    • Heidenreich A, Bellmunt J, Bolla M, Joniau S, Mason M, Matveev V, et al. Eau guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease. Eur Urol. 2011;59:61-71.
    • (2011) Eur Urol , vol.59 , pp. 61-71
    • Heidenreich, A.1    Bellmunt, J.2    Bolla, M.3    Joniau, S.4    Mason, M.5    Matveev, V.6
  • 6
    • 0000110505 scopus 로고
    • A case of cancer in which cells similar to those in the tumours were seen in the blood after death
    • Ashworth TR. A case of cancer in which cells similar to those in the tumours were seen in the blood after death. Aust Med J. 1869;14:146-9.
    • (1869) Aust Med J , vol.14 , pp. 146-149
    • Ashworth, T.R.1
  • 8
    • 84867556074 scopus 로고    scopus 로고
    • Meta-analysis of the prognostic value of circulating tumor cells in breast cancer
    • Zhang L, Riethdorf S, Wu G, Wang T, Yang K, Peng G, et al. Meta-analysis of the prognostic value of circulating tumor cells in breast cancer. Clin Cancer Res. 2012;18:5701-10.
    • (2012) Clin Cancer Res , vol.18 , pp. 5701-5710
    • Zhang, L.1    Riethdorf, S.2    Wu, G.3    Wang, T.4    Yang, K.5    Peng, G.6
  • 11
    • 58949088650 scopus 로고    scopus 로고
    • Circulating tumour cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): A single-centre experience
    • Olmos D, Arkenau H, Ang JE, Ledaki I, Attard G, Carden CP, et al. Circulating tumour cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): a single-centre experience. Ann Oncol. 2009;20:27-33.
    • (2009) Ann Oncol , vol.20 , pp. 27-33
    • Olmos, D.1    Arkenau, H.2    Ang, J.E.3    Ledaki, I.4    Attard, G.5    Carden, C.P.6
  • 12
    • 0029867674 scopus 로고    scopus 로고
    • Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases
    • DOI 10.1016/S0140-6736(96)91203-9
    • Pantel K, Izbicki J, Passlick B, Angstwurm M, Haussinger K, Thetter O, et al. Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet. 1996;347:649-53. (Pubitemid 26076131)
    • (1996) Lancet , vol.347 , Issue.9002 , pp. 649-653
    • Pantel, K.1    Izbicki, J.2    Passlick, B.3    Angstwurm, M.4    Haussinger, K.5    Thetter, O.6    Riethmuller, G.7
  • 13
    • 57049162148 scopus 로고    scopus 로고
    • Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial
    • Pierga J-Y, Bidard F-C, Mathiot C, Brain E, Delaloge S, Giachetti S, et al. Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial. Clin Cancer Res Off J Am Assoc Cancer Res. 2008;14:7004-10.
    • (2008) Clin Cancer Res off J Am Assoc Cancer Res , vol.14 , pp. 7004-7010
    • Pierga, J.-Y.1    Bidard, F.-C.2    Mathiot, C.3    Brain, E.4    Delaloge, S.5    Giachetti, S.6
  • 15
    • 17444434615 scopus 로고    scopus 로고
    • Prognostic significance of detection of prostate-specific antigen transcripts in the peripheral blood of patients with metastatic androgen-independent prostatic
    • Ghossein R, Rosai J, Scher H, Seiden M. Prognostic significance of detection of prostate-specific antigen transcripts in the peripheral blood of patients with metastatic androgen-independent prostatic. Urology. 1997;4295:100-5.
    • (1997) Urology , vol.4295 , pp. 100-105
    • Ghossein, R.1    Rosai, J.2    Scher, H.3    Seiden, M.4
  • 16
    • 67449107298 scopus 로고    scopus 로고
    • Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors
    • Goodman OB, Fink LM, Symanowski JT, Wong B, Grobaski B, Pomerantz D, et al. Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors. Cancer Epidemiol Biomark Prev. 2009;18:1904-13.
