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Volumn 40, Issue 8, 2014, Pages 951-

Systemic treatments for brain metastases from breast cancer, non-small cell lung cancer, melanoma and renal cell carcinoma: An overview of the literature

Author keywords

Brain metastases; Breast cancer; Lung cancer; Melanoma; Renal cell carcinoma

Indexed keywords

ANGIOGENESIS INHIBITOR; BEVACIZUMAB; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR;

EID: 84904736573     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2014.05.007     Document Type: Review
Times cited : (46)

References (78)
  • 1
    • 4344694453 scopus 로고    scopus 로고
    • Incidence proportions of brain metastases in patients diagnosed (1973-2001) in the Metropolitan Detroit Cancer Surveillance System
    • Barnholtz-Sloan J.S., Sloan A.E., Davis F.G., Vigneau F.D., Lai P., Sawaya R.E. Incidence proportions of brain metastases in patients diagnosed (1973-2001) in the Metropolitan Detroit Cancer Surveillance System. J Clin Oncol 2004, 22:2865-2872.
    • (2004) J Clin Oncol , vol.22 , pp. 2865-2872
    • Barnholtz-Sloan, J.S.1    Sloan, A.E.2    Davis, F.G.3    Vigneau, F.D.4    Lai, P.5    Sawaya, R.E.6
  • 3
    • 55549128225 scopus 로고    scopus 로고
    • A phase 2 trial of whole-brain radiotherapy combined with intravenous chemotherapy in patients with brain metastases from breast cancer
    • Cassier P.A., Ray-Coquard I., Sunyach M.P., Lancry L., Guastalla J.P., Ferlay C., et al. A phase 2 trial of whole-brain radiotherapy combined with intravenous chemotherapy in patients with brain metastases from breast cancer. Cancer 2008, 113:2532-2538.
    • (2008) Cancer , vol.113 , pp. 2532-2538
    • Cassier, P.A.1    Ray-Coquard, I.2    Sunyach, M.P.3    Lancry, L.4    Guastalla, J.P.5    Ferlay, C.6
  • 4
    • 0033120802 scopus 로고    scopus 로고
    • Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma: a prospective study
    • Franciosi V., Cocconi G., Michiara M., Di Costanzo F., Fosser V., Tonato M., et al. Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma: a prospective study. Cancer 1999, 85:1599-1605.
    • (1999) Cancer , vol.85 , pp. 1599-1605
    • Franciosi, V.1    Cocconi, G.2    Michiara, M.3    Di Costanzo, F.4    Fosser, V.5    Tonato, M.6
  • 5
    • 77949638554 scopus 로고    scopus 로고
    • Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study
    • Siena S., Crino L., Danova M., Del Prete S., Cascinu S., Salvagni S., et al. Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. Ann Oncol 2010, 21:655-661.
    • (2010) Ann Oncol , vol.21 , pp. 655-661
    • Siena, S.1    Crino, L.2    Danova, M.3    Del Prete, S.4    Cascinu, S.5    Salvagni, S.6
  • 6
    • 33749026073 scopus 로고    scopus 로고
    • Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma
    • Rivera E., Meyers C., Groves M., Valero V., Francis D., Arun B., et al. Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma. Cancer 2006, 107:1348-1354.
    • (2006) Cancer , vol.107 , pp. 1348-1354
    • Rivera, E.1    Meyers, C.2    Groves, M.3    Valero, V.4    Francis, D.5    Arun, B.6
  • 7
    • 82255177135 scopus 로고    scopus 로고
    • A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases
    • Freedman R.A., Bullitt E., Sun L., Gelman R., Harris G., Ligibel J.A., et al. A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases. Clin Breast Cancer 2011, 11:376-383.
    • (2011) Clin Breast Cancer , vol.11 , pp. 376-383
    • Freedman, R.A.1    Bullitt, E.2    Sun, L.3    Gelman, R.4    Harris, G.5    Ligibel, J.A.6
  • 8
    • 79960429096 scopus 로고    scopus 로고
    • Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER
    • Brufsky A.M., Mayer M., Rugo H.S., Kaufman P.A., Tan-Chiu E., Tripathy D., et al. Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER. Clin Cancer Res 2011, 17:4834-4843.
    • (2011) Clin Cancer Res , vol.17 , pp. 4834-4843
    • Brufsky, A.M.1    Mayer, M.2    Rugo, H.S.3    Kaufman, P.A.4    Tan-Chiu, E.5    Tripathy, D.6
  • 9
    • 80052198656 scopus 로고    scopus 로고
    • Neoplastic meningitis from solid tumors: new diagnostic and therapeutic approaches
    • Lombardi G., Zustovich F., Farina P., Della Puppa A., Manara R., Cecchin D., et al. Neoplastic meningitis from solid tumors: new diagnostic and therapeutic approaches. Oncologist 2011, 16:1175-1188.
