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Volumn 70, Issue 2, 2014, Pages 535-546

Effects of warfarin and L-carnitine on hemostatic function and oxidative stress in streptozotocin-induced diabetic rats

Author keywords

Coagulation; Diabetes mellitus; L Carnitine; Oxidative stress; Warfarin

Indexed keywords

ANTIOXIDANT; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 7; CARNITINE; CATALASE; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEMOGLOBIN A1C; INSULIN; MALONALDEHYDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN C; SUPEROXIDE DISMUTASE; WARFARIN; STREPTOZOCIN;

EID: 84904677293     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-014-0333-4     Document Type: Article
Times cited : (16)

References (46)
  • 1
    • 3142534320 scopus 로고    scopus 로고
    • Evaluation of some biochemical changes in diabetic patients
    • DOI 10.1016/j.cccn.2004.03.030, PII S0009898104001731
    • Abou-Seif MA, Youssef AA (2004) Evaluation of some biochemical changes in diabetic patients. Clin Chem Acta 346:161-170 (Pubitemid 38901047)
    • (2004) Clinica Chimica Acta , vol.346 , Issue.2 , pp. 161-170
    • Abou-Seif, M.A.1    Youssef, A.-A.2
  • 3
    • 45949103309 scopus 로고    scopus 로고
    • Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • DOI 10.1378/chest.08-0670
    • Ansell J, Hirsh J, Hylek E et al (2008) Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians evidence-based clinical practice guidelines (8th Edition). Chest 133(6 Suppl):160S-198S (Pubitemid 351892967)
    • (2008) Chest , vol.133 , Issue.6 SUPPL. 6
    • Ansell, J.1    Hirsh, J.2    Hylek, E.3    Jacobson, A.4    Crowther, M.5    Palareti, G.6
  • 4
    • 0033832185 scopus 로고    scopus 로고
    • Elevation of fibrinogen and thrombin-antithrombin III complex levels of type 2 diabetes mellitus patients with retinopathy and nephropathy
    • Asakawa H, Tokunaga K, Kawakami F (2000) Elevation of fibrinogen and thrombin-antithrombin III complex levels of type 2 diabetes mellitus patients with retinopathy and nephropathy. J Diabet Complicat 14:121-126
    • (2000) J Diabet Complicat , vol.14 , pp. 121-126
    • Asakawa, H.1    Tokunaga, K.2    Kawakami, F.3
  • 5
    • 0020789178 scopus 로고
    • Nonenzymatic glycosylation reduces the susceptibility of fibrin to degradation by plasmin
    • Brownlee M, Vlassara H, Cerami A (1983) Nonenzymatic glycosylation reduces the susceptibility of fibrin to degradation by plasmin. Diabetes 32:600-604
    • (1983) Diabetes , vol.32 , pp. 600-604
    • Brownlee, M.1    Vlassara, H.2    Cerami, A.3
  • 6
    • 0023553761 scopus 로고
    • Induced hyperglycemia alters antithrombin III activity but not its plasma concentration in healthy normal subjects
    • Ceriello A, Giugliano D, Quatraro A et al (1987) Induced hyperglycemia alters antithrombin III activity but not its plasma concentration in healthy normal subjects. Diabetes 36:320-323 (Pubitemid 18028423)
    • (1987) Diabetes , vol.36 , Issue.3 , pp. 320-323
    • Ceriello, A.1    Giugliano, D.2    Quatraro, A.3    Consoli, G.4    Stante, A.5    Dello, R.P.6    Donofrio, F.7
  • 7
    • 0029030689 scopus 로고
    • Coagulation activation in type 2 diabetes mellitus: The higher coronary risk of female diabetic patients
    • Chan P, Pan WH (1995) Coagulation activation in type 2 diabetes mellitus: the higher coronary risk of female diabetic patients. Diabet Med 12:504-507
    • (1995) Diabet Med , vol.12 , pp. 504-507
    • Chan, P.1    Pan, W.H.2
  • 8
    • 0023899986 scopus 로고
    • The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activitywith warfarin
    • Choonara IA, Malia RG, Haynes BP et al (1988) The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activitywith warfarin. Br J Clin Pharmacol 25:1-7
    • (1988) Br J Clin Pharmacol , vol.25 , pp. 1-7
    • Choonara, I.A.1    Malia, R.G.2    Haynes, B.P.3
  • 9
    • 33644754588 scopus 로고    scopus 로고
    • The urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats
    • DOI 10.1124/jpet.105.094821
    • Clozel M, Hess P, Qiu C, Ding SS, Rey M (2006) The urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats. J Pharmacol Exp Ther 316:1115-1121 (Pubitemid 43345285)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.316 , Issue.3 , pp. 1115-1121
    • Clozel, M.1    Hess, P.2    Qiu, C.3    Ding, S.-S.4    Rey, M.5
  • 12
    • 0024468052 scopus 로고
    • Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties
    • Esposito C, Gerlach H, Brett J, Stern D, Vlassara H (1989) Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties. J Exp Med 170:1387-1407 (Pubitemid 19250701)
    • (1989) Journal of Experimental Medicine , vol.170 , Issue.4 , pp. 1387-1407
    • Esposito, C.1    Gerlach, H.2    Brett, J.3    Stern, D.4    Vlassara, H.5
  • 13
    • 0342520832 scopus 로고    scopus 로고
    • Pancreatic nitric oxide and oxygen free radicals in the early stages of streptozotocininduced diabetes mellitus in the rat
    • Gonzalez E, Rosello-Catafau J, Jawerbaum A, Sinner D, Pustovrh C, Vela J et al (2000) Pancreatic nitric oxide and oxygen free radicals in the early stages of streptozotocininduced diabetes mellitus in the rat. Braz J Med Biol Res 33:1335-1342
    • (2000) Braz J Med Biol Res , vol.33 , pp. 1335-1342
    • Gonzalez, E.1    Rosello-Catafau, J.2    Jawerbaum, A.3    Sinner, D.4    Pustovrh, C.5    Vela, J.6
  • 15
    • 30344486998 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiovascular complications
    • DOI 10.1016/j.freeradbiomed.2005.06.018, PII S0891584905003503
    • Jay D, Hitomi H, Griendling KK (2006) Oxidative stress and diabetic cardiovascular complications. Free Radic Biol Med 40:183-192 (Pubitemid 43069343)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.2 , pp. 183-192
    • Jay, D.1    Hitomi, H.2    Griendling, K.K.3
  • 16
    • 79955582748 scopus 로고    scopus 로고
    • Lcarnitine protects plasma components against oxidative alterations
    • Kolodziejczyk J, Saluk-Juszczak J, Wachowicz B (2011) Lcarnitine protects plasma components against oxidative alterations. Nutrition 27:693-699
    • (2011) Nutrition , vol.27 , pp. 693-699
    • Kolodziejczyk, J.1    Saluk-Juszczak, J.2    Wachowicz, B.3
  • 17
    • 84904672144 scopus 로고    scopus 로고
    • Effect of systemic carnitine therapy on serum fibronectin level in diabetic rats
    • Article in Press
    • Komurcu E, Ozkan OF, Kemik AS, Nusran G, Asik M, Arslan E (2013) Effect of systemic carnitine therapy on serum fibronectin level in diabetic rats. J Surg Res xxx:1-6 (Article in Press)
    • (2013) J Surg Res , vol.30 , pp. 1-6
    • Komurcu, E.1    Ozkan, O.F.2    Kemik, A.S.3    Nusran, G.4    Asik, M.5    Arslan, E.6
  • 18
    • 34247394257 scopus 로고    scopus 로고
    • Oxidative stress and diabetic retinopathy
    • Kowluru RA, Chan PS (2007) Oxidative stress and diabetic retinopathy. Exp Diabetes Res 2007:Article ID 43603
    • (2007) Exp Diabetes Res , vol.2007 , pp. 43603
    • Kowluru, R.A.1    Chan, P.S.2
  • 19
    • 17744377972 scopus 로고    scopus 로고
    • Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney
    • DOI 10.1111/j.1523-1755.2005.00274.x
    • Lee EA, Seo JY, Jiang Z, Yu MR, Kwon MK, Ha H, Lee HB (2005) Reactive oxygen speciesmediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney. Kidney Int 67:1762-1771 (Pubitemid 40577711)
    • (2005) Kidney International , vol.67 , Issue.5 , pp. 1762-1771
    • Eun, A.L.1    Ji, Y.S.2    Jiang, Z.3    Mi, R.Y.4    Min, K.K.5    Ha, H.6    Hi, B.L.7
  • 20
    • 0027420315 scopus 로고
    • Anticoagulant and estrogenic effects of two new 17β-aminoestrogens, butolame [17β-(4-hydroxy-1- butylamino)-1,3,5(10)-estratrien-3-ol] and pentolame [17β-(5-hydroxy-1-pentylamino)-1,3,5(10)-estratrien-3-ol]
    • Lemini C, Rubio-Póo C, Silva G, Garcia-Mondragon J, Zavala E, Mendoza-Patiño N, Castro D, Cruz-Almanza R, Mandoki JJ (1993) Anticoagulant and estrogenic effects of two new 17β-aminoestrogens, butolame [17β-(4-hydroxy-1- butylamino)-1,3,5(10)-estratrien-3-ol] and pentolame [17β-(5-hydroxy-1-pentylamino)-1,3,5(10)-estratrien-3-ol]. Steroids 58:457-461