    • (2009) Cancer Epidemiol Biomark Prev , vol.18 , pp. 1904-1913
    • Goodman, O.B.1    Fink, L.M.2    Symanowski, J.T.3    Wong, B.4    Grobaski, B.5    Pomerantz, D.6
  • 18
    • 0036282360 scopus 로고    scopus 로고
    • Reverse transcription-polymerase chain reaction detection of prostate-specific antigen, prostate-specific membrane antigen, and prostate stem cell antigen in one milliliter of peripheral blood: Value for the staging of prostate cancer
    • Hara N, Kasahara T, Kawasaki T. Reverse transcription-polymerase chain reaction detection of prostate-specific antigen, prostate-specific membrane antigen, and prostate stem cell antigen in one milliliter of peripheral blood: value for the staging of prostate cancer. Clin Cancer Res. 2002;8:1794-9. (Pubitemid 34633737)
    • (2002) Clinical Cancer Research , vol.8 , Issue.6 , pp. 1794-1799
    • Hara, N.1    Kasahara, T.2    Kawasaki, T.3    Bilim, V.4    Obara, K.5    Takahashi, K.6    Tomita, Y.7
  • 19
    • 76549107118 scopus 로고    scopus 로고
    • Prostate stem cell antigen mRNA in peripheral blood as a potential predictor of biochemical recurrence in high-risk prostate cancer
    • Joung JAEY, Cho KSU, Kim JEUN, Seo HOK, Chung J, Park WSEO, et al. Prostate stem cell antigen mRNA in peripheral blood as a potential predictor of biochemical recurrence in high-risk prostate cancer. J Surg Oncol. 2010;101:145-8.
    • (2010) J Surg Oncol , vol.101 , pp. 145-148
    • Joung, J.A.E.Y.1    Cho, K.S.U.2    Kim, J.E.U.N.3    Seo, H.O.K.4    Chung, J.5    Park, W.S.E.O.6
  • 20
    • 35648945945 scopus 로고    scopus 로고
    • Combined androgen blockade therapy can convert RT-PCR detection of prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) transcripts
    • Lembessis P, Msaouel P. Combined androgen blockade therapy can convert RT-PCR detection of prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) transcripts. Clin Chem Lab Med. 2007;45:1488-94.
    • (2007) Clin Chem Lab Med , vol.45 , pp. 1488-1494
    • Lembessis, P.1    Msaouel, P.2
  • 21
    • 17144426134 scopus 로고    scopus 로고
    • Circulating tumor cells predict survival in patients with metastatic prostate cancer
    • DOI 10.1016/j.urology.2004.11.006
    • Moreno J, Miller M, Gross S, Allard W. Circulating tumor cells predict survival in patients with metastatic prostate cancer. Urology. 2005;65:713-8. (Pubitemid 40523005)
    • (2005) Urology , vol.65 , Issue.4 , pp. 713-718
    • Moreno, J.G.1    Miller, M.C.2    Gross, S.3    Allard, W.J.4    Gomella, L.G.5    Terstappen, L.W.M.M.6
  • 22
    • 50949132840 scopus 로고    scopus 로고
    • Immunomagnetic quantification of circulating tumor cells as a prognostic factor of androgen deprivation responsiveness in patients with hormone naive metastatic
    • Okegawa T, Nutahara K, Higashihara E. Immunomagnetic quantification of circulating tumor cells as a prognostic factor of androgen deprivation responsiveness in patients with hormone naive metastatic. J Urol. 2008;180:1342-7.
    • (2008) J Urol , vol.180 , pp. 1342-1347
    • Okegawa, T.1    Nutahara, K.2    Higashihara, E.3
  • 23
    • 77951274075 scopus 로고    scopus 로고
    • Original article: Clinical investigation association of circulating tumor cells with tumor-related methylated DNA in patients with hormone-refractory
    • Okegawa T, Nutahara K, Higashihara E. Original article: clinical investigation association of circulating tumor cells with tumor-related methylated DNA in patients with hormone-refractory. Int J Urol. 2010;17:466-75.
    • (2010) Int J Urol , vol.17 , pp. 466-475
    • Okegawa, T.1    Nutahara, K.2    Higashihara, E.3
  • 24
    • 59349109415 scopus 로고    scopus 로고
    • Prognostic significance of circulating tumor cells in patients with hormone refractory prostate cancer
    • Okegawa T, Nutahara K, Higashihara E. Prognostic significance of circulating tumor cells in patients with hormone refractory prostate cancer. J Urol. 2009;181:1091-7.
