Pyocyanin stimulates quorum sensing-mediated tolerance to oxidative stress and increases persister cell populations in Acinetobacter baumannii

Infection and Immunity

Volumn 82, Issue 8, 2014, Pages 3417-3425

  Bhargava, Nidhi ^a   Sharma, Prince ^a   Capalash, Neena ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BACTERIAL ENZYME; CARBENICILLIN; CATALASE; N (3 OXODODECANOYL)HOMOSERINE LACTONE; PYOCYANINE; REACTIVE OXYGEN METABOLITE; SALICYLIC ACID; SUPEROXIDE DISMUTASE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BIOFILM; CELL POPULATION; CONTROLLED STUDY; ENZYME SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MIXED CELL CULTURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING;

ACINETOBACTER BAUMANNII; ANTIOXIDANTS; BIOFILMS; CATALASE; MICROBIAL INTERACTIONS; OXIDATIVE STRESS; PSEUDOMONAS AERUGINOSA; PYOCYANINE; QUORUM SENSING; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84904742417     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01600-14     Document Type: Article

References (33)

1. Barth VC, Jr, Rodrigues BA, Bonatto GD, Gallo SW, Pagnussatti VE, Ferreira CAS, Oliveira DS. 2013. Heterogeneous persister cells formation in Acinetobacter baumannii. PLoS One 8:e84361. http://dx.doi.org/10 .1371/journal.pone.0084361.
2. Fiester SE, Actis LA. 2013. Stress responses in the opportunistic pathogen Acinetobacter baumannii. Future Microbiol. 8:353-365. http://dx.doi.org /10.2217/fmb.12.150.
3. Dent LL, Marshall DR, Pratap S, Hulette RB. 2010. Multidrug resistant Acinetobacter baumannii: a descriptive study in a city hospital. BMC Infect. Dis. 10:196-202. http://dx.doi.org/10.1186/1471-2334-10-196.
4. Riedel K, Hentzer M, Geisenberger O, Huber B, Steidle A, Wu H, Hoiby N, Givskov M, Molin S, Eberl L. 2001. N-acylhomoserinelactone- mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms. Microbiology 147:3249-3262.
5. Wagner VE, Iglewski BH. 2008. P. aeruginosa biofilms in CF infections. Clin. Rev. Allergy Immunol. 35:124-134. http://dx.doi.org/10.1007 /s12016-008-8079-9.
6. Rogers GB, Carroll MP, Hoffman LR, Walker AW, Fine DA, Bruce KD. 2010. Comparing the microbiota of the cystic fibrosis lung and human gut. Gut Microbes 1:85-93. http://dx.doi.org/10.4161/gmic.1.2.11350.
7. Hassett DJ, Charniga L, Bean K, Ohman DE, Cohen MS. 1992. Response of Pseudomonas aeruginosa to pyocyanin: mechanisms of resistance, antioxidant defences, and demonstration of a manganesecofactored superoxide dismutase. Infect. Immun. 60:328-336.
8. Tomlin KL, Coll OP, Ceri H. 2001. Interspecies biofilms of Pseudomonas aeruginosa and Burkholderia cepacia. Can. J. Microbiol. 47:949-954.
9. Stewart PS, Camper AK, Handran SD, Huang CT, Warnecke M. 1997. Spatial distribution and co-existence of Klebsiella pneumonia and Pseudomonas aeruginosa in biofilms. Microb. Ecol. 33:2-10. http://dx.doi.org /10.1007/s002489900002.
10. Bhargava N, Sharma P, Capalash N. 2012. N-acyl homoserine lactone mediated interspecies interactions between A. baumannii and P. aeruginosa. Biofouling 28:813-822. http://dx.doi.org/10.1080/08927014.2012 .714372.
11. Hobley L, King JR, Sockett E. 2006. Bdellovibrio predation in the presence of decoys: three-way bacterial interactions revealed by mathematical and experimental analyses. Appl. Environ. Microbiol. 72:6757-6765. http://dx.doi.org/10.1128/AEM.00844-06.
12. Sies H. 1997. Oxidative stress: oxidants and antioxidants. Exp. Physiol. 82:291-295.
13. Hassett DJ, Ma J-F, Elkins JG, McDermott TR, Ochsner UA, West SEA, Huang C-T, Fredericks J, Burnett S, Stewart PS, McFeters G, Passador L, Iglewski BH. 1999. Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes mediates biofilm susceptibility to hydrogen peroxide. Mol. Microbiol. 34:1082-1093. http://dx.doi.org/10.1046/j.1365-2958.1999.01672.x.