    • (2011) Oncologist , vol.16 , pp. 1175-1188
    • Lombardi, G.1    Zustovich, F.2    Farina, P.3    Della Puppa, A.4    Manara, R.5    Cecchin, D.6
  • 10
    • 63949084960 scopus 로고    scopus 로고
    • Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab
    • Colozza M., Minenza E., Gori S., Fenocchio D., Paolucci C., Aristei C., et al. Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab. Cancer Chemother Pharmacol 2009, 63:1157-1159.
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 1157-1159
    • Colozza, M.1    Minenza, E.2    Gori, S.3    Fenocchio, D.4    Paolucci, C.5    Aristei, C.6
  • 11
    • 42949112556 scopus 로고    scopus 로고
    • Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer
    • Lin N.U., Carey L.A., Liu M.C., Younger J., Come S.E., Ewend M., et al. Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 2008, 26:1993-1999.
    • (2008) J Clin Oncol , vol.26 , pp. 1993-1999
    • Lin, N.U.1    Carey, L.A.2    Liu, M.C.3    Younger, J.4    Come, S.E.5    Ewend, M.6
  • 12
    • 63149110733 scopus 로고    scopus 로고
    • Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer
    • Lin N.U., Dieras V., Paul D., Lossignol D., Christodoulou C., Stemmler H.J., et al. Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer. Clin Cancer Res 2009, 15:1452-1459.
    • (2009) Clin Cancer Res , vol.15 , pp. 1452-1459
    • Lin, N.U.1    Dieras, V.2    Paul, D.3    Lossignol, D.4    Christodoulou, C.5    Stemmler, H.J.6
  • 13
    • 82955163167 scopus 로고    scopus 로고
    • Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases
    • Lin N.U., Eierman W., Greil R., Campone M., Kaufman B., Steplewski K., et al. Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases. J Neurooncol 2011, 105:613-620.
    • (2011) J Neurooncol , vol.105 , pp. 613-620
    • Lin, N.U.1    Eierman, W.2    Greil, R.3    Campone, M.4    Kaufman, B.5    Steplewski, K.6
  • 14
    • 84871722407 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study
    • Bachelot T., Romieu G., Campone M., Dieras V., Cropet C., Dalenc F., et al. Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study. Lancet Oncol 2013, 14:64-71.
    • (2013) Lancet Oncol , vol.14 , pp. 64-71
    • Bachelot, T.1    Romieu, G.2    Campone, M.3    Dieras, V.4    Cropet, C.5    Dalenc, F.6
  • 15
    • 84890439476 scopus 로고    scopus 로고
    • A phase I study of lapatinib with whole brain radiotherapy in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer brain metastases
    • Lin N.U., Freedman R.A., Ramakrishna N., Younger J., Storniolo A.M., Bellon J.R., et al. A phase I study of lapatinib with whole brain radiotherapy in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer brain metastases. Breast Cancer Res Treat 2013, 142:405-414.
    • (2013) Breast Cancer Res Treat , vol.142 , pp. 405-414
    • Lin, N.U.1    Freedman, R.A.2    Ramakrishna, N.3    Younger, J.4    Storniolo, A.M.5    Bellon, J.R.6
  • 16
    • 84866916849 scopus 로고    scopus 로고
    • Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival
    • Yap Y.S., Cornelio G.H., Devi B.C., Khorprasert C., Kim S.B., Kim T.Y., et al. Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival. Br J Cancer 2012, 107:1075-1082.
    • (2012) Br J Cancer , vol.107 , pp. 1075-1082
    • Yap, Y.S.1    Cornelio, G.H.2    Devi, B.C.3    Khorprasert, C.4    Kim, S.B.5    Kim, T.Y.6
  • 17
    • 84861735490 scopus 로고    scopus 로고
    • Retreatment with trastuzumab-based therapy after disease progression following lapatinib in HER2-positive metastatic breast cancer
    • Gori S., Montemurro F., Spazzapan S., Metro G., Foglietta J., Bisagni G., et al. Retreatment with trastuzumab-based therapy after disease progression following lapatinib in HER2-positive metastatic breast cancer. Ann Oncol 2012, 23:1436-1441.
    • (2012) Ann Oncol , vol.23 , pp. 1436-1441
    • Gori, S.1    Montemurro, F.2    Spazzapan, S.3    Metro, G.4    Foglietta, J.5    Bisagni, G.6
  • 18
    • 0031904419 scopus 로고    scopus 로고
    • Is it time to reevaluate our approach to the treatment of brain metastases in patients with non-small cell lung cancer?
    • Kelly K., Bunn P.A. Is it time to reevaluate our approach to the treatment of brain metastases in patients with non-small cell lung cancer?. Lung Cancer 1998, 20:85-91.
    • (1998) Lung Cancer , vol.20 , pp. 85-91
    • Kelly, K.1    Bunn, P.A.2
  • 19
    • 84880464060 scopus 로고    scopus 로고
    • Pemetrexed and cisplatin combination with concurrent whole brain radiotherapy in patients with brain metastases of lung adenocarcinoma: a single-arm phase II clinical trial
    • Dinglin X.X., Huang Y., Liu H., Zeng Y.D., Hou X., Chen L.K. Pemetrexed and cisplatin combination with concurrent whole brain radiotherapy in patients with brain metastases of lung adenocarcinoma: a single-arm phase II clinical trial. J Neurooncol 2013, 112:461-466.
