Tanshinone IIA suppresses lung injury and apoptosis, and modulates protein kinase B and extracellular signal-regulated protein kinase pathways in rats challenged with seawater exposure

Clinical and Experimental Pharmacology and Physiology

Volumn 38, Issue 4, 2011, Pages 269-277

  Li, Jia Huan ^a,b   Xu, Min ^c   Xie, Xiao Yan ^a   Fan, Qi Xin ^a   Mu, De Guang ^a   Zhang, Yong ^a   Cao, Fa Le ^a   Wang, Yan Xia ^c   Zhao, Peng Tao ^c   Zhang, Bo ^c   Jin, Fa Guang ^a   Li, Zhi Chao ^b,d  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Extracellular signal regulated protein kinase 1 2; Lung injury; Protein kinase B; Seawater exposure; Tanshinone IIA

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BCL 2; PROTEIN KINASE B; SEA WATER; TANSHINONE IIA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD GAS ANALYSIS; BLOOD VESSEL PERMEABILITY; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVATION; HISTOPATHOLOGY; LUNG EDEMA; NONHUMAN; PROTEIN EXPRESSION; RAT; RESPIRATORY FAILURE; SIGNAL TRANSDUCTION;

ACUTE LUNG INJURY; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CASPASE 3; DITERPENES, ABIETANE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; OXYGEN; PARTIAL PRESSURE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SEAWATER;

EID: 79953066021     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05498.x     Document Type: Article

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