Neuropsychological performance of methadone-maintained opiate users

Journal of Psychopharmacology

Volumn 28, Issue 8, 2014, Pages 789-799

  Wang, Grace Y ^a   Wouldes, Trecia A ^a   Kydd, Rob ^a   Jensen, Maree ^a   Russell, Bruce R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

cognitive impairment; Methadone maintenance; neuropsychological function; opiates

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALCOHOL; AMPHETAMINE DERIVATIVE; BARBITURIC ACID DERIVATIVE; CANNABIS; COCAINE; DIAMORPHINE; METHADONE; NICOTINE; OPIATE; PSYCHEDELIC AGENT;

ADULT; ARTICLE; ATTENTION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; EXECUTIVE FUNCTION; FEMALE; HUMAN; INFORMATION PROCESSING; MALE; MEDICAL HISTORY; METHADONE TREATMENT; NEUROPSYCHOLOGICAL TEST; OPIATE ADDICTION; PRIORITY JOURNAL; SUBSTANCE USE; SWITCHING OF ATTENTION TASK; TASK PERFORMANCE; ADOLESCENT; ADVERSE EFFECTS; CASE CONTROL STUDY; CHEMICALLY INDUCED; COGNITIVE DEFECT; COMPLICATION; DRUG EFFECTS; DRUG USE; MIDDLE AGED; NORMAL HUMAN; OPIATE SUBSTITUTION TREATMENT; OPIOID-RELATED DISORDERS; PSYCHOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; ATTENTION; CASE-CONTROL STUDIES; COGNITION DISORDERS; DRUG USERS; EXECUTIVE FUNCTION; FEMALE; HEALTHY VOLUNTEERS; HUMANS; MALE; METHADONE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OPIATE SUBSTITUTION TREATMENT; OPIOID-RELATED DISORDERS; YOUNG ADULT;

EID: 84904647077     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881114538541     Document Type: Article

References (73)