    • (2013) J Neurooncol , vol.112 , pp. 461-466
    • Dinglin, X.X.1    Huang, Y.2    Liu, H.3    Zeng, Y.D.4    Hou, X.5    Chen, L.K.6
  • 20
    • 18744393078 scopus 로고    scopus 로고
    • Front-line paclitaxel/cisplatin-based chemotherapy in brain metastases from non-small-cell lung cancer
    • Cortes J., Rodriguez J., Aramendia J.M., Salgado E., Gurpide A., Garcia-Foncillas J., et al. Front-line paclitaxel/cisplatin-based chemotherapy in brain metastases from non-small-cell lung cancer. Oncology 2003, 64:28-35.
    • (2003) Oncology , vol.64 , pp. 28-35
    • Cortes, J.1    Rodriguez, J.2    Aramendia, J.M.3    Salgado, E.4    Gurpide, A.5    Garcia-Foncillas, J.6
  • 21
    • 0025028531 scopus 로고
    • Chemotherapy with high-dose cisplatin in brain metastasis of lung cancers
    • Kleisbauer J.P., Guerin J.C., Arnaud A., Poirier R., Vesco D. Chemotherapy with high-dose cisplatin in brain metastasis of lung cancers. Bull Cancer 1990, 77:661-665.
    • (1990) Bull Cancer , vol.77 , pp. 661-665
    • Kleisbauer, J.P.1    Guerin, J.C.2    Arnaud, A.3    Poirier, R.4    Vesco, D.5
  • 22
    • 0033214778 scopus 로고    scopus 로고
    • Concomitant brain radiotherapy and vinorelbine-ifosfamide-cisplatin chemotherapy in brain metastases of non-small cell lung cancer
    • Quantin X., Khial F., Reme-Saumon M., Michel F.B., Pujol J.L. Concomitant brain radiotherapy and vinorelbine-ifosfamide-cisplatin chemotherapy in brain metastases of non-small cell lung cancer. Lung Cancer 1999, 26:35-39.
    • (1999) Lung Cancer , vol.26 , pp. 35-39
    • Quantin, X.1    Khial, F.2    Reme-Saumon, M.3    Michel, F.B.4    Pujol, J.L.5
  • 23
    • 58749092817 scopus 로고    scopus 로고
    • A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer
    • Neuhaus T., Ko Y., Muller R.P., Grabenbauer G.G., Hedde J.P., Schueller H., et al. A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer. Br J Cancer 2009, 100:291-297.
    • (2009) Br J Cancer , vol.100 , pp. 291-297
    • Neuhaus, T.1    Ko, Y.2    Muller, R.P.3    Grabenbauer, G.G.4    Hedde, J.P.5    Schueller, H.6
  • 24
    • 26444591528 scopus 로고    scopus 로고
    • Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study
    • Giorgio C.G., Giuffrida D., Pappalardo A., Russo A., Santini D., Salice P., et al. Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study. Lung Cancer 2005, 50:247-254.
    • (2005) Lung Cancer , vol.50 , pp. 247-254
    • Giorgio, C.G.1    Giuffrida, D.2    Pappalardo, A.3    Russo, A.4    Santini, D.5    Salice, P.6
  • 25
    • 67849103953 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as a first-line therapy for never-smokers with adenocarcinoma of the lung having asymptomatic synchronous brain metastasis
    • Kim J.E., Lee D.H., Choi Y., Yoon D.H., Kim S.W., Suh C., et al. Epidermal growth factor receptor tyrosine kinase inhibitors as a first-line therapy for never-smokers with adenocarcinoma of the lung having asymptomatic synchronous brain metastasis. Lung Cancer 2009, 65:351-354.
    • (2009) Lung Cancer , vol.65 , pp. 351-354
    • Kim, J.E.1    Lee, D.H.2    Choi, Y.3    Yoon, D.H.4    Kim, S.W.5    Suh, C.6
  • 26
    • 10444237217 scopus 로고    scopus 로고
    • Gefitinib is active in patients with brain metastases from non-small cell lung cancer and response is related to skin toxicity
    • Chiu C.H., Tsai C.M., Chen Y.M., Chiang S.C., Liou J.L., Perng R.P. Gefitinib is active in patients with brain metastases from non-small cell lung cancer and response is related to skin toxicity. Lung Cancer 2005, 47:129-138.
    • (2005) Lung Cancer , vol.47 , pp. 129-138
    • Chiu, C.H.1    Tsai, C.M.2    Chen, Y.M.3    Chiang, S.C.4    Liou, J.L.5    Perng, R.P.6
  • 27
    • 84856235127 scopus 로고    scopus 로고
    • Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Cancer Research (SAKK 70/03)
    • Pesce G.A., Klingbiel D., Ribi K., Zouhair A., von Moos R., Schlaeppi M., et al. Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Cancer Research (SAKK 70/03). Eur J Cancer 2012, 48:377-384.
