Abnormal splicing of NEDD4 in myotonic dystrophy type 2: Possible link to statin adverse reactions

American Journal of Pathology

Volumn 184, Issue 8, 2014, Pages 2322-2332

  Screen, Mark ^a   Jonson, Per Harald ^a   Raheem, Olayinka ^b   Palmio, Johanna ^b   Laaksonen, Reijo ^c   Lehtimäki, Terho ^c   Sirito, Mario ^d   Krahe, Ralf ^d,e   Hackman, Peter ^a   Udd, Bjarne ^a,b,f  

^a UNIVERSITY OF HELSINKI   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d UNIVERSITY OF TEXAS   (United States)

^e UNIVERSITY OF TEXAS   (United States)

^f VAASA CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SIMVASTATIN; SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1B1; UBIQUITIN PROTEIN LIGASE NEDD4; ESCRT PROTEIN; NEDD4 UBIQUITIN PROTEIN LIGASES; ORGANIC ANION TRANSPORTER; PTEN PROTEIN, HUMAN; SLCO1B1 PROTEIN, HUMAN; TRANSCRIPTOME; UBIQUITIN PROTEIN LIGASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERLIPIDEMIA; MALE; MIDDLE AGED; MUSCLE BIOPSY; MUSCLE CONTRACTION; MYOTONIC DYSTROPHY; NEURAL STEM CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; TRANSCRIPTION TERMINATION; UBIQUITINATION; COMPLICATION; DNA MICROARRAY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; GENOTYPE; HYPERLIPIDEMIAS; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADULT; BLOTTING, WESTERN; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENOTYPE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERLIPIDEMIAS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUSCLE, SKELETAL; MYOTONIC DYSTROPHY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGANIC ANION TRANSPORTERS; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA SPLICING; SIGNAL TRANSDUCTION; TRANSCRIPTOME; UBIQUITIN-PROTEIN LIGASES;

EID: 84904678832     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.04.013     Document Type: Article

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