GNAS is frequently mutated in both low-grade and high-grade disseminated appendiceal mucinous neoplasms but does not affect survival

Human Pathology

Volumn 45, Issue 8, 2014, Pages 1737-1743

  Singhi, Aatur D ^a   Davison, Jon M ^a   Choudry, Haroon A ^a   Pingpank, James F ^a   Ahrendt, Steven A ^a   Holtzman, Matthew P ^a   Zureikat, Amer H ^a   Zeh, Herbert J ^a   Ramalingam, Lekshmi ^a   Mantha, Geeta ^a   Nikiforova, Marina ^a   Bartlett, David L ^a   Pai, Reetesh K ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Appendix; Disseminated peritoneal adenomucinosis; GNAS; Low grade mucinous neoplasm; Mucinous adenocarcinoma; Peritoneal mucinous carcinomatosis; Pseudomyxoma peritonei

Indexed keywords

GNAS PROTEIN; K RAS PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ADULT; AGED; APPENDIX TUMOR; ARTICLE; CANCER GENETICS; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; HIGH GRADE APPENDICEAL MUCINOUS NEOPLASM; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LOW GRADE APPENDICEAL MUCINOUS NEOPLASM; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; OVERALL SURVIVAL; PERINEURAL INVASION; PROTEIN ANALYSIS; SIGNET RING CARCINOMA; TUMOR INVASION; WILD TYPE;

APPENDIX; DISSEMINATED PERITONEAL ADENOMUCINOSIS; GNAS; LOW-GRADE MUCINOUS NEOPLASM; MUCINOUS ADENOCARCINOMA; PERITONEAL MUCINOUS CARCINOMATOSIS; PSEUDOMYXOMA PERITONEI;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; APPENDICEAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM GRADING; PROGNOSIS; YOUNG ADULT;

EID: 84904621566     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.04.018     Document Type: Article

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