    • (2012) Eur J Cancer , vol.48 , pp. 377-384
    • Pesce, G.A.1    Klingbiel, D.2    Ribi, K.3    Zouhair, A.4    von Moos, R.5    Schlaeppi, M.6
  • 28
    • 67449122414 scopus 로고    scopus 로고
    • Treatment of brain metastasis from non-small cell lung cancer with whole brain radiotherapy and gefitinib in a Chinese population
    • Ma S., Xu Y., Deng Q., Yu X. Treatment of brain metastasis from non-small cell lung cancer with whole brain radiotherapy and gefitinib in a Chinese population. Lung Cancer 2009, 65:198-203.
    • (2009) Lung Cancer , vol.65 , pp. 198-203
    • Ma, S.1    Xu, Y.2    Deng, Q.3    Yu, X.4
  • 29
    • 84881667804 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor mutations on intracranial treatment response and survival after brain metastases in lung adenocarcinoma patients
    • Hsiao S.H., Lin H.C., Chou Y.T., Lin S.E., Kuo C.C., Yu M.C., et al. Impact of epidermal growth factor receptor mutations on intracranial treatment response and survival after brain metastases in lung adenocarcinoma patients. Lung Cancer 2013, 81:455-461.
    • (2013) Lung Cancer , vol.81 , pp. 455-461
    • Hsiao, S.H.1    Lin, H.C.2    Chou, Y.T.3    Lin, S.E.4    Kuo, C.C.5    Yu, M.C.6
  • 30
    • 84875720245 scopus 로고    scopus 로고
    • Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer
    • Welsh J.W., Komaki R., Amini A., Munsell M.F., Unger W., Allen P.K., et al. Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer. J Clin Oncol 2013, 31:895-902.
    • (2013) J Clin Oncol , vol.31 , pp. 895-902
    • Welsh, J.W.1    Komaki, R.2    Amini, A.3    Munsell, M.F.4    Unger, W.5    Allen, P.K.6
  • 31
    • 84876123594 scopus 로고    scopus 로고
    • The effectiveness of erlotinib against brain metastases in non-small cell lung cancer patients
    • Bai H., Han B. The effectiveness of erlotinib against brain metastases in non-small cell lung cancer patients. Am J Clin Oncol 2013, 36:110-115.
    • (2013) Am J Clin Oncol , vol.36 , pp. 110-115
    • Bai, H.1    Han, B.2
  • 32
    • 4143110253 scopus 로고    scopus 로고
    • Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial
    • Ceresoli G.L., Cappuzzo F., Gregorc V., Bartolini S., Crino L., Villa E. Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial. Ann Oncol 2004, 15:1042-1047.
    • (2004) Ann Oncol , vol.15 , pp. 1042-1047
    • Ceresoli, G.L.1    Cappuzzo, F.2    Gregorc, V.3    Bartolini, S.4    Crino, L.5    Villa, E.6
  • 33
    • 77951630948 scopus 로고    scopus 로고
    • Gefitinib in the treatment of advanced non-small cell lung cancer with brain metastasis
    • Wu C., Li L.Y., Wang M.Z., Zhang L., Zhang X.T., Zhong W., et al. Gefitinib in the treatment of advanced non-small cell lung cancer with brain metastasis. Zhonghua Zhong Liu Za Zhi 2007, 29:943-945.
    • (2007) Zhonghua Zhong Liu Za Zhi , vol.29 , pp. 943-945
    • Wu, C.1    Li, L.Y.2    Wang, M.Z.3    Zhang, L.4    Zhang, X.T.5    Zhong, W.6
  • 35
    • 70449725036 scopus 로고    scopus 로고
    • Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases
    • Socinski M.A., Langer C.J., Huang J.E., Kolb M.M., Compton P., Wang L., et al. Safety of bevacizumab in patients with non-small-cell lung cancer and brain metastases. J Clin Oncol 2009, 27:5255-5261.
    • (2009) J Clin Oncol , vol.27 , pp. 5255-5261
    • Socinski, M.A.1    Langer, C.J.2    Huang, J.E.3    Kolb, M.M.4    Compton, P.5    Wang, L.6
  • 36
    • 84904750980 scopus 로고    scopus 로고
    • Efficacy and safety of bevacizumab in nonsquamous non-small cell lung cancer with brain metastases
    • suppl; abstr e19134
    • Ichiki M., Yoshida T., Nakamura M., Kumano T., Hoshino T. Efficacy and safety of bevacizumab in nonsquamous non-small cell lung cancer with brain metastases. J Clin Oncol 2013, 31. suppl; abstr e19134.
    • (2013) J Clin Oncol , vol.31
    • Ichiki, M.1    Yoshida, T.2    Nakamura, M.3    Kumano, T.4    Hoshino, T.5
  • 37
    • 84885003143 scopus 로고    scopus 로고
    • Bevacizumab as front-line treatment of brain metastases from solid tumors: a case series
    • Zustovich F., Ferro A., Lombardi G., Zagonel V., Fiduccia P., Farina P. Bevacizumab as front-line treatment of brain metastases from solid tumors: a case series. Anticancer Res 2013, 33:4061-4065.