    • (2009) J Urol , vol.181 , pp. 1091-1097
    • Okegawa, T.1    Nutahara, K.2    Higashihara, E.3
  • 25
    • 0029918964 scopus 로고    scopus 로고
    • Preoperative reverse transcriptase polymerase chain reaction for prostate specific antigen predicts treatment failure following radical prostatectomy
    • DOI 10.1016/S0022-5347(01)66125-1
    • Olsson CA, Vries GMDE, Raffo AJ, Benson MC, Otoole K, Cao Y, et al. Preoperative reverse transcriptase polymerase chain reaction for prostate specific antigen predicts treatment failure following radical prostatectomy. J Urol. 1996;155:1557-62. (Pubitemid 26126948)
    • (1996) Journal of Urology , vol.155 , Issue.5 , pp. 1557-1562
    • Olsson, C.A.1    De Vries, G.M.2    Raffo, A.J.3    Benson, M.C.4    O'Toole, K.5    Cao, Y.6    Buttyan, R.E.7    Katz, A.E.8
  • 26
    • 62849099048 scopus 로고    scopus 로고
    • Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer: A reanalysis of IMMC38 trial data
    • Scher HI, Jia X, Bono JSD, Fleisher M, Pienta KJ, Raghavan D, et al. Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer : a reanalysis of IMMC38 trial data. Lancet Oncol. 2009;10:233-9.
    • (2009) Lancet Oncol , vol.10 , pp. 233-239
    • Scher, H.I.1    Jia, X.2    Bono, J.S.D.3    Fleisher, M.4    Pienta, K.J.5    Raghavan, D.6
  • 27
    • 77954218253 scopus 로고    scopus 로고
    • Circulating endothelial cells, circulating tumour cells, tissue factor, endothelin-1 and overall survival in prostate cancer patients treated with docetaxel
    • Strijbos MH, Gratama JW, Schmitz PIM, Rao C, Onstenk W, Doyle GV, et al. Circulating endothelial cells, circulating tumour cells, tissue factor, endothelin-1 and overall survival in prostate cancer patients treated with docetaxel. Eur J Cancer. 2010;46:2027-35.
    • (2010) Eur J Cancer , vol.46 , pp. 2027-2035
    • Strijbos, M.H.1    Gratama, J.W.2    Schmitz, P.I.M.3    Rao, C.4    Onstenk, W.5    Doyle, G.V.6
  • 28
    • 67650457467 scopus 로고    scopus 로고
    • Urokinase-plasminogen-activator receptor expression in desseminated tumour cells in the bone marrow and peripheral blood of patients with clinically localized prostate cancer
    • Thomas C, Wiesner C, Melchior SW, Schmidt F, Gillitzer R, Thüroff JW, et al. Urokinase-plasminogen-activator receptor expression in desseminated tumour cells in the bone marrow and peripheral blood of patients with clinically localized prostate cancer. Int Br J Urol. 2008;104:29-34.
    • (2008) Int Br J Urol , vol.104 , pp. 29-34
    • Thomas, C.1    Wiesner, C.2    Melchior, S.W.3    Schmidt, F.4    Gillitzer, R.5    Thüroff, J.W.6
  • 29
    • 63749083366 scopus 로고    scopus 로고
    • Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer
    • Weckermann D, Polzer B, Ragg T, Blana A, Bertz S, Harzmann R, et al. Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer. J Clin Oncol. 2009;27:1549-56.
    • (2009) J Clin Oncol , vol.27 , pp. 1549-1556
    • Weckermann, D.1    Polzer, B.2    Ragg, T.3    Blana, A.4    Bertz, S.5    Harzmann, R.6
  • 31
    • 84870674044 scopus 로고    scopus 로고
    • Prognostic significance of circulating tumor cell count in patients with metastatic hormone-sensitive prostate cancer
    • Resel Folkersma L, San José Manso L, Galante Romo I, Moreno Sierra J, Olivier Gómez C. Prognostic significance of circulating tumor cell count in patients with metastatic hormone-sensitive prostate cancer. Urology. 2012;80:1328-32.