14. Niu C, Clemmer KM, Bonomo RA, Rather PN. 2008. Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii. J. Bacteriol. 190:3386-3392. http://dx.doi.org/10.1128/JB.01929-07.
15. Wang X, Wood TK. 2011. Toxin-antitoxin systems influence biofilm and persister cell formation and the general stress response. Appl. Environ. Microbiol. 77:5577-5583. http://dx.doi.org/10.1128/AEM.05068-11.
16. Caldwell CC, Chen Y, Goetzmann HS, Hao Y, Borchers MT, Hassett DJ, Young LR, Mavrodi D, Thomashow L, Lau GW. 2009. Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis. Am. J. Pathol. 175:2473-2488. http://dx.doi.org/10.2353/ajpath.2009 .090166.
17. Iglewski BH, Pesci EC, Pearson JP, Seed PC. 1997. Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J. Bacteriol. 179:3127- 3132.
18. Haagensen JAS, Klausen M, Ernst RK, Miller SI, Folkesson A, Tolker- Nielsen T, Molin S. 2007. Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms. J. Bacteriol. 189:28-37. http://dx.doi.org/10.1128/JB.00720-06.
19. Kraigsley AM, Finkel SE. 2009. Adaptive evolution in single species bacterial biofilms. FEMS Microbiol. Lett. 293:135-140. http://dx.doi.org/10 .1111/j.1574-6968.2009.01526.x.
20. Sambrook J, Russell DW. 2001. Molecular cloning: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
21. Dorsey CW, Tomaras AP, Actis LA. 2002. Genetic and phenotypic analysis of Acinetobacter baumannii insertion derivatives generated with a transposome system. Appl. Environ. Microbiol. 68:6353-6360. http://dx .doi.org/10.1128/AEM.68.12.6353-6360.2002.
22. Stewart PS, Camper AK, Handran SD, Huang C-T, Warnecke M. 1997. Spatial distribution and coexistence of Klebsiella pneumonia and Pseudomonas aeruginosa in biofilms. Microb. Ecol. 33:2-10. http://dx.doi.org /10.1007/s002489900002.
23. Essar DW, Eberly L, Hadero A, Crawford IP. 1990. Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications. J. Bacteriol. 172:884-900.
24. Kim S, Kim MJ, Kang HY, Seol SY, Cho DT, Kim J. 2010. A simple colorimetric method for testing antimicrobial susceptibility of biofilmed bacteria. J. Microbiol. 48:709-711. http://dx.doi.org/10.1007/s12275-010 -0299-z.
25. Hillegass JM, Shukla A, MacPherson MB, Lathrop SA, Alexeeva V, Perkins T, Vliet AVA, Vacek PM, Gunter ME, Brooke T. 2010. Mechanisms of oxidative stress and alterations in gene expression by Libby six-mix in human mesothelial cells. Part. Fibre Toxicol. 7:26-40. http://dx .doi.org/10.1186/1743-8977-7-26.
26. Desjardins P, Hansen JB, Allen M. 2009. Microvolume protein concentration determination using the NanoDrop 2000c spectrophotometer. J. Vis. Exp. 2009(33):e1610. http://www.jove.com/details.php?id1610. http://dx.doi.org/10.3791/1610.
27. Kakkar P, Das B, Viswanathan PN. 1984. A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem. Biophys. 21:130-132.
28. Andrews JM. 2001. Determination of minimum inhibitory concentrations. J. Antimicrob. Chemother. 48:5-16. http://dx.doi.org/10.1093/jac /48.suppl_1.5.
29. Leung V, Levesque CM. 2012. A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance. J. Bacteriol. 194:2265-2274. http://dx.doi.org/10 .1128/JB.06707-11.
30. Moker N, Dean CR, Tao J. 2010. Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum sensing signaling molecules. J. Bacteriol. 192:1946-1955. http://dx.doi .org/10.1128/JB.01231-09.
31. Price-Whelan A, Dietrich LE, Newman DK. 2006. Rethinking 'secondary' metabolism: physiological roles for phenazine antibiotics. Nat. Chem. Biol. 2:71-78. http://dx.doi.org/10.1038/nchembio764.
32. Di Capua C, Bortolotti A, Farias ME, Cortez N. 2011. UV-resistant Acinetobacter sp. isolates from Andean wetlands display high catalase activity. FEMS Microbiol. Lett. 317:181-189. http://dx.doi.org/10.1111/j .1574-6968.2011.02231.x.
33. Rasmussen TB, Givskov M. 2006. Quorum sensing inhibitors; a bargain of effects. Microbiol. 152:895-904. http://dx.doi.org/10.1099/mic.0.28601-0.