    • (2013) Anticancer Res , vol.33 , pp. 4061-4065
    • Zustovich, F.1    Ferro, A.2    Lombardi, G.3    Zagonel, V.4    Fiduccia, P.5    Farina, P.6
  • 38
    • 84883303017 scopus 로고    scopus 로고
    • Platinum-based doublet chemotherapy plus bevacizumab without bevacizumab maintenance in advanced non-small cell lung cancer (NSCLC)
    • Noroxe D.S., Wallerek S., Sorensen J.B. Platinum-based doublet chemotherapy plus bevacizumab without bevacizumab maintenance in advanced non-small cell lung cancer (NSCLC). Anticancer Res 2013, 33:3275-3278.
    • (2013) Anticancer Res , vol.33 , pp. 3275-3278
    • Noroxe, D.S.1    Wallerek, S.2    Sorensen, J.B.3
  • 39
    • 0025109821 scopus 로고
    • Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases
    • Jacquillat C., Khayat D., Banzet P., Weil M., Fumoleau P., Avril M.F., et al. Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases. Cancer 1990, 66:1873-1878.
    • (1990) Cancer , vol.66 , pp. 1873-1878
    • Jacquillat, C.1    Khayat, D.2    Banzet, P.3    Weil, M.4    Fumoleau, P.5    Avril, M.F.6
  • 40
    • 1842562211 scopus 로고    scopus 로고
    • Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
    • Avril M.F., Aamdal S., Grob J.J., Hauschild A., Mohr P., Bonerandi J.J., et al. Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study. J Clin Oncol 2004, 22:1118-1125.
    • (2004) J Clin Oncol , vol.22 , pp. 1118-1125
    • Avril, M.F.1    Aamdal, S.2    Grob, J.J.3    Hauschild, A.4    Mohr, P.5    Bonerandi, J.J.6
  • 41
    • 0037331446 scopus 로고    scopus 로고
    • A prospective randomized multicentre phase III trial of fotemustine plus whole brain irradiation versus fotemustine alone in cerebral metastases of malignant melanoma
    • Mornex F., Thomas L., Mohr P., Hauschild A., Delaunay M.M., Lesimple T., et al. A prospective randomized multicentre phase III trial of fotemustine plus whole brain irradiation versus fotemustine alone in cerebral metastases of malignant melanoma. Melanoma Res 2003, 13:97-103.
    • (2003) Melanoma Res , vol.13 , pp. 97-103
    • Mornex, F.1    Thomas, L.2    Mohr, P.3    Hauschild, A.4    Delaunay, M.M.5    Lesimple, T.6
  • 42
    • 0036208833 scopus 로고    scopus 로고
    • Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group
    • Margolin K., Atkins B., Thompson A., Ernstoff S., Weber J., Flaherty L., et al. Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group. J Cancer Res Clin Oncol 2002, 128:214-218.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 214-218
    • Margolin, K.1    Atkins, B.2    Thompson, A.3    Ernstoff, S.4    Weber, J.5    Flaherty, L.6
  • 43
    • 55749092775 scopus 로고    scopus 로고
    • Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study
    • Atkins M.B., Sosman J.A., Agarwala S., Logan T., Clark J.I., Ernstoff M.S., et al. Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study. Cancer 2008, 113:2139-2145.
    • (2008) Cancer , vol.113 , pp. 2139-2145
    • Atkins, M.B.1    Sosman, J.A.2    Agarwala, S.3    Logan, T.4    Clark, J.I.5    Ernstoff, M.S.6
  • 45
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C., Thomas L., Bondarenko I., O'Day S., Weber J., Garbe C., et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011, 364:2517-2526.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.4    Weber, J.5    Garbe, C.6
  • 46
    • 51149116051 scopus 로고    scopus 로고
    • CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS
    • Hodi F.S., Oble D.A., Drappatz J., Velazquez E.F., Ramaiya N., Ramakrishna N., et al. CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS. Nat Clin Pract Oncol 2008, 5:557-561.
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 557-561
    • Hodi, F.S.1    Oble, D.A.2    Drappatz, J.3    Velazquez, E.F.4    Ramaiya, N.5    Ramakrishna, N.6
  • 47
    • 84867332557 scopus 로고    scopus 로고
    • Clinical and radiological response of leptomeningeal melanoma after whole brain radiotherapy and ipilimumab
    • Bot I., Blank C.U., Brandsma D. Clinical and radiological response of leptomeningeal melanoma after whole brain radiotherapy and ipilimumab. J Neurol 2012, 259:1976-1978.
    • (2012) J Neurol , vol.259 , pp. 1976-1978
    • Bot, I.1    Blank, C.U.2    Brandsma, D.3
  • 48
    • 77952238391 scopus 로고    scopus 로고
    • Complete regression of a previously untreated melanoma brain metastasis with ipilimumab
    • Schartz N.E., Farges C., Madelaine I., Bruzzoni H., Calvo F., Hoos A., et al. Complete regression of a previously untreated melanoma brain metastasis with ipilimumab. Melanoma Res 2010, 20:247-250.