    • (2012) Urology , vol.80 , pp. 1328-1332
    • Resel Folkersma, L.1    San José Manso, L.2    Galante Romo, I.3    Moreno Sierra, J.4    Olivier Gómez, C.5
  • 32
    • 0342710328 scopus 로고    scopus 로고
    • Presence of circulating prostate cells in the bone marrow of patients undergoing radical prostatectomy is predictive of disease-free survival
    • Wood Jr DP, Banerjee M. Presence of circulating prostate cells in the bone marrow of patients undergoing radical prostatectomy is predictive of disease-free survival. J Clin Oncol Off J Am Soc Clin Oncol. 1997;15:3451-7. (Pubitemid 27527717)
    • (1997) Journal of Clinical Oncology , vol.15 , Issue.12 , pp. 3451-3457
    • Wood Jr., D.P.1    Banerjee, M.2
  • 33
    • 33947098505 scopus 로고    scopus 로고
    • Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy
    • DOI 10.1002/ijc.22488
    • Berg A, Berner A, Lilleby W, Bruland ØS, Foss SD. Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy. Int J Cancer. 2007;120:1603-9. (Pubitemid 46399343)
    • (2007) International Journal of Cancer , vol.120 , Issue.8 , pp. 1603-1609
    • Berg, A.1    Berner, A.2    Lilleby, W.3    Bruland, O.S.4    Fossa, S.D.5    Nesland, J.M.6    Kvalheim, G.7
  • 34
    • 0038301123 scopus 로고    scopus 로고
    • RT-PCR for PSA as a prognostic factor for patients with clinically localized prostate cancer treated with radiotherapy
    • DOI 10.1016/S0090-4295(02)02581-5
    • Gewanter R, Katz A, Olsson C. RT-PCR for PSA as a prognostic factor for patients with clinically localized prostate cancer treated with radiotherapy. Urology. 2003;4295:967-71. (Pubitemid 36547740)
    • (2003) Urology , vol.61 , Issue.5 , pp. 967-971
    • Gewanter, R.M.1    Katz, A.E.2    Olsson, C.A.3    Benson, M.C.4    Singh, A.5    Schiff, P.B.6    Ennis, R.D.7
  • 36
    • 0032849817 scopus 로고    scopus 로고
    • Clinical and molecular followup after radical retropubic prostatectomy
    • Oefelein M, Ignatoff J. Clinical and molecular followup after radical retropubic prostatectomy. J Urol. 1999;162:307-10.
    • (1999) J Urol , vol.162 , pp. 307-310
    • Oefelein, M.1    Ignatoff, J.2
  • 37
    • 0037108865 scopus 로고    scopus 로고
    • Preoperative blood reverse transcriptase-PCR assays for prostate-specific antigen and human glandular kallikrein for prediction of prostate cancer progression after radical prostatectomy
    • Shariat S, Gottenger E, Nguyen C. Reverse transcriptase-PCR assays for prostate-specific antigen and human glandular kallikrein for prediction of prostate cancer progression after radical prostatectomy. Cancer Res. 2002;62:5974-9. (Pubitemid 35204762)
    • (2002) Cancer Research , vol.62 , Issue.20 , pp. 5974-5979
    • Shariat, S.F.1    Gottenger, E.2    Nguyen, C.3    Song, W.4    Kattan, M.W.5    Andenoro, J.6    Wheeler, T.M.7    Spencer, D.M.8    Slawin, K.M.9
  • 38
    • 34547450763 scopus 로고    scopus 로고
    • Practical methods for incorporating summary time-to-event data into meta-analysis
    • Tierney JF, Stewart L, Ghersi D, Burdett S, Sydes MR. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials. 2007;8:16.
    • (2007) Trials , vol.8 , pp. 16
    • Tierney, J.F.1    Stewart, L.2    Ghersi, D.3    Burdett, S.4    Sydes, M.R.5
  • 40
    • 33845571913 scopus 로고    scopus 로고
    • Random-effects model for meta-analysis of clinical trials: An update
    • DOI 10.1016/j.cct.2006.04.004, PII S1551714406000486
    • DerSimonian R, Kacker R. Random-effects model for meta-analysis of clinical trials: an update. Contemporary Clinical Trials. 2007;28:105-14. (Pubitemid 44937874)
    • (2007) Contemporary Clinical Trials , vol.28 , Issue.2 , pp. 105-114
    • DerSimonian, R.1    Kacker, R.2
  • 42
    • 59449087476 scopus 로고    scopus 로고
    • Disseminated tumor cells in prostate cancer patients after radical prostatectomy and without evidence of disease predicts biochemical recurrence
    • Morgan TM, Lange PH, Porter MP, Lin DW, Ellis WJ, Gallaher IS, et al. Disseminated tumor cells in prostate cancer patients after radical prostatectomy and without evidence of disease predicts biochemical recurrence. Clin Cancer Res. 2009;15:677-83.
