Association between serotonin Cumulative Genetic Score and the Behavioral Approach System (BAS): Moderation by early life environment

Personality and Individual Differences

Volumn 70, Issue , 2014, Pages 140-144

  Pearson, Rahel ^a   McGeary, John E ^b,c   Beevers, Christopher G ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b PROVIDENCE VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Behavioral approach system; Environmental adversity; GxE; Reward sensitivity; Serotonin function

Indexed keywords

EID: 84904738573     PISSN: 01918869     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.paid.2014.06.041     Document Type: Article

References (39)

1. Ahn K.C., Pazderka-Robinson H., Clements R., Ashcroft R., Ali T., Morse C., et al. Differential effects of intra-midbrain raphe and systemic 8-OH-DPAT on VTA self-stimulation thresholds in rats. Psychopharmacology 2005, 178:381-388.
2. Alloy L.B., Abramson L.Y. The role of the behavioral approach system (BAS) in bipolar spectrum disorders. Current Directions in Psychological Science 2010, 19:189-194.
3. Andre K., Kampman O., Setälä-Soikkeli E., Vikkii M., Poutanen O., Nuolivirta T., Illi A. Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression. Journal of Neural Transmission 2010, 117:1431-1434.
4. Bah J., Lindström M., Westberg L., Mannerås L., Ryding E., Henningsson S., Eriksson E. Serotonin transporter gene polymorphisms: Effect on serotonin transporter availability in the brain of suicide attempters. Psychiatry Research Neuroimaging 2008, 162:221-229.
5. Bernstein D.P., Stein J.A., Newcomb M.D., Walker E., Pogge D., Ahluvalia T., Zule W. Development and validation of a brief screening version of the Childhood Trauma Questionnaire. Child Abuse and Neglect 2003, 27:169-190.
6. Carkaci-Salli N., Salli U., Kuntz-Melcavage K.L., Pennock M.M., Ozgen H., Tekin I., et al. TPH2 in the ventral tegmental area of the male rat brain. Brain Research Bulletin 2011, 84:376-380.
7. Carver C.S., Johnson S.L., Joormann J. Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: What depression has in common with impulsive aggression. Psychological Bulletin 2008, 134:912-943.
8. Carver C.S., Miller C.J. Relations of serotonin function to personality: Current views and a key methodological issue. Psychiatry Research 2006, 144:1-15.
9. Carver C.S., White T.L. Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: The BIS/BAS Scales. Journal of Personality and Social Psychology 1994, 67:319-333.
10. Cloninger C.R. A unified biosocial theory of personality and its role in the development of anxiety states. Psychiatric Developments 1986, 4:167-226.
11. Czoty P.W., McCabe C., Nader M.A. Effects of the 5-HT1A agonist (±)-8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on cocaine choice in cynomolgus monkeys. Behavioral Pharmacology 2005, 16. 197-91.
12. Dillon D.G., Holmes A.J., Birk J.L., Brooks N., Lyons-Ruth K., Pizzagalli D.A. Childhood adversity is associated with left basal ganglia dysfunction during reward anticipation in adulthood. Biological Psychiatry 2009, 66:206-213.
13. Disner S.G., McGeary J.E., Wells T.T., Ellis A.J., Beevers C.G. 5-HTTLPR, HTR1A, HTR2A cumulative genetic score interacts with mood reactivity to predict mood congruent gaze bias. Cognitive Affective Behavioral Neuroscience 2014, Advance online publication.
14. Eysenck H.J. Dimensions of personality 1947, Paul, Trench, Truber & Co., London. 1st ed.
15. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured clinical interview for DSM-IV-TR Axis I disorders, research version, patient edition (SCID-I/P) 2002, Biometrics Research, New York State Psychiatric Institute, New York.
16. Gibb B.E., Beevers C.G., McGeary J.E. Toward an integration of cognitive and genetic models of risk for depression. Cognition and Emotion 2012, 27:193-216.
17. Guyer A.E., Kaufman J., Hodgdon H.B., Masten C.L., Jazbec S., Pine D.S., et al. Behavioral alterations in reward system function: The role of childhood maltreatment and psychopathology. Journal of the American Academy of Child and Adolescent Psychiatry 2006, 45:1059-1067.
18. Hahn T., Heinzel S., Dresler T., Plitcha M.M., Tenner T.J., Markulin F., et al. Association between reward-related activation in the ventral striatum and trait reward sensitivity is moderated by dopamine transporter genotype. Human Brain Mapping 2011, 32:1557-1565.