    • (2010) Melanoma Res , vol.20 , pp. 247-250
    • Schartz, N.E.1    Farges, C.2    Madelaine, I.3    Bruzzoni, H.4    Calvo, F.5    Hoos, A.6
  • 49
    • 84865567547 scopus 로고    scopus 로고
    • Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial
    • Di Giacomo A.M., Ascierto P.A., Pilla L., Santinami M., Ferrucci P.F., Giannarelli D., et al. Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial. Lancet Oncol 2012, 13:879-886.
    • (2012) Lancet Oncol , vol.13 , pp. 879-886
    • Di Giacomo, A.M.1    Ascierto, P.A.2    Pilla, L.3    Santinami, M.4    Ferrucci, P.F.5    Giannarelli, D.6
  • 50
    • 84860446616 scopus 로고    scopus 로고
    • Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial
    • Margolin K., Ernstoff M.S., Hamid O., Lawrence D., McDermott D., Puzanov I., et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol 2012, 13:459-465.
    • (2012) Lancet Oncol , vol.13 , pp. 459-465
    • Margolin, K.1    Ernstoff, M.S.2    Hamid, O.3    Lawrence, D.4    McDermott, D.5    Puzanov, I.6
  • 51
    • 84901633374 scopus 로고    scopus 로고
    • Efficacy and safety of ipilimumab in patients with advanced melanoma and brain metastases
    • Queirolo P., Spagnolo F., Ascierto P.A., Simeone E., Marchetti P., Scoppola A., et al. Efficacy and safety of ipilimumab in patients with advanced melanoma and brain metastases. J Neurooncol 2014, 118:109-116.
    • (2014) J Neurooncol , vol.118 , pp. 109-116
    • Queirolo, P.1    Spagnolo, F.2    Ascierto, P.A.3    Simeone, E.4    Marchetti, P.5    Scoppola, A.6
  • 52
    • 84978034236 scopus 로고    scopus 로고
    • Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma
    • Long G.V., Menzies A.M., Nagrial A.M., Haydu L.E., Hamilton A.L., Mann G.J., et al. Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma. J Clin Oncol 2011, 29:1239-1246.
    • (2011) J Clin Oncol , vol.29 , pp. 1239-1246
    • Long, G.V.1    Menzies, A.M.2    Nagrial, A.M.3    Haydu, L.E.4    Hamilton, A.L.5    Mann, G.J.6
  • 54
    • 84861083983 scopus 로고    scopus 로고
    • Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial
    • Falchook G.S., Long G.V., Kurzrock R., Kim K.B., Arkenau T.H., Brown M.P., et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 2012, 379:1893-1901.
    • (2012) Lancet , vol.379 , pp. 1893-1901
    • Falchook, G.S.1    Long, G.V.2    Kurzrock, R.3    Kim, K.B.4    Arkenau, T.H.5    Brown, M.P.6
  • 55
    • 84868120907 scopus 로고    scopus 로고
    • Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial
    • Long G.V., Trefzer U., Davies M.A., Kefford R.F., Ascierto P.A., Chapman P.B., et al. Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial. Lancet Oncol 2012, 13:1087-1095.
    • (2012) Lancet Oncol , vol.13 , pp. 1087-1095
    • Long, G.V.1    Trefzer, U.2    Davies, M.A.3    Kefford, R.F.4    Ascierto, P.A.5    Chapman, P.B.6
  • 56
    • 84893661769 scopus 로고    scopus 로고
    • Vemurafenib in patients with BRAF(V600) mutation-positive melanoma with symptomatic brain metastases: final results of an open-label pilot study
    • Dummer R., Goldinger S.M., Turtschi C.P., Eggmann N.B., Michielin O., Mitchell L., et al. Vemurafenib in patients with BRAF(V600) mutation-positive melanoma with symptomatic brain metastases: final results of an open-label pilot study. Eur J Cancer 2014, 50:611-621.
    • (2014) Eur J Cancer , vol.50 , pp. 611-621
    • Dummer, R.1    Goldinger, S.M.2    Turtschi, C.P.3    Eggmann, N.B.4    Michielin, O.5    Mitchell, L.6
  • 58
    • 84874442053 scopus 로고    scopus 로고
    • Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases
    • Mittapalli R.K., Vaidhyanathan S., Dudek A.Z., Elmquist W.F. Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases. J Pharmacol Exp Ther 2013, 344:655-664.
    • (2013) J Pharmacol Exp Ther , vol.344 , pp. 655-664
    • Mittapalli, R.K.1    Vaidhyanathan, S.2    Dudek, A.Z.3    Elmquist, W.F.4
  • 60
    • 84880322946 scopus 로고    scopus 로고
    • Case records of the Massachusetts General Hospital. Case 21-2013. A 68-year-old man with metastatic melanoma
    • Sullivan R.J., Lawrence D.P., Wargo J.A., Oh K.S., Gonzalez R.G., Piris A. Case records of the Massachusetts General Hospital. Case 21-2013. A 68-year-old man with metastatic melanoma. N Engl J Med 2013, 369:173-183.