1. Aharonovich E, Nunes E, Hasin D. Cognitive impairment, retention and abstinence among cocaine abusers in cognitive-behavioral treatment. Drug Alcohol Depend. 2003 ; 71: 207-211
2. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition - Text Revision (DSMIV-TR). USA: American Psychiatric Association ; 2000 :
3. Appel P, Gordon N.. Digit-symbol performance in methadone-treated ex-heroin addicts. Am J Psychiatry. 1976 ; 133: 1337-1340
4. Appel PW. Sustained attention in methadone patients. Subst Use Misuse. 1982 ; 17: 1313-1327
5. Arbuthnott K, Frank J. Trail Making Test, Part B as a measure of executive control: Validation using a set-switching paradigm. J Clin Exp Neuropsychol. 2000 ; 22: 518-528
6. Argeriou M, McCarty D, Mulvey K, et al. Use of the addiction severity index with homeless substance abusers. J Subst Abuse Treat. 1994 ; 11: 359-365
7. Baldacchino A, Balfour DJK, Passetti F, et al. Neuropsychological consequences of chronic opioid use: A quantitative review and meta-analysis. Neurosci Biobehav Rev. 2012 ; 36: 2056-2068
8. Ball JC, Lange WR, Myers CP, et al. Reducing the risk of AIDS through methadone maintenance treatment. J Health Soc Behav. 1988 ; 29: 214-226
9. Blake AD, Bot G, Freeman JC, et al. Differential opioid agonist regulation of the mouse opioid receptor. J Biol Chem. 1997 ; 272: 782-790
10. Clair J, Martin L, Bond AJ, et al. An experimental study of aggressive and neutral interpretative bias in opiate-dependent and opiate-abstinent men. J Psychopharmacol. 2009 ; 23: 428-435
11. Clark CR, Paul RH, Williams LM, et al. Standardized assessment of cognitive functioning during development and aging using an automated touchscreen battery. Arch Clin Neuropsychol. 2006 ; 21: 449-467
12. Cohen J Statistical Power Analysis for the Behavioral Sciences. 1988 ) Statistical Power Analysis for the Behavioral Sciences. 2nd ed.Hillsdale, New Jersey: Lawrence Earlbaum Associates. Hillsdale, New Jersey: Lawrence Earlbaum Associates ; 1988 :
13. Conca AJ, Worthen DR. Nonprescription drug abuse. J Pharm Pract. 2012 ; 25: 13-21
14. Curran HV, Bolton J, Wanigaratne S, et al. Additional methadone increases craving for heroin: A double-blind, placebo-controlled study of chronic opiate users receiving methadone substitution treatment. Addiction. 1999 ; 94: 665-674
15. Curran HV, Kleckham J, Bearn J, et al. Effects of methadone on cognition, mood and craving in detoxifying opiate addicts: A dose-response study. Psychopharmacology. 2001 ; 154: 153-160
16. Danion JM, Weingartner H, File SE, et al. Pharmacology of human memory and cognition: Illustrations from the effects of benzodiazepines and cholinergic drugs. J Psychopharmacol. 1993 ; 7: 371-377
17. Darke S, Sims J, McDonald S, et al. Cognitive impairment among methadone maintenance patients. Addiction. 2000 ; 95: 687-695
18. Davis PE, Liddiard H, McMillan TM. Neuropsychological deficits and opiate abuse. Drug Alcohol Depend. 2002 ; 67: 105-108
19. Day E, Strang J. Outpatient versus inpatient opioid detoxification: A randomized controlled trial. J Subst Abuse Treat. 2011 ; 40: 56-66
20. De Quervain DJF, Roozendaal B, McGaugh JL. Stress and glucocorticoids impair retrieval of long-term spatial memory. Nature. 1998 ; 394: 787-790
21. Ersche KD, Sahakian BJ. The neuropsychology of amphetamine and opiate dependence: Implications for treatment. Neuropsychology Review. 2007 ; 17: 317-336
22. Ersche KD, Roiser JP, Clark L, et al. Punishment induces risky decision-making in methadone-maintained opiate users but not in heroin users or healthy volunteers. Neuropsychopharmacology. 2005 ; 30: 2115-2124
23. European Monitoring Centre for Drugs and Drug Addiction (2012) Table HSR-3. Estimated number of clients in methadone treatment and of all clients receiving any opioid substitution treatment (OST). Available at: http://www.emcdda.europa.eu/stat12. (accessed 27 May 2013).
24. Fingelkurts AA, Fingelkurts AA, Kivisaari R, et al. Methadone restores local and remote EEG functional connectivity in opioid. Int J Neurosci. 2009 ; 119: 1469-1493