    • (1993) Steroids , vol.58 , pp. 457-461
    • Lemini, C.1    Rubio-Póo, C.2    Silva, G.3    Garcia-Mondragon, J.4    Zavala, E.5    Mendoza-Patiño, N.6    Castro, D.7    Cruz-Almanza, R.8    Mandoki, J.J.9
  • 22
    • 1142274548 scopus 로고    scopus 로고
    • Identification of the gene for vitamin K epoxide reductase
    • DOI 10.1038/nature02254
    • Li T, Chang CY, Jin DY, Lin PJ, Khvorova A, Stafford DW (2004) Identification of the gene for vitamin K epoxide reductase. Nature 427(6974):541-544 (Pubitemid 38209111)
    • (2004) Nature , vol.427 , Issue.6974 , pp. 541-544
    • Li, T.1    Chang, C.-Y.2    Jin, D.-Y.3    Lin, P.-J.4    Khvorova, A.5    Stafford, D.W.6
  • 25
    • 24144502077 scopus 로고    scopus 로고
    • Effect of L-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons
    • DOI 10.1373/clinchem.2005.050328
    • Michno A, Raszeja-Specht A, Jankowska-Kulawy A, Pawelczyk T, Szutowicz A (2005) Effect of L-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons. Clin Chem 51:1673-1682 (Pubitemid 41233103)
    • (2005) Clinical Chemistry , vol.51 , Issue.9 , pp. 1673-1682
    • Michno, A.1    Raszeja-Specht, A.2    Jankowska-Kulawy, A.3    Pawelczyk, T.4    Szutowicz, A.5
  • 26
    • 77956379970 scopus 로고    scopus 로고
    • Diabetes and the platelet: Toward new therapeutic paradigms for diabetic atherothrombosis
    • Morel O, Kessler L, Ohlmann P, Bareiss P (2010) Diabetes and the platelet: toward new therapeutic paradigms for diabetic atherothrombosis. Atherosclerosis 212(2):367-376
    • (2010) Atherosclerosis , vol.212 , Issue.2 , pp. 367-376
    • Morel, O.1    Kessler, L.2    Ohlmann, P.3    Bareiss, P.4
  • 27
    • 0004460792 scopus 로고
    • Effects of adenosine nucleotides on platelet aggregation and clotting time
    • Mustard JF, Hegard TB, RowSell HC (1964) Effects of adenosine nucleotides on platelet aggregation and clotting time. J Lab Clin Med 64:548
    • (1964) J Lab Clin Med , vol.64 , pp. 548
    • Mustard, J.F.1    Hegard, T.B.2    RowSell, H.C.3
  • 28
    • 68149137642 scopus 로고    scopus 로고
    • Prothrombine time and partial thromboplastin time assay considerations
    • Ng VL (2009) Prothrombine time and partial thromboplastin time assay considerations. Clin Lab Med 29:253-263
    • (2009) Clin Lab Med , vol.29 , pp. 253-263
    • Ng, V.L.1
  • 29
    • 69249124248 scopus 로고    scopus 로고
    • Atherothrombosis and oxidative stress: The connection and correlation in diabetes
    • Nwose EU, Jelinek HF, Richards RS, Tinley P, Kerr PG (2009) Atherothrombosis and oxidative stress: the connection and correlation in diabetes. Redox Rep 14:55-60
    • (2009) Redox Rep , vol.14 , pp. 55-60
    • Nwose, E.U.1    Jelinek, H.F.2    Richards, R.S.3    Tinley, P.4    Kerr, P.G.5
  • 30
    • 0023770113 scopus 로고
    • Free radicals and diabetes
    • Oberley LW (1988) Free radicals and diabetes. Free Radic Biol Med 5:113-124
    • (1988) Free Radic Biol Med , vol.5 , pp. 113-124
    • Oberley, L.W.1
  • 32
    • 0034769470 scopus 로고    scopus 로고
    • Carnitine as a free radical scavenger in aging
    • Rani PJA, Panneerselvam C (2001) Carnitine as a free radical scavenger in aging. Exp Gerontol 36:1713-1726
    • (2001) Exp Gerontol , vol.36 , pp. 1713-1726
    • Rani, P.J.A.1    Panneerselvam, C.2
  • 34
    • 84860668300 scopus 로고    scopus 로고
    • Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: Evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency
    • Ringseis R, Keller J, Eder K (2012) Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency. Eur J Nutr 51:1-18
    • (2012) Eur J Nutr , vol.51 , pp. 1-18
    • Ringseis, R.1    Keller, J.2    Eder, K.3
  • 36
    • 23244440905 scopus 로고    scopus 로고
    • Protective effects of L-carnitine on myocardium of experimentally diabetic rats with additional ischaemia and reperfusion