    • (2013) N Engl J Med , vol.369 , pp. 173-183
    • Sullivan, R.J.1    Lawrence, D.P.2    Wargo, J.A.3    Oh, K.S.4    Gonzalez, R.G.5    Piris, A.6
  • 61
    • 0013071190 scopus 로고
    • Whole body irradiation; radiobiology or medicine?
    • Mole R.H. Whole body irradiation; radiobiology or medicine?. Br J Radiol 1953, 26:234-241.
    • (1953) Br J Radiol , vol.26 , pp. 234-241
    • Mole, R.H.1
  • 62
    • 0037093972 scopus 로고    scopus 로고
    • Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
    • Schouten L.J., Rutten J., Huveneers H.A., Twijnstra A. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer 2002, 94:2698-2705.
    • (2002) Cancer , vol.94 , pp. 2698-2705
    • Schouten, L.J.1    Rutten, J.2    Huveneers, H.A.3    Twijnstra, A.4
  • 63
    • 0021340544 scopus 로고
    • Brain metastases in patients with renal cell carcinoma: prognosis and treatment
    • Decker D.A., Decker V.L., Herskovic A., Cummings G.D. Brain metastases in patients with renal cell carcinoma: prognosis and treatment. J Clin Oncol 1984, 2:169-173.
    • (1984) J Clin Oncol , vol.2 , pp. 169-173
    • Decker, D.A.1    Decker, V.L.2    Herskovic, A.3    Cummings, G.D.4
  • 64
    • 54049086165 scopus 로고    scopus 로고
    • Brain metastasis from renal cell carcinoma: presentation, recurrence, and survival
    • Shuch B., La Rochelle J.C., Klatte T., Riggs S.B., Liu W., Kabbinavar F.F., et al. Brain metastasis from renal cell carcinoma: presentation, recurrence, and survival. Cancer 2008, 113:1641-1648.
    • (2008) Cancer , vol.113 , pp. 1641-1648
    • Shuch, B.1    La Rochelle, J.C.2    Klatte, T.3    Riggs, S.B.4    Liu, W.5    Kabbinavar, F.F.6
  • 65
    • 70349669267 scopus 로고    scopus 로고
    • Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters
    • Hu S., Chen Z., Franke R., Orwick S., Zhao M., Rudek M.A., et al. Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters. Clin Cancer Res 2009, 15:6062-6069.
    • (2009) Clin Cancer Res , vol.15 , pp. 6062-6069
    • Hu, S.1    Chen, Z.2    Franke, R.3    Orwick, S.4    Zhao, M.5    Rudek, M.A.6
  • 66
    • 67651201656 scopus 로고    scopus 로고
    • Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial
    • Gore M.E., Szczylik C., Porta C., Bracarda S., Bjarnason G.A., Oudard S., et al. Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial. Lancet Oncol 2009, 10:757-763.
    • (2009) Lancet Oncol , vol.10 , pp. 757-763
    • Gore, M.E.1    Szczylik, C.2    Porta, C.3    Bracarda, S.4    Bjarnason, G.A.5    Oudard, S.6
  • 67
    • 79251478764 scopus 로고    scopus 로고
    • Sunitinib in metastatic renal cell carcinoma patients with brain metastases
    • Gore M.E., Hariharan S., Porta C., Bracarda S., Hawkins R., Bjarnason G.A., et al. Sunitinib in metastatic renal cell carcinoma patients with brain metastases. Cancer 2011, 117:501-509.
    • (2011) Cancer , vol.117 , pp. 501-509
    • Gore, M.E.1    Hariharan, S.2    Porta, C.3    Bracarda, S.4    Hawkins, R.5    Bjarnason, G.A.6
  • 68
    • 77149126422 scopus 로고    scopus 로고
    • Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America
    • Stadler W.M., Figlin R.A., McDermott D.F., Dutcher J.P., Knox J.J., Miller W.H., et al. Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America. Cancer 2010, 116:1272-1280.
    • (2010) Cancer , vol.116 , pp. 1272-1280
    • Stadler, W.M.1    Figlin, R.A.2    McDermott, D.F.3    Dutcher, J.P.4    Knox, J.J.5    Miller, W.H.6
  • 70
    • 80054820244 scopus 로고    scopus 로고
    • Impact of tyrosine kinase inhibitors on the incidence of brain metastasis in metastatic renal cell carcinoma
    • Verma J., Jonasch E., Allen P., Tannir N., Mahajan A. Impact of tyrosine kinase inhibitors on the incidence of brain metastasis in metastatic renal cell carcinoma. Cancer 2011, 117:4958-4965.
    • (2011) Cancer , vol.117 , pp. 4958-4965
    • Verma, J.1    Jonasch, E.2    Allen, P.3    Tannir, N.4    Mahajan, A.5
  • 71
    • 84904720647 scopus 로고    scopus 로고
    • Targeted therapy for renal cell carcinoma with brain metastasis: overall survival and safety
    • suppl; abstr e15517
    • Bastos D., Molina A.M., Jia X., Velasco S., Patil S., Voss M.H., et al. Targeted therapy for renal cell carcinoma with brain metastasis: overall survival and safety. J Clin Oncol 2013, 31. suppl; abstr e15517.