19. Holmes A.J., Lee P.H., Hollinshead M.O., Bakst L., Roffman J.L., Smoller J.W., et al. Individual differences in amygdala-medial prefrontal anatomy link negative affect, impaired social functioning, and polygenic depression risk. Journal of Neuroscience 2012, 32:18087-18100.
20. Insel T., Cuthbert B., Garvey M., Heinssen R., Pine D.S., Quinn K., et al. Research Domain Criteria (RDoC): Towards a new classification framework for research on mental disorders. American Journal of Psychiatry 2010, 167:748-751.
21. Johnson S.L., Turner R.J., Iwata N. BIS/BAS levels and psychiatric disorder: An epidemiological study. Journal of Psychopathology and Behavioral Assessment 2003, 25:25-36.
22. Juckel G., Schlagenhauf F., Koslowski M., Wustenberg T., Villringer A., Knutson B., et al. Dysfunction of ventral striatal reward prediction in schizophrenia. Neuroimage 2005, 29:409-416.
23. Kasch K.L., Rottenberg J., Arrow B.A., Gotlib I.H. Behavioral activation and inhibition systems and the severity and course of depression. Journal of Abnormal Psychology 2002, 111:589-597.
24. Kishi T., Tsunaka T., Ikeda M., Kawashima K., Kinoshita Y., Okumura T., et al. Serotonin 1A receptor gene and major depressive disorder: An association study and meta-analysis. Journal of Human Genetics 2009, 54:629-633.
25. Liechti M.E., Saur M.R., Gamma A., Hell D., Vollenweider F.X. Psychological and physiological effects of MDMA ("Ecstasy") after pretreatment with the 5-HT(2) antagonist ketanserin in healthy humans. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2000, 23(4):396-404.
26. Matthews K., Robbins T.W. Early experience as a determinant of adult behavioural responses to reward: The effects of repeated maternal separation in the rat. Neuroscience and Biobehavioral Reviews 2003, 27:45-55.
27. Mehta M.A., Gore-Langton E., Golembo N., Colbert E., Williams S.C.R., Sonuga-Barke E. Journal of Cognitive Neuroscience 2010, 22:2316-2325.
28. Nugent A.C., Brain E.E., Carlson P.J., Neurmeister A., Bonne O., Carson R., et al. Reduced post-synaptic serotonin type 1A reception binding in bipolar depression. European Neuropsychopharmacology 2013, 23:822-829.
29. Owens M.J., Nemeroff C.B. Role of serotonin in the pathophysiology of depression: Focus on the serotonin transporter. Clinical Chemistry 1994, 40:288-295.
30. Rogers R.D., Tunbridge E.M., Bhagwagar Z., Drevets W.C., Sahakian B.J., Carter C.S. Tryptophan depletion alters the decision-making of healthy volunteers through altered processing of reward cues. Neuropsychopharmacology 2003, 28:153-162.
31. Roiser J.P., Blackwell A.D., Cools R., Clark L., Rubinsztein D.C., Robbins T.W., et al. Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion. Neuropsychopharmacology 2006, 31:2264-2272.
32. Spanagel R., Weiss F. The dopamine hypothesis of reward: Past and current status. Trends in Neuroscience 1999, 22:521-527.
33. StataCorp. Stata Statistical Software: Release 12 2013, StataCorp LP, College Station, TX.
34. Watson K.K., Ghodasra J.H., Platt M.L. Serotonin transporter genotype modulates social reward and punishment in rhesus macaques. PLoS ONE 2009, 4:e4156.
35. Zangen A., Nakash R., Overstreet D., Yadid G. Association between depressive behavior and absence of serotonin-dopamine interaction in the nucleus accumbens. Psychopharmacology 2001, 155:434-439.
36. Zhang X., Beaulieu J., Sotnikova T.D., Gainetdinov R.R., Caron M.G. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science 2004, 305:217.
37. Zhang U., Zhang C., Yuan G., Yao J., Zaohuo, Cheng Z., et al. Effect of tryptophan hydroxylase-2 rs 7305115 SNP on suicide attempt risk in major depression. Behavioral and Brain Functions 2011, 6:49.
38. Zhong S., Israel S., Xue H., Sham P.C., Ebstein R.P., Chew S. A neurochemical approach to valuation sensitivity over gains and losses. Proceedings of the Royal Society of Biological Sciences 2009, 276:4181-4188.
39. Zill P., Baghai T.C., Zwanzger P., Schule C., Eser D., Tupprecht R., et al. SNP and haplotype analysis of a novel tryptophan hydroxylase isoform TPH2_gnee provide evidence for association with major depression. Molecular Psychiatry 2004, 9:1030-1036.