1.9μm superficially porous packing material with radially oriented pores and tailored pore size for ultra-fast separation of small molecules and biomolecules

Journal of Chromatography A

Volumn 1356, Issue , 2014, Pages 148-156

  Min, Yi ^a,b   Jiang, Bo ^a,b   Wu, Ci ^a,b   Xia, Simin ^a,b   Zhang, Xiaodan ^a   Liang, Zhen ^a   Zhang, Lihua ^a   Zhang, Yukui ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

1.9 m; Peptides; Pore size; Proteins; Radially oriented pores; Superficially porous silica particles

Indexed keywords

BIOMOLECULES; ESCHERICHIA COLI; MESOPOROUS MATERIALS; NAPHTHALENE; PEPTIDES; PORE SIZE; PROTEINS; SILICA;

CHROMATOGRAPHIC PERFORMANCE; HIGH-RESOLUTION SEPARATIONS; HIGH-THROUGHPUT ANALYSIS; MESOPOROUS STRUCTURES; POROUS PACKING MATERIAL; POROUS SILICA; RADIALLY ORIENTED PORES; SEPARATION OF SMALL MOLECULES;

SEPARATION;

ALKYLBENZENE; SILICATE;

ARTICLE; COATED PARTICLE; CONCENTRATION (PARAMETERS); HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; MATERIAL COATING; NONPOROUS SILICA PARTICLE; PARTICLE SIZE; POROUS PACKING MATERIAL; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE; THICKNESS;

ESCHERICHIA COLI;

1.9ΜM; PEPTIDES; PORE SIZE; PROTEINS; RADIALLY ORIENTED PORES; SUPERFICIALLY POROUS SILICA PARTICLES;

ADSORPTION; CHROMATOGRAPHY, GEL; MICROSPHERES; PARTICLE SIZE; PEPTIDE FRAGMENTS; POROSITY; SERUM ALBUMIN, BOVINE; SILICON DIOXIDE; SURFACE PROPERTIES;

EID: 84904724191     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.06.049     Document Type: Article

References (27)

