Synthesis and preliminary biological evaluation of O-2((2-[ 18F]fluoroethyl)methylamino)ethyltyrosine ([18F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging

Amino Acids

Volumn 46, Issue 8, 2014, Pages 1947-1959

  Chiotellis, Aristeidis ^a   Müller, Adrienne ^a   Weyermann, Karin ^a   Leutwiler, Dominique S ^a,b   Schibli, Roger ^a   Ametamey, Simon M ^a   Krämer, Stefanie D ^a   Mu, Linjing ^b  

^a ETH Zurich   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Amino acid transporter; Cationic amino acids; PET; SLC6A14; Tumor imaging

Indexed keywords

O (2 [18F]FLUROETHYL) LEVO TYROSINE; O 2((2 [18F]FLUOROETHYL)METHYLAMINO)ETHYLTYROSINE; TRACER; UNCLASSIFIED DRUG; AMINO ACID; AMINO ACID TRANSPORTER; FLUORINE; O-2((2-FLUOROETHYL)METHYLAMINO)ETHYLTYROSINE; RADIOPHARMACEUTICAL AGENT; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; FEMALE; FLUORINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LUNG CANCER CELL LINE; MOUSE; NCI H69 CELL LINE; NONHUMAN; NUCLEOPHILICITY; PC 3 CELL LINE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; RADIOCHEMISTRY; RADIOSYNTHESIS; SYNTHESIS; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; CANCER TRANSPLANTATION; CHEMISTRY; DIAGNOSTIC IMAGING; LUNG NEOPLASMS; MALE; METABOLISM; NUDE MOUSE; PROCEDURES; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; SCINTISCANNING; SMALL CELL LUNG CARCINOMA; TUMOR CELL LINE; XENOGRAFT;

ANIMALIA; MUS;

AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; ANIMALS; BLOOD-BRAIN BARRIER; CELL LINE, TUMOR; DIAGNOSTIC IMAGING; FEMALE; FLUORINE RADIOISOTOPES; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; POSITRON-EMISSION TOMOGRAPHY; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; RADIOPHARMACEUTICALS; SMALL CELL LUNG CARCINOMA; TRANSPLANTATION, HETEROLOGOUS; TYROSINE;

EID: 84904732264     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-014-1754-7     Document Type: Article

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