    • DOI 10.1007/s00706-005-0321-z
    • Schneider R, Löster H, Aust W, Craatz S, Welt K, Fitzl G (2005) Protective effects of L-carnitine on myocardium of experimentally diabetic rats with additional ischaemia and reperfusion. Monatsh Chem 136:1467-1481 (Pubitemid 41095372)
    • (2005) Monatshefte fur Chemie , vol.136 , Issue.8 , pp. 1467-1481
    • Schneider, R.1    Loster, H.2    Aust, W.3    Craatz, S.4    Welt, K.5    Fitzl, G.6
  • 37
    • 0030916386 scopus 로고    scopus 로고
    • Acetyl-L-carnitine effects on nerve conduction and glycemic regulation in experimental diabetes
    • Soneru IL, Khan T, Orfalian Z, Abraira C (1997) Acetyl-Lcarnitine effects on nerve conduction and glycemic regulation in experimental diabetes. Endocr Res 23:27-36 (Pubitemid 27272708)
    • (1997) Endocrine Research , vol.23 , Issue.1-2 , pp. 27-36
    • Soneru, I.L.1    Khan, T.2    Orfalian, Z.3    Abraira, C.4
  • 38
    • 0027406191 scopus 로고
    • Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the multiple risk factor intervention trial
    • Stamler J, Vaccaro O, Neaton JD, Wentworth D (1993) Diabetes, other risk factors and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diab Care 16:434-444 (Pubitemid 23046633)
    • (1993) Diabetes Care , vol.16 , Issue.2 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 39
    • 33748288144 scopus 로고    scopus 로고
    • Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans
    • DOI 10.2337/db05-1543
    • Stegenga M, van der Crabben S, Levi M et al (2006) Hyperglycemia stimulates coagulation, whereas hyperinsulinaemia impairs fibrinolysis in healthy individuals. Diabetes 55:1807-1812 (Pubitemid 44324136)
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1807-1812
    • Stegenga, M.E.1    Van Der, C.S.N.2    Levi, M.3    De Vos, A.F.4    Tanck, M.W.5    Sauerwein, H.P.6    Van Der, P.T.7
  • 40
    • 33847091642 scopus 로고    scopus 로고
    • Intermittent fasting prevents the progression of type I diabetic nephropathy in rats and changes the expression of Sir2 and p53
    • DOI 10.1016/j.febslet.2007.02.006, PII S001457930700155X
    • Tikoo K, Tripathi DN, Kabra DG, Sharma V, Gaikwad AB (2007) Intermittent fasting prevents the progression of type I diabetic nephropathy in rats and changes the expression of Sir2 and p53. FEBS Lett 581(5):1071-1078 (Pubitemid 46282743)
    • (2007) FEBS Letters , vol.581 , Issue.5 , pp. 1071-1078
    • Tikoo, K.1    Tripathi, D.N.2    Kabra, D.G.3    Sharma, V.4    Gaikwad, A.B.5
  • 41
    • 27244441650 scopus 로고    scopus 로고
    • Effect of L-carnitine on diabetogenic action of streptozotocin in rats
    • PII N26040522
    • Uysal N, Yalaz G, Acikgoz O, Gonenc S, Kayatekin BM (2005) Effect of L-carnitine on diabetogenic action of streptozotocin in rats. Neuro Endocrinol Lett 26(4):419-422 (Pubitemid 41518788)
    • (2005) Neuroendocrinology Letters , vol.26 , Issue.4 , pp. 419-422
    • Uysal, N.1    Yalaz, G.2    Acikgoz, O.3    Gonenc, S.4    Kayatekin, B.M.5
  • 43
    • 0024212888 scopus 로고
    • Demonstration of altered antithrombin III activity due to nonenzymatic glycosylation at glucose concentration expected to be encountered in severely diabetic patients
    • Villanueva GB, Allen N (1988) Demonstration of altered anti thrombin III activity due to non enzymatic glycosylation at glucose concentration expected to be encountered in severely diabetic patients. Diabetes 37:1103-1107 (Pubitemid 19033593)
    • (1988) Diabetes , vol.37 , Issue.8 , pp. 1103-1107
    • Villanueva, G.B.1    Allen, N.2
  • 44
    • 0025853670 scopus 로고
    • Protein glycation and oxidative stress in diabetes mellitus and ageing
    • Wolff SP, Jiang ZY, Hunt JV (1991) Protein glycation and oxidative stress in diabetes mellitus and ageing. Free Radic Biol Med 10:339-352 (Pubitemid 121003905)
    • (1991) Free Radical Biology and Medicine , vol.10 , Issue.5 , pp. 339-352
    • Wolff, S.P.1    Jiang, Z.Y.2    Hunt, J.V.3


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