Heterogeneous persister cells formation in Acinetobacter baumannii

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Barth Jr , Valdir Cristóvão ^a   Rodrigues, Belisa Av́ila ^a   Bonatto, Grasiela Daiane ^a   Gallo, Stephanie Wagner ^a   Pagnussatti, Vany Elisa ^a   Ferreira, Carlos Alexandre Sanchez ^a   De Oliveira, Sílvia Dias ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMYXIN B; TOBRAMYCIN;

ACINETOBACTER BAUMANNII; ARTICLE; BACTERIAL CELL; BACTERIAL STRAIN; BACTERIUM ISOLATE; COLONY FORMATION; COLONY FORMING UNIT; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PERSISTER CELL; PHENOTYPE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; COLONY COUNT, MICROBIAL; DRUG RESISTANCE, BACTERIAL; MICROBIAL VIABILITY; PHENOTYPE; POLYMYXIN B; SPECIES SPECIFICITY; TOBRAMYCIN;

EID: 84896727096     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084361     Document Type: Article

References (27)

1. Stewart B, Rozen DE (2012) Genetic variation for antibiotic persistence in Escherichia coli. Evolution 66: 933-939.
2. Möker N, Dean CR, Tao J (2010) Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum-sensing signaling molecules. J Bacteriol 192: 1946-1955.
3. Bigger JW (1944) Treatment of staphylococcal infections with penicillin by intermittent sterilisation. The Lancet 244: 497-500.
4. Grant SS, Kaufmann BB, Chand NS, Haseley N, Hung DT (2012) Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. Proc Natl Acad Sci U S A 109: 12147-12152.
5. Lewis K (2007) Persister cells, dormancy and infectious disease. Nat Rev Microbiol 5: 48-56.
6. Fauvart M, De Groote VN, Michiels J (2011) Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies. J Med Microbiol 60: 699-709.
7. Tashiro Y, Kawata K, Taniuchi A, Kakinuma K, May T, et al. (2012) RelE-mediated dormancy is enhanced at high cell density in Escherichia coli. J Bacteriol 194: 1169-1176.
8. Maisonneuve E, Shakespeare LJ, Jørgensen MG, Gerdes K (2011) Bacterial persistence by RNA endonucleases. Proc Natl Acad Sci U S A 108: 13206-13211.
9. Orman M, Brynildsen MP (2013) Dormancy is not necessary or sufficient for bacterial persistence. Antimicrob Agents Chemother 57: 3230-3239.
10. Wakamoto Y, Dhar N, Chait R, Schneider K, Signorino-Gelo F, et al. (2013) Dynamic persistence of antibiotic-stressed mycobacteria. Science 339: 91-95.
11. Wu Y, Vulić M, Keren I, Lewis K (2012) Role of oxidative stress in persister tolerance. Antimicrob Agents Chemother 56: 4922-4926.
12. Bernier SP, Lebeaux D, DeFrancesco AS, Valomon A, Soubigou G, et al. (2013) Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin. PLoS Genet 9: e1003144.
13. Keren I, Shah D, Spoering A, Kaldalu N, Lewis K (2004) Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J Bacteriol 186: 8172-8180. (Pubitemid 39603206)
14. Fasani RA, Savageau MA (2013) Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype. Proc Natl Acad Sci U S A 110: E2528-E2537.
15. Correia FF, D'Onofrio A, Rejtar T, Li L, Karger BL, et al. (2006) Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli. J Bacteriol 188: 8360-8367. (Pubitemid 44894035)
16. Clinical and Laboratory Standards Institute (2012) Performance standards for antimicrobial disk susceptibility tests; Approved Standard - Eleventh Edition. CLSI document M02-A11.
17. Clinical and Laboratory Standards Institute (2012) Performance standards for antimicrobial susceptibility testing; Twenty-Second Informational Supplement. CLSI Document M100-S22 32.
18. Hofsteenge N, Van Nimwegen E, Silander OK (2013) Quantitative analysis of persister fractions suggests different mechanisms of formation among environmental isolates of E. coli. BMC Microbiol 13: 25.
19. Jurenaite M, Markuckas A, Suziedeliene E (2013) Identification and characterization of type II toxin-antitoxin systems in the opportunistic pathogen Acinetobacter baumannii. J Bacteriol 195: 3165-3172.
20. Dörr T, Vulić M, Lewis K (2010) Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli. PLoS Biol 8: e1000317.
21. Knudsen GM, Ng Y, Gram L (2013) Survival of Bactericidal Antibiotic Treatment by a Persister Subpopulation of Listeria monocytogenes. Appl Environ Microbiol 79: 7390-7397.
22. Moffatt JH, Harper M, Harrison P, Hale JDF, Vinogradov E, et al. (2010) Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production. Antimicrob Agents Chemother 54: 4971-4977.
23. Sampson TR, Liu X, Schroeder MR, Kraft CS, Burd EM, et al. (2012) Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway. Antimicrob Agents Chemother 56: 5642-5649.
24. Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ (2007) A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130: 797-810. (Pubitemid 47332566)
25. Keren I, Wu Y, Inocencio J, Mulcahy LR, Lewis K (2013) Killing by bactericidal antibiotics does not depend on reactive oxygen species. Science 339: 1213-1216.
26. Renggli S, Keck W, Jenal U, Ritz D (2013) The role of auto-fluorescence in flow-cytometric analysis of Escherichia coli treated with bactericidal antibiotics. J Bacteriol 195: 4067-4073.
27. Liu Y, Imlay JA (2013) Cell death from antibiotics without the involvement of reactive oxygen species. Science 339: 1210-1213.