    • (2009) Clin Cancer Res , vol.15 , pp. 677-683
    • Morgan, T.M.1    Lange, P.H.2    Porter, M.P.3    Lin, D.W.4    Ellis, W.J.5    Gallaher, I.S.6
  • 45
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature. 2007;450:1235-9.
    • (2007) Nature , vol.450 , pp. 1235-1239
    • Nagrath, S.1    Sequist, L.V.2    Maheswaran, S.3    Bell, D.W.4    Irimia, D.5    Ulkus, L.6
  • 46
    • 84878828739 scopus 로고    scopus 로고
    • Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: A meta-analysis
    • Groot Koerkamp B, Rahbari NN, Buchler MW, Koch M, Weitz J. Circulating tumor cells and prognosis of patients with resectable colorectal liver metastases or widespread metastatic colorectal cancer: a meta-analysis. Annals Surg Oncol. 2013;20:2156-65.
    • (2013) Annals Surg Oncol , vol.20 , pp. 2156-2165
    • Groot Koerkamp, B.1    Rahbari, N.N.2    Buchler, M.W.3    Koch, M.4    Weitz, J.5
  • 47
    • 84873023773 scopus 로고    scopus 로고
    • Meta-analysis of circulating tumor cells as a prognostic marker in lung cancer
    • Ma X-L, Xiao Z-L, Liu L, Liu X-X, Nie W, Li P, et al. Meta-analysis of circulating tumor cells as a prognostic marker in lung cancer. Asian Pac J Cancer Prev. 2012;13:1137-44.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 1137-1144
    • Ma, X.-L.1    Xiao, Z.-L.2    Liu, L.3    Liu, X.-X.4    Nie, W.5    Li, P.6
  • 48
    • 84904725512 scopus 로고    scopus 로고
    • Assessing the clinical impact of prognostic factors: When is "statistically significant" clinically useful? Prognostic variables in node-negative and node-positive breast cancer
    • Kluwer Academic Publishers, Netherlands
    • Hayes DF, Trock B, Harris AL. Assessing the clinical impact of prognostic factors: When is "statistically significant" clinically useful? Prognostic variables in node-negative and node-positive breast cancer, Breast Cancer Res Tr. Kluwer Academic Publishers, Netherlands, 1998, 395-409.
    • (1998) Breast Cancer Res Tr , pp. 395-409
    • Hayes, D.F.1    Trock, B.2    Harris, A.L.3
  • 49
    • 42649100970 scopus 로고    scopus 로고
    • Detection, clinical relevance and specific biological properties of disseminating tumour cells
    • DOI 10.1038/nrc2375, PII NRC2375
    • Pantel K, Brakenhoff RH, Brandt B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat Rev Cancer. 2008;8:329-40. (Pubitemid 351596394)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.5 , pp. 329-340
    • Pantel, K.1    Brakenhoff, R.H.2    Brandt, B.3
  • 50
    • 84877816994 scopus 로고    scopus 로고
    • Tumor cell dissemination: Emerging biological insights from animal models and cancer patients
    • Kang Y, Pantel K. Tumor cell dissemination: emerging biological insights from animal models and cancer patients. Cancer cell. 2013;23:573-81.
    • (2013) Cancer Cell , vol.23 , pp. 573-581
    • Kang, Y.1    Pantel, K.2
  • 51
    • 84873811988 scopus 로고    scopus 로고
    • Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
    • Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, et al. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 2013;339:580-4.
    • (2013) Science , vol.339 , pp. 580-584
    • Yu, M.1    Bardia, A.2    Wittner, B.S.3    Stott, S.L.4    Smas, M.E.5    Ting, D.T.6
  • 52
    • 84856862054 scopus 로고    scopus 로고
    • Clinical significance andmolecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer
    • Hou J-M, Krebs MG, Lancashire L, Sloane R, Backen A, Swain RK, et al. Clinical significance andmolecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer. J Clin Oncol. 2012;30:525-32.
    • (2012) J Clin Oncol , vol.30 , pp. 525-532
    • Hou, J.-M.1    Krebs, M.G.2    Lancashire, L.3    Sloane, R.4    Backen, A.5    Swain, R.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.