25. Gibson DR, Flynn NM, McCarthy JJ. Effectiveness of methadone treatment in reducing HIV risk behavior and HIV seroconversion among injecting drug users. AIDS. 1999 ; 13: 1807-1818
26. Gordon NB. Reaction-times of methadone treated ex heroin addicts. Psychopharmacology. 1970 ; 16: 337-344
27. Gossop M, Stewart D, Browne N, et al. Factors associated with abstinence, lapse or relapse to heroin use after residential treatment: Protective effects of coping responses. Addiction. 2002 ; 97: 1259-1267
28. Grevert P, Masover B, Goldstein A. Failure of methadone and levomethadyl acetate (levo-alpha-acetylmethadol, LAAM) maintenance to affect memory. Arch Gen Psychiatry. 1977 ; 34: 849-853
29. Gritz ER, Shiffman SM, Jarvik ME, et al. Physiological and psychological effects of methadone in man. Arch Gen Psychiatry. 1975 ; 32: 237-242
30. Heffelfinger AK, Newcomer JW. Glucocorticoid effects on memory function over the human life span. Dev Psychopathol. 2001 ; 13: 491-513
31. James B, Wayne H, Karen B. Changes in criminal activity after entering methadone maintenance. Br J Addict. 2006 ; 87: 251-258
32. Joseph H, Stancliff S, Langrod J. Methadone maintenance treatment (MMT): A review of historical and clinical issues. Mt Sinai J Med. 2000 ; 67: 347-364
33. Jun H, Mohammed S, Hussaini Q, et al. Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders. Neural Plasticity. 2012 ; vol. 2012: 20
34. Kemp AH, Cooper N, Hermens G, et al. Toward an integrated profile of emotional intelligence: Introducing a brief measure. J Integr Neurosci. 2005 ; 4: 41-61
35. Kessler R, Ustün T. The World Mental Health (WMH) Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI). Int J Methods Psychiatr Res. 2004 ; 13: 93-121
36. Kirschbaum C, Wolf OT, May M, et al. Stress- and treatment-induced elevations of cortisol levels associated with impaired declarative memory in healthy adults. Life Sci. 1996 ; 58: 1475-1483
37. Kouri E, Lukas S, Mendelson J. P300 assessment of opiate and cocaine users: Effects of detoxification and buprenorphine treatment. Biol Psychiatry. 1996 ; 40: 617-628
38. Kreek M. Opioid receptors: Some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases. Neurochem Res. 1996 ; 21: 1469-1488
39. Kreek MJ, Koob GF. Drug dependence: Stress and dysregulation of brain reward pathways. Drug Alcohol Depend. 1998 ; 51: 23-47
40. Lee S, Kawachi I, Berkman LF, et al. Education, other socioeconomic indicators, and cognitive function. Am J Epidemiol. 2002 ; 157: 712-720
41. Leonhard C, Mulvey K, Gastfriend D, et al. The Addiction Severity Index: A field study of internal consistency and validity. J Subst Use. 2000 ; 18: 129-135
42. Liu J, Liao X, Gong Z, et al. The difference between methadone and morphine in regulation of -opioid receptors underlies the antagonistic effect of methadone on morphine-mediated cellular actions. Eur J Pharmacol. 1999 ; 373: 233-239
43. Loeber S, Kniest A, Diehl A, et al. Neuropsychological functioning of opiate-dependent patients: A nonrandomized comparison of patients preferring either buprenorphine or methadone maintenance treatment. Am J Drug Alcohol Abuse. 2008 ; 34: 584-593
44. Lombardo WK, Lombardo B, Goldstein A. Cognitive functioning under moderate and low dosage methadone maintenance. Int J Addict. 1976 ; 11: 389-401
45. Marsch LA. The efficacy of methadone maintenance interventions in reducing illicit opiate use, HIV risk behavior and criminality: A meta-analysis. Addiction. 1998 ; 93: 515-532
46. Martins SS, Storr CL, Zhu H, et al. Correlates of extramedical use of OxyContin® versus other analgesic opioids among the US general population. Drug Alcohol Depend. 2009 ; 99: 58-67
47. McDermott PA, Brown L, Zaballero A, et al. Construct refinement and confirmation for the addiction severity index. Psychol Assess. 1996 ; 8: 182-189
48. McLellan AT, Luborsky L, O'Brien CP, et al. An improved diagnostic instrument for substance abuse patients: The Addiction Severity Index. J Nerv Ment Dis. 1980 ; 168: 26-33
49. Educational Attainment in the Adult Population. Wellington. New Zealand: Ministry of Education ; 2010 :
50. Mintzer MZ, Stitzer ML. Cognitive impairment in methadone maintenance patients. Drug Alcohol Depend. 2002 ; 67: 41-51
51. Mintzer MZ, Copersino ML, Stitzer ML. Opioid abuse and cognitive performance. Drug Alcohol Depend. 2005 ; 78: 225-230
52. Novick DM, Ochshorn M, Ghali V, et al. Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long-term methadone maintenance patients. J Pharmacol Exp Ther. 1989 ; 250: 606-610
53. Paul R, Lawrence J, Williams L, et al. Preliminary validity of 'IntegNeuro': A new computerized battery of neurocognitive tests. Int J Neurosci. 2005 ; 115: 1549-1567
54. Pirastu R, Fais R, Messina M, et al. Impaired decision-making in opiate-dependent subjects: Effect of pharmacological therapies. Drug Alcohol Depend. 2006 ; 83: 163-168
55. Prosser J, Cohen LJ, Steinfeld M, et al. Neuropsychological functioning in opiate-dependent subjects receiving and following methadone maintenance treatment. Drug Alcohol Depend. 2006 ; 84: 240-247
56. Prosser J, London E, Galynker I. Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: Performance and neuroimaging results. Drug Alcohol Depend. 2009 ; 104: 228-240
57. Rapeli P, Fabritius C, Alho H, et al. Methadone vs. buprenorphine/ naloxone during early opioid substitution treatment: A naturalistic comparison of cognitive performance relative to healthy controls. BMC Clin Pharmacol. 2007 ; 7: 5
58. Rapeli P, Fabritius C, Kalska H, et al. Memory function in opioid-dependent patients treated with methadone or buprenorphine along with benzodiazepine: Longitudinal change in comparison to healthy individuals. Subst Abuse Treat Prev Policy. 2009 ; 4: 1-15
59. Reitan R. Validity of the Trail Making test as an indicator of organic brain damage. Percept Mot Skills. 1958 ; 8: 271-276
60. Riddle D Brain Aging: Models, Methods, and Mechanisms. Boca Raton: CRC Press ; 2007 :
61. Rothenberg S, Meyer RE, Rauss B, et al. Performance differences between addicts and non-addicts. Psychopharmacology. 1977 ; 52: 299-306
62. Rounsaville BJ, Anton SF, Carroll K, et al. Psychiatric diagnoses of treatment-seeking cocaine abusers. Arch Gen Psychiatry. 1991 ; 48: 43-51
63. Sankararaman A, Masiulis I, Richardson DR, et al. Methadone does not alter key parameters of adult hippocampal neurogenesis in the heroin-naïve rat. Neurosci Lett. 2012 ; 516: 99-104
64. Schindler SD, Ortner R, Peternell A, et al. Maintenance therapy with synthetic opioids and driving aptitude. European Addiction Research. 2004 ; 10: 80-87
65. Sellman D Improving treatment for people with addiction problems in Aotearoa New Zealand. Christchurch, New Zealand: Christchurch School of Medicine and Health Sciences ; 2006 :
66. Soyka M, Lieb M, Kagerer S, et al. Cognitive functioning during methadone and buprenorphine treatment: Results of a randomized clinical trial. J Clin Psychopharmacol. 2008 ; 28: 699-703
67. Specka M, Finkbeiner T, Lodemann E, et al. Cognitive-motor performance of methadone-maintained patients. Eur Addict Res. 2000 ; 6: 8-19
68. Australian/New Zealand Standard: Procedures for specimen collection and the detection and quantitation of drugs of abuse in urine. Sydeny: Standards Australia/Sstandards New Zealand ; 2008 :
69. Turner TH, LaRowe S, Horner MD, et al. Measures of cognitive functioning as predictors of treatment outcome for cocaine dependence. J Subst Abuse Treat. 2009 ; 37: 328-334
70. Verdejo A, Toribio I, Orozco C, et al. Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers. Drug Alcohol Depend. 2005 ; 78: 283-288
71. Verdejo-García A, López-Torrecillas F, Giménez CO, et al. Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. Neuropsychol Rev. 2004 ; 14: 1-41
72. Williams LM, Hermens DF, Thein T, et al. Using brain-based cognitive measures to support clinical decisions in ADHD. Pediatr Neurol. 2010 ; 42: 118-126
73. Reliability and validity studies of the WHO-Composite International Diagnostic Interview (CIDI): A critical review. J Psychiatr Res. 1994 ; 28: 57-84