    • (2013) J Clin Oncol , vol.31
    • Bastos, D.1    Molina, A.M.2    Jia, X.3    Velasco, S.4    Patil, S.5    Voss, M.H.6
  • 72
    • 84859155253 scopus 로고    scopus 로고
    • Symptomatic brain metastases from renal cell carcinoma during treatment with sunitinib or sorafenib
    • suppl; abstr e15023
    • Larkin J.M., Hess V., Pickering L.M., Ferguson T., Forrest R., Gore M.E. Symptomatic brain metastases from renal cell carcinoma during treatment with sunitinib or sorafenib. J Clin Oncol 2010, 28. suppl; abstr e15023.
    • (2010) J Clin Oncol , vol.28
    • Larkin, J.M.1    Hess, V.2    Pickering, L.M.3    Ferguson, T.4    Forrest, R.5    Gore, M.E.6
  • 73
    • 84892595963 scopus 로고    scopus 로고
    • The impact of tyrosine kinase inhibitors on the multimodality treatment of brain metastases from renal cell carcinoma
    • Verma J., Jonasch E., Allen P.K., Weinberg J.S., Tannir N., Chang E.L., et al. The impact of tyrosine kinase inhibitors on the multimodality treatment of brain metastases from renal cell carcinoma. Am J Clin Oncol 2013, 36:620-624.
    • (2013) Am J Clin Oncol , vol.36 , pp. 620-624
    • Verma, J.1    Jonasch, E.2    Allen, P.K.3    Weinberg, J.S.4    Tannir, N.5    Chang, E.L.6
  • 74
    • 84875742854 scopus 로고    scopus 로고
    • Prolonged survival of a patient with papillary renal cell carcinoma and brain metastases using pazopanib
    • Jacobs C., Kim D.W., Straka C., Timmerman R.D., Brugarolas J. Prolonged survival of a patient with papillary renal cell carcinoma and brain metastases using pazopanib. J Clin Oncol 2013, 31:e114-e117.
    • (2013) J Clin Oncol , vol.31
    • Jacobs, C.1    Kim, D.W.2    Straka, C.3    Timmerman, R.D.4    Brugarolas, J.5
  • 75
    • 84883464608 scopus 로고    scopus 로고
    • Prognostic factors of survival for patients with metastatic renal cell carcinoma with brain metastases treated with targeted therapy: results from the international metastatic renal cell carcinoma database consortium
    • Vickers M.M., Al-Harbi H., Choueiri T.K., Kollmannsberger C., North S., Mackenzie M., et al. Prognostic factors of survival for patients with metastatic renal cell carcinoma with brain metastases treated with targeted therapy: results from the international metastatic renal cell carcinoma database consortium. Clin Genitourin Cancer 2013, 11:311-315.
    • (2013) Clin Genitourin Cancer , vol.11 , pp. 311-315
    • Vickers, M.M.1    Al-Harbi, H.2    Choueiri, T.K.3    Kollmannsberger, C.4    North, S.5    Mackenzie, M.6
  • 76
    • 84899919807 scopus 로고    scopus 로고
    • Bevacizumab as first-line therapy for patients with brain metastases from renal carcinoma: a case series
    • Zustovich F., Ferro A., Farina P. Bevacizumab as first-line therapy for patients with brain metastases from renal carcinoma: a case series. Clin Genitourin Cancer 2014, 12:e107-e110.
    • (2014) Clin Genitourin Cancer , vol.12
    • Zustovich, F.1    Ferro, A.2    Farina, P.3
  • 77
    • 0001318359 scopus 로고    scopus 로고
    • A phase II trial of fotemustine and cisplatin in central nervous system metastases from non-small cell lung cancer
    • Cotto C., Berille J., Souquet P.J., Riou R., Croisile B., Turjman F., et al. A phase II trial of fotemustine and cisplatin in central nervous system metastases from non-small cell lung cancer. Eur J Cancer 1996, 32A:69-71.
    • (1996) Eur J Cancer , vol.32 A , pp. 69-71
    • Cotto, C.1    Berille, J.2    Souquet, P.J.3    Riou, R.4    Croisile, B.5    Turjman, F.6
  • 78
    • 0033668063 scopus 로고    scopus 로고
    • Combination chemotherapy of cisplatin, ifosfamide, and irinotecan with rhG-CSF support in patients with brain metastases from non-small cell lung cancer
    • Fujita A., Fukuoka S., Takabatake H., Tagaki S., Sekine K. Combination chemotherapy of cisplatin, ifosfamide, and irinotecan with rhG-CSF support in patients with brain metastases from non-small cell lung cancer. Oncology 2000, 59:291-295.
    • (2000) Oncology , vol.59 , pp. 291-295
    • Fujita, A.1    Fukuoka, S.2    Takabatake, H.3    Tagaki, S.4    Sekine, K.5


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