1. Gritti F., Guiochon G. Perspectives on the evolution of the column efficiency in liquid chromatography. Anal. Chem. 2013, 85:3017-3035.
2. Wang F., Min Y., Geng X. Fast separations of intact proteins by liquid chromatography. J. Sep. Sci. 2012, 35:3033-3045.
3. Unger K.K., Liapis A.I. Adsorbents and columns in analytical high-performance liquid chromatography: A perspective with regard to development and understanding. J. Sep. Sci. 2012, 35:1201-1212.
4. Fekete S., Oláh E., Fekete J. Fast liquid chromatography: The domination of core-shell and very fine particles. J. Chromatogr. A 2012, 1228:57-71.
5. Kirkland J.J., Schuster S.A., Johnson W.L., Boyes B.E. Fused-core particle technology in high-performance liquid chromatography: An overview. J. Pharm. Anal. 2013, 3:303-312.
6. Guiochon G., Gritti F. Shell particles, trials, tribulations and triumphs. J. Chromatogr. A 2011, 1218:1915-1938.
7. Horvath C.G., Preiss B.A., Lipsky S.R. Fast liquid chromatography: An investigation of operating parameters and the separation of nucleotides on pellicular ion exchangers. Anal. Chem. 1967, 39:1422-1428.
8. Kirkland J.J. Superficially porous silica microspheres for the fast high-performance liquid chromatography of macromolecules. Anal. Chem. 1992, 64:1239-1245.
9. Omamogho J.O., Hanrahan J.P., Tobin J., Glennon J.D. Structural variation of solid core and thickness of porous shell of 1.7μm core-shell silica particles on chromatographic performance: Narrow bore columns. J. Chromatogr. A 2011, 1218:1942-1953.
10. Kirkland J.J., Langlois T.J., DeStefano J.J. Fused core particles for HPLC columns. American Lab. 2007, 39:18-21.
11. Kirkland J.J., Truszkowski F.A., Dilks C.H., Engel G.S. Superficially porous silica microspheres for fast high-performance liquid chromatography of macromolecules. J. Chromatogr. A 2000, 890:3-13.
12. Fairchild J.N., Walworth M.J., Horváth K., Guiochon G. Correlation between peak capacity and protein sequence coverage in proteomics analysis by liquid chromatography-mass spectrometry/mass spectrometry. J. Chromatogr. A 2010, 1217:4779-4783.
13. Fekete S., Ganzler K., Fekete J. Efficiency of the new sub-2μm core-shell (Kinetex™) column in practice, applied for small and large molecule separation. J. Pharm. Biomed. Anal. 2011, 54:482-490.
14. Oláh E., Fekete S., Fekete J., Ganzler K. Comparative study of new shell-type, sub-2μm fully porous and monolith stationary phases, focusing on mass-transfer resistance. J. Chromatogr. A 2010, 1217:3642-3653.
15. Fekete S., Guillarme D. Possibilities of new generation columns packed with 1.3μm core-shell particles in gradient elution mode. J. Chromatogr. A 2013, 1320:86-95.
16. Blue L.E., Jorgenson J.W. 1.1μm superficially porous particles for liquid chromatography. Part I: Synthesis and particle structure characterization. J. Chromatogr. A 2011, 1218:7989-7995.
17. J.O. Omamogho, J.D. Glennon, A process for preparing silica microparticles, Patent Pub. No.: WO/2010/061367.
18. Dong H., Brennan J.D. One-pot synthesis of silica core-shell particles with double shells and different pore orientations from their nonporous counterparts. J. Mater. Chem. 2012, 22:13197-13203.
19. Omamogho J.O., Glennon J.D. Comparison between the efficiencies of sub-2μm C18 particles packed in narrow bore columns. Anal. Chem. 2011, 83:1547-1556.
20. Fanigliulo A., Cabooter D., Bellazzi G., Tramarin D., Allieri B., Rottigni A., Desmet G. Comparison of performance of high-performance liquid chromatography columns packed with superficially and fully porous 2.5μm particles using kinetic plots. J. Sep. Sci. 2010, 33:3655-3665.
21. Liekens A., Denayer J., Desmet G. Experimental investigation of the difference in B-term dominated band broadening between fully porous and porous-shell particles for liquid chromatography using the Effective Medium Theory. J. Chromatogr. A 2011, 1218:4406-4416.
22. Qu Y., Xia S., Yuan H., Wu Q., Li M., Zou L., Zhang L., Liang Z., Zhang Y. Integrated sample pretreatment system for N-linked glycosylation site profiling with combination of hydrophilic interaction chromatography and PNGase F immobilized enzymatic reactor via a strong cation exchange precolumn. Anal. Chem. 2011, 83:7457-7463.
23. Bogush G.H., Tracy M.A., Zukoski C.F. Preparation of monodisperse silica particles: control of size and mass fraction. J. Non-Cryst. Solids 1988, 104:95-106.
24. Gritti F., Guiochon G. On the extra-column band-broadening contributions of modern, very high pressure liquid chromatographs using 2.1mm I.D. columns packed with sub-2μm particles. J. Chromatogr. A 2010, 1217:7677-7689.
25. Schustter S.A., Wagner B.M., Boyes B.E., Kirkland J.J. Wider pore superficially porous particles for peptide separations by HPLC. J. Chromatogr. Sci. 2010, 48:566-571.
26. De Vos J., Stassen C., Vaast A., Desmet G., Eeltink S. High-resolution separations of tryptic digest mixtures using core-shell particulate columns operated at 1200bar. J. Chromatogr. A 2012, 1264:57-62.
27. Yang X., Ma L., Carr P.W. High temperature fast chromatography of proteins using a silica-based stationary phase with greatly enhanced low pH stability. J. Chromatogr. A 2005, 